Generic Xeljanz (tofacitinib) Price

Tofacitinib price by strength

Tofacitinib names

- Brand name: Xeljanz and Xeljanz XR (Pfizer)
- Generic name: tofacitinib
- Names in Canada: Xeljanz, Xeljanz XR, plus generics such as Auro-Tofacitinib, Sandoz Tofacitinib, Taro-Tofacitinib, Jamp Tofacitinib, Pms-Tofacitinib and Taro-Tofacitinib XR (Health Canada Drug Product Database, marketed products, checked Oct 29, 2026)

Tofacitinib packs made for other countries are not FDA-approved.

Tofacitinib FAQ

Brand vs. generic: cost for 90 days

Lowest in this comparison: Generic tofacitinib 5 mg tablet, U.S. pharmacy cash price.

90 days = 90 daily doses of 5 mg tablet. Generic sold abroad is not FDA-approved and is not in this box. Your price with insurance or Medicare depends on your plan.

See brand Xeljanz prices

Tofacitinib cost with Medicare in 2026

Each Part D plan has its own list of covered drugs and copays, so what you pay for tofacitinib depends on your plan (Medicare Plan Finder). In 2026, Part D plans can have a yearly deductible of up to $615, and your out-of-pocket costs for covered drugs are capped at $2,100 a year ($2,400 in 2027) (Medicare.gov). Pfizer's co-pay program and the TrumpRx coupon are for brand Xeljanz and can't be used with Medicare.

Savings programs from the maker

eDrugSearch does not offer its own Tofacitinib coupons. Pfizer's Xeljanz Co-Pay Savings Program and the TrumpRx.gov coupon are for brand Xeljanz only (see the brand page). These programs can lower what you pay for generic tofacitinib:

• Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
• Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
• Costco Pharmacy member prices: Costco publishes member prices for many prescriptions, for people with a Costco membership. Non-members can also use Costco pharmacies and pay the regular cash price. Member prices can't be used with insurance, Medicare or Medicaid claims. (Costco Pharmacy)
• Amazon Pharmacy Prime and RxPass: Amazon Pharmacy offers Prime members discounts on many prescriptions, and RxPass, for Prime members, covers a set list of generics for a flat monthly fee. Prime is not required to use Amazon Pharmacy. Prime savings have limits for people with Medicare, Medicaid or Tricare, and RxPass is not open to people with Medicaid or CHIP. (Amazon Pharmacy)
• Discount cards: Discount cards (for example GoodRx or SingleCare) may lower the price at local pharmacies; prices vary by pharmacy and ZIP code.

When people choose brand Xeljanz

Some people get brand Xeljanz instead of generic tofacitinib. Common reasons:

• A prescription marked “dispense as written” (or “brand medically necessary”) tells the pharmacy to fill brand Xeljanz, not a generic. State laws set the rules for generic substitution.
• With commercial insurance, Pfizer says eligible patients may pay as little as $0 a month for brand Xeljanz with its co-pay program, up to a yearly limit (Pfizer). It can't be used with Medicare or Medicaid.
• Some insurance and Medicare drug plans cover the brand and the generic at different copays, or cover only one of them. Your plan's drug list shows which.

Your prescriber decides which medicine is right for you.

Compare prices for your other medicines

• Xeljanz prices from $177.06 for 90 days
• Rinvoq prices from $940.70 for 90 days
• Olumiant prices from $191.67 for 90 days

Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength.

What is Tofacitinib used for?

Tofacitinib is a Janus kinase (JAK) inhibitor, the same medicine as in Xeljanz. According to the Xeljanz FDA label (prescribing information), it is used for people who have had an inadequate response to, or could not tolerate, one or more TNF blockers:

• Adults with moderately to severely active rheumatoid arthritis.
• Active psoriatic arthritis in adults, and in children 2 years and older (tablets and oral solution only).
• Adults with active ankylosing spondylitis.
• Adults with moderately to severely active ulcerative colitis.
• Children 2 years and older with active polyarticular course juvenile idiopathic arthritis (tablets and oral solution only).

The label's usual dose for rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis is 5 mg twice a day or 11 mg extended-release once a day; the 10 mg and 22 mg doses are for ulcerative colitis. Tofacitinib has a boxed warning, the FDA's strongest, for serious infections (including tuberculosis), a higher rate of death, cancers (including lymphoma and lung cancer), heart attack and stroke, and blood clots. Check the label that comes with your medicine. Your prescriber decides which medicine is right for you.