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Pancreaze Cost, Coupons and Savings
- Lowest price per capsule at U.S. online pharmacies
- $5.43 per capsuleIn a pack of 360 capsules for $1,953.16 (before shipping) · FDA-approved brand Pancreaze 16,800 USP units · ships within the U.S.
- Lowest price per capsule at online pharmacies abroad
- $3.28 per capsuleIn a pack of 100 capsules for $328 (before shipping) · brand Pancreaze 16,800 USP units, not FDA-approved · ships from Canada
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Quick answerAs of Nov 11, 2026, brand Pancreaze 16,800 USP units costs from $3.28 per capsule at the pharmacies we compared, before shipping (sold in Canada as Pancrease MT 16). No generic is sold in the U.S. With commercial insurance, Vivus's savings card may cut your copay to $0.
Name check: Capsule strengths are named by lipase units. The dose depends on body weight or the fat in meals, so we compare prices per capsule and list each pack as sold.
Compare Pancreaze prices from licensed online pharmacies
| Pharmacy | Medication | Pack | Price per unit | Pack price | Shipping & delivery | Total with shipping | Buy |
|---|---|---|---|---|---|---|---|
| Lowest price per unitOnline pharmacy A | Pancrease MT 4 (sold in Canada as Pancrease MT)4,200 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $0.86 per capsule | $85.86 | Fee not publishedDelivery time not stated | $85.86+ shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy B | Pancrease MT 4 (sold in Canada as Pancrease MT)4,200 USP units · brand · Filled in CanadaMaker listed by pharmacy: Janssen Pharmaceuticals | 100 capsules | $0.92 per capsule | $92 | $9.95Pharmacy's estimate: 4–6 weeks | $101.95Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy C | Pancrease MT 4 (sold in Canada as Pancrease MT)4,200 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $0.97 per capsule | $96.99 | Fee not publishedDelivery time not stated | $96.99+ shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy D | Pancrease MT 4 (sold in Canada as Pancrease MT)4,200 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $1.47 per capsule | $147.34 | $9.95Delivery time not stated | $157.29Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitLicensed U.S. pharmacy E | PancreAze Delayed Release Capsule4,200 USP units · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | 360 capsules2 other pack sizes
| $1.50 per capsule | $541.71 | FreePharmacy's estimate: 3–5 business days | $541.71Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitLicensed U.S. pharmacy F | Pancreaze 4,200 Unit Capsules- 100ct Bottle4,200 USP units · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | 300 capsules2 other pack sizes
| $1.60 per capsule | $480.36 | $5Pharmacy's estimate: 2–8 business days | $485.36Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy G | PANCREAZE MT 4 (sold in Canada as Pancrease MT)4,200 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $1.70 per capsule | $170.35 | FreeDelivery time not stated | $170.35Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy H | PANCREAZE MT 4 (sold in Canada as Pancrease MT)4,200 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $1.73 per capsule | $172.74 | FreeDelivery time not stated | $172.74Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitLicensed Canadian pharmacy I | Pancreaze mt 4 4200/17500/10000 USP (sold in Canada as Pancrease MT)4,200 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $1.76 per capsule | $176 | FreeDelivery time not stated | $176Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy A | Pancrease MT 10 (sold in Canada as Pancrease MT)10,500 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $2.02 per capsule | $201.70 | Fee not publishedDelivery time not stated | $201.70+ shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy C | Pancrease MT 10 (sold in Canada as Pancrease MT)10,500 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $2.13 per capsule | $212.99 | Fee not publishedDelivery time not stated | $212.99+ shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy B | Pancrease MT 10 (sold in Canada as Pancrease MT)10,500 USP units · brand · Filled in CanadaMaker listed by pharmacy: Janssen Pharmaceuticals | 100 capsules | $2.19 per capsule | $219 | $9.95Pharmacy's estimate: 4–6 weeks | $228.95Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitLicensed Canadian pharmacy I | Pancreaze mt 10 10500/43750/25000 USP (sold in Canada as Pancrease MT)10,500 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $3.12 per capsule | $312 | FreeDelivery time not stated | $312Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy A | Pancrease MT 16 (sold in Canada as Pancrease MT)16,800 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $3.18 per capsule | $317.51 | Fee not publishedDelivery time not stated | $317.51+ shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy G | PANCREAZE MT 10 (sold in Canada as Pancrease MT)10,500 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $3.19 per capsule | $318.52 | FreeDelivery time not stated | $318.52Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy H | PANCREAZE MT 10 (sold in Canada as Pancrease MT)10,500 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $3.21 per capsule | $320.91 | FreeDelivery time not stated | $320.91Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy B | Pancrease MT 16 (sold in Canada as Pancrease MT)16,800 USP units · brand · Filled in CanadaMaker listed by pharmacy: Janssen Pharmaceuticals | 100 capsules | $3.28 per capsule | $328 | $9.95Pharmacy's estimate: 4–6 weeks | $337.95Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy C | Pancrease MT 16 (sold in Canada as Pancrease MT)16,800 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $3.29 per capsule | $328.99 | Fee not publishedDelivery time not stated | $328.99+ shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitLicensed U.S. pharmacy E | PancreAze Delayed Release Capsule10,500 USP units · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | 360 capsules2 other pack sizes
| $3.60 per capsule | $1,294.45 | FreePharmacy's estimate: 3–5 business days | $1,294.45Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy D | Pancrease MT 10 (sold in Canada as Pancrease MT)10,500 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $3.67 per capsule | $366.56 | $9.95Delivery time not stated | $376.51Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitLicensed Canadian pharmacy I | Pancreaze mt 16 16800/70000/40000 USP (sold in Canada as Pancrease MT)16,800 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $4.42 per capsule | $442 | FreeDelivery time not stated | $442Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy G | PANCREAZE MT 16 (sold in Canada as Pancrease MT)16,800 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $4.76 per capsule | $475.80 | FreeDelivery time not stated | $475.80Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy H | PANCREAZE MT 16 (sold in Canada as Pancrease MT)16,800 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $4.78 per capsule | $478.19 | FreeDelivery time not stated | $478.19Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitLicensed U.S. pharmacy E | PancreAze Delayed Release Capsule16,800 USP units · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | 360 capsules2 other pack sizes
| $5.43 per capsule | $1,953.16 | FreePharmacy's estimate: 3–5 business days | $1,953.16Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy D | Pancrease MT 16 (sold in Canada as Pancrease MT)16,800 USP units · brand · Filled in CanadaProduct of Canada | 100 capsules | $5.59 per capsule | $559.45 | $9.95Delivery time not stated | $569.40Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Pancreaze from Canada?
| Strength | Lowest brandper unit, before shipping | Lowest generic abroadper unit, not FDA-approved |
|---|---|---|
| Pancreaze 4,200 USP units | $0.92 per capsule | — |
| Pancreaze 10,500 USP units | $2.19 per capsule | — |
| Pancreaze 16,800 USP units | $3.28 per capsule | — |
Each row is one product from one pharmacy, shown in the pack size with the lowest price per unit; its other pack sizes are listed under “other pack sizes”. Price per unit = the pack price divided by the units in the pack, before shipping; we sort by it and don't assume how long a pack lasts. Total with shipping = the pack price plus the pharmacy's shipping fee for one order. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars (converted when a pharmacy prices in Canadian dollars). The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
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Prices per capsule from 5 licensed pharmacies abroad shipping to the U.S.: $0.92 to $5.59, any strength, before shipping.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Pancreaze · Similar drugs · Uses · FAQ
Pancreaze (pancrelipase) replaces digestive enzymes for people whose pancreas doesn't make enough. Capsules range from 2,600 to 37,000 lipase units.
Pancreaze cost at a glance
- No U.S. generic: no generic Pancreaze is sold in the U.S. It is approved as a biologic, and its label says not to swap in other pancreatic enzyme products (DailyMed).
- How we compare: the dose is set for each person by body weight or the fat in meals and snacks, so there's no set number of capsules a day. We list each pharmacy's packs as sold and compare the price per capsule. In the U.S., Pancreaze comes in bottles of 100 capsules (37,000 units: 2 bottles of 50).
- With commercial insurance: the Pancreaze Savings Card may lower your copay to as little as $0, saving up to $2,000 a fill and $3,500 a year (Pancreaze).
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
- From online pharmacies: $3.28 to $5.59 per capsule of brand Pancreaze 16,800 USP units (Canadian Pancrease MT 16 and U.S. packs), before shipping (checked Nov 11, 2026).
How much does Pancreaze cost in the U.S.?
| If you have | What Pancreaze costs | Source |
|---|---|---|
| No insurance | Ask your pharmacist for the cash price. If you're uninsured, Vivus's patient assistance program may provide Pancreaze at no cost if you qualify. | Pancreaze Engage Support Program |
| Private or employer insurance | Your copay depends on your plan. The Pancreaze Savings Card may lower it to as little as $0 (up to $2,000 a fill, $3,500 a year). | Pancreaze Engage Support Program |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Pancreaze is sold in the U.S. only as the Vivus brand; there is no generic. Its label says not to substitute other pancreatic enzyme products for it (DailyMed). What a pharmacy charges you depends on the strength and how many capsules your prescription calls for.
Pancreaze cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Pancreaze depends on your plan's drug list.
| Medicare Part D | What Pancreaze costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Pancreaze coupons and savings programs
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
Checking more than one medicine? Use the free Medicare Drug Cost Check.
eDrugSearch does not offer its own Pancreaze coupons. eDrugSearch has no coupons of its own. These programs can help with the cost of Pancreaze:
- Pancreaze Savings Card: for people with commercial insurance and a Pancreaze prescription. You may pay as little as $0, with savings of up to $2,000 per fill and $3,500 a year. Not for anyone covered in whole or in part by Medicare, Medicaid, Medigap, VA, DOD, TRICARE or any state or federal health program. (Pancreaze Engage Support Program)
- Pancreaze patient assistance: may provide Pancreaze at no cost if you're uninsured or your plan doesn't cover it, with household income at or below 300% of the federal poverty guidelines. People with Medicare Part D may qualify if they spend at least 4% of yearly income on prescriptions. You must live in the U.S. or a U.S. territory. (Pancreaze Engage Support Program)
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Pancreaze?
No. No generic Pancreaze is sold in the U.S. Pancreaze is approved as a biologic (BLA 022523), and its label says not to substitute other pancreatic enzyme products.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 2,600 USP units | No | — | |
| 4,200 USP units | No | — | |
| 10,500 USP units | No | — | |
| 16,800 USP units | No | — | |
| 21,000 USP units | No | — | |
| 37,000 USP units | No | — |
Outside the U.S.: Online pharmacies abroad may sell pancrelipase products made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: Drugs@FDA: Pancreaze (BLA 022523). As of Nov 11, 2026.
Compare Pancreaze with similar drugs
Other pancreatic enzyme medicines. The labels say not to swap one enzyme product for another, and your prescriber decides which medicine is right for you. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Viokacepancrelipase | Pancreatic enzyme replacement (pancrelipase) | From $0.44 per tablet | See prices |
| Pertzyepancrelipase | Pancreatic enzyme medicine | Checking prices | See prices |
Lowest price per unit, before shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Pancreaze used for?
Pancreaze (pancrelipase) is a mix of digestive enzymes taken from pig pancreas. According to its FDA label (DailyMed), it is used:
- To treat exocrine pancreatic insufficiency (EPI), when the pancreas doesn't make enough enzymes to digest food, in adults and children.
Pancreaze is taken with meals and snacks. The dose is based on lipase units and set for each person by body weight or the fat in the diet, with about half a meal dose for each snack. Capsules are swallowed whole. Your prescriber decides which medicine is right for you.
Is it safe to order Pancreaze from Canada?
Many Americans do, but U.S. law and customs rules apply. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, Vivus sells Pancrease MT capsules in 2,600 to 21,000 lipase unit strengths, the same lipase strengths as Pancreaze (Health Canada). The price table shows the name and country of each pack.
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much is Pancreaze without insurance?
It depends on the strength and how many capsules your prescription calls for, so ask your pharmacist for the cash price. The pharmacies we compared charged from $3.28 per capsule of Pancreaze 16,800 USP units in our latest check (Nov 11, 2026), before shipping. If you're uninsured, Vivus's patient assistance program may help.
Is there a generic for Pancreaze?
No. Pancreaze is a biologic with no generic sold in the U.S. Its label says not to substitute other pancreatic enzyme products for it.
Is there a Pancreaze coupon or savings card?
Yes, for people with commercial insurance. The Pancreaze Savings Card may lower your copay to as little as $0, saving up to $2,000 a fill and $3,500 a year. It can't be used with Medicare, Medicaid or other government plans. eDrugSearch doesn't offer coupons of its own.
How much does Pancreaze cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. Vivus's patient assistance program may help some people with Part D who meet its income rules.
Why is Pancreaze priced per capsule?
Because there's no standard daily dose. Your prescriber sets the number of capsules by your weight or the fat in your meals, so we compare the price per capsule and show each pack as the pharmacy sells it.
Can I buy Pancreaze from Canada?
In Canada, Vivus sells Pancrease MT capsules with the same lipase strengths as Pancreaze, from 2,600 to 21,000 units. The price table shows each pack's name and country, and labels packs that aren't FDA-approved.
Sources
- PANCREAZE U.S. prescribing information (DailyMed) (Vivus, label version 17 (effective June 6, 2025))
- Drugs@FDA: Pancreaze (BLA 022523) (approved April 12, 2010; six strengths, prescription)
- Pancreaze Engage Support Program (savings card: commercial only, as little as $0, up to $2,000 per fill and $3,500 a year; patient assistance at or below 300% FPL; checked 2026-11-11)
- Vivus press release: new copay assistance program for Pancreaze (February 11, 2026)
- Health Canada Drug Product Database: Pancrease MT (Vivus LLC; MT 2, 4, 10, 16, 20 (lipase 2,600 to 21,000 units), marketed; checked 2026-11-11)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.