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Duexis Price, Generic and Savings
- Lowest U.S. online pharmacy price
- $2.55 per tablet$693.50 for 90 days (270 tablets), shipping included · FDA-approved generic ibuprofen and famotidine 800 - 26.6 mg · ships within the U.S.
- Lowest international online pharmacy price
- Not available
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Quick answerThe FDA lists brand Duexis as discontinued in the U.S. FDA-approved generic ibuprofen and famotidine tablets are sold here: 90-tablet bottles (about a month at 3 a day) list at $55.00 to $404.00, depending on the maker. Ask your pharmacist for the cash price.
Name check: Duexis is one tablet with both medicines in it. Plain ibuprofen and plain famotidine tablets are separate products and aren't priced here.
Compare Duexis prices from licensed online pharmacies
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per tabletLicensed U.S. pharmacy A | Ibuprofen/Famotidine 800 - 26.6 mg Tablet800 - 26.6 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $76.50per 30 tablets · 9 packs = $688.50$2.55 per tablet | $5Pharmacy's estimate: 2–8 business days | $693.50 for 90 days= $693.50 for 90 daysincl. $5 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Duexis from Canada?
90-day cost = 270 tablets at the usual dose of 3 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards.
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Jump to: U.S. cost · Medicare · Coupons & savings · Generic Duexis · Similar drugs · Uses · FAQ
Duexis (ibuprofen and famotidine) 800 mg/26.6 mg tablets for arthritis. The FDA lists the brand as discontinued; generics are sold in the U.S.
Duexis cost at a glance
- Brand Duexis is listed as discontinued in the U.S. The FDA's Drugs@FDA database lists Duexis as discontinued, with a Federal Register finding that it was not withdrawn for safety or effectiveness reasons (Drugs@FDA, checked 2026-11-11).
- Generic Duexis is sold in the U.S. The FDA has approved generic ibuprofen and famotidine 800 mg/26.6 mg tablets from several companies, rated equivalent to Duexis (FDA Orange Book). The Texas 2026 drug price filing lists 90-tablet bottles of the generic at list prices of $55.00 (Par) to $404.00 (Ascend) (Texas DSHS).
- U.S. list price for the brand: there isn't one on this page, because the FDA lists brand Duexis as discontinued in the U.S. U.S. list prices for the generic are shown above.
- How we count: 3 tablets a day. The label's recommended dose is one tablet three times a day, so a 90-tablet bottle lasts about 30 days and 90 days takes about 270 tablets.
- From online pharmacies abroad: we found no ibuprofen and famotidine offers that met our listing rules in our latest check. The price table shows the U.S. online pharmacy prices we found (checked Nov 11, 2026).
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
How much does Duexis cost in the U.S.?
| If you have | What Duexis costs | Source |
|---|---|---|
| No insurance (brand list price) | None. The FDA lists brand Duexis as discontinued in the U.S. FDA-approved generic ibuprofen and famotidine tablets are sold here; see the next row. | Drugs@FDA |
| No insurance (generic ibuprofen and famotidine) | FDA-approved generic ibuprofen and famotidine 800 mg/26.6 mg tablets are sold in the U.S. The Texas 2026 filing lists 90-tablet bottles (about 30 days at 3 a day) at $55.00 (Par) to $404.00 (Ascend) list price, depending on the maker. Ask your pharmacist for the cash price. | Texas DSHS 2026 WAC report |
| Private or employer insurance | Your copay depends on your plan's drug list. Ask your plan whether it covers generic ibuprofen and famotidine tablets. | FDA Orange Book |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
The FDA lists brand Duexis as discontinued in the U.S. (Drugs@FDA), so this page shows no U.S. list price for the brand. FDA-approved generic ibuprofen and famotidine tablets are sold by several U.S. makers. In the Texas 2026 drug price filing, 90-tablet bottles of the generic list at $55.00 (Par) to $404.00 (Ascend), depending on the maker (Texas DSHS). At 3 tablets a day, a 90-tablet bottle lasts about 30 days. These are list prices (the maker's wholesale price before discounts); what a pharmacy charges can differ.
Duexis cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for generic ibuprofen and famotidine tablets depends on your plan's drug list.
| Medicare Part D | What Duexis costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Duexis coupons and savings programs
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
Checking more than one medicine? Use the free Medicare Drug Cost Check.
eDrugSearch does not offer its own Duexis coupons. Brand Duexis is listed as discontinued in the U.S. These programs can help with the cost of the generic:
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Duexis?
Yes. The FDA has approved generic ibuprofen and famotidine 800 mg/26.6 mg tablets from Alkem (sold by Ascend), Ascent (also sold by Camber), PH Health (sold by Par) and Zydus, all rated equivalent to Duexis. Ascend's generic has been listed as on the market since August 4, 2021. The FDA lists brand Duexis as discontinued in the U.S.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 800 mg/26.6 mg | Yes | Alkem (Ascend), Ascent (Camber), PH Health (Par), Zydus | Aug 4, 2021 |
Outside the U.S.: Online pharmacies abroad may also sell ibuprofen and famotidine tablets made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: FDA Orange Book: ibuprofen and famotidine products. As of Nov 11, 2026.
Compare Duexis with similar drugs
Other arthritis pain medicines (NSAIDs) people often compare with Duexis. These don't contain famotidine. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Celebrexcelecoxib | Arthritis and pain medicine (NSAID, COX-2 inhibitor) | $26.65 for 90 days | See prices |
| Mobicmeloxicam | NSAID (anti-inflammatory pain reliever) | $26.14 for 90 days | See prices |
| Naprosynnaproxen | Pain and arthritis medicine (nonsteroidal anti-inflammatory drug, NSAID) | $70.11 for 90 days | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Duexis used for?
Duexis (ibuprofen and famotidine) combines ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), with famotidine, which lowers stomach acid. According to the FDA label for ibuprofen and famotidine tablets (DailyMed), it is used:
- To relieve the signs and symptoms of rheumatoid arthritis and osteoarthritis.
- To lower the risk of stomach and upper-gut (duodenal) ulcers in people who take ibuprofen for these conditions.
The label's recommended dose is one tablet three times a day, swallowed whole (not cut, chewed or crushed), at the lowest effective dose for the shortest time. The label has a boxed warning: NSAIDs raise the risk of serious heart and blood-vessel events, such as heart attack and stroke, and of serious stomach or gut bleeding, ulcers and tears, which can be fatal. It must not be used around heart bypass (CABG) surgery, or by people who have had asthma, hives or allergic-type reactions after aspirin or other NSAIDs. The clinical trials lasted no longer than 6 months. Your prescriber decides which medicine is right for you.
Is it safe to order Duexis from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Duexis, compare the U.S. price of FDA-approved generic ibuprofen and famotidine before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027.
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much is Duexis without insurance?
The FDA lists brand Duexis as discontinued in the U.S., so this page shows no U.S. list price for it. FDA-approved generic ibuprofen and famotidine tablets are sold here: the Texas 2026 drug price filing lists 90-tablet bottles (about a month at 3 a day) at $55.00 to $404.00, depending on the maker. Ask your pharmacist for the cash price.
Is there a generic Duexis?
Yes. The FDA has approved generic ibuprofen and famotidine 800 mg/26.6 mg tablets from several companies, rated equivalent to Duexis. Ask your pharmacist whether a generic can fill your prescription.
Was Duexis discontinued?
The FDA's Drugs@FDA database lists Duexis as discontinued in the U.S. and notes it was not withdrawn for safety or effectiveness reasons. Generic ibuprofen and famotidine tablets are still sold here.
Can I take ibuprofen and famotidine separately instead of Duexis?
The FDA label says not to substitute the combination tablet with separate ibuprofen and famotidine products. Ask your prescriber or pharmacist about your options. Your prescriber decides which medicine is right for you.
Is there a Duexis coupon or savings card?
eDrugSearch doesn't offer coupons of its own. Brand Duexis is listed as discontinued in the U.S. FDA-approved generic ibuprofen and famotidine tablets are sold here; ask your pharmacist for the cash price. If you have Medicare and limited income, Extra Help can lower what you pay for prescriptions.
How much does Duexis cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help.
How many Duexis tablets are in a 90-day supply?
About 270. The label's recommended dose is one tablet three times a day, so our price table counts every pack in 90-day amounts at 3 tablets a day. Duexis comes in one strength, 800 mg ibuprofen with 26.6 mg famotidine.
Sources
- Drugs@FDA: DUEXIS (NDA 022519) (800 mg/26.6 mg tablet listed as discontinued, with a Federal Register determination that it was not discontinued for safety or effectiveness reasons; checked 2026-11-11)
- FDA Orange Book: ibuprofen and famotidine products
- FDA NDC Directory: Ascend ibuprofen and famotidine (NDC 67877-626) (ANDA 211890 (Alkem), marketing start August 4, 2021)
- Texas DSHS: 2026 annual WAC report (generic ibuprofen and famotidine, 90-tablet bottles: $55.00 (Par, NDC 49884-0366-09), $404.00 (Ascend, NDC 67877-0626-90))
- Ibuprofen and famotidine tablets: U.S. prescribing information (DailyMed) (generic label (Ascend, ANDA 211890), effective 2026-10-23: uses, dose, boxed warning, contraindications)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.