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Envarsus XR Cost, Coupons and Savings

U.S. list price
$7.14 per tabletThe maker's price for brand Envarsus XR before discounts · Source: Texas DSHS 2026 WAC report
Lowest price per tablet at online pharmacies abroad
$3.58 per tabletIn a pack of 100 tablets for $357.99 (before shipping) · brand Envarsus XR 1 mg, not FDA-approved · ships from Canada
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Prices checked Nov 11, 2026 · Page updated November 12, 2026 · By the eDrugSearch team · How we check pharmacies and prices

Quick answerAs of Nov 11, 2026, brand Envarsus XR 1 mg costs from $3.58 per tablet abroad, before shipping, vs. about $7.14 a tablet at the U.S. list price ($214.34 per 30). No generic is sold in the U.S. With commercial insurance, the maker's card can lower your copay to $0.

Name check: Prograf, Astagraf XL and generic tacrolimus capsules are different tacrolimus products. The label says they can't be swapped with Envarsus XR, so they aren't priced here.

Compare Envarsus XR prices from licensed online pharmacies

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For comparison U.S. pharmacy list price: $7.14 per tablet, brand Envarsus XR 1 mg before insurance. The prices below are from licensed online pharmacies outside the U.S.

PharmacyMedicationPackPrice per unitPack priceShipping & deliveryTotal with shippingBuy
Online pharmacy ABrand Prograf 0.75mg (Envarsus) (Sold in Canada as Envarsus PA) (the pharmacy files it under Prograf; strength and maker match Envarsus PA)0.75 mg · brand · Filled in CanadaMaker listed by pharmacy: Paladin Labs Inc100 tablets$2.92 per tablet$291.79$14.95Pharmacy's estimate: 4–6 weeks$306.74Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy BEnvarsus (Sold in the U.K. as Envarsus)0.75 mg · brand · Filled in United KingdomMaker listed by pharmacy: Chiesi Limited60 tablets
2 other pack sizes
  • 90 tablets: $285 ($3.17 per tablet), $294.95 with shipping
  • 30 tablets: $99 ($3.30 per tablet), $108.95 with shipping
$3.17 per tablet$190$9.95Pharmacy's estimate: 4–6 weeks$199.95Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy CBrand Envarsus 0.75mg (Sold in Canada as Envarsus PA)0.75 mg · brand · Filled in CanadaMaker listed by pharmacy: Paladin Labs Inc100 tablets$3.20 per tablet$319.89$14.95Pharmacy's estimate: 4–6 weeks$334.84Checked Nov 11See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy DEnvarsus PA / XR (Tacrolimus) (Sold in Canada as Envarsus PA)0.75 mg · brand · Filled in CanadaProduct of Canada100 tablets$3.20 per tablet$319.95$14.99Delivery time not stated$334.94Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy EENVARSUS XR (Sold in Canada as Envarsus PA)0.75 mg · brand · Filled in CanadaProduct of Canada200 tablets
1 other pack size
  • 100 tablets: $376.13 ($3.76 per tablet), $376.13 with shipping
$3.47 per tablet$693.54FreeDelivery time not stated$693.54Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy FENVARSUS XL (Sold in the U.K. as Envarsus)0.75 mg · brand · Filled in UKProduct of UK90 tablets
1 other pack size
  • 30 tablets: $121.69 ($4.06 per tablet), $121.69 with shipping
$3.55 per tablet$319.53FreeDelivery time not stated$319.53Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy ABrand Prograf 1mg (Envarsus) (Sold in Canada as Envarsus PA) (the pharmacy files it under Prograf; strength and maker match Envarsus PA)1 mg · brand · Filled in CanadaMaker listed by pharmacy: Paladin Labs Inc100 tablets$3.58 per tablet$357.99$14.95Pharmacy's estimate: 4–6 weeks$372.94Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy CBrand Envarsus 1mg (Sold in Canada as Envarsus PA)1 mg · brand · Filled in CanadaMaker listed by pharmacy: Paladin Labs Inc100 tablets$3.92 per tablet$392.46$14.95Pharmacy's estimate: 4–6 weeks$407.41Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy GENVARSUS XR 1MG TABLET 300 (ENVARSUS PA BRAND FROM CANADA) (Sold in Canada as Envarsus PA)1 mg · brand · Filled in CanadaProduct of Canada300 tablets$3.93 per tablet$1,180$14.95Pharmacy's estimate: 4–6 weeks$1,194.95Checked Nov 11See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy DEnvarsus PA / XR (Tacrolimus) (Sold in Canada as Envarsus PA)1 mg · brand · Filled in CanadaProduct of Canada100 tablets$4.00 per tablet$399.95$14.99Delivery time not stated$414.94Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy HEnvarsus PR (Tacrolimus) (Sold in the U.K. as Envarsus)0.75 mg · brand · Filled in United KingdomMaker listed by pharmacy: Chiesi Limited90 tablets
2 other pack sizes
  • 60 tablets: $253.21 ($4.22 per tablet), $253.21 with shipping
  • 30 tablets: $140.94 ($4.70 per tablet), $140.94 with shipping
$4.02 per tablet$361.90FreePharmacy's estimate: 2–3 weeks$361.90Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy GENVARSUS XR 1MG TABLET 100 (ENVARSUS PA BRAND FROM CANADA) (Sold in Canada as Envarsus PA)1 mg · brand · Filled in CanadaProduct of Canada100 tablets$4.24 per tablet$424$14.95Pharmacy's estimate: 4–6 weeks$438.95Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy EENVARSUS XR (Sold in Canada as Envarsus PA)1 mg · brand · Filled in CanadaProduct of Canada300 tablets
2 other pack sizes
  • 200 tablets: $873.42 ($4.37 per tablet), $873.42 with shipping
  • 100 tablets: $466.08 ($4.66 per tablet), $466.08 with shipping
$4.27 per tablet$1,280.75FreeDelivery time not stated$1,280.75Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy FENVARSUS PA (EU pack, ships from Canada) (Sold in Canada as Envarsus PA)1 mg · brand · Filled in CanadaProduct of EU100 tablets$4.49 per tablet$448.90FreeDelivery time not stated$448.90Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy FENVARSUS XL (Sold in the U.K. as Envarsus)1 mg · brand · Filled in UKProduct of UK90 tablets
1 other pack size
  • 30 tablets: $154.65 ($5.16 per tablet), $154.65 with shipping
$4.65 per tablet$418.41FreeDelivery time not stated$418.41Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy IEnvarsus PR (UK/EU pack, ships from United Kingdom) (Sold in the U.K. as Envarsus)1 mg · brand · Filled in United KingdomProduct of UK/EU30 tablets$5.07 per tablet$151.99$9.95Delivery time not stated$161.94Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy HEnvarsus PR (Tacrolimus) (Sold in the U.K. as Envarsus)1 mg · brand · Filled in United KingdomMaker listed by pharmacy: Chiesi Limited90 tablets
2 other pack sizes
  • 60 tablets: $345.80 ($5.76 per tablet), $345.80 with shipping
  • 30 tablets: $184.51 ($6.15 per tablet), $184.51 with shipping
$5.47 per tablet$491.97FreePharmacy's estimate: 2–3 weeks$491.97Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy IEnvarsus PR (UK/EU pack, ships from United Kingdom) (Sold in the U.K. as Envarsus)0.75 mg · brand · Filled in United KingdomProduct of UK/EU90 tablets
2 other pack sizes
  • 60 tablets: $374.58 ($6.24 per tablet), $384.53 with shipping
  • 30 tablets: $211.82 ($7.06 per tablet), $221.77 with shipping
$5.97 per tablet$537.33$9.95Delivery time not stated$547.28Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy ABrand Prograf 4mg (Envarsus) (Sold in Canada as Envarsus PA) (the pharmacy files it under Prograf; strength and maker match Envarsus PA)4 mg · brand · Filled in CanadaMaker listed by pharmacy: Paladin Labs Inc100 tablets$13.51 per tablet$1,350.94$14.95Pharmacy's estimate: 4–6 weeks$1,365.89Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy CBrand Envarsus 4mg (Sold in Canada as Envarsus PA)4 mg · brand · Filled in CanadaMaker listed by pharmacy: Paladin Labs Inc100 tablets$14.81 per tablet$1,481.03$14.95Pharmacy's estimate: 4–6 weeks$1,495.98Checked Nov 11See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy DEnvarsus PA / XR (Tacrolimus) (Sold in Canada as Envarsus PA)4 mg · brand · Filled in CanadaProduct of Canada100 tablets$15.00 per tablet$1,499.95$14.99Delivery time not stated$1,514.94Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy GENVARSUS XR 4MG TABLET 100 (ENVARSUS PA BRAND FROM CANADA) (Sold in Canada as Envarsus PA)4 mg · brand · Filled in CanadaProduct of Canada100 tablets$15.00 per tablet$1,500$14.95Pharmacy's estimate: 4–6 weeks$1,514.95Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy BEnvarsus (Sold in the U.K. as Envarsus)4 mg · brand · Filled in United KingdomMaker listed by pharmacy: Chiesi Limited30 tablets
2 other pack sizes
  • 60 tablets: $910 ($15.17 per tablet), $919.95 with shipping
  • 90 tablets: $1,365 ($15.17 per tablet), $1,374.95 with shipping
$15.17 per tablet$455$9.95Pharmacy's estimate: 4–6 weeks$464.95Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy FENVARSUS XL (Sold in the U.K. as Envarsus)4 mg · brand · Filled in UKProduct of UK90 tablets
1 other pack size
  • 30 tablets: $550.29 ($18.34 per tablet), $550.29 with shipping
$16.58 per tablet$1,492.27FreeDelivery time not stated$1,492.27Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy FENVARSUS PA (EU pack, ships from Canada) (Sold in Canada as Envarsus PA)4 mg · brand · Filled in CanadaProduct of EU100 tablets$16.80 per tablet$1,680.16FreeDelivery time not stated$1,680.16Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy EENVARSUS XR (Sold in Canada as Envarsus PA)4 mg · brand · Filled in CanadaProduct of Canada100 tablets$16.88 per tablet$1,688.08FreeDelivery time not stated$1,688.08Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy HEnvarsus PR (Tacrolimus) (Sold in the U.K. as Envarsus)4 mg · brand · Filled in United KingdomMaker listed by pharmacy: Chiesi Limited90 tablets
2 other pack sizes
  • 60 tablets: $1,192.50 ($19.88 per tablet), $1,192.50 with shipping
  • 30 tablets: $608.90 ($20.30 per tablet), $608.90 with shipping
$19.61 per tablet$1,765.03FreePharmacy's estimate: 2–3 weeks$1,765.03Checked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy IEnvarsus PR (UK/EU pack, ships from United Kingdom) (Sold in the U.K. as Envarsus)4 mg · brand · Filled in United KingdomProduct of UK/EU90 tablets
2 other pack sizes
  • 60 tablets: $1,815.87 ($30.26 per tablet), $1,825.82 with shipping
  • 30 tablets: $932.47 ($31.08 per tablet), $942.42 with shipping
$29.99 per tablet$2,699.27$9.95Delivery time not stated$2,709.22Checked Nov 11See pharmacy (members) Members see the pharmacy

Buying from a pharmacy outside the U.S.? Read Is it safe to order Envarsus XR from Canada?

StrengthLowest brandper unit, before shippingLowest generic abroadper unit, not FDA-approved
Envarsus XR 0.75 mg$2.92 per tablet—
Envarsus XR 1 mg$3.58 per tablet—
Envarsus XR 4 mg$13.51 per tablet—

Each row is one product from one pharmacy, shown in the pack size with the lowest price per unit; its other pack sizes are listed under “other pack sizes”. Price per unit = the pack price divided by the units in the pack, before shipping; we sort by it and don't assume how long a pack lasts. Total with shipping = the pack price plus the pharmacy's shipping fee for one order. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars (converted when a pharmacy prices in Canadian dollars). The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Prices change often; confirm at checkout.

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Prices per tablet from 9 licensed pharmacies shipping to the U.S.: $2.92 to $29.99, any strength, before shipping.

Jump to: U.S. cost · Medicare · Coupons & savings · Generic Envarsus XR · Similar drugs · Uses · FAQ

Envarsus XR (tacrolimus extended-release) tablets help prevent kidney transplant rejection, in 0.75, 1 and 4 mg. No generic is sold in the U.S.

Envarsus XR cost at a glance

  • No generic Envarsus XR in the U.S. Drugs@FDA lists Envarsus XR as the only approved tacrolimus extended-release tablet, and the FDA drug listing shows only Veloxis's brand (Drugs@FDA, checked 2026-11-11).
  • U.S. list price: $214.34 for 30 tablets of brand Envarsus XR 1 mg (the maker's wholesale price before discounts). The 0.75 mg lists at $160.76 and the 4 mg at $857.33 per 30 (Texas DSHS).
  • Maker's $0 copay card: with commercial insurance, you may pay as little as $0, with up to $9,200 a year in savings. Not for Medicare, Medicaid, TRICARE or other government plans, or for cash-paying patients (Envarsus XR terms).
  • How we count: prices are per tablet, with each pharmacy's packs listed as sold. Envarsus XR is taken once a day, and the label sets each person's dose by body weight or their earlier tacrolimus dose, then adjusts it with blood tests.
  • From online pharmacies abroad: $3.58 to $5.47 per tablet for brand Envarsus XR 1 mg, before shipping (checked Nov 11, 2026). The U.S. list price is about $7.14 a tablet.
  • With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).

How much does Envarsus XR cost in the U.S.?

If you haveWhat Envarsus XR costsSource
No insurance (list price)$214.34 for 30 tablets of brand Envarsus XR 1 mg ($714.45 for 100), $160.76 for 30 tablets of 0.75 mg, or $857.33 for 30 tablets of 4 mg. Pharmacies may charge more.Texas DSHS 2026 WAC report
Private or employer insuranceYour copay depends on your plan. With the maker's $0 Copay Card, you may pay as little as $0, up to $9,200 in savings a year.Envarsus XR savings and support
Medicare Part DYour cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100.Medicare.gov
MedicaidYour state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office.Medicaid.gov

Brand Envarsus XR 1 mg lists at $214.34 for 30 tablets in the U.S., about $7.14 a tablet (Texas DSHS). The 0.75 mg lists at $160.76 and the 4 mg at $857.33 per 30, and 100-tablet bottles cost about the same per tablet. These are list prices (the maker's wholesale price before discounts); what a pharmacy charges can differ.

Envarsus XR cost with Medicare in 2026

In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Envarsus XR depends on your plan's drug list. The maker's copay card can't be used with Medicare.

Medicare Part DWhat Envarsus XR costsSource
Part D deductibleNo Medicare drug plan may have a deductible above $615 in 2026. Some plans have none.Medicare.gov
Yearly out-of-pocket capOnce your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year.Medicare.gov

Envarsus XR coupons and savings programs

How do you pay?

We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.

eDrugSearch does not offer its own Envarsus XR coupons. eDrugSearch has no coupons of its own. These are the programs we could verify:

  • Envarsus XR $0 Copay Card: for kidney transplant patients with commercial insurance that covers Envarsus XR, age 17 or older and living in the U.S. You may pay as little as $0, with savings up to $9,200 a year; you pay anything above that. Not valid for cash-paying patients, when your insurance doesn't cover the drug, or for prescriptions paid by Medicaid, Medicare drug plans, TRICARE or other federal or state programs. Copay Support Line: 855-591-9134. (Envarsus XR savings and support)
  • Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
  • Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)

Is there a generic Envarsus XR?

No. No generic Envarsus XR is sold in the U.S. Drugs@FDA lists Envarsus XR (NDA 206406, approved July 10, 2015) as the only approved tacrolimus extended-release tablet, and the FDA drug listing shows only Veloxis's brand.

StrengthU.S. genericMakersSince
0.75 mgNo—
1 mgNo—
4 mgNo—

Outside the U.S.: Online pharmacies abroad may sell tacrolimus made for other markets. Most of it is immediate-release capsules or extended-release capsules, which are different products from Envarsus XR.

Source: Drugs@FDA: Envarsus XR (NDA 206406). As of Nov 11, 2026.

Compare Envarsus XR with similar drugs

Other medicines used after a transplant: Prograf (immediate-release tacrolimus), Astagraf XL (extended-release tacrolimus capsules), Rapamune (sirolimus), Neoral (cyclosporine) and Imuran (azathioprine). They can't be swapped for Envarsus XR without your transplant team. Prices are for each drug's lowest-priced strength.

DrugTypeLowest price we foundLink
PrograftacrolimusTransplant medicine (immunosuppressant)From $0.72 per capsuleSee prices
Astagraf XLtacrolimus extended-releaseAnti-rejection medicine (calcineurin inhibitor)From $1.47 per capsuleSee prices
RapamunesirolimusTransplant medicine (immunosuppressant)From $2.59 per tabletSee prices
Neoralcyclosporine (modified)Immunosuppressant (anti-rejection medicine)From $1.48 per capsuleSee prices
ImuranazathioprineImmunosuppressantFrom $0.30 per tabletSee prices

Lowest price per unit, before shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.

What is Envarsus XR used for?

Envarsus XR is an extended-release form of tacrolimus, an immunosuppressant (a calcineurin inhibitor). It lowers the immune system's response so the body is less likely to reject a new kidney. According to its FDA label (DailyMed), it is used, along with other medicines that prevent rejection:

  • To help prevent organ rejection in people who have just had a kidney transplant.
  • To help prevent organ rejection in kidney transplant patients switching from immediate-release tacrolimus.

Envarsus XR comes as 0.75 mg, 1 mg and 4 mg tablets taken once a day on an empty stomach, preferably in the morning, swallowed whole. The label sets the starting dose by body weight (new transplant) or as 80% of the earlier immediate-release tacrolimus dose (switching), then adjusts it with regular blood tests. Boxed warning: the label carries the FDA's strongest warning. Envarsus XR and other immunosuppressants raise the risk of serious infections and some cancers, which may lead to a hospital stay or death. Your prescriber decides which medicine is right for you.

Is it safe to order Envarsus XR from Canada?

Many Americans do, but U.S. law and customs rules apply, and for Envarsus XR, check the maker's copay card if you have commercial insurance. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, tacrolimus extended-release tablets are sold under the name Envarsus PA (0.75, 1 and 4 mg) by Knight Therapeutics (Health Canada).

Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.

Frequently asked questions

How much is Envarsus XR without insurance?

The U.S. list price of brand Envarsus XR 1 mg is $214.34 for 30 tablets, about $7.14 a tablet, in the Texas 2026 drug price filing. The 4 mg lists at $857.33 per 30. Licensed pharmacies abroad charged from $3.58 per tablet for brand Envarsus XR 1 mg in our latest check (Nov 11, 2026), before shipping.

Is there a generic Envarsus XR?

Not in the U.S. Drugs@FDA lists Envarsus XR as the only approved tacrolimus extended-release tablet. Generic tacrolimus capsules are sold, but they are different products, and the label says they can't be swapped with Envarsus XR.

Is there an Envarsus XR copay card?

Yes, for people with commercial insurance. With the Envarsus XR $0 Copay Card you may pay as little as $0, with savings up to $9,200 a year. It can't be used with Medicare, Medicaid, TRICARE or other government coverage, or if you pay cash. Call 855-591-9134.

How much does Envarsus XR cost with Medicare?

It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. The maker's copay card can't be used with Medicare, but people with limited income can apply for Extra Help.

What strengths does Envarsus XR come in?

Envarsus XR comes in 0.75 mg, 1 mg and 4 mg extended-release tablets, in bottles of 30 or 100 in the U.S. Our price table shows the price per tablet; your own dose is set by your transplant team.

Is Envarsus XR the same as Prograf or Astagraf XL?

No. All three contain tacrolimus, but Prograf is an immediate-release capsule taken every 12 hours, Astagraf XL is an extended-release capsule, and Envarsus XR is an extended-release tablet. The label says they can't be substituted for each other. Their prices aren't on this page.

Is Envarsus XR sold in Canada?

Under a different name. Health Canada lists Envarsus PA, tacrolimus extended-release tablets in 0.75 mg, 1 mg and 4 mg, sold by Knight Therapeutics, as marketed.

Does Envarsus XR have a boxed warning?

Yes. The label warns that Envarsus XR and other immunosuppressants raise the risk of serious infections and some cancers, which may lead to a hospital stay or death. Talk with your prescriber about these risks.

Sources

eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.