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Zyvox Cost, Generic and Savings
- Lowest U.S. online pharmacy price
- Not available
- Lowest international online pharmacy price
- $96.50 per tablet$1,939.95 for one 10-day course, shipping included · brand Zyvox 600 mg, not FDA-approved · ships from United Kingdom
FDA-approved generic linezolid 600 mg from $53 for one 10-day course at U.S. pharmacies
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Quick answerAs of Nov 11, 2026, a 10-day course of generic linezolid 600 mg (20 tablets) costs from $65.40 at licensed pharmacies abroad we compared. The FDA lists brand Zyvox tablets as discontinued, and FDA-approved generic tablets list from $55.00 for 20 in the U.S.
Name check: Zyvox also comes as an IV infusion and an oral suspension (liquid). They aren't priced on this page.
Compare Zyvox prices from licensed online pharmacies
| Pharmacy | Medication | Price | Shipping & delivery | Total | Buy |
|---|---|---|---|---|---|
| Lowest per tabletOnline pharmacy A | Linezolid (India pack, ships from Mauritius)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.600 mg · generic · Filled in MauritiusProduct of India | $31.05for 20 tablets$1.55 per tablet | Fee not publishedDelivery time not stated | $31.05 for one 10-day course= $31.05 for one 10-day course+ shippingincl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy B | Linezolid (India pack, ships from Mauritius)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.600 mg · generic · Filled in MauritiusProduct of India | $41.99for 20 tablets$2.10 per tablet | Fee not publishedDelivery time not stated | $41.99 for one 10-day course= $41.99 for one 10-day course+ shippingincl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy C | Linezolid 600mg Tablets600 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $48for 20 tablets$2.40 per tablet | $5Pharmacy's estimate: 2–8 business days | $53 for one 10-day course= $53 for one 10-day courseincl. $5 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy D | Generic Equivalent To Zyvox 600mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.600 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Zydus Cadila | $50.45for 20 tablets$2.52 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $65.40 for one 10-day course= $65.40 for one 10-day courseincl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | Generic Equivalent To Zyvox 600mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.600 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Zydus Cadila | $53.10for 20 tablets$2.66 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $68.05 for one 10-day course= $68.05 for one 10-day courseincl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy F | Generic Equivalent to Zyvox 600mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.600 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Zydus Cadila | $53.39for 20 tablets$2.67 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $68.34 for one 10-day course= $68.34 for one 10-day courseincl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy G | Linezolid (India pack, ships from Mauritius)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.600 mg · generic · Filled in MauritiusProduct of India | $63.28for 20 tablets$3.16 per tablet | $9.95Delivery time not stated | $73.23 for one 10-day course= $73.23 for one 10-day courseincl. $9.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy H | Generic Zyvox 600mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.600 mg · generic · Filled in IndiaMade for sale in India.Product of India | $65.55per 10 tablets · 2 packs = $131.10$6.56 per tablet | Fee not publishedDelivery time not stated | $131.10 for one 10-day course= $131.10 for one 10-day course+ shippingincl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy I | Linezolid (Linezolid)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.600 mg · generic · Filled in United KingdomProduct of United Kingdom | $321.22for 20 tablets$16.06 per tablet | FreePharmacy's estimate: 2–3 weeks | $321.22 for one 10-day course= $321.22 for one 10-day courseincl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed online pharmacy J | Zyvox 600mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.600 mg · generic · Filled in MauritiusProduct of Mauritius | $397for 40 tablets$9.93 per tablet | FreeDelivery time not stated | $397 for 180 days= $397 for one 10-day courseincl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy K | Zyvox600 mg · brand · Filled in United KingdomMaker listed by pharmacy: Pfizer Inc | $1,930for 20 tablets$96.50 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $1,939.95 for one 10-day course= $1,939.95 for one 10-day courseincl. $9.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy LU.S. shipping limited | Linezolid (Generic)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.600 mg · generic · Filled in IndiaMade for sale in India.Product of India | $52for 20 tablets$2.60 per tablet | $14.95Pharmacy's estimate: 8–14 business days | $66.95 for one 10-day course= $66.95 for one 10-day courseincl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Zyvox from Canada?
Course cost = 20 tablets for one 10-day course, bought as one order of whole packs with one shipping fee. Course cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for one 10-day course; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
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Join to See PharmaciesAlready a member? Sign inZyvox price by strength
| Strength | Lowest brandone 10-day course | Lowest generic abroadone 10-day course, not FDA-approved | Price per tablet |
|---|---|---|---|
| Zyvox 600 mg | $1,939.95 | $65.40 | $96.50 brand · $2.52 generic |
Lowest course cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per tablet is for that lowest pack, before shipping. Prices checked Nov 11, 2026.
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90-day prices from 7 licensed pharmacies abroad shipping to the U.S.: $65.40 to $1,939.95, any strength, shipping included.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Zyvox · Similar drugs · Uses · FAQ
Zyvox (linezolid) 600 mg tablets treat serious bacterial infections, usually for 10 to 28 days. FDA-approved generic linezolid tablets are sold in the U.S.
Other Ways to Pay for Zyvox
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
Checking more than one medicine? Use the free Medicare Drug Cost Check.
Other ways to pay, useful if you have insurance or Medicare:
- TrumpRx.gov: The federal TrumpRx site lists brand Zyvox oral suspension (100 mg per 5 mL, 240 mL bottle) at $122.74 (original price $245.48), checked November 11, 2026. It doesn't list Zyvox tablets. You print or save a coupon and show it at a retail pharmacy. It can't be used with Medicare or Medicaid coverage, and a cash purchase won't count toward a Medicare plan's deductible or the $2,100 yearly cap. With private insurance, ask your plan whether a cash purchase counts toward your deductible. (TrumpRx.gov)
We list these because they may save you money. No one pays us to include them. Prices and eligibility rules change, so confirm before you buy. Checked Nov 11, 2026.
Zyvox cost at a glance
- Brand Zyvox tablets are discontinued in the U.S. The FDA's Drugs@FDA database lists Pfizer's Zyvox 600 mg tablets as discontinued (Drugs@FDA, checked 2026-11-11). Pfizer's FDA drug listing for the tablets ends on February 28, 2027 (FDA drug listing), and the 2026 U.S. list price report has no price for them.
- Generic Zyvox is sold in the U.S. The FDA has approved generic linezolid 600 mg tablets from many companies, rated equivalent to Zyvox (FDA Orange Book). U.S. list prices for a bottle of 20 tablets (a 10-day course) run from $55.00 (Ascend) to $245.42 (Alembic) (Texas DSHS).
- How we count: one 10-day course of 20 tablets. The label's adult dose is 600 mg every 12 hours, for 10 to 14 days for most infections and 14 to 28 days for some. Longer courses need more tablets.
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
- From online pharmacies abroad: $65.40 to $397 for a 10-day course (20 tablets) of generic linezolid 600 mg, shipping included (checked Nov 11, 2026). Packs made for other countries are not FDA-approved.
How much does Zyvox cost in the U.S.?
| If you have | What Zyvox costs | Source |
|---|---|---|
| No insurance (brand list price) | None. The FDA lists brand Zyvox tablets as discontinued in the U.S. FDA-approved generic tablets are sold here; see the next row. | Drugs@FDA |
| No insurance (generic linezolid) | FDA-approved generic linezolid 600 mg tablets are sold in the U.S. List prices for 20 tablets include $55.00 (Ascend), $117.50 (Hetero) and $240.00 (Rising, Chartwell). Ask your pharmacist for the cash price. | Texas DSHS 2026 WAC report |
| Private or employer insurance | Your copay depends on your plan's drug list. Ask your plan how it covers generic linezolid tablets. | FDA Orange Book |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
The FDA lists brand Zyvox 600 mg tablets as discontinued in the U.S. (Drugs@FDA), and the 2026 U.S. list price report has no price for them, so this page shows no U.S. list price for the brand. FDA-approved generic tablets are sold by several U.S. makers. A bottle of 20 tablets, one 10-day course at the label's adult dose, lists at $55.00 to $245.42, depending on the maker (Texas DSHS).
Zyvox cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for generic linezolid depends on your plan's drug list.
| Medicare Part D | What Zyvox costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Zyvox coupons and savings programs
eDrugSearch does not offer its own Zyvox coupons. These programs can help with the cost of Zyvox or generic linezolid:
- TrumpRx.gov coupon: brand Zyvox oral suspension (100 mg per 5 mL, 240 mL bottle) at $122.74 (original price $245.48, checked November 11, 2026), with a coupon you show at a retail pharmacy. Tablets aren't listed. It can't be used with Medicare or Medicaid coverage, and a cash purchase won't count toward a Medicare plan's deductible or the $2,100 yearly cap. With private insurance, ask your plan whether a cash purchase counts toward your deductible. (TrumpRx.gov)
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Zyvox?
Yes. The FDA has approved generic linezolid 600 mg tablets from many companies, including Alkem (Ascend), Hetero (Camber), Alembic, Glenmark, Zydus, Lupin, Rising, Chartwell and Macleods, all rated equivalent to Zyvox. Ascend's has been listed as on the market since December 21, 2015. The FDA lists brand Zyvox tablets as discontinued in the U.S.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 600 mg | Yes | Alkem (Ascend), Hetero (Camber), Alembic, Glenmark, Zydus, Lupin, Rising, Chartwell, Macleods | Dec 21, 2015 |
Outside the U.S.: Online pharmacies abroad may also sell generic linezolid made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: FDA Orange Book: linezolid products. As of Nov 11, 2026.
Compare Zyvox with similar drugs
Other antibiotics people often look up, such as Vancocin (vancomycin) and Dificid (fidaxomicin). They treat different infections than Zyvox. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Vancocinvancomycin capsules | Antibiotic taken by mouth for gut infections (glycopeptide) | $249.31 for one 10-day course | See prices |
| Dificidfidaxomicin | Antibiotic for C. diff diarrhea (macrolide) | $2,808.95 for one 10-day course | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Zyvox used for?
Zyvox (linezolid) is an antibiotic in the oxazolidinone family. According to its FDA label (DailyMed), it treats these infections when they're caused by certain bacteria (Gram-positive bacteria):
- Pneumonia caught in a hospital or in the community.
- Complicated skin infections, including diabetic foot infections without bone infection.
- Uncomplicated skin infections.
- Infections with vancomycin-resistant Enterococcus faecium (VRE).
Zyvox tablets come in one strength, 600 mg. For adults, the label dose is 600 mg every 12 hours, usually for 10 to 14 days, or 14 to 28 days for some infections. Zyvox has no boxed warning. It must not be used by people allergic to linezolid or by people taking an MAO inhibitor (a type of antidepressant) or who took one in the past two weeks. Your prescriber decides which medicine is right for you.
Is it safe to order Zyvox from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Zyvox, compare the U.S. price of FDA-approved generic linezolid before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada the brand is called Zyvoxam, and Health Canada lists Pfizer's Zyvoxam 600 mg tablets as cancelled since July 2020 (Health Canada).
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much does Zyvox cost without insurance?
Brand Zyvox tablets are listed as discontinued in the U.S., and the 2026 U.S. list price report has no price for them. FDA-approved generic linezolid is sold here: a bottle of 20 tablets of 600 mg lists at $55.00 to $245.42, depending on the maker. Licensed pharmacies abroad charged from $65.40 for a 10-day course of generic linezolid in our latest check (Nov 11, 2026).
Is there a generic Zyvox?
Yes. The FDA has approved generic linezolid 600 mg tablets from many companies, rated equivalent to Zyvox. Generics have been on the U.S. market since December 2015. The generic name is linezolid.
What is the generic name for Zyvox?
Linezolid. Generic linezolid 600 mg tablets are FDA-approved and rated equivalent to Zyvox. Ask your pharmacist whether a generic can fill your prescription.
Was Zyvox discontinued?
The FDA's Drugs@FDA database lists brand Zyvox 600 mg tablets as discontinued in the U.S., and Pfizer's drug listing for them ends February 28, 2027. Zyvox IV infusion and oral suspension are still listed. Generic linezolid tablets are sold in the U.S.
How many linezolid tablets are in a course?
At the label's adult dose of 600 mg every 12 hours, that's 2 tablets a day. A 10-day course is 20 tablets, a 14-day course is 28, and a 28-day course is 56. Your prescriber decides how long you take it.
How much does Zyvox cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. Ask your plan how it covers generic linezolid. People with limited income can apply for Extra Help.
Sources
- Drugs@FDA: Zyvox tablets (NDA 021130) (600 mg tablets Discontinued; 400 mg discontinued, not for safety or effectiveness reasons)
- FDA NDC Directory: Zyvox 600 mg tablets (NDC 0009-5138) (bottle of 20, marketing end date February 28, 2027)
- Texas DSHS: 2026 annual WAC report (generic linezolid 600 mg x 20: Ascend $55.00, Hetero $117.50, Rising $240.00, Chartwell $240.00, Alembic $245.42; no Zyvox tablet row (Pfizer rows are oral suspension))
- ZYVOX U.S. prescribing information (DailyMed) (Pfizer, label version 73, effective November 3, 2026)
- FDA Orange Book: linezolid products
- FDA NDC Directory: Ascend linezolid 600 mg (NDC 67877-419) (ANDA 205517 (Alkem), marketing start December 21, 2015)
- Health Canada Drug Product Database: Zyvoxam (Pfizer Canada; 600 mg tablet (DIN 02243684) Cancelled Post Market July 31, 2020; IV solution and oral suspension Marketed)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.