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Xeljanz XR Price, Generic and Savings
- Lowest U.S. online pharmacy price
- $172.15 per tablet$15,493.26 for 90 days (90 tablets), shipping included · FDA-approved brand Xeljanz XR 11 mg · ships within the U.S.
- Lowest international online pharmacy price
- $11.58 per tablet$1,041.75 for 90 days (90 tablets), plus shipping (fee not published) · brand Xeljanz XR 11 mg, not FDA-approved · ships from Mauritius
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Quick answerAs of Nov 12, 2026, brand Xeljanz XR 11 mg costs from $2,711.53 for 90 days at online pharmacies abroad we compared, vs. $18,219.42 at the U.S. list price ($6,073.14 for 30 tablets). Generic tofacitinib ER went on sale in the U.S. in 2026.
Name check: This page is for once-daily Xeljanz XR tablets. Regular Xeljanz (5 and 10 mg, twice daily) has its own page; the label says not to swap the two without your prescriber.
Compare Xeljanz XR prices from licensed online pharmacies
For comparison U.S. pharmacy list price: $18,219.42 for 90 days ($202.44 per tablet), brand Xeljanz XR before insurance. The prices below are from U.S. pharmacies that publish cash prices and from licensed online pharmacies outside the U.S.
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per tabletOnline pharmacy A | Xeljanz XR (Turkey pack, ships from Mauritius)11 mg · brand · Filled in MauritiusProduct of Turkey | $972.30for 84 tablets$11.58 per tablet | Fee not publishedDelivery time not stated | $972.30 for 84 days= $1,041.75 for 90 days+ shippingSave 94%Worked out from an 84-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy B | Xeljanz XR (Turkey pack, ships from Mauritius)11 mg · brand · Filled in MauritiusProduct of Turkey | $982.99for 84 tablets$11.70 per tablet | Fee not publishedDelivery time not stated | $982.99 for 84 days= $1,053.20 for 90 days+ shippingSave 94%Worked out from an 84-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | Xeljanz XR (Turkey pack, ships from Mauritius)11 mg · brand · Filled in MauritiusProduct of Turkey | $2,520.81for 84 tablets$30.01 per tablet | $9.95Delivery time not stated | $2,530.76 for 84 days= $2,711.53 for 90 daysSave 85%Worked out from an 84-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy D | Tofacitinib XRNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.11 mg · generic · Filled in CanadaMaker listed by pharmacy: Taro Pharmaceuticals Ltd. | $4,009.99for 90 tablets$44.56 per tablet | FreeDelivery time not stated | $4,009.99 for 90 days= $4,009.99 for 90 daysSave 78%incl. $0 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy D | Xeljanz XR11 mg · brand · Filled in CanadaMaker listed by pharmacy: Pfizer | $5,940.69for 90 tablets$66.01 per tablet | FreeDelivery time not stated | $5,940.69 for 90 days= $5,940.69 for 90 daysSave 67%incl. $0 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | Xeljanz XR 11 mg (the pharmacy lists it as Xeljanz)11 mg · brand · Filled in CanadaMaker listed by pharmacy: Pfizer | $6,072.29for 90 tablets$67.47 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $6,087.24 for 90 days= $6,087.24 for 90 daysSave 67%incl. $14.95 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed Canadian pharmacy F | Xeljanz XR (tofacitinib)11 mg · brand · Filled in CanadaProduct of Canada | $2,089.95per 30 tablets · 3 packs = $6,269.85$69.67 per tablet | $14.99Delivery time not stated | $6,284.84 for 90 days= $6,284.84 for 90 daysSave 66%incl. $14.99 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy G | XELJANZ XR 11MG TABLET 90 (BRAND FROM CANADA)11 mg · brand · Filled in CanadaProduct of Canada | $8,410for 90 tablets$93.44 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $8,424.95 for 90 days= $8,424.95 for 90 daysSave 54%incl. $14.95 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy H | Tofacitinib XR 11mg Tablet11 mg · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 12, 2026 | $15,493.26for 90 tablets$172.15 per tablet | FreePharmacy's estimate: 3–5 business days | $15,493.26 for 90 days= $15,493.26 for 90 daysSave 15%incl. $0 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy A | Tofacitinib Citrate (India pack, ships from Mauritius)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.11 mg · generic · Filled in MauritiusProduct of India | $192.30for 100 tablets$1.92 per tabletOver 3-month supply | Fee not publishedDelivery time not stated | $192.30 for 100 days= $173.07 for 90 days+ shippingSave 99%Worked out from a 100-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy B | Tofacitinib Citrate (India pack, ships from Mauritius)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.11 mg · generic · Filled in MauritiusProduct of India | $202.99for 100 tablets$2.03 per tabletOver 3-month supply | Fee not publishedDelivery time not stated | $202.99 for 100 days= $182.69 for 90 days+ shippingSave 99%Worked out from a 100-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | Tofacitinib Citrate (India pack, ships from Mauritius)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.11 mg · generic · Filled in MauritiusProduct of India | $335.08for 100 tablets$3.35 per tabletOver 3-month supply | $9.95Delivery time not stated | $345.03 for 100 days= $310.53 for 90 daysSave 98%Worked out from a 100-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Xeljanz XR from Canada?
90-day cost = 90 tablets at the usual dose of 1 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 12, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
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Join to See PharmaciesAlready a member? Sign inXeljanz XR price by strength
| Strength | Lowest brand90 days | Lowest generic abroad90 days, not FDA-approved | Price per tablet |
|---|---|---|---|
| Xeljanz XR 11 mg | $2,711.53 | $4,009.99 | $30.01 brand · $44.56 generic |
Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per tablet is for that lowest pack, before shipping. Prices checked Nov 12, 2026.
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90-day prices from 5 licensed pharmacies abroad shipping to the U.S.: $2,711.53 to $8,424.95, any strength, shipping included.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Xeljanz XR · Similar drugs · Uses · FAQ
Xeljanz XR (tofacitinib extended-release) once-a-day tablets for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and ulcerative colitis. FDA-approved generics are sold in the U.S.
Other Ways to Pay for Xeljanz XR
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
Checking more than one medicine? Use the free Medicare Drug Cost Check.
Other ways to pay, useful if you have insurance or Medicare:
- TrumpRx.gov: The federal TrumpRx site lists brand Xeljanz XR at $3,204.00 for 30 tablets of 11 mg or 22 mg (original price $6,407.10), checked November 11, 2026. You print or save a coupon and show it at a retail pharmacy that carries Xeljanz XR. It can't be used with Medicare or Medicaid coverage, and a cash purchase won't count toward a Medicare plan's deductible or the $2,100 yearly cap. With private insurance, ask your plan whether a cash purchase counts toward your deductible. (TrumpRx.gov)
We list these because they may save you money. No one pays us to include them. Prices and eligibility rules change, so confirm before you buy. Checked Nov 12, 2026.
Xeljanz XR cost at a glance
- U.S. list price: $6,073.14 for a bottle of 30 brand Xeljanz XR tablets, the same for 11 mg and 22 mg. That's about $202.44 a tablet, or $18,219.42 for 90 days (the maker's wholesale price before discounts; Texas DSHS).
- TrumpRx: the federal TrumpRx site lists brand Xeljanz XR at $3,204.00 for 30 tablets (11 mg or 22 mg), with a coupon you show at a retail pharmacy. It can't be used with Medicare or Medicaid (TrumpRx.gov, checked 2026-11-11).
- Generic Xeljanz XR is sold in the U.S. The FDA has approved generic tofacitinib extended-release tablets from several makers, rated equivalent to Xeljanz XR; Zydus's went on sale in May 2026 (FDA Orange Book; FDA NDC Directory). The 2026 Texas filing has no list price for them yet.
- How we count: 1 tablet a day. The label's dose is 11 mg once a day; for ulcerative colitis, 22 mg once a day may be used for up to 16 weeks at the start.
- From online pharmacies abroad: $2,711.53 to $8,424.95 for 90 days of brand Xeljanz XR 11 mg, shipping included (checked Nov 12, 2026). Packs made for other countries are not FDA-approved.
How much does Xeljanz XR cost in the U.S.?
| If you have | What Xeljanz XR costs | Source |
|---|---|---|
| No insurance (brand list price) | $6,073.14 for 30 tablets of Xeljanz XR 11 mg or 22 mg. Pharmacies may charge more. | Texas DSHS 2026 WAC report |
| No insurance (TrumpRx coupon) | $3,204.00 for 30 tablets of brand Xeljanz XR 11 mg or 22 mg with the TrumpRx coupon at a retail pharmacy (checked November 11, 2026). Not for Medicare or Medicaid. | TrumpRx.gov |
| No insurance (generic) | FDA-approved generic tofacitinib extended-release has been sold since May 2026; we found no published list price yet. Ask your pharmacist for the cash price. | FDA NDC Directory |
| Private or employer insurance | Your copay depends on your plan's drug list. Pfizer's co-pay card may lower it for brand Xeljanz XR (see savings programs). | Xeljanz.com |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Brand Xeljanz XR lists at $6,073.14 for 30 tablets in the Texas 2026 drug price filing (Texas DSHS). TrumpRx gives the original price as $6,407.10 for 30, so the list price may have gone up since that filing (TrumpRx.gov). These are list prices (the maker's wholesale price before discounts); what a pharmacy charges can differ.
Xeljanz XR cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Xeljanz XR or generic tofacitinib extended-release depends on your plan's drug list.
| Medicare Part D | What Xeljanz XR costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Xeljanz XR coupons and savings programs
eDrugSearch does not offer its own Xeljanz XR coupons. eDrugSearch has no coupons of its own. These programs can help with the cost of Xeljanz XR:
- XELJANZ Co-Pay Savings Program (Pfizer): for people with commercial insurance who have been prescribed Xeljanz or Xeljanz XR. You may pay as little as $0 a month; Pfizer says yearly savings may reach $4,000 to $15,000, depending on your insurance. Not for people in federal or state health programs such as Medicare or Medicaid, and not for cash-paying patients. Call XELSOURCE at 1-844-935-5269. (Xeljanz.com)
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Xeljanz XR?
Yes. The FDA has approved generic tofacitinib extended-release tablets from several makers, rated equivalent to Xeljanz XR. Zydus's were the first listed for sale, on May 20, 2026; more makers followed in June 2026.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 11 mg | Yes | Zydus, Ajanta, Aurobindo, Apotex, Biocon, Dexcel, Teva and others | May 20, 2026 |
| 22 mg | Yes | Zydus, Ajanta, Teva | May 20, 2026 |
Outside the U.S.: Online pharmacies abroad may also sell generic tofacitinib made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: FDA Orange Book: tofacitinib extended-release tablets. As of Nov 12, 2026.
Compare Xeljanz XR with similar drugs
Other arthritis and immune medicines people often look up alongside Xeljanz XR, including Xeljanz, generic tofacitinib, Rinvoq, Olumiant, Otezla, Arava and Trexall. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Xeljanztofacitinib | Rheumatoid arthritis and ulcerative colitis medicine (JAK inhibitor) | $177.06 for 90 days | See prices |
| Tofacitinibtofacitinib | Rheumatoid arthritis and ulcerative colitis medicine (JAK inhibitor), generic of Xeljanz | $177.06 for 90 days | See prices |
| Rinvoqupadacitinib | Immune system medicine (JAK inhibitor) | $940.70 for 90 days | See prices |
| Olumiantbaricitinib | Immune system medicine (JAK inhibitor) | $191.67 for 90 days | See prices |
| Otezlaapremilast | Psoriasis and psoriatic arthritis medicine (PDE4 inhibitor) | $88.64 for 90 days | See prices |
| Aravaleflunomide | Rheumatoid arthritis medicine (DMARD) | $57.13 for 90 days | See prices |
| Trexallmethotrexate | Antimetabolite (used for arthritis, psoriasis and some cancers) | From $0.60 per tablet | See prices |
Lowest price from licensed pharmacies shipping to the U.S., any strength: 90-day prices include shipping; prices per unit are before shipping. Only your doctor can decide whether another drug is right for you.
What is Xeljanz XR used for?
Xeljanz XR is a JAK inhibitor, a medicine that calms parts of the immune system that drive inflammation. According to its FDA label (DailyMed), it is used in adults who didn't do well on, or couldn't take, one or more TNF blockers, to treat:
- Moderately to severely active rheumatoid arthritis.
- Active psoriatic arthritis.
- Active ankylosing spondylitis.
- Moderately to severely active ulcerative colitis.
The label's dose is 11 mg once a day; for ulcerative colitis it may start at 22 mg once a day for 8 to 16 weeks. Xeljanz XR has a boxed warning about serious infections, death, cancer, major heart events and blood clots, and the label says to test for tuberculosis before starting. Your prescriber decides which medicine is right for you.
Is it safe to order Xeljanz XR from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Xeljanz XR, compare the TrumpRx price and the U.S. generic before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. Health Canada lists Xeljanz XR 11 mg from Pfizer Canada as marketed (Health Canada Drug Product Database, checked 2026-11-12).
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much is Xeljanz XR without insurance?
The U.S. list price of brand Xeljanz XR is $6,073.14 for 30 tablets of 11 mg or 22 mg. The TrumpRx coupon price is $3,204.00 for 30 (checked November 11, 2026). Online pharmacies abroad charged from $2,711.53 for 90 days of brand Xeljanz XR 11 mg in our latest check (Nov 12, 2026).
Is there a generic Xeljanz XR?
Yes. FDA-approved generic tofacitinib extended-release tablets went on sale in the U.S. in May 2026, from several makers. Ask your pharmacist whether a generic can fill your prescription.
What's the difference between Xeljanz and Xeljanz XR?
Both contain tofacitinib. Xeljanz XR is an extended-release tablet taken once a day (11 mg or 22 mg); regular Xeljanz is taken twice a day (5 mg or 10 mg). The label says only your prescriber should switch you between them.
Is there a Xeljanz XR coupon?
With commercial insurance, Pfizer's Xeljanz Co-Pay Savings Program may lower your cost to as little as $0 a month. Without insurance, the TrumpRx coupon lists Xeljanz XR at $3,204.00 for 30 tablets. Neither can be used with Medicare or Medicaid.
How much does Xeljanz XR cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help.
What strengths does Xeljanz XR come in?
Xeljanz XR comes in 11 mg and 22 mg extended-release tablets, in bottles of 30. Both list at the same U.S. price.
Sources
- Xeljanz/Xeljanz XR U.S. prescribing information (DailyMed) (Pfizer label, version 55, effective 2026-09-25: RA, PsA, AS, UC after TNF blocker; XR 11 mg once daily, UC induction 22 mg once daily 8-16 weeks; boxed warning; XR not substitutable with Xeljanz; XR 11 and 22 mg bottles of 30)
- Drugs@FDA: Xeljanz XR (NDA 208246) (approved February 23, 2016; 11 mg and 22 mg Prescription AB)
- FDA NDC Directory: Xeljanz XR (0069-0501 (11 mg) and 0069-0502 (22 mg), Pfizer, active; checked 2026-11-12)
- Texas DSHS: 2026 annual WAC report (Pfizer Xeljanz XR 00069050130 (11 mg x30) and 00069050230 (22 mg x30) $6,073.14 each; no generic tofacitinib ER rows)
- TrumpRx.gov: Xeljanz (Tablet XR 11 mg and 22 mg x30: $3,204.00 (original price $6,407.10, stated as WAC); coupon at retail pharmacies; data fetched 2026-11-11 (SP/trx/TRUMPRX.json))
- Xeljanz.com: savings and support (co-pay program for commercially insured patients, as little as $0 a month, annual savings up to $4,000-$15,000 depending on insurance; federal and state beneficiaries and cash payers ineligible; XELSOURCE 1-844-935-5269; read 2026-11-12)
- FDA NDC Directory: generic tofacitinib (ER generics: Zydus 70710-1353/1727 and 70771-1627/1628 from 2026-05-20; Ajanta, Aurobindo, Biocon, Edenbridge (Dexcel), Apotex from 2026-06-03; Orient/Exelan, Padagis, ScieGen later in June-July 2026)
- Drugs@FDA: tofacitinib generics
- FDA Orange Book: tofacitinib extended-release tablets
- Health Canada Drug Product Database: Xeljanz XR (DIN 02470608, Pfizer Canada, Marketed)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.
