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Trexall Price, Generic and Savings
- Lowest price per tablet at U.S. online pharmacies
- Not available
- Lowest price per tablet at online pharmacies abroad
- $1.33 per tabletIn a pack of 90 tablets for $119.37 (before shipping) · generic methotrexate 7.5 mg, not FDA-approved · ships from India
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Quick answerAs of Nov 12, 2026, generic methotrexate 7.5 mg costs from $1.33 per tablet at online pharmacies abroad, before shipping. Brand Trexall 7.5 mg lists at $1,037.90 for 30 tablets in the U.S., about $34.60 each. U.S. generic methotrexate comes only as 2.5 mg tablets.
Name check: Generic methotrexate 2.5 mg tablets, Xatmep and Jylamvo (liquids) and methotrexate shots are separate products. Only Trexall tablets are priced here.
Compare Trexall prices from licensed online pharmacies
| Pharmacy | Medication | Pack | Price per unit | Pack price | Shipping & delivery | Total with shipping | Buy |
|---|---|---|---|---|---|---|---|
| Lowest price per unitOnline pharmacy A | Generic Equivalent to Trexall 5mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.5 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: IPCA laboratories | 90 tablets2 other pack sizes
| $0.60 per tablet | $53.75 | $14.95Pharmacy's estimate: 4–6 weeks | $68.70Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy B | Generic Equivalent To Trexall 5mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.5 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: IPCA laboratories | 90 tablets2 other pack sizes
| $0.61 per tablet | $55.05 | $14.95Pharmacy's estimate: 4–6 weeks | $70Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy C | Generic Equivalent To Trexall 5mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.5 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: IPCA laboratories | 90 tablets2 other pack sizes
| $0.66 per tablet | $59.19 | $14.95Pharmacy's estimate: 4–6 weeks | $74.14Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy D | RHEUMATREX 5MG TABLET 90 (GENERIC METHOTREXATE FROM INDIA)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.5 mg · generic · Filled in IndiaMade for sale in India.Product of India | 90 tablets | $0.75 per tablet | $67.50 | $14.95Pharmacy's estimate: 4–6 weeks | $82.45Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy E | MethotrexateNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.5 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Sun Pharmaceuticals | 90 tablets2 other pack sizes
| $0.77 per tablet | $68.93 | $14.95Pharmacy's estimate: 4–6 weeks | $83.88Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy B | Generic Equivalent To Trexall 10mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.10 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: IPCA laboratories | 90 tablets2 other pack sizes
| $0.93 per tablet | $83.70 | $14.95Pharmacy's estimate: 4–6 weeks | $98.65Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy D | RHEUMATREX 10MG TABLET 100 (GENERIC METHOTREXATE FROM UK)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.10 mg · generic · Filled in UKProduct of UK | 100 tablets | $0.95 per tablet | $95 | $14.95Pharmacy's estimate: 4–6 weeks | $109.95Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy A | Generic Equivalent to Trexall 10mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.10 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: IPCA laboratories | 90 tablets2 other pack sizes
| $0.98 per tablet | $87.86 | $14.95Pharmacy's estimate: 4–6 weeks | $102.81Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy C | Generic Equivalent To Trexall 10mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.10 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: IPCA laboratories | 90 tablets2 other pack sizes
| $1.00 per tablet | $90 | $14.95Pharmacy's estimate: 4–6 weeks | $104.95Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy B | Generic Equivalent To Trexall 7.5mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.7.5 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Cipla Limited | 90 tablets2 other pack sizes
| $1.33 per tablet | $119.37 | $14.95Pharmacy's estimate: 4–6 weeks | $134.32Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy C | Generic Equivalent To Trexall 7.5mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.7.5 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Cipla Limited | 90 tablets2 other pack sizes
| $1.43 per tablet | $128.36 | $14.95Pharmacy's estimate: 4–6 weeks | $143.31Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy B | Generic Equivalent To Trexall 15mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.15 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: IPCA laboratories | 90 tablets2 other pack sizes
| $1.43 per tablet | $128.87 | $14.95Pharmacy's estimate: 4–6 weeks | $143.82Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy C | Generic Equivalent To Trexall 15mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.15 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: IPCA laboratories | 90 tablets2 other pack sizes
| $1.54 per tablet | $138.57 | $14.95Pharmacy's estimate: 4–6 weeks | $153.52Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy A | Generic Equivalent to Trexall 15mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.15 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: IPCA laboratories | 90 tablets2 other pack sizes
| $1.64 per tablet | $147.23 | $14.95Pharmacy's estimate: 4–6 weeks | $162.18Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy F | Generic Mexate 7.5mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.7.5 mg · generic · Filled in IndiaMade for sale in India.Product of India | 90 tablets2 other pack sizes
| $1.85 per tablet | $166.87 | Fee not publishedDelivery time not stated | $166.87+ shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy E | MethotrexateNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.10 mg · generic · Filled in New ZealandMaker listed by pharmacy: Rex | 24 tablets2 other pack sizes
| $2.88 per tablet | $69.13 | $14.95Pharmacy's estimate: 4–6 weeks | $84.08Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy G | RHEUMATREX (generic methotrexate)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.10 mg · generic · Filled in New ZealandProduct of New Zealand | 24 tablets2 other pack sizes
| $3.00 per tablet | $71.98 | FreeDelivery time not stated | $71.98Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy H | RHEUMATREX (generic methotrexate)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.10 mg · generic · Filled in New ZealandProduct of New Zealand | 24 tablets2 other pack sizes
| $3.10 per tablet | $74.37 | FreeDelivery time not stated | $74.37Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitLicensed U.S. pharmacy I | Trexall 15mg Tablets, 30 Count Bottle15 mg · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 12, 2026 | 90 tablets2 other pack sizes
| $78.73 per tablet | $7,086 | $5Pharmacy's estimate: 2–8 business days | $7,091Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Trexall from Canada?
| Strength | Lowest brandper unit, before shipping | Lowest generic abroadper unit, not FDA-approved |
|---|---|---|
| Trexall 5 mg | — | $0.60 per tablet |
| Trexall 7.5 mg | — | $1.33 per tablet |
| Trexall 10 mg | — | $0.93 per tablet |
| Trexall 15 mg | — | $1.43 per tablet |
Each row is one product from one pharmacy, shown in the pack size with the lowest price per unit; its other pack sizes are listed under “other pack sizes”. Price per unit = the pack price divided by the units in the pack, before shipping; we sort by it and don't assume how long a pack lasts. Total with shipping = the pack price plus the pharmacy's shipping fee for one order. Prices checked Nov 12, 2026 on each pharmacy's website, in U.S. dollars (converted when a pharmacy prices in Canadian dollars). The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
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Prices per tablet from 7 licensed pharmacies abroad shipping to the U.S.: $0.60 to $3.10, any strength, before shipping.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Trexall · Similar drugs · Uses · FAQ
Trexall (methotrexate) 5, 7.5, 10 and 15 mg tablets for rheumatoid arthritis, severe psoriasis and some cancers. Generic methotrexate is sold in the U.S. as 2.5 mg tablets.
Trexall cost at a glance
- No generic at Trexall's strengths. No other company sells methotrexate tablets in 5, 7.5, 10 or 15 mg in the U.S. Generic methotrexate 2.5 mg tablets are sold by many companies, and a 2026 drug price filing lists 100 of them from $20.14 (Accord, AvKARE) (Texas DSHS).
- U.S. list price: brand Trexall comes in bottles of 30 tablets, listed at $692.10 (5 mg), $1,037.90 (7.5 mg), $1,383.80 (10 mg) and $2,075.80 (15 mg). That's about $34.60 a tablet for 7.5 mg (the maker's wholesale price before discounts; Texas DSHS).
- How we count: per tablet. For arthritis and psoriasis, methotrexate is usually taken once a week, not every day, and the dose differs a lot from person to person and by condition. We compare prices per tablet and list each pack the way the pharmacy sells it.
- From online pharmacies abroad: $1.33 to $1.43 per tablet for generic methotrexate 7.5 mg, before shipping (checked Nov 12, 2026). We didn't find brand Trexall abroad; its U.S. list price is about $34.60 a tablet.
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
How much does Trexall cost in the U.S.?
| If you have | What Trexall costs | Source |
|---|---|---|
| No insurance (list price) | $1,037.90 for 30 tablets of brand Trexall 7.5 mg (about $34.60 a tablet). 5 mg: $692.10; 10 mg: $1,383.80; 15 mg: $2,075.80 per 30. Pharmacies may charge more. | Texas DSHS 2026 WAC report |
| No insurance (generic methotrexate 2.5 mg) | Generic methotrexate is sold in the U.S. as 2.5 mg tablets. The 2026 filing lists 100 tablets from $20.14 (Accord, AvKARE); other makers list higher. Ask your pharmacist for the cash price. | Texas DSHS 2026 WAC report |
| Private or employer insurance | Your copay depends on your plan's drug list. Ask your plan how it covers Trexall and generic methotrexate tablets. | FDA Orange Book |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Brand Trexall 7.5 mg lists at $1,037.90 for a bottle of 30 tablets in the Texas 2026 drug price filing, about $34.60 a tablet (Texas DSHS). How long a bottle lasts depends on your dose and schedule. Generic methotrexate comes as 2.5 mg tablets, and 100 of them list from $20.14 in the same filing. These are list prices (the maker's wholesale price before discounts); what a pharmacy charges can differ.
Trexall cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Trexall or generic methotrexate depends on your plan's drug list.
| Medicare Part D | What Trexall costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Trexall coupons and savings programs
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
eDrugSearch does not offer its own Trexall coupons. eDrugSearch has no coupons of its own. If you have Medicare, these programs can help:
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Trexall?
Not at Trexall's strengths. No other company sells methotrexate tablets in 5, 7.5, 10 or 15 mg in the U.S. Generic methotrexate is sold as 2.5 mg tablets by many companies. Trexall itself was approved in 2001 through the FDA's abbreviated (generic-style) pathway, and the FDA gives it no equivalence rating.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 5 mg | No | — | |
| 7.5 mg | No | — | |
| 10 mg | No | — | |
| 15 mg | No | — |
Outside the U.S.: Online pharmacies abroad may sell methotrexate tablets made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: FDA Orange Book: methotrexate sodium tablets. As of Nov 12, 2026.
Compare Trexall with similar drugs
Other medicines for rheumatoid arthritis or psoriasis taken by mouth with price pages here. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Aravaleflunomide | Rheumatoid arthritis medicine (DMARD) | From $0.47 per tablet | See prices |
| Plaquenilhydroxychloroquine | Lupus, rheumatoid arthritis and malaria medicine (antimalarial) | From $0.25 per tablet | See prices |
| Otezlaapremilast | Psoriasis and psoriatic arthritis medicine (PDE4 inhibitor) | From $0.46 per tablet | See prices |
| Xeljanztofacitinib | Rheumatoid arthritis and ulcerative colitis medicine (JAK inhibitor) | From $1.80 per tablet | See prices |
| Rinvoqupadacitinib | Immune system medicine (JAK inhibitor) | From $6.40 per tablet | See prices |
| Olumiantbaricitinib | Immune system medicine (JAK inhibitor) | From $2.13 per tablet | See prices |
Lowest price per unit, before shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Trexall used for?
Trexall (methotrexate) is a dihydrofolate reductase inhibitor. According to its FDA label (DailyMed), it is used to treat:
- Rheumatoid arthritis in adults.
- Polyarticular juvenile idiopathic arthritis in children.
- Severe psoriasis in adults.
- Acute lymphoblastic leukemia (as part of combination maintenance treatment), mycosis fungoides (a skin lymphoma) and relapsed or hard-to-treat non-Hodgkin lymphoma.
For rheumatoid arthritis, the label's starting dose is 7.5 mg once a week, adjusted as needed; for psoriasis it's 10 to 25 mg once a week. Cancer doses differ. Boxed warning: taking methotrexate every day by mistake instead of weekly has caused deaths. It can also harm an unborn baby and cause serious side effects in the bone marrow, liver, lungs, skin and kidneys. Your prescriber decides which medicine is right for you.
Is it safe to order Trexall from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Trexall, compare the U.S. price of generic methotrexate 2.5 mg tablets before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. Health Canada's drug database has no Trexall listing (Health Canada, checked 2026-11-12).
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much does Trexall cost without insurance?
Brand Trexall comes in bottles of 30 tablets. The U.S. list price is $692.10 for 5 mg, $1,037.90 for 7.5 mg, $1,383.80 for 10 mg and $2,075.80 for 15 mg. Online pharmacies abroad charged from $1.33 per tablet for generic methotrexate 7.5 mg in our latest check (Nov 12, 2026), before shipping. We didn't find brand Trexall abroad.
Is there a generic Trexall?
Not at Trexall's strengths. No other company sells 5, 7.5, 10 or 15 mg methotrexate tablets in the U.S. Generic methotrexate comes as 2.5 mg tablets. Ask your prescriber or pharmacist whether 2.5 mg tablets can work for your dose.
How much does generic methotrexate cost?
In the 2026 drug price filing, 100 generic methotrexate 2.5 mg tablets list from $20.14 (Accord, AvKARE), and other makers list higher. Those are list prices, so ask your pharmacist for the cash price.
How often do you take Trexall?
For rheumatoid arthritis and psoriasis, the label's dose is once a week, not every day. The FDA label warns that taking it daily by mistake has caused deaths. Cancer schedules differ. Follow your prescriber's directions exactly.
How much does Trexall cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help.
Sources
- TREXALL U.S. prescribing information (DailyMed) (Teva Women's Health label, version 14, effective 2026-06-17: ALL, mycosis fungoides, NHL, RA (start 7.5 mg once weekly), pJIA, severe psoriasis (10-25 mg once weekly); boxed warning incl. deaths from daily instead of weekly dosing; 5/7.5/10/15 mg tablets in bottles of 30)
- Drugs@FDA: Trexall (ANDA 040385) (Barr; 5, 7.5, 10 and 15 mg approved March 21, 2001; prescription; no TE code)
- FDA Orange Book: methotrexate sodium tablets (TREXALL A040385 (Barr) 5/7.5/10/15 mg, no TE code; 2.5 mg AB generics incl. Hikma 040054, Barr/Teva 081099, Mylan 081235, Sun 201749, Zydus 207812, Eugia 210454, Accord 213343, Elite 216453, Alembic 217552 (October 2026 data files))
- Texas DSHS: 2026 annual WAC report (TREXALL x30: 5 mg 51285-0366-01 $692.10; 7.5 mg 51285-0367-01 $1,037.90; 10 mg 51285-0368-01 $1,383.80; 15 mg 51285-0369-01 $2,075.80. Generic methotrexate 2.5 mg x100: Accord 16729-0486-01 $20.14, AvKARE 42291-0505-01 $20.14; others higher)
- FDA NDC Directory: Trexall (Teva Women's Health 51285-366/367/368/369, 30 tablets per bottle, marketing start May 3, 2001)
- Health Canada Drug Product Database (no Trexall listing; checked 2026-11-12)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.