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Isentress Cost, Generic and Savings
- U.S. list price
- $6,249.60 for 90 days (180 tablets)The maker's price for brand Isentress before discounts · Source: Texas DSHS 2026 WAC report
- Lowest international online pharmacy price
- $3.87 per tablet$710.75 for 90 days (180 tablets), shipping included · brand Isentress 400 mg, not FDA-approved · ships from Turkey
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Quick answerAs of Nov 11, 2026, brand Isentress 400 mg costs from $710.75 for 90 days at licensed pharmacies abroad we compared, vs. $6,249.60 at the U.S. list price ($2,083.20 for 60 tablets). FDA-approved generic raltegravir is now sold in the U.S.
Name check: Isentress HD is the 600 mg tablet of the same medicine, taken as two tablets once a day. Isentress chewable tablets and oral suspension are for children and aren't priced here.
Compare Isentress prices from licensed online pharmacies
For comparison U.S. pharmacy list price: $6,249.60 for 90 days ($34.72 per tablet), brand Isentress 400 mg or 600 mg before insurance. The prices below are from licensed online pharmacies outside the U.S.
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per tabletOnline pharmacy A | Brand Isentress 400mg400 mg · brand · Filled in TurkeyMade for sale in Turkey.Maker listed by pharmacy: MSD International | $695.80for 180 tablets$3.87 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $710.75 for 90 days= $710.75 for 90 daysSave 89%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy B | Brand Isentress 400mg400 mg · brand · Filled in IndiaMade for sale in India.Product of India | $486.05per 60 tablets · 3 packs = $1,458.15$8.10 per tablet | Fee not publishedDelivery time not stated | $1,458.15 for 90 days= $1,458.15 for 90 days+ shippingSave 77%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | Isentress400 mg · brand · Filled in AustraliaProduct of Australia | $1,885.60for 180 tablets$10.48 per tablet | Fee not publishedDelivery time not stated | $1,885.60 for 90 days= $1,885.60 for 90 days+ shippingSave 70%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy D | Isentress400 mg · brand · Filled in AustraliaProduct of Australia | $1,896.99for 180 tablets$10.54 per tablet | Fee not publishedDelivery time not stated | $1,896.99 for 90 days= $1,896.99 for 90 days+ shippingSave 70%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | ISENTRESS (EU pack, ships from Australia)400 mg · brand · Filled in AustraliaProduct of EU | $2,069.55for 180 tablets$11.50 per tablet | FreeDelivery time not stated | $2,069.55 for 90 days= $2,069.55 for 90 daysSave 67%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy F | ISENTRESS400 mg · brand · Filled in AustraliaProduct of Australia | $2,071.94for 180 tablets$11.51 per tablet | FreeDelivery time not stated | $2,071.94 for 90 days= $2,071.94 for 90 daysSave 67%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | ISENTRESS HD (Singapore pack, ships from Australia)600 mg · brand · Filled in AustraliaProduct of Singapore | $700.07per 60 tablets · 3 packs = $2,100.21$11.67 per tablet | FreeDelivery time not stated | $2,100.21 for 90 days= $2,100.21 for 90 daysSave 66%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy A | Brand Isentress 400mg400 mg · brand · Filled in AustraliaMaker listed by pharmacy: Merck Sharp & Dohme | $2,214.97for 180 tablets$12.31 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $2,229.92 for 90 days= $2,229.92 for 90 daysSave 64%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy G | Brand Isentress 400mg400 mg · brand · Filled in AustraliaMaker listed by pharmacy: Merck Sharp & Dohme | $763.60per 60 tablets · 3 packs = $2,290.80$12.73 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $2,305.75 for 90 days= $2,305.75 for 90 daysSave 63%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy H | ISENTRESS 400MG TABLET 180 (BRAND FROM AUSTRALIA)400 mg · brand · Filled in AustraliaProduct of Australia | $2,312.50for 180 tablets$12.85 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $2,327.45 for 90 days= $2,327.45 for 90 daysSave 63%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy I | Brand Isentress 400mg400 mg · brand · Filled in AustraliaMaker listed by pharmacy: Merck Sharp & Dohme | $790.87per 60 tablets · 3 packs = $2,372.61$13.18 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $2,387.56 for 90 days= $2,387.56 for 90 daysSave 62%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy J | Isentress400 mg · brand · Filled in AustraliaMaker listed by pharmacy: Merck Sharp & Dohme | $2,448.30for 180 tablets$13.60 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $2,463.25 for 90 days= $2,463.25 for 90 daysSave 61%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy K | Isentress (Australia pack, ships from New Zealand)400 mg · brand · Filled in New ZealandMaker listed by pharmacy: Merck Sharp & DohmeMade for Australia | $2,528for 180 tablets$14.04 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $2,537.95 for 90 days= $2,537.95 for 90 daysSave 59%incl. $9.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed online pharmacy L | Isentress 400mg400 mg · brand · Filled in AustraliaProduct of Australia | $854per 60 tablets · 3 packs = $2,562$14.23 per tablet | FreeDelivery time not stated | $2,562 for 90 days= $2,562 for 90 daysSave 59%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy K | Isentress HD (Australia pack, ships from New Zealand)600 mg · brand · Filled in New ZealandMaker listed by pharmacy: Merck Sharp & DohmeMade for Australia | $2,715for 180 tablets$15.08 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $2,724.95 for 90 days= $2,724.95 for 90 daysSave 56%incl. $9.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy J | Isentress HD600 mg · brand · Filled in AustraliaMaker listed by pharmacy: Merck Sharp & Dohme | $939.37per 60 tablets · 3 packs = $2,818.11$15.66 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $2,833.06 for 90 days= $2,833.06 for 90 daysSave 55%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy M | Isentress400 mg · brand · Filled in AustraliaProduct of Australia | $3,108.61for 180 tablets$17.27 per tablet | $9.95Delivery time not stated | $3,118.56 for 90 days= $3,118.56 for 90 daysSave 50%incl. $9.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy H | ISENTRESS 400MG TABLET 60 (BRAND FROM AUSTRALIA)400 mg · brand · Filled in AustraliaProduct of Australia | $1,158.75per 60 tablets · 3 packs = $3,476.25$19.31 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $3,491.20 for 90 days= $3,491.20 for 90 daysSave 44%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed Canadian pharmacy N | Isentress400 mg · brand · Filled in CanadaMaker listed by pharmacy: MERCK CANADA INC | $3,703.44for 180 tablets$20.57 per tablet | $9.95Pharmacy's estimate: 3–6 weeks | $3,713.39 for 90 days= $3,713.39 for 90 daysSave 41%incl. $9.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy A | Brand Isentress 400mg400 mg · brand · Filled in CanadaMaker listed by pharmacy: MERCK CANADA INC | $3,790.86for 180 tablets$21.06 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $3,805.81 for 90 days= $3,805.81 for 90 daysSave 39%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy K | Isentress400 mg · brand · Filled in CanadaMaker listed by pharmacy: Merck Sharp & Dohme | $3,867for 180 tablets$21.48 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $3,876.95 for 90 days= $3,876.95 for 90 daysSave 38%incl. $9.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy I | Brand Isentress Hd 600mg600 mg · brand · Filled in CanadaMaker listed by pharmacy: MERCK CANADA INC | $3,917.40for 180 tablets$21.76 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $3,932.35 for 90 days= $3,932.35 for 90 daysSave 37%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy I | Brand Isentress 400mg400 mg · brand · Filled in CanadaMaker listed by pharmacy: MERCK CANADA INC | $4,167.95for 180 tablets$23.16 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $4,182.90 for 90 days= $4,182.90 for 90 daysSave 33%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy K | Isentress HD600 mg · brand · Filled in CanadaMaker listed by pharmacy: Merck Sharp & Dohme | $4,257for 180 tablets$23.65 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $4,266.95 for 90 days= $4,266.95 for 90 daysSave 32%incl. $9.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy G | Brand Isentress 400mg400 mg · brand · Filled in CanadaMaker listed by pharmacy: MERCK CANADA INC | $4,376.35for 180 tablets$24.31 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $4,391.30 for 90 days= $4,391.30 for 90 daysSave 30%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy OU.S. shipping limited | Isentress (Raltegravir)400 mg · brand · Filled in TurkeyMade for sale in Turkey.Product of Turkey | $950per 60 tablets · 3 packs = $2,850$15.83 per tablet | $14.95Pharmacy's estimate: 8–14 business days | $2,864.95 for 90 days= $2,864.95 for 90 daysSave 54%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Isentress from Canada?
90-day cost = 180 tablets at the usual dose of 2 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price of the same strength (400 mg or 600 mg). The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
Members see pharmacy names, ratings, visit links and price-drop alerts.
Join to See PharmaciesAlready a member? Sign inIsentress price by strength
| Strength | Lowest brand90 days | Price per tablet |
|---|---|---|
| Isentress 400 mg | $710.75 | $3.87 |
| Isentress 600 mg | $2,100.21 | $11.67 |
Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per tablet is for that lowest pack, before shipping. Prices checked Nov 11, 2026.
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90-day prices from 11 licensed pharmacies shipping to the U.S.: $710.75 to $4,391.30, any strength, shipping included.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Isentress · Similar drugs · Uses · FAQ
Isentress (raltegravir) treats HIV together with other HIV medicines. Adults take 400 mg twice a day or Isentress HD 600 mg as two tablets once a day. Generic raltegravir is now sold in the U.S.
Other Ways to Pay for Isentress
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
Other ways to pay, useful if you have insurance or Medicare:
- Merck Patient Assistance Program (free Isentress if uninsured): Merck gives Isentress free of charge to eligible U.S. residents (including U.S. territories) who have no insurance or other coverage for the medicine and household income of $79,800 or less for one person, $108,200 for a couple or $165,000 for a family of 4. People with special financial and medical hardship can ask for an exception. One application can cover up to a year. Call 800-727-5400, Monday to Friday, 8 AM to 8 PM ET. (Merck Helps)
We list these because they may save you money. No one pays us to include them. Prices and eligibility rules change, so confirm before you buy. Checked Nov 11, 2026.
Isentress cost at a glance
- Generic Isentress is sold in the U.S. The FDA approved generic raltegravir 400 mg tablets from Hetero (sold by Camber since December 19, 2024) and 600 mg tablets from Lupin (listed since October 14, 2026), both rated equivalent to Isentress (FDA Orange Book). Ask your pharmacist for the generic price.
- U.S. list price: $2,083.20 for a bottle of 60 tablets of brand Isentress 400 mg or Isentress HD 600 mg. At 2 tablets a day that is a 30-day supply, or $6,249.60 for 90 days (Texas DSHS).
- Free medicine if uninsured: the Merck Patient Assistance Program gives Isentress free to eligible U.S. residents with no prescription coverage and household income of $79,800 or less for one person (Merck Helps).
- How we count: 2 tablets a day. The label doses Isentress 400 mg twice a day, and Isentress HD as two 600 mg tablets once a day.
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
- From online pharmacies abroad: $710.75 to $4,391.30 for 90 days of brand Isentress 400 mg, shipping included (checked Nov 11, 2026). The U.S. list price for 180 tablets (90 days) is $6,249.60.
How much does Isentress cost in the U.S.?
| If you have | What Isentress costs | Source |
|---|---|---|
| No insurance (list price) | $2,083.20 for 60 tablets of brand Isentress 400 mg or Isentress HD 600 mg (30 days at 2 a day; $6,249.60 for 90 days). Pharmacies may charge more. | Texas DSHS 2026 WAC report |
| No insurance (generic) | FDA-approved generic raltegravir 400 mg (Camber) and 600 mg (Lupin) tablets are sold in the U.S. Ask your pharmacist for the cash price. | FDA drug listing |
| No insurance (Merck Patient Assistance Program) | Free Isentress for U.S. residents with no prescription coverage and household income of $79,800 or less (single), $108,200 (couple) or $165,000 (family of 4). Call 800-727-5400. | Merck Helps |
| Private or employer insurance | Your copay depends on your plan and whether it covers the brand or the generic. | FDA Orange Book |
| Medicare Part D | Your plan sets the cost. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Brand Isentress lists at $2,083.20 for 60 tablets, about $34.72 a tablet (Texas DSHS). The 2026 price filing shows no list price yet for the newer generics. List prices are what makers charge wholesalers; what a pharmacy charges you can be higher or lower.
Isentress cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Isentress or generic raltegravir depends on your plan's drug list. People with limited income can apply for Extra Help.
| Medicare Part D | What Isentress costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Isentress coupons and savings programs
eDrugSearch does not offer its own Isentress coupons. These programs can help:
- Merck Patient Assistance Program: free Isentress for U.S. residents with no insurance or other prescription coverage (Medicare and Medicaid count as coverage) and household income of $79,800 or less for one person, $108,200 for a couple or $165,000 for a family of 4. Hardship exceptions may be possible. Call 800-727-5400. (Merck Helps)
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Isentress?
Yes. The FDA approved generic raltegravir 400 mg tablets from Hetero and 600 mg tablets from Lupin, both rated equivalent to Isentress. Camber (Hetero's U.S. partner) has listed its 400 mg generic as on the market since December 19, 2024, and Lupin has listed its 600 mg generic since October 14, 2026.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 400 mg | Yes | Hetero (Camber) | Dec 19, 2024 |
| 600 mg | Yes | Lupin | Oct 14, 2026 |
Outside the U.S.: Online pharmacies abroad may also sell generic raltegravir made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: FDA Orange Book: raltegravir products. As of Nov 11, 2026.
Compare Isentress with similar drugs
Other HIV medicines people often compare with Isentress. Tivicay is another integrase inhibitor, and Biktarvy, Dovato and Triumeq combine an integrase inhibitor with other HIV medicines in one pill. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Tivicaydolutegravir | HIV medicine (integrase inhibitor) | $1,381.29 for 90 days | See prices |
| Biktarvybictegravir, emtricitabine and tenofovir alafenamide | HIV medicine (complete one-pill regimen: integrase inhibitor plus two NRTIs) | $502.77 for 90 days | See prices |
| Dovatodolutegravir and lamivudine | HIV medicine (complete two-drug regimen: integrase inhibitor plus one NRTI) | $3,061.81 for 90 days | See prices |
| Triumeqabacavir, dolutegravir and lamivudine | HIV medicine (complete one-pill treatment) | $529.77 for 90 days | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Isentress used for?
Isentress (raltegravir) is an HIV medicine called an integrase inhibitor. According to its FDA label (DailyMed), it is used:
- With other HIV medicines, to treat HIV-1 infection in adults and children.
Adults take one 400 mg tablet twice a day, or, if they are starting treatment or are already well controlled on Isentress 400 mg twice a day, Isentress HD as two 600 mg tablets once a day. People taking rifampin take a higher dose. The chewable tablets and oral suspension are for children and can't be swapped for the film-coated tablets. Your prescriber decides which medicine is right for you.
Is it safe to order Isentress from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Isentress, compare the U.S. generic and Merck's patient assistance program before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, Isentress 400 mg and Isentress HD 600 mg are sold under the same names by Merck Canada (Health Canada).
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much is Isentress without insurance?
The U.S. list price of brand Isentress 400 mg is $2,083.20 for 60 tablets, which lasts 30 days at 2 tablets a day ($6,249.60 for 90 days). Isentress HD 600 mg has the same list price. Licensed pharmacies abroad charged from $710.75 for 90 days of brand Isentress 400 mg in our latest check (Nov 11, 2026).
Is there a generic for Isentress?
Yes. The FDA approved generic raltegravir 400 mg tablets from Hetero, sold by Camber since December 2024, and 600 mg tablets from Lupin, listed since October 2026. Both are rated equivalent to the brand. Ask your pharmacist whether a generic can fill your prescription.
Can I get Isentress for free?
Maybe. The Merck Patient Assistance Program gives Isentress free to U.S. residents with no prescription coverage and household income of $79,800 or less for one person, $108,200 for a couple or $165,000 for a family of 4. Call 800-727-5400.
How much does Isentress cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help.
What is the difference between Isentress and Isentress HD?
Both hold raltegravir. Isentress is a 400 mg tablet taken twice a day. Isentress HD is a 600 mg tablet taken as two tablets once a day, for adults and children weighing at least 40 kg who are starting treatment or already well controlled. Both list at $2,083.20 for 60 tablets. Your prescriber decides which medicine is right for you.
Why do I need two Isentress tablets a day?
The label doses Isentress 400 mg twice a day, and Isentress HD as two 600 mg tablets taken together once a day. Either way, a 60-tablet bottle lasts 30 days, so our 90-day prices are for 180 tablets.
Sources
- Texas DSHS: 2026 annual WAC report (Isentress 400 mg 60 tablets $2,083.20 (NDC 00006-0227-61); Isentress HD 600 mg 60 tablets $2,083.20 (NDC 00006-3080-01))
- ISENTRESS U.S. prescribing information (DailyMed) (Merck Sharp & Dohme, label version 71)
- Merck: Isentress and Isentress HD prescribing information (isentress.com opens this file, checked 2026-11-11)
- Drugs@FDA: Isentress (NDA 022145) (400 mg approved October 12, 2007; Isentress HD 600 mg)
- FDA Orange Book: raltegravir products (Hetero ANDA 203540 (400 mg, approved December 19, 2024); Lupin ANDA 217990 (600 mg, approved May 6, 2025))
- FDA NDC Directory: Camber raltegravir 400 mg (NDC 31722-584) (marketing start December 19, 2024)
- FDA NDC Directory: Lupin raltegravir 600 mg (NDC 70748-327) (marketing start October 14, 2026)
- Merck Patient Assistance Program: Isentress (income limits $79,800 / $108,200 / $165,000, checked 2026-11-11)
- Health Canada Drug Product Database: Isentress (DIN 02301881 (400 mg) and 02465337 (HD 600 mg), Merck Canada, marketed, checked 2026-11-11)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.