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Dificid Price (fidaxomicin)
As of Nov 11, 2026, brand Dificid 200 mg costs from $2,808.95 for one 10-day course at licensed pharmacies abroad (ships from Canada; packs made for other countries are not FDA-approved), vs. $5,205 at the U.S. list price.
- U.S. list price
- $5,205 for one 10-day courseThe maker's price for brand Dificid before discounts · Source: Texas DSHS 2026 WAC report
- Lowest international online pharmacy price
- $139.95 per tablet$2,808.95 for one 10-day course, shipping included · brand Dificid 200 mg, not FDA-approved · ships from Canada
FDA-approved generic fidaxomicin 200 mg from $1,416.84 for one 10-day course at U.S. pharmacies · See fidaxomicin prices
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Compare Dificid prices from licensed pharmacies
For comparison U.S. pharmacy list price: $5,205 for one 10-day course ($260.25 per tablet), brand Dificid before insurance. The prices below are from U.S. pharmacies that publish cash prices and from licensed online pharmacies outside the U.S.
| Pharmacy | Medication | Price | Shipping & delivery | Total | Buy |
|---|---|---|---|---|---|
| Lowest per tabletLicensed U.S. pharmacy A | Fidaxomicin200 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Oct 29, 2026 | $1,411.59for 20 tablets$70.58 per tablet | $5.25Delivery time not stated | $1,416.84 for one 10-day course= $1,416.84 for one 10-day courseSave 73%incl. $5.25 shippingChecked Oct 29 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy B | Dificid 200mg Tablet200 mg · brand · Filled in CanadaMaker listed by pharmacy: Merck Sharp & Dohme | $2,799for 20 tablets$139.95 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $2,808.95 for one 10-day course= $2,808.95 for one 10-day courseSave 46%incl. $9.95 shippingChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed Canadian pharmacy C | Dificid200 mg · brand · Filled in CanadaMaker listed by pharmacy: MERCK CANADA INC | $3,431.92for 20 tablets$171.60 per tablet | $9.95Pharmacy's estimate: 3–6 weeks | $3,441.87 for one 10-day course= $3,441.87 for one 10-day courseSave 34%incl. $9.95 shippingChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy D | Fidaxomicin, 200 MG Tablet (Prime member price)200 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $6,746.17for 30 tablets$224.87 per tablet | FreePharmacy's estimate: Usually next day | $6,746.17 for 135 days= $6,746.17 for one 10-day courseincl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy D | Fidaxomicin, 200 MG Tablet (price without insurance)200 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $7,120.50for 30 tablets$237.35 per tablet | Fee not publishedPharmacy's estimate: Usually next day | $7,120.50 for 135 days= $7,120.50 for one 10-day course+ shippingincl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Dificid from Canada?
Course cost = 20 tablets for one 10-day course, bought as one order of whole packs with one shipping fee. Course cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for one 10-day course; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
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90-day prices from 2 licensed pharmacies abroad shipping to the U.S.: $2,808.95 to $3,441.87, any strength, shipping included.
Jump to: Medicare · Maker savings · Generic Dificid · Similar drugs · Uses · FAQ
Dificid (fidaxomicin) 200 mg tablets for C. diff diarrhea, usually one 10-day course of 20 tablets. FDA-approved generic fidaxomicin is sold in the U.S.
Dificid price by strength
| Strength | Lowest brandone 10-day course | Price per tablet |
|---|---|---|
| Dificid 200 mg | $2,808.95 | $139.95 |
Lowest course cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per tablet is for that lowest pack, before shipping. Prices checked Nov 11, 2026.
Cheapest ways to get Dificid 200 mg
The cheapest ways we found to get brand Dificid 200 mg (prices checked Nov 11, 2026). The lowest course cost is shaded green.
| Way to buy | Cost | Details |
|---|---|---|
| Licensed online pharmacy abroad | $2,808.95 for one 10-day course | Brand Dificid 200 mg, ships from Canada, not FDA-approved (made for another country). Shipping included, checked Nov 11, 2026. See all prices |
| U.S. list price | $5,205 for one 10-day course | Brand Dificid before insurance. Pharmacies may charge more. |
| Medicare Part D | Depends on your plan | Your plan’s drug list and coverage phase set your cost. Medicare costs |
Costs abroad and at U.S. pharmacies are for one order closest to 90 days, shipping included, from the price table above. Programs set their own rules, so check the terms before you count on one.
How much does Dificid cost without insurance?
Without insurance, Dificid costs $1,735 for a 30-day supply at the U.S. list price, or about $5,205 for one 10-day course. Licensed pharmacies abroad charged from $2,808.95 for one 10-day course of brand Dificid 200 mg in our latest check (Nov 11, 2026), shipping included. Merck patient assistance program: Free Dificid for people with no prescription coverage whose household income is within the program's limits. Call 1-800-727-5400 (Merck Helps).
Dificid cost with Medicare
In 2026, a Medicare drug plan (Part D) can charge a deductible of up to $615, and once you've spent $2,100 out of pocket on covered drugs, you pay nothing more for covered drugs that year ($2,400 in 2027) (Medicare.gov). What you pay for Dificid depends on your plan's drug list and your coverage phase. If your income is limited, Extra Help lowers drug costs: in 2026 you pay no more than $5.10 for a generic and $12.65 for a brand-name drug, with income under $23,940 ($32,460 for a married couple) and resources under $18,090 ($36,100 for a couple) (CMS). The free Medicare Prescription Payment Plan spreads costs into monthly payments, but it doesn't lower the total.
| Medicare Part D | What Dificid costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Dificid cost with insurance
With private or employer insurance, what you pay for Dificid depends on your plan's drug list, deductible and copay. Your copay depends on your plan and whether you have met your deductible (Texas DSHS 2026 WAC report).
Medicaid: Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office (Medicaid.gov).
Dificid patient assistance program
Not that we could find. Merck Patient Assistance Program is Merck's free-medicine program, but Dificid wasn't on its list of medicines when we checked on 2026-10-29 (official page). If you have Medicare and a limited income, Medicare Extra Help can lower what you pay.
Is there a generic Dificid?
Yes. The FDA approved generic fidaxomicin 200 mg tablets from Teva (Actavis), Torrent, Apotex, Sandoz and Hikma, all rated equivalent to Dificid. Teva's generic has been listed for sale in the U.S. since July 15, 2025; the others were listed between January and October 2026. See generic Dificid (fidaxomicin) prices.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 200 mg | Yes | Teva (Actavis), Torrent, Apotex, Sandoz, Hikma | Jul 15, 2025 |
Outside the U.S.: Online pharmacies abroad may sell generic fidaxomicin made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: FDA Orange Book: fidaxomicin products. As of Oct 26, 2026.
Dificid FAQ
How much is Dificid without insurance?
The U.S. list price is $5,205 for 20 tablets of brand Dificid 200 mg, one 10-day course (the maker's 2026 price before discounts, as reported to the Texas Department of State Health Services). Licensed pharmacies abroad charged from $2,808.95 for a 10-day course of brand Dificid in our latest check (Nov 11, 2026). FDA-approved generic fidaxomicin is also sold in the U.S.; Teva's was listed at $4,497.12 for 20 tablets in the same filing.
How much does Dificid cost with Medicare?
It depends on your Part D plan. In 2026, plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs that year. The Medicare Prescription Payment Plan can spread those costs into monthly payments.
Is there a generic Dificid?
Yes. The FDA approved generic fidaxomicin 200 mg tablets from Teva, Torrent, Apotex, Sandoz and Hikma, all rated equivalent to Dificid. Teva's generic has been listed for sale in the U.S. since July 15, 2025. Ask your pharmacist whether a generic can fill your prescription. See generic Dificid (fidaxomicin) prices.
How much does a course of fidaxomicin cost?
A usual adult course is 20 tablets (200 mg twice a day for 10 days). The U.S. list price is $5,205 for brand Dificid and $4,497.12 for Teva's generic fidaxomicin (the makers' 2026 prices before discounts, as reported to the Texas Department of State Health Services). What you pay depends on your insurance and pharmacy.
Why is Dificid so expensive?
Dificid is a brand antibiotic first approved in the U.S. in 2011, and its U.S. list price is $5,205 for one 10-day course (the maker's 2026 price before discounts, as reported to the Texas Department of State Health Services). Generic fidaxomicin has been sold in the U.S. since July 2025; Teva's was listed at $4,497.12 for the same 20 tablets.
What is Dificid called in other countries?
In Canada it is sold as Dificid by Merck Canada. In the U.K. and the European Union it is sold as Dificlir. The active ingredient, fidaxomicin, is the same.
Does Dificid come as a liquid?
Yes. Dificid is also sold in the U.S. as granules for oral suspension (200 mg per 5 mL after mixing), mainly for children, dosed by weight. Once mixed, it is kept in the refrigerator and thrown away after 12 days. This page prices the 200 mg tablets.
Brand vs. generic: cost for one 10-day course
| Option | 90 days |
|---|---|
| Generic fidaxomicin 200 mg, U.S. pharmacy cash priceLowest U.S. pharmacy price we found, checked Oct 29, 2026 | $1,416.84 |
| Brand Dificid 200 mg from licensed pharmacies abroadLowest price we found, shipping included, checked Nov 11, 2026 | $2,808.95 |
| Brand Dificid, U.S. list priceBefore insurance; pharmacies may charge more | $5,205 |
Lowest in this comparison: Generic fidaxomicin 200 mg, U.S. pharmacy cash price.
90 days = 20 tablets of 200 mg. Generic sold abroad is not FDA-approved and is not in this box. Your price with insurance or Medicare depends on your plan.
Savings programs from the maker
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
eDrugSearch does not offer its own Dificid coupons. We found no Merck copay card or cash price for Dificid on Merck's sites in our latest check. These are the programs we could verify:
- Merck Patient Assistance Program: free Dificid for U.S. residents with no insurance or other prescription coverage (Medicare counts as coverage) and household income within the program's limits. Merck's Dificid tablets page doesn't list the income limits; call to check. Hardship exceptions may be possible. Call 1-800-727-5400. (Merck Helps)
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make a large one-time cost easier to manage. (Medicare.gov)
- Costco Pharmacy member prices: Costco publishes member prices for many prescriptions, for people with a Costco membership. Non-members can also use Costco pharmacies and pay the regular cash price. Member prices can't be used with insurance, Medicare or Medicaid claims. (Costco Pharmacy)
- Amazon Pharmacy Prime and RxPass: Amazon Pharmacy offers Prime members discounts on many prescriptions, and RxPass, for Prime members, covers a set list of generics for a flat monthly fee. Prime is not required to use Amazon Pharmacy. Prime savings have limits for people with Medicare, Medicaid or Tricare, and RxPass is not open to people with Medicaid or CHIP. (Amazon Pharmacy)
- Discount cards: Discount cards (for example GoodRx or SingleCare) may lower the price at local pharmacies; prices vary by pharmacy and ZIP code.
Compare Dificid with similar drugs
Xifaxan (rifaximin) is another antibiotic that acts mainly in the gut. It is FDA-approved for different conditions than Dificid. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Xifaxanrifaximin | Gut-acting antibiotic (rifamycin) | $75.40 for one 10-day course | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Dificid used for?
Dificid (fidaxomicin) is a macrolide antibiotic. According to its FDA label (prescribing information), it is used:
- To treat diarrhea caused by Clostridioides difficile (C. diff) in adults and children 6 months and older.
The label's usual adult dose is one 200 mg tablet twice a day for 10 days (20 tablets). Children who weigh at least 12.5 kg and can swallow tablets take the same tablet dose; Dificid also comes as an oral suspension (liquid) dosed by weight, which is not priced on this page. The label says Dificid should be used only for infections proven or strongly suspected to be caused by C. diff, because it is not expected to work for other infections. Dificid has no boxed warning. Your prescriber decides which medicine is right for you.
Is it safe to order Dificid from Canada?
Many Americans do, but U.S. law and customs rules apply. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, Dificid is sold under the same name by Merck Canada; in the U.K. and Europe it is sold as Dificlir.
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Sources
- Texas DSHS: 2026 annual WAC report (Dificid 20 tablets (NDC 52015-0080-01) $5,205; Teva fidaxomicin 20 tablets (NDC 00480-2596-34) $4,497.12)
- DIFICID U.S. prescribing information (Merck) (revised 06/2022)
- FDA Orange Book: fidaxomicin products (EOBZIP_2026_09)
- FDA NDC Directory: fidaxomicin (marketing start dates, data of 2026-10-23)
- Merck Patient Assistance Program: Dificid tablets (income limits not listed on the page; checked 2026-10-29)
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicaid.gov: cost sharing
- FDA: personal importation
- Merck Canada: Dificid product monograph
- European Medicines Agency: Dificlir
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.