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Pifeltro Price and Savings
- U.S. list price
- $5,519.70 for 90 days (90 tablets)The maker's price for brand Pifeltro before discounts · Source: Texas DSHS 2026 WAC report
- Lowest international online pharmacy price
- $21.50 per tablet$1,944.95 for 90 days (90 tablets), shipping included · brand Pifeltro 100 mg, not FDA-approved · ships from Canada
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Quick answerAs of Nov 12, 2026, brand Pifeltro 100 mg costs from $1,944.95 for 90 days (90 tablets) at online pharmacies abroad we compared, vs. $5,519.70 at the U.S. list price ($1,839.90 for 30 tablets). No generic is sold in the U.S.
Name check: Pifeltro is doravirine alone, taken with other HIV medicines. Delstrigo combines doravirine with two more medicines in one tablet and has its own page.
Compare Pifeltro prices from licensed online pharmacies
For comparison U.S. pharmacy list price: $5,519.70 for 90 days ($61.33 per tablet), brand Pifeltro before insurance. The prices below are from licensed online pharmacies outside the U.S.
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per tabletOnline pharmacy A | Pifeltro100 mg · brand · Filled in CanadaMaker listed by pharmacy: Merck Sharp & Dohme | $645per 30 tablets · 3 packs = $1,935$21.50 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $1,944.95 for 90 days= $1,944.95 for 90 daysSave 65%incl. $9.95 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy B | PIFELTRO100 mg · brand · Filled in CANADAMade for sale in CANADA.Product of Canada | $869.82per 30 tablets · 3 packs = $2,609.46$28.99 per tablet | FreeDelivery time not stated | $2,609.46 for 90 days= $2,609.46 for 90 daysSave 53%incl. $0 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | PIFELTRO100 mg · brand · Filled in CANADAMade for sale in CANADA.Product of Canada | $872.21per 30 tablets · 3 packs = $2,616.63$29.07 per tablet | FreeDelivery time not stated | $2,616.63 for 90 days= $2,616.63 for 90 daysSave 53%incl. $0 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Pifeltro from Canada?
90-day cost = 90 tablets at the usual dose of 1 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 12, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout.
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Join to See PharmaciesAlready a member? Sign inPifeltro price by strength
| Strength | Lowest brand90 days | Price per tablet |
|---|---|---|
| Pifeltro 100 mg | $1,944.95 | $21.50 |
Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per tablet is for that lowest pack, before shipping. Prices checked Nov 12, 2026.
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90-day prices from 3 licensed pharmacies shipping to the U.S.: $1,944.95 to $2,616.63, any strength, shipping included.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Pifeltro · Similar drugs · Uses · FAQ
Pifeltro (doravirine) 100 mg once-a-day tablets, used with other HIV-1 medicines. No generic Pifeltro is sold in the U.S.
Pifeltro cost at a glance
- U.S. list price: $1,839.90 for a bottle of 30 Pifeltro 100 mg tablets, a 30-day supply, or $5,519.70 for 90 days. That's Merck's wholesale price before discounts (Texas DSHS).
- No U.S. generic. Drugs@FDA lists no generic doravirine, so Merck's Pifeltro (approved August 30, 2018) is the only version sold here (Drugs@FDA).
- How we count: 1 tablet a day, the label's usual dose, so 90 days is 90 tablets.
- From online pharmacies abroad: $1,944.95 to $2,616.63 for 90 days of brand Pifeltro 100 mg, shipping included (checked Nov 12, 2026). Packs made for other countries are not FDA-approved.
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
How much does Pifeltro cost in the U.S.?
| If you have | What Pifeltro costs | Source |
|---|---|---|
| No insurance (brand list price) | $1,839.90 for 30 tablets of Pifeltro 100 mg. Pharmacies may charge more. | Texas DSHS 2026 WAC report |
| Private or employer insurance | Your copay depends on your plan's drug list. Ask your plan or pharmacist what you'd pay for brand Pifeltro. | FDA Orange Book |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Brand Pifeltro lists at $1,839.90 for a bottle of 30 tablets in the U.S., a 30-day supply (Texas DSHS). That's the maker's wholesale price before discounts; what a pharmacy charges can differ. No generic is sold in the U.S.
Pifeltro cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Pifeltro depends on your plan's drug list.
| Medicare Part D | What Pifeltro costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Pifeltro coupons and savings programs
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
Checking more than one medicine? Use the free Medicare Drug Cost Check.
eDrugSearch does not offer its own Pifeltro coupons. eDrugSearch has no coupons of its own. These programs can help:
- AIDS Drug Assistance Program (ADAP): run by each state and territory under the federal Ryan White HIV/AIDS Program. It helps low-income people with HIV who have limited or no health insurance get FDA-approved HIV medicines, and can help pay for health insurance. (HRSA: ADAP)
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Pifeltro?
No. No generic Pifeltro is sold in the U.S. Drugs@FDA lists no generic doravirine.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 100 mg | No | — |
Outside the U.S.: Online pharmacies abroad may sell generic doravirine made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: Drugs@FDA: Pifeltro (NDA 210806). As of Nov 14, 2026.
Compare Pifeltro with similar drugs
Other HIV medicines with price pages here: Delstrigo contains doravirine plus two more medicines, Edurant is another NNRTI, and Isentress and Tivicay work differently. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Delstrigodoravirine, lamivudine and tenofovir disoproxil fumarate | HIV medicine (complete one-tablet regimen) | $3,003.46 for 90 days | See prices |
| Edurantrilpivirine | HIV medicine (NNRTI) | $1,049.05 for 90 days | See prices |
| Isentressraltegravir | HIV medicine (integrase inhibitor) | $710.75 for 90 days | See prices |
| Tivicaydolutegravir | HIV medicine (integrase inhibitor) | $1,381.29 for 90 days | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Pifeltro used for?
Pifeltro (doravirine) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), an HIV medicine. According to its FDA label (DailyMed), it is used:
- Together with other HIV medicines, to treat HIV-1 in adults and children who weigh at least 35 kg (77 lb): for people starting HIV treatment for the first time, or to replace a current regimen in people whose virus is already well controlled and who meet the label's conditions.
The label's dose is one 100 mg tablet once a day, with or without food; with the tuberculosis medicine rifabutin, it's one tablet twice a day. Pifeltro has no boxed warning. Pifeltro doesn't cure HIV. Your prescriber decides which medicine is right for you.
Is it safe to order Pifeltro from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Pifeltro, check your insurance and your state's ADAP first; HIV medicines need a steady supply, so plan around shipping times. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. Health Canada lists Pifeltro 100 mg from Merck Canada as marketed (Health Canada Drug Product Database, checked 2026-11-14).
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much is Pifeltro without insurance?
The U.S. list price is $1,839.90 for 30 tablets, a 30-day supply. Online pharmacies abroad charged from $1,944.95 for 90 days of brand Pifeltro in our latest check (Nov 12, 2026), shipping included.
Is there a generic Pifeltro?
No. Drugs@FDA lists no generic doravirine, so Merck's Pifeltro is the only version sold in the U.S.
Is Pifeltro a complete HIV regimen?
No. Pifeltro is taken together with other HIV medicines. Delstrigo combines doravirine with lamivudine and tenofovir disoproxil fumarate in one tablet.
How much does Pifeltro cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help.
Can I buy Pifeltro from Canada?
Pifeltro is sold in Canada by Merck. Federal law generally doesn't allow individuals to import prescription drugs, though the FDA has long used enforcement discretion for some personal-use shipments of up to a three-month supply. You need a prescription.
Sources
- Pifeltro U.S. prescribing information (DailyMed) (Merck label, version 21, effective 2026-07-08: HIV-1 with other antiretrovirals, adults and children 35 kg+; 100 mg once daily (twice daily with rifabutin))
- Drugs@FDA: Pifeltro (NDA 210806) (approved August 30, 2018; no ANDA for doravirine)
- FDA NDC Directory: Pifeltro (0006-3069-01 (30 tablets), Merck Sharp & Dohme, active; checked 2026-11-14)
- Texas DSHS 2026 WAC report: Pifeltro (Merck PIFELTRO 00006306901 (30 tablets) $1,839.90)
- Health Canada Drug Product Database: Pifeltro (DIN 02481545, Merck Canada, Marketed)
- HRSA: AIDS Drug Assistance Program
- Texas DSHS: 2026 annual WAC report
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.