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Pertzye Cost, Coupons and Savings
- Lowest price per capsule at U.S. online pharmacies
- $8.67 per capsuleIn a pack of 360 capsules for $3,121.73 (before shipping) · FDA-approved brand Pertzye 24000 units · ships within the U.S.
- Lowest price per capsule at online pharmacies abroad
- Not available
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Quick answerBrand Pertzye has U.S. list prices from $187.46 for 100 capsules of 4,000 units to $671.56 for 80 capsules of 24,000 units, about $1.87 to $8.39 per capsule. No generic Pertzye is sold in the U.S. Ask your pharmacist what you would pay.
Name check: Strengths are named by lipase units per capsule. Other enzyme brands such as Creon or Zenpep aren't interchangeable with Pertzye and aren't priced here.
Compare Pertzye prices from licensed online pharmacies
| Pharmacy | Medication | Pack | Price per unit | Pack price | Shipping & delivery | Total with shipping | Buy |
|---|---|---|---|---|---|---|---|
| Lowest price per unitLicensed U.S. pharmacy A | Pertzye Delayed Release Capsule16000 units · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | 360 capsules2 other pack sizes
| $6.02 per capsule | $2,167.35 | FreePharmacy's estimate: 3–5 business days | $2,167.35Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitLicensed U.S. pharmacy B | Pertzye 16000 Unit DR Capsule16000 units · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | 90 capsules2 other pack sizes
| $6.24 per capsule | $561.60 | $5Pharmacy's estimate: 2–8 business days | $566.60Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitLicensed U.S. pharmacy A | Pertzye Delayed Release Capsule24000 units · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | 360 capsules2 other pack sizes
| $8.67 per capsule | $3,121.73 | FreePharmacy's estimate: 3–5 business days | $3,121.73Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Pertzye from Canada?
Each row is one product from one pharmacy, shown in the pack size with the lowest price per unit; its other pack sizes are listed under “other pack sizes”. Price per unit = the pack price divided by the units in the pack, before shipping; we sort by it and don't assume how long a pack lasts. Total with shipping = the pack price plus the pharmacy's shipping fee for one order. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars (converted when a pharmacy prices in Canadian dollars). The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, plus its standard shipping; no insurance or discount cards.
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Jump to: U.S. cost · Medicare · Coupons & savings · Generic Pertzye · Similar drugs · Uses · FAQ
Pertzye (pancrelipase) delayed-release capsules for exocrine pancreatic insufficiency, in four lipase strengths. No generic is sold in the U.S.
Pertzye cost at a glance
- U.S. list price: per bottle of brand Pertzye, $187.46 for 100 capsules of 4,000 units, $279.75 for 100 of 8,000 units, $559.50 for 100 of 16,000 units and $671.56 for 80 of 24,000 units. That is the maker's wholesale price before discounts (Texas DSHS).
- How we compare: the dose is set for each person by body weight or the fat in meals, so there's no standard number of capsules a day. We list each pharmacy's packs as sold and compare the price per capsule.
- No U.S. generic: no generic pancrelipase is sold in the U.S. Pertzye is approved as a biologic, and its label says not to swap in other pancreatic enzyme products (DailyMed).
- From online pharmacies abroad: we found no Pertzye offers that met our listing rules in our latest check. The price table shows the U.S. online pharmacy prices we found (checked Nov 11, 2026).
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
How much does Pertzye cost in the U.S.?
| If you have | What Pertzye costs | Source |
|---|---|---|
| No insurance (list price) | Per capsule at list price: about $1.87 (4,000 units), $2.80 (8,000 units), $5.60 (16,000 units) and $8.39 (24,000 units), from bottles of 100 (80 for 24,000 units). Larger bottles of 250 or 200 cost the same per capsule. Pharmacies may charge more. | Texas DSHS 2026 WAC report |
| Private or employer insurance | Your copay depends on your plan's drug list. Ask your plan or pharmacist what you'd pay for Pertzye. | Drugs@FDA |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Brand Pertzye's U.S. list prices range from $187.46 for 100 capsules of 4,000 units to $671.56 for 80 capsules of 24,000 units (Texas DSHS). That works out to about $1.87 to $8.39 per capsule. This is the maker's wholesale price before discounts; what a pharmacy charges can differ. How long a bottle lasts depends on your prescribed dose.
Pertzye cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Pertzye depends on your plan's drug list.
| Medicare Part D | What Pertzye costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Pertzye coupons and savings programs
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
Checking more than one medicine? Use the free Medicare Drug Cost Check.
eDrugSearch does not offer its own Pertzye coupons. These programs can help with the cost of Pertzye:
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Pertzye?
No. No generic pancrelipase is sold in the U.S. Pertzye is approved as a biologic (BLA 022175), and its FDA label says not to substitute other pancreatic enzyme products for it.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 4,000 USP units | No | — | |
| 8,000 USP units | No | — | |
| 16,000 USP units | No | — | |
| 24,000 USP units | No | — |
Outside the U.S.: Pancreatic enzyme products sold abroad under other names are different products. They are not FDA-approved versions of Pertzye and are not priced on this page.
Source: Drugs@FDA: PERTZYE (BLA 022175). As of Nov 11, 2026.
Compare Pertzye with similar drugs
Other pancreatic enzyme medicines people often compare with Pertzye. They aren't interchangeable, so your prescriber decides which one you take. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Pancreazepancrelipase | Pancreatic enzyme replacement (pancrelipase) | From $0.92 per capsule | See prices |
| Viokacepancrelipase | Pancreatic enzyme replacement (pancrelipase) | From $0.44 per tablet | See prices |
Lowest price per unit, before shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Pertzye used for?
Pertzye (pancrelipase) is a mix of digestive enzymes (lipase, protease and amylase) from pig pancreas. According to its FDA label (DailyMed), it is used:
- To treat exocrine pancreatic insufficiency (when the pancreas doesn't make enough enzymes to digest food) in adults and children.
Pertzye is taken with meals and snacks, and the dose is based on lipase units. The label starts adults and children 4 and older at 500 lipase units per kilogram of body weight per meal, adjusted to symptoms, with about half a meal dose for each snack. Capsules are swallowed whole, or opened and sprinkled on soft acidic food such as applesauce, but never crushed or chewed. The label warns about fibrosing colonopathy, a rare bowel narrowing linked to high doses. It has no boxed warning and no contraindications. Your prescriber decides which medicine is right for you.
Is it safe to order Pertzye from Canada?
Many Americans do, but U.S. law and customs rules apply, and Pertzye has no U.S. generic, so compare the price per capsule at your prescribed dose before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027.
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much is Pertzye without insurance?
The U.S. list price of brand Pertzye ranges from $187.46 for 100 capsules of 4,000 units to $671.56 for 80 capsules of 24,000 units (the maker's wholesale price before discounts). Ask your pharmacist what you would pay.
Is there a generic Pertzye?
No. No generic pancrelipase is sold in the U.S. Other enzyme brands, such as Creon or Zenpep, are separate products, and Pertzye's label says not to swap them in. Your prescriber decides which medicine is right for you.
What strengths does Pertzye come in?
Pertzye capsules come in four strengths, named by lipase units per capsule: 4,000, 8,000, 16,000 and 24,000 USP units. Each also contains protease and amylase.
How many Pertzye capsules will I need?
It depends on your weight, your meals and your symptoms. The label bases the dose on lipase units per kilogram per meal, with a smaller dose for snacks. Your prescription says how many capsules to take.
Is there a Pertzye coupon or savings card?
eDrugSearch doesn't offer coupons of its own. Ask your pharmacist or the maker about current offers. If you have Medicare and limited income, Extra Help can lower what you pay for prescriptions.
How much does Pertzye cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help.
Sources
- Texas DSHS: 2026 annual WAC report (Digestive Care PERTZYE: 4,000 x100 $187.46 (59767-0004-01); 8,000 x100 $279.75, x250 $699.38; 16,000 x100 $559.50, x250 $1,398.75; 24,000 x80 $671.56, x200 $1,678.90)
- PERTZYE U.S. prescribing information (DailyMed) (Digestive Care, label version 22, effective March 11, 2024: use, dose, administration, warnings)
- Drugs@FDA: PERTZYE (BLA 022175) (four strengths, Prescription, no therapeutic-equivalence code; approved May 17, 2012; checked 2026-11-11)
- FDA NDC Directory: Pertzye (NDCs 59767-004, -008, -016, -024, Digestive Care, Inc.)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.