Home › Drug Prices › Amitiza
Amitiza Cost, Coupons and Generic
- U.S. list price
- $1,213.50 for 90 days (180 capsules)The maker's price for brand Amitiza before discounts · Source: Texas DSHS 2026 WAC report
- Lowest international online pharmacy price
- $5.80 per capsule$1,044.19 for 90 days (180 capsules), shipping included · brand Amitiza 24 mcg, not FDA-approved · ships from United Kingdom
FDA-approved generic lubiprostone 24 mcg from $145.40 for 90 days at U.S. pharmacies
See all Amitiza pricesSign in or get a free account, and we'll bring you back here. Free accounts: 2 alerts · Members: unlimited
Quick answerAs of Nov 11, 2026, brand Amitiza 24 mcg costs from $1,044.19 for 90 days (180 capsules) at licensed pharmacies abroad we compared, vs. $1,213.50 at the U.S. list price ($404.50 for 60). FDA-approved generic lubiprostone is sold in the U.S., with list prices from $60 for 60 capsules.
Compare Amitiza prices from licensed online pharmacies
For comparison U.S. pharmacy list price: $1,213.50 for 90 days ($6.74 per capsule), brand Amitiza 8 mcg or 24 mcg before insurance. The prices below are from U.S. pharmacies that publish cash prices and from licensed online pharmacies outside the U.S.
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per capsuleOnline pharmacy A | Lubiprostone (India pack, ships from Mauritius)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.24 mcg · generic · Filled in MauritiusProduct of India | $108.74for 180 capsules$0.60 per capsule | Fee not publishedDelivery time not stated | $108.74 for 90 days= $108.74 for 90 days+ shippingSave 91%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleOnline pharmacy B | Lubiprostone (India pack, ships from Mauritius)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.24 mcg · generic · Filled in MauritiusProduct of India | $119.99for 180 capsules$0.67 per capsule | Fee not publishedDelivery time not stated | $119.99 for 90 days= $119.99 for 90 days+ shippingSave 90%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleLicensed U.S. pharmacy C | Lubiprostone 24mcg Gel Capsule24 mcg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $140.40for 180 capsules$0.78 per capsule | $5Pharmacy's estimate: 2–8 business days | $145.40 for 90 days= $145.40 for 90 daysSave 88%incl. $5 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleOnline pharmacy D | Generic Equivalent to Amitiza 24mcgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.24 mcg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Sun Pharma | $69.92per 90 capsules · 2 packs = $139.84$0.78 per capsule | $14.95Pharmacy's estimate: 4–6 weeks | $154.79 for 90 days= $154.79 for 90 daysSave 87%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleOnline pharmacy E | AMITIZA (India pack, ships from Mauritius)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.24 mcg · generic · Filled in MauritiusProduct of India | $181.29for 180 capsules$1.01 per capsule | FreeDelivery time not stated | $181.29 for 90 days= $181.29 for 90 daysSave 85%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleOnline pharmacy F | AMITIZANot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.24 mcg · generic · Filled in MauritiusProduct of Mauritius | $183.68for 180 capsules$1.02 per capsule | FreeDelivery time not stated | $183.68 for 90 days= $183.68 for 90 daysSave 85%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleOnline pharmacy G | LubiprostoneNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.24 mcg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Sun Pharmaceuticals Ltd | $174.24for 180 capsules$0.97 per capsule | $9.95Pharmacy's estimate: 4–6 weeks | $184.19 for 90 days= $184.19 for 90 daysSave 85%incl. $9.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleOnline pharmacy H | Lubiprostone (India pack, ships from Mauritius)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.24 mcg · generic · Filled in MauritiusProduct of India | $175.36for 180 capsules$0.97 per capsule | $9.95Delivery time not stated | $185.31 for 90 days= $185.31 for 90 daysSave 85%incl. $9.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleOnline pharmacy I | Lubiprostone (Lubiprostone) (India pack, ships from Turkey)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.24 mcg · generic · Filled in TurkeyMaker listed by pharmacy: SunMade for India | $100.28per 90 capsules · 2 packs = $200.56$1.11 per capsule | FreePharmacy's estimate: 2–3 weeks | $200.56 for 90 days= $200.56 for 90 daysSave 83%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleLicensed U.S. pharmacy J | Lubiprostone 8mcg Capsule8 mcg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $409.54per 90 capsules · 2 packs = $819.08$4.55 per capsule | FreePharmacy's estimate: 3–5 business days | $819.08 for 90 days= $819.08 for 90 daysSave 33%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleLicensed U.S. pharmacy J | Lubiprostone 24mcg Capsule24 mcg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $409.54per 90 capsules · 2 packs = $819.08$4.55 per capsule | FreePharmacy's estimate: 3–5 business days | $819.08 for 90 days= $819.08 for 90 daysSave 33%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleOnline pharmacy I | Amitiza (Lubiprostone)24 mcg · brand · Filled in United KingdomMaker listed by pharmacy: Takeda | $487.29per 84 capsules · 2 packs = $974.58$5.80 per capsule | FreePharmacy's estimate: 2–3 weeks | $974.58 for 84 days= $1,044.19 for 90 daysSave 14%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleOnline pharmacy G | Amitiza (United States pack, ships from New Zealand)8 mcg · brand · Filled in New ZealandMaker listed by pharmacy: Takeda Pharmaceutical Co.Made for United States | $439per 60 capsules · 3 packs = $1,317$7.32 per capsule | $9.95Pharmacy's estimate: 4–6 weeks | $1,326.95 for 90 days= $1,326.95 for 90 daysincl. $9.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleOnline pharmacy KU.S. shipping limited | Lubiprostone (Generic)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.24 mcg · generic · Filled in IndiaMade for sale in India.Product of India | $152per 90 capsules · 2 packs = $304$1.69 per capsule | $14.95Pharmacy's estimate: 8–14 business days | $318.95 for 90 days= $318.95 for 90 daysSave 74%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Amitiza from Canada?
90-day cost = 180 capsules at the usual dose of 2 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price of the same strength (8 mcg or 24 mcg). The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
Members see pharmacy names, ratings, visit links and price-drop alerts.
Join to See PharmaciesAlready a member? Sign inAmitiza price by strength
| Strength | Lowest brand90 days | Lowest generic abroad90 days, not FDA-approved | Price per capsule |
|---|---|---|---|
| Amitiza 8 mcg | $1,326.95 | — | $7.32 brand |
| Amitiza 24 mcg | $1,044.19 | $154.79 | $5.80 brand · $0.78 generic |
Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per capsule is for that lowest pack, before shipping. Prices checked Nov 11, 2026.
Get an email if the price drops. Free accounts can watch 2 medications. Sign in to watch this price
90-day prices from 6 licensed pharmacies abroad shipping to the U.S.: $154.79 to $1,326.95, any strength, shipping included.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Amitiza · Similar drugs · Uses · FAQ
Amitiza (lubiprostone) treats chronic constipation and IBS with constipation, in 8 and 24 mcg capsules. FDA-approved generic lubiprostone is sold in the U.S.
Amitiza cost at a glance
- Generic Amitiza is sold in the U.S. FDA-approved generic lubiprostone capsules (8 and 24 mcg) come from several companies (FDA Orange Book). In the Texas 2026 drug price filing, 60 capsules list at $60.00 (Par) and $63.46 (Zydus), for either strength (Texas DSHS).
- U.S. list price: $404.50 for a bottle of 60 capsules of brand Amitiza, the same for 8 mcg and 24 mcg (the maker's wholesale price before discounts). At 2 capsules a day, that is a 30-day supply (Texas DSHS).
- How we count: 2 capsules a day, so 180 capsules for 90 days. The label doses Amitiza twice a day: 24 mcg for chronic constipation and 8 mcg for IBS with constipation.
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
- From online pharmacies abroad: $1,044.19 for 90 days (180 capsules) of brand Amitiza 24 mcg, shipping included (checked Nov 11, 2026). The U.S. list price for 180 capsules is $1,213.50.
How much does Amitiza cost in the U.S.?
| If you have | What Amitiza costs | Source |
|---|---|---|
| No insurance (list price) | $404.50 for 60 capsules of brand Amitiza, 8 mcg or 24 mcg (a 30-day supply at 2 a day; $1,213.50 for 90 days). Pharmacies may charge more. | Texas DSHS 2026 WAC report |
| No insurance (generic lubiprostone) | FDA-approved generic lubiprostone is sold in the U.S. List prices for 60 capsules include $60.00 (Par), $63.46 (Zydus) and $105.76 (Teva), for either strength. Ask your pharmacist for the cash price. | Texas DSHS 2026 WAC report |
| Private or employer insurance | Your copay depends on your plan and whether it covers brand Amitiza or generic lubiprostone, which the FDA rates as equivalent to Amitiza. | FDA Orange Book |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Brand Amitiza lists at $404.50 for 60 capsules, about $6.74 a capsule (Texas DSHS). FDA-approved generic lubiprostone has been sold in the U.S. since 2021, and Par and Zydus list 60 capsules at $60.00 and $63.46 in the same filing, about $1 a capsule. List prices are what makers charge wholesalers; what a pharmacy charges you can differ.
Amitiza cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for brand Amitiza or generic lubiprostone depends on your plan's drug list.
| Medicare Part D | What Amitiza costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Amitiza coupons and savings programs
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
Checking more than one medicine? Use the free Medicare Drug Cost Check.
eDrugSearch does not offer its own Amitiza coupons. eDrugSearch has no coupons of its own. If you have Medicare, these two programs can help with the cost of brand Amitiza or generic lubiprostone:
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Amitiza?
Yes. FDA-approved generic lubiprostone capsules (8 and 24 mcg) are sold in the U.S. by several companies, including Par (an authorized generic, sold under Amitiza's own approval), Amneal, Teva, Zydus and Dr. Reddy's. Par's has been listed as on the market since January 1, 2021.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 8 mcg | Yes | Par (authorized generic), Amneal, Teva, Zydus, Dr. Reddy's and others | — |
| 24 mcg | Yes | Par (authorized generic), Amneal, Teva, Zydus, Dr. Reddy's and others | — |
Outside the U.S.: Online pharmacies abroad may also sell generic lubiprostone made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: FDA Orange Book: lubiprostone products. As of Nov 11, 2026.
Compare Amitiza with similar drugs
Other prescription medicines for chronic constipation or IBS with constipation that people compare with Amitiza. Movantik is used for constipation caused by opioids. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Linzesslinaclotide | Constipation and IBS-C medicine (guanylate cyclase-C agonist) | $317.52 for 90 days | See prices |
| Trulanceplecanatide | Constipation and IBS-C medicine (guanylate cyclase-C agonist) | $734.99 for 90 days | See prices |
| Motegrityprucalopride | Chronic constipation medicine (serotonin-4 receptor agonist) | $81.85 for 90 days | See prices |
| Ibsrelatenapanor | IBS-C medicine (NHE3 inhibitor) | Checking prices | See prices |
| Movantiknaloxegol | Medicine for constipation caused by opioid pain medicines (peripherally acting opioid antagonist) | $359.46 for 90 days | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Amitiza used for?
Amitiza (lubiprostone) draws more fluid into the bowel, which helps stool pass. According to its FDA label (DailyMed), it is used to treat:
- Chronic idiopathic constipation (long-lasting constipation with no known cause) in adults.
- Constipation caused by opioid pain medicines in adults with long-term pain that is not from active cancer.
- Irritable bowel syndrome with constipation (IBS-C) in women 18 and older.
Amitiza comes as 8 mcg and 24 mcg capsules in bottles of 60. It is taken twice a day with food and water, and the capsules are swallowed whole. The usual dose is 24 mcg twice a day for chronic or opioid-related constipation and 8 mcg twice a day for IBS-C. The label lists nausea and diarrhea among its warnings and says taking it with food may ease nausea. Your prescriber decides which medicine is right for you.
Is it safe to order Amitiza from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Amitiza, compare the U.S. price of FDA-approved generic lubiprostone before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. Amitiza was never sold in Canada: Health Canada lists it as cancelled before it reached the market (Health Canada).
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much does Amitiza cost without insurance?
The U.S. list price of brand Amitiza is $404.50 for 60 capsules, a 30-day supply at 2 a day, in the Texas 2026 drug price filing. Licensed pharmacies abroad charged from $1,044.19 for 180 capsules of brand Amitiza 24 mcg in our latest check (Nov 11, 2026). FDA-approved generic lubiprostone is also sold in the U.S.
Is there a generic for Amitiza?
Yes. The generic is lubiprostone. FDA-approved generic capsules are sold in the U.S. by several companies, including Par, Amneal, Teva and Zydus, and they have been available since 2021. Ask your pharmacist whether a generic can fill your prescription.
How much does lubiprostone cost?
In the Texas 2026 drug price filing, 60 capsules of generic lubiprostone list at $60.00 (Par), $63.46 (Zydus) and $105.76 (Teva), for 8 mcg or 24 mcg. These are list prices (the maker's wholesale price before discounts). What a pharmacy charges can differ, so ask your pharmacist.
Is there an Amitiza coupon or savings card?
eDrugSearch doesn't offer coupons of its own. FDA-approved generic lubiprostone is sold in the U.S.; ask your pharmacist for its cash price. If you have Medicare and limited income, Extra Help can lower what you pay for prescriptions.
Who makes Amitiza now?
The current FDA label names SpecGx LLC, which has listed Amitiza capsules under its own label since April 1, 2024. The FDA approval belongs to Sucampo Pharma. Older bottles carried the Takeda name.
How much does Amitiza cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help.
Can I buy Amitiza from Canada?
Amitiza was never marketed in Canada. Health Canada lists it as cancelled before it reached the market, so there is no Canadian version. The price table shows any Amitiza packs we find at licensed pharmacies abroad and where they ship from.
Sources
- Texas DSHS: 2026 annual WAC report (Amitiza 60 capsules $404.50 (SpecGx NDC 23635-0508-60 and 23635-0524-60); lubiprostone x60: Par $60.00, Zydus $63.46, Teva and Sun $105.76)
- AMITIZA U.S. prescribing information (DailyMed) (SpecGx LLC, label version 4 (effective July 10, 2026))
- FDA NDC Directory: Amitiza (SpecGx NDC 23635-508 and 23635-524, marketing start April 1, 2024; earlier Takeda listings 64764-080 and 64764-240)
- Drugs@FDA: Amitiza (NDA 021908) (approved January 31, 2006; sponsor Sucampo Pharma; 8 and 24 mcg capsules, prescription, TE code AB)
- FDA Orange Book: lubiprostone products
- FDA NDC Directory: Par lubiprostone, authorized generic (NDC 0254-3029) (marketing start January 1, 2021)
- Health Canada Drug Product Database: Amitiza (DIN 02447363 (Sucampo Pharma Americas): cancelled pre-market December 17, 2020; checked 2026-11-11)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.