Rexulti Cost (brexpiprazole)

Rexulti price by strength

Cheapest ways to get Rexulti 2 mg

The cheapest ways we found to get brand Rexulti 2 mg (prices checked Nov 11, 2026). The lowest 90-day cost is shaded green.

Costs abroad and at U.S. pharmacies are for one order closest to 90 days, shipping included, from the price table above. Programs set their own rules, so check the terms before you count on one.

How much does Rexulti cost without insurance?

Without insurance, Rexulti costs $1,555.86 for a 30-day supply at the U.S. list price, or about $4,667.58 for 90 days. Licensed pharmacies abroad charged from $384.95 for 90 days of brand Rexulti 2 mg in our latest check (Nov 11, 2026), shipping included. Otsuka patient assistance foundation: Help for uninsured and underinsured people who meet the foundation's eligibility criteria. Call 855-727-6274 (Otsuka).

Rexulti cost with Medicare

In 2026, a Medicare drug plan (Part D) can charge a deductible of up to $615, and once you've spent $2,100 out of pocket on covered drugs, you pay nothing more for covered drugs that year ($2,400 in 2027) (Medicare.gov). What you pay for Rexulti depends on your plan's drug list and your coverage phase. If your income is limited, Extra Help lowers drug costs: in 2026 you pay no more than $5.10 for a generic and $12.65 for a brand-name drug, with income under $23,940 ($32,460 for a married couple) and resources under $18,090 ($36,100 for a couple) (CMS). The free Medicare Prescription Payment Plan spreads costs into monthly payments, but it doesn't lower the total.

Rexulti cost with insurance

With private or employer insurance, what you pay for Rexulti depends on your plan's drug list, deductible and copay. As little as $0 with the Rexulti copay program, up to $8,180 a year (13 uses per calendar year) (Otsuka).

Medicaid: Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office (Medicaid.gov).

Rexulti patient assistance program

Otsuka runs Otsuka Patient Assistance Foundation (OPAF). Who qualifies: OPAF helps underinsured and uninsured patients who have been prescribed Otsuka medicines and meet its eligibility criteria. We couldn't confirm on the program's own pages that Rexulti is on its current list (checked 2026-10-29), so call 855-727-6274 to ask before you apply.

Rexulti FAQ

Savings programs from the maker

eDrugSearch does not offer its own Rexulti coupons. Otsuka offers no cash-price program for Rexulti; it says people without coverage can expect to pay the list price plus pharmacy charges. These are the programs we could verify:

• Rexulti Savings Card: for people with commercial (private or employer) insurance. Eligible patients may pay as little as $0 for Rexulti, including 90-day prescriptions, up to $8,180 a year and 13 uses per calendar year. It can also pay up to $100 per 30-day supply of an eligible generic antidepressant. Not for Medicare Part D, Medicaid, Medigap, VA or other government programs. U.S. and Puerto Rico only. Call 1-844-415-0674 or text SAVE to 96747. (Rexulti savings)
• Otsuka Patient Assistance Foundation (OPAF): a foundation that helps uninsured and underinsured people who have been prescribed Otsuka medicines. It has its own eligibility criteria, and approval isn't guaranteed. Call 855-727-6274 (Monday to Friday, 8 AM to 6 PM Eastern). (Otsuka patient assistance)
• Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
• Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)

Compare Rexulti with similar drugs

Other mental health medicines people often compare with Rexulti. Your prescriber decides which medicine is right for you. Prices are for each drug's lowest-priced strength.

Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.

What is Rexulti used for?

Rexulti (brexpiprazole) is an atypical antipsychotic. According to its FDA label (DailyMed), it is used for:

• Major depressive disorder (MDD) in adults, taken together with an antidepressant.
• Schizophrenia in adults and children 13 years and older.
• Agitation associated with dementia due to Alzheimer's disease. It is not for as-needed use.

Rexulti comes as 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg and 4 mg tablets taken once a day. Its label has a boxed warning: older adults with dementia-related psychosis who take antipsychotic medicines have a higher risk of death (Rexulti is not approved for dementia-related psychosis unless it is agitation from Alzheimer's dementia), and antidepressants raised the risk of suicidal thoughts and behaviors in children and young adults in short-term studies. Your prescriber decides which medicine is right for you.