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Caplyta Price (lumateperone)
Caplyta's U.S. list price is $5,129.82 for 90 days. In our latest check (Nov 11, 2026), none of the licensed pharmacies abroad we list sold brand Caplyta 42 mg with a named maker, so the U.S. options below are the ones we can confirm.
- Lowest U.S. online pharmacy price
- $61.06 per capsule$5,495.55 for 90 days (90 capsules), shipping included · FDA-approved brand Caplyta 42 mg · ships within the U.S.
- Lowest international online pharmacy price
- Not available
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Compare Caplyta prices from licensed pharmacies
For comparison U.S. pharmacy list price: $5,129.82 for 90 days ($57.00 per capsule), brand Caplyta before insurance. The prices below are from U.S. pharmacies that publish cash prices and from licensed online pharmacies outside the U.S.
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per capsuleLicensed U.S. pharmacy A | Caplyta, 42 MG Capsule (Prime member price)42 mg · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $1,831.85per 30 capsules · 3 packs = $5,495.55$61.06 per capsule | FreePharmacy's estimate: Usually next day | $5,495.55 for 90 days= $5,495.55 for 90 daysincl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleLicensed U.S. pharmacy A | Caplyta, 42 MG Capsule (price without insurance)42 mg · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $2,161.20per 30 capsules · 3 packs = $6,483.60$72.04 per capsule | Fee not publishedPharmacy's estimate: Usually next day | $6,483.60 for 90 days= $6,483.60 for 90 days+ shippingincl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Caplyta from Canada?
90-day cost = 90 capsules at the usual dose of 1 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
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Jump to: Medicare · Maker savings · Generic Caplyta · Similar drugs · Uses · FAQ
Caplyta (lumateperone) for schizophrenia, bipolar depression and, with an antidepressant, major depressive disorder. 10.5, 21 and 42 mg capsules.
Cheapest ways to get Caplyta 42 mg
The cheapest ways we found to get brand Caplyta 42 mg (prices checked Nov 11, 2026). The lowest 90-day cost is shaded green.
| Way to buy | Cost | Details |
|---|---|---|
| U.S. pharmacy cash price | $5,495.55 for 90 days | FDA-approved brand Caplyta 42 mg, ships within the U.S. (no customs). Shipping included, checked Nov 11, 2026. See all prices |
| U.S. list price | $5,129.82 for 90 days | Brand Caplyta before insurance. Pharmacies may charge more. |
| Medicare Part D | Depends on your plan | Your plan’s drug list and coverage phase set your cost. Medicare costs |
Costs abroad and at U.S. pharmacies are for one order closest to 90 days, shipping included, from the price table above. Programs set their own rules, so check the terms before you count on one.
How much does Caplyta cost without insurance?
Without insurance, Caplyta costs $1,709.94 for a 30-day supply at the U.S. list price, or about $5,129.82 for 90 days. Patient assistance: The maker's withMe Patient Assistance program may help eligible patients. Call 1-833-742-0791 (withMe Patient Assistance).
Caplyta cost with Medicare
In 2026, a Medicare drug plan (Part D) can charge a deductible of up to $615, and once you've spent $2,100 out of pocket on covered drugs, you pay nothing more for covered drugs that year ($2,400 in 2027) (Medicare.gov). What you pay for Caplyta depends on your plan's drug list and your coverage phase. If your income is limited, Extra Help lowers drug costs: in 2026 you pay no more than $5.10 for a generic and $12.65 for a brand-name drug, with income under $23,940 ($32,460 for a married couple) and resources under $18,090 ($36,100 for a couple) (CMS). The free Medicare Prescription Payment Plan spreads costs into monthly payments, but it doesn't lower the total.
| Medicare Part D | What Caplyta costs | Source |
|---|---|---|
| Part D deductible (2026) | Up to $615 a year, depending on your plan | Medicare.gov |
| Part D out-of-pocket cap (2026) | $2,100 a year for covered drugs | Medicare.gov |
| Negotiated price | None: Caplyta is not on the 2026, 2027 or 2028 lists | CMS |
| Limited income | Extra Help can lower what you pay for prescriptions | Social Security |
Caplyta cost with insurance
With private or employer insurance, what you pay for Caplyta depends on your plan's drug list, deductible and copay. As little as $0 for a 30-, 60- or 90-day prescription with the CAPLYTA withMe Savings Program. An annual maximum applies (Caplyta (maker)).
Medicaid: Depends on your state's plan. The maker's copay program can't be used (Caplyta (maker)).
Caplyta patient assistance program
Intra-Cellular Therapies, part of Johnson & Johnson runs Johnson & Johnson Patient Assistance Program. Who qualifies: People who are uninsured or have commercial, employer or government coverage, live in the U.S. or a U.S. territory, are treated as outpatients and meet income limits. Medicare Part D members must show they aren't eligible for Extra Help and spend more than 4% of gross yearly household income on prescriptions. Eligible people may get the medicine free for up to one year. We couldn't confirm on the program's own pages that Caplyta is on its current list (checked 2026-10-29), so call 833-742-0791 to ask before you apply.
Is there a generic Caplyta?
No. No generic Caplyta is sold in the U.S. Under a January 2025 patent settlement, Sandoz may start selling a generic on July 1, 2040, or earlier in certain circumstances. The generic name for Caplyta is lumateperone.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 10.5 mg | No | — | |
| 21 mg | No | — | |
| 42 mg | No | — |
Outside the U.S.: One pharmacy abroad listed a generic lumateperone 42 mg capsule from India without naming the maker. Generics bought abroad are not FDA-approved.
Source: Intra-Cellular Therapies: patent settlement with Sandoz (SEC filing). As of Oct 25, 2026.
Caplyta FAQ
Does Caplyta have a generic yet?
No. No generic Caplyta is sold in the U.S. Under a patent settlement, Sandoz may start selling a generic on July 1, 2040, or earlier in certain circumstances. The generic name is lumateperone.
How much is Caplyta with insurance?
With commercial or private insurance, the CAPLYTA withMe Savings Program lets eligible patients pay as little as $0 for a 30-, 60- or 90-day prescription, up to an annual maximum. It can't be used with Medicare, Medicaid, TRICARE, VA or other government programs. eDrugSearch does not offer its own Caplyta offers.
How much does a 30-day supply of Caplyta cost?
The U.S. list price is $1,709.94 for 30 capsules of any strength, 10.5 mg, 21 mg or 42 mg (the maker's 2026 price before discounts, as reported to the Texas Department of State Health Services). Pharmacies may charge more. The maker's copay program is only for people with commercial or private insurance.
How much does Caplyta cost with Medicare?
It depends on your Part D plan. In 2026, the Part D deductible is up to $615 and out-of-pocket costs for covered drugs are capped at $2,100. Caplyta is not one of the drugs Medicare has selected for price negotiation so far. People with limited income can apply for Extra Help.
Is there a patient assistance program for Caplyta?
Caplyta's maker runs a patient assistance program through withMe Patient Assistance. Call 1-833-742-0791 to ask whether Caplyta and your situation qualify. People with Medicare and limited income can also apply for Extra Help.
Who makes Caplyta?
Caplyta is made by Intra-Cellular Therapies, which has been part of Johnson & Johnson since April 2025.
Can I buy Caplyta from Canada or other countries?
None of the licensed online pharmacies we list sold brand Caplyta with a named maker when we checked (Nov 11, 2026). One listed a generic lumateperone 42 mg capsule from India but didn't name the maker; it is shown in the price table under "Maker not named by the pharmacy" and is not FDA-approved. Any purchase from abroad needs a prescription, and U.S. import rules apply.
What medication is similar to Caplyta?
Other atypical antipsychotics people often look up with Caplyta include Vraylar, Rexulti, Latuda and Abilify. Your prescriber decides which medicine is right for you.
Savings programs from the maker
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
eDrugSearch does not offer its own Caplyta coupons. These are the real savings programs, run by the drug's maker and by Medicare:
- CAPLYTA withMe Savings Program: for adults 18 and older with commercial or private insurance, including Health Insurance Marketplace plans. Eligible patients may pay as little as $0 for a 30-, 60- or 90-day prescription. An annual maximum benefit applies. Not for Medicare, Medicaid, TRICARE, VA or other government programs. Text CAPLYTA to 26789 for a digital card. (Caplyta savings)
- withMe Patient Assistance (maker's patient assistance program): the maker's patient assistance program; Intra-Cellular Therapies' patient assistance page now leads to it. It may help eligible patients who can't afford their medicine. Call 1-833-742-0791 to ask whether Caplyta and your situation qualify. (withMe Patient Assistance)
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Compare Caplyta with similar drugs
Other medicines in the same broad group (atypical antipsychotics) that people often look up with Caplyta. Prices are for each drug's lowest-priced strength. Your prescriber decides which medicine is right for you.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Vraylarcariprazine | Mental health medicine (atypical antipsychotic) | $65.92 for 90 days | See prices |
| Rexultibrexpiprazole | Mental health medicine (atypical antipsychotic) | $384.95 for 90 days | See prices |
| Abilifyaripiprazole | Mental health medicine (atypical antipsychotic) | $32.91 for 90 days | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Caplyta used for?
Caplyta (lumateperone) is an atypical antipsychotic. According to its FDA label (DailyMed), it is used in adults to treat:
- Schizophrenia.
- Depressive episodes of bipolar I or bipolar II disorder (bipolar depression), alone or together with lithium or valproate.
- Major depressive disorder (MDD), as an add-on to an antidepressant.
Caplyta comes as 10.5 mg, 21 mg and 42 mg capsules. Its label has a boxed warning about a higher risk of death in older adults with dementia-related psychosis, and about suicidal thoughts and behaviors. It is not approved for dementia-related psychosis or for children. Your prescriber decides which medicine is right for you.
Is it safe to order Caplyta from Canada?
None of the licensed pharmacies we list sold brand Caplyta with a named maker when we checked. One listed a generic lumateperone 42 mg capsule from India without naming the maker (see the price table); generics bought abroad are not FDA-approved. If you buy from abroad, U.S. law and customs rules apply. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). New U.S. Customs rules for mailed orders start January 20, 2027.
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Sources
- Texas DSHS: 2026 annual wholesale acquisition cost (WAC) report (CAPLYTA NDCs 72060-110-40, 72060-121-40, 72060-142-40: $1,709.94)
- Caplyta: cost and savings
- CAPLYTA withMe Savings Program terms (PDF)
- CAPLYTA U.S. prescribing information (DailyMed)
- CAPLYTA prescribing information (FDA, revised April 2026)
- FDA Orange Book: CAPLYTA patents and exclusivity (NDA 209500)
- Intra-Cellular Therapies: patent settlement with Sandoz (SEC filing) (January 8, 2025)
- Johnson & Johnson: Intra-Cellular Therapies acquisition closed (April 2, 2025)
- CMS: drugs selected for Medicare price negotiation (2028)
- withMe Patient Assistance (maker) (1-833-742-0791; checked October 25, 2026)
- Medicare.gov: Part D costs (2026 deductible and out-of-pocket cap)
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.