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Trulance Price (plecanatide)
As of Nov 11, 2026, brand Trulance 3 mg costs from $734.99 for 90 days at licensed pharmacies abroad (ships from Canada; packs made for other countries are not FDA-approved), vs. $1,871.43 at the U.S. list price.
- Lowest U.S. online pharmacy price
- $22.72 per tablet$2,049.86 for 90 days (90 tablets), shipping included · FDA-approved brand Trulance 3 mg · ships within the U.S.
- Lowest international online pharmacy price
- $6.20 per tablet$557.82 for 90 days (90 tablets), plus shipping (fee not published) · brand Trulance 3 mg, not FDA-approved · ships from Canada
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Compare Trulance prices from licensed pharmacies
For comparison U.S. pharmacy list price: $1,871.43 for 90 days ($20.79 per tablet), brand Trulance before insurance. The prices below are from U.S. pharmacies that publish cash prices and from licensed online pharmacies outside the U.S.
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per tabletOnline pharmacy A | Trulance 3mg Tablet3 mg · brand · Filled in CanadaMaker listed by pharmacy: Maker not shown by pharmacy | $557.82for 90 tablets$6.20 per tablet | Fee not publishedDelivery time not stated | $557.82 for 90 days= $557.82 for 90 days+ shippingSave 70%incl. $0 shippingChecked Nov 7 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy B | Trulance3 mg · brand · Filled in CanadaProduct of Canada | $568.99for 90 tablets$6.32 per tablet | Fee not publishedDelivery time not stated | $568.99 for 90 days= $568.99 for 90 days+ shippingSave 70%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed Canadian pharmacy C | Trulance (Plecanatide)3 mg · brand · Filled in CanadaProduct of Canada | $720for 90 tablets$8.00 per tablet | $14.99Delivery time not stated | $734.99 for 90 days= $734.99 for 90 daysSave 61%incl. $14.99 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy D | Trulance 3mg3 mg · brand · Filled in CanadaMaker listed by pharmacy: Bausch Health Canada | $727.65for 90 tablets$8.09 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $742.60 for 90 days= $742.60 for 90 daysSave 60%incl. $14.95 shippingChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed Canadian pharmacy E | Trulance3 mg · brand · Filled in CanadaMaker listed by pharmacy: Bausch Health Canada | $776.50for 90 tablets$8.63 per tablet | $9.95Pharmacy's estimate: 3–6 weeks | $786.45 for 90 days= $786.45 for 90 daysSave 58%incl. $9.95 shippingChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy F | TRULANCE3 mg · brand · Filled in CanadaProduct of Canada | $798.62for 90 tablets$8.87 per tablet | FreeDelivery time not stated | $798.62 for 90 days= $798.62 for 90 daysSave 57%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy G | Trulance 3mg Tablets (30ct Dose Pack)3 mg · brandMaker listed by pharmacy: Salix Pharmaceuticals Inc.Ships from United StatesShips within the U.S. (no customs) · checked Nov 5, 2026 | $681.62per 30 tablets · 3 packs = $2,044.86$22.72 per tablet | $5Pharmacy's estimate: 2–8 business days | $2,049.86 for 90 days= $2,049.86 for 90 daysincl. $5 shippingChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Trulance from Canada?
90-day cost = 90 tablets at the usual dose of 1 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
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90-day prices from 4 licensed pharmacies abroad shipping to the U.S.: $734.99 to $798.62, any strength, shipping included.
Jump to: Medicare · Maker savings · Generic Trulance · Similar drugs · Uses · FAQ
Trulance (plecanatide) 3 mg tablets for IBS with constipation and chronic idiopathic constipation in adults. No generic is approved in the U.S.
Trulance price by strength
| Strength | Lowest brand90 days | Price per tablet |
|---|---|---|
| Trulance 3 mg | $734.99 | $8.00 |
Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per tablet is for that lowest pack, before shipping. Prices checked Nov 11, 2026.
Cheapest ways to get Trulance 3 mg
The cheapest ways we found to get brand Trulance 3 mg (prices checked Nov 11, 2026). The lowest 90-day cost is shaded green.
| Way to buy | Cost | Details |
|---|---|---|
| Licensed online pharmacy abroad | $734.99 for 90 days | Brand Trulance 3 mg, ships from Canada, not FDA-approved (made for another country). Shipping included, checked Nov 11, 2026. See all prices |
| U.S. pharmacy cash price | $2,049.86 for 90 days | FDA-approved brand Trulance 3 mg, ships within the U.S. (no customs). Shipping included, checked Nov 5, 2026. See all prices |
| U.S. list price | $1,871.43 for 90 days | Brand Trulance before insurance. Pharmacies may charge more. |
| Medicare Part D | Depends on your plan | Your plan’s drug list and coverage phase set your cost. Medicare costs |
Costs abroad and at U.S. pharmacies are for one order closest to 90 days, shipping included, from the price table above. Programs set their own rules, so check the terms before you count on one.
How much does Trulance cost without insurance?
Without insurance, Trulance costs $623.81 for a 30-day supply at the U.S. list price, or about $1,871.43 for 90 days. Licensed pharmacies abroad charged from $734.99 for 90 days of brand Trulance 3 mg in our latest check (Nov 11, 2026), shipping included.
Trulance cost with Medicare
In 2026, a Medicare drug plan (Part D) can charge a deductible of up to $615, and once you've spent $2,100 out of pocket on covered drugs, you pay nothing more for covered drugs that year ($2,400 in 2027) (Medicare.gov). What you pay for Trulance depends on your plan's drug list and your coverage phase. If your income is limited, Extra Help lowers drug costs: in 2026 you pay no more than $5.10 for a generic and $12.65 for a brand-name drug, with income under $23,940 ($32,460 for a married couple) and resources under $18,090 ($36,100 for a couple) (CMS). The free Medicare Prescription Payment Plan spreads costs into monthly payments, but it doesn't lower the total.
| Medicare Part D | What Trulance costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026 ($2,400 in 2027), you pay nothing more for covered drugs that year. | Medicare.gov |
Trulance cost with insurance
With private or employer insurance, what you pay for Trulance depends on your plan's drug list, deductible and copay. As little as $25 per fill, for up to a 90-day supply, with the Trulance copay program, up to 12 fills a year. A maximum savings limit applies (Salix).
Medicaid: Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office (Medicaid.gov).
Trulance patient assistance program
We haven't found a patient assistance program for Trulance. In our checks of Salix Pharmaceuticals's own pages, we found no free-medicine program that lists Trulance. If you have Medicare and a limited income, Medicare Extra Help can lower what you pay for covered drugs.
Is there a generic Trulance?
No. The FDA has not approved a generic plecanatide. The FDA Orange Book lists only Salix's Trulance 3 mg tablet (NDA 208745), and the FDA drug listing shows no generic plecanatide tablets.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 3 mg | No | — |
Outside the U.S.: If an online pharmacy abroad sells generic plecanatide, it is not FDA-approved, and the price table labels it that way.
Source: FDA Orange Book: Trulance (NDA 208745). As of Oct 26, 2026.
Trulance FAQ
How much is Trulance without insurance?
The U.S. list price is $623.81 for 30 tablets, about $1,871 for 90 days (Salix's 2026 price before discounts, as reported to the Texas Department of State Health Services). Pharmacies may charge more. Licensed pharmacies abroad charged from $734.99 for 90 days of brand Trulance 3 mg in our latest check (Nov 11, 2026), shipping included. The Trulance copay program can't be used by people paying full cash.
How much does Trulance cost with Medicare?
It depends on your Part D plan. In 2026, plans can have a deductible of up to $615, and out-of-pocket costs for covered drugs are capped at $2,100 a year ($2,400 in 2027). The Trulance copay program can't be used with Medicare, but people with limited income can apply for Extra Help.
Is there a generic Trulance?
No. The FDA has not approved a generic plecanatide, and only Salix's Trulance is listed in the FDA Orange Book. The generic name for Trulance is plecanatide.
When will generic Trulance be available?
We found no announced U.S. launch date. The FDA Orange Book lists patents for Trulance that expire between January 2028 and June 2034, but patent dates are not launch dates: a generic must first be approved by the FDA, and timing can also depend on court cases or settlements.
Is Trulance sold in Canada?
Yes. Trulance 3 mg tablets are sold in Canada under the same name by Bausch Health, Canada. Licensed Canadian pharmacies need a prescription from your doctor.
Is there a patient assistance program for Trulance?
We haven't found a patient assistance program for Trulance. In our checks of Salix Pharmaceuticals's own pages, we found no free-medicine program that lists Trulance. If you have Medicare and a limited income, Medicare Extra Help can lower what you pay for covered drugs.
Savings programs from the maker
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
eDrugSearch does not offer its own Trulance coupons. We found no Salix cash-price program for Trulance, and Trulance is not on the Bausch Health Patient Assistance Program's list of eligible medicines (checked 2026-10-26). These are the programs we could verify:
- Trulance Savings Card: for people 18 and older with commercial insurance. You may pay as little as $25 per fill, for up to a 90-day supply, for up to 12 fills a year (your share must be at least $25). A maximum savings limit applies. Not for Medicare (including Medicare Advantage), Medicaid, TRICARE, VA or other government programs, and not for people paying full cash. (Trulance savings)
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Compare Trulance with similar drugs
Other prescription medicines for IBS-C or chronic constipation that people often compare with Trulance. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Linzesslinaclotide | Constipation and IBS-C medicine (guanylate cyclase-C agonist) | $317.52 for 90 days | See prices |
| Ibsrelatenapanor | IBS-C medicine (NHE3 inhibitor) | Checking prices | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Trulance used for?
Trulance (plecanatide) is a guanylate cyclase-C agonist. According to its FDA label (DailyMed), it is used in adults to treat:
- Chronic idiopathic constipation (CIC), long-lasting constipation with no known cause.
- Irritable bowel syndrome with constipation (IBS-C).
Trulance comes as a 3 mg tablet taken once a day. The label has a boxed warning about the risk of serious dehydration in children: Trulance must not be used in children under 6, should be avoided from age 6 to under 18, and has not been shown safe and effective under 18. It must not be used by people with a known or suspected bowel blockage. Your prescriber decides which medicine is right for you.
Is it safe to order Trulance from Canada?
Many Americans do, but U.S. law and customs rules apply. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, Trulance is sold under the same name by Bausch Health, Canada.
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Sources
- Texas DSHS: 2026 annual wholesale acquisition cost (WAC) report (TRULANCE NDC 65649-0003-30 (30 tablets): $623.81)
- Trulance Savings Card: terms (checked 2026-10-26)
- FDA Orange Book: Trulance (NDA 208745) patents and exclusivity (EOBZIP_2026_09)
- FDA Orange Book: product search
- TRULANCE U.S. prescribing information (DailyMed)
- Bausch Health Patient Assistance Program: eligible medications (Trulance not listed, checked 2026-10-26)
- Health Canada product monograph: TRULANCE (Bausch Health, Canada)
- Linzess: savings and support (AbbVie) (list price $282.48 a month as of January 2026)
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.