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Naprosyn Cost, Generic and Savings
- Lowest U.S. online pharmacy price
- Not available
- Lowest international online pharmacy price
- $1.59 per tablet$296.73 for 90 days (180 tablets), shipping included · brand Naprosyn 500 mg, not FDA-approved · ships from United Kingdom
FDA-approved generic naproxen 500 mg from $27 for 90 days at U.S. pharmacies
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Quick answerAs of Nov 11, 2026, brand Naprosyn 500 mg costs from $296.73 for 90 days at licensed pharmacies abroad we compared. FDA-approved generic naproxen is sold in the U.S., listed at $9.25 for 100 tablets of 500 mg.
Name check: EC-Naprosyn (delayed-release) and naproxen sodium products such as Anaprox DS and Aleve are separate products. This page prices plain naproxen tablets.
Compare Naprosyn prices from licensed online pharmacies
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per tabletLicensed U.S. pharmacy A | Naproxen (Naprosyn)375 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $18for 180 tablets$0.10 per tablet | $5Pharmacy's estimate: 7–10 business days | $23 for 90 days= $23 for 90 daysincl. $5 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy A | Naproxen (Naprosyn)250 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $19for 180 tablets$0.11 per tablet | $5Pharmacy's estimate: 7–10 business days | $24 for 90 days= $24 for 90 daysincl. $5 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy A | Naproxen (Naprosyn)500 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $22for 180 tablets$0.12 per tablet | $5Pharmacy's estimate: 7–10 business days | $27 for 90 days= $27 for 90 daysincl. $5 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy B | Naproxen 250mg Tablet250 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $25per 90 tablets · 2 packs = $50$0.28 per tablet | FreePharmacy's estimate: 3–5 business days | $50 for 90 days= $50 for 90 daysincl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy B | Naproxen 375mg Tablet375 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $25per 90 tablets · 2 packs = $50$0.28 per tablet | FreePharmacy's estimate: 3–5 business days | $50 for 90 days= $50 for 90 daysincl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy B | Naproxen 500mg Tablet500 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $25per 90 tablets · 2 packs = $50$0.28 per tablet | FreePharmacy's estimate: 3–5 business days | $50 for 90 days= $50 for 90 daysincl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | NaproxenNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.500 mg · generic · Filled in CanadaMaker listed by pharmacy: Teva Pharmaceuticals | $29for 100 tablets$0.29 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $38.95 for 50 days= $70.11 for 90 daysWorked out from a 50-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy D | Naproxen 500mg Tablets500 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $73.80for 180 tablets$0.41 per tablet | $5Pharmacy's estimate: 2–8 business days | $78.80 for 90 days= $78.80 for 90 daysincl. $5 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | Naproxen (Naproxen)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.500 mg · generic · Filled in United KingdomProduct of United Kingdom | $51.08per 84 tablets · 2 packs = $102.16$0.61 per tablet | FreePharmacy's estimate: 2–3 weeks | $102.16 for 84 days= $109.46 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed Canadian pharmacy F | NaproxenNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.375 mg · generic · Filled in CanadaMaker listed by pharmacy: Apotex | $56.20for 100 tablets$0.56 per tablet | $9.95Pharmacy's estimate: 3–6 weeks | $66.15 for 50 days= $119.07 for 90 daysWorked out from a 50-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | Naproxen (Naproxen)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.375 mg · generic · Filled in CanadaMaker listed by pharmacy: Apotex Inc | $74.04for 100 tablets$0.74 per tablet | FreePharmacy's estimate: 2–3 weeks | $74.04 for 50 days= $133.27 for 90 daysWorked out from a 50-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | Naproxen (Naproxen)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.500 mg · generic · Filled in CanadaMaker listed by pharmacy: Apotex Inc | $76.14for 100 tablets$0.76 per tablet | FreePharmacy's estimate: 2–3 weeks | $76.14 for 50 days= $137.05 for 90 daysWorked out from a 50-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed Canadian pharmacy F | NaproxenNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.500 mg · generic · Filled in CanadaMaker listed by pharmacy: Apotex | $67.23for 100 tablets$0.67 per tablet | $9.95Pharmacy's estimate: 3–6 weeks | $77.18 for 50 days= $138.92 for 90 daysWorked out from a 50-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | NaproxenNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.250 mg · generic · Filled in United KingdomProduct of United Kingdom | $60per 84 tablets · 2 packs = $120$0.71 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $129.95 for 84 days= $139.23 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | Naproxen (Naproxen)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.250 mg · generic · Filled in United KingdomProduct of United Kingdom | $66.34per 84 tablets · 2 packs = $132.68$0.79 per tablet | FreePharmacy's estimate: 2–3 weeks | $132.68 for 84 days= $142.16 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | Naprosyn (Naproxen)250 mg · brand · Filled in United KingdomMaker listed by pharmacy: Roche | $164.26for 168 tablets$0.98 per tablet | FreePharmacy's estimate: 2–3 weeks | $164.26 for 84 days= $175.99 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy G | Naprosyn (UK/EU pack, ships from United Kingdom)250 mg · brand · Filled in United KingdomProduct of UK/EU | $158.99for 168 tablets$0.95 per tablet | $9.95Delivery time not stated | $168.94 for 84 days= $181.01 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | Naprosyn500 mg · brand · Filled in United KingdomMaker listed by pharmacy: Atnahs Pharma | $89per 56 tablets · 3 packs = $267$1.59 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $276.95 for 84 days= $296.73 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | Naprosyn (Naproxen)500 mg · brand · Filled in United KingdomMaker listed by pharmacy: Roche | $295.17for 168 tablets$1.76 per tablet | FreePharmacy's estimate: 2–3 weeks | $295.17 for 84 days= $316.25 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy HU.S. shipping limited | Naproxen (Generic)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.250 mg · generic · Filled in United KingdomProduct of United Kingdom | $68per 84 tablets · 2 packs = $136$0.81 per tablet | $14.95Pharmacy's estimate: 8–14 business days | $150.95 for 84 days= $161.73 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy HU.S. shipping limited | Naproxen (Generic)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.375 mg · generic · Filled in CanadaProduct of Canada | $84for 100 tablets$0.84 per tablet | $14.95Pharmacy's estimate: 8–14 business days | $98.95 for 50 days= $178.11 for 90 daysWorked out from a 50-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy HU.S. shipping limited | Naproxen (Generic)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.500 mg · generic · Filled in United KingdomProduct of United Kingdom | $81per 84 tablets · 2 packs = $162$0.96 per tablet | $14.95Pharmacy's estimate: 8–14 business days | $176.95 for 84 days= $189.59 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Naprosyn from Canada?
90-day cost = 180 tablets at the usual dose of 2 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards.
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Join to See PharmaciesAlready a member? Sign inNaprosyn price by strength
| Strength | Lowest brand90 days | Lowest generic abroad90 days, not FDA-approved | Price per tablet |
|---|---|---|---|
| Naprosyn 250 mg | $175.99 | $139.23 | $0.98 brand · $0.71 generic |
| Naprosyn 375 mg | — | $119.07 | $0.56 generic |
| Naprosyn 500 mg | $296.73 | $70.11 | $1.59 brand · $0.29 generic |
Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per tablet is for that lowest pack, before shipping. Prices checked Nov 11, 2026.
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90-day prices from 4 licensed pharmacies abroad shipping to the U.S.: $70.11 to $316.25, any strength, shipping included.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Naprosyn · Similar drugs · Uses · FAQ
Naprosyn (naproxen) tablets for arthritis and pain, in 250, 375 and 500 mg. FDA-approved generic naproxen tablets are widely sold in the U.S.
Naprosyn cost at a glance
- Generic Naprosyn is sold in the U.S. The FDA has approved generic naproxen tablets (250, 375 and 500 mg) from many companies, rated equivalent to Naprosyn (FDA Orange Book). In the Texas 2026 drug price filing, Aurobindo's generic lists at $6.05 (250 mg), $7.65 (375 mg) and $9.25 (500 mg) for 100 tablets (Texas DSHS).
- Brand Naprosyn in the U.S.: the FDA still lists Naprosyn 500 mg tablets (Atnahs Pharma) as a prescription product, and the 250 mg and 375 mg tablets as discontinued (Drugs@FDA). We found no Naprosyn-brand tablets in the FDA's current drug listing (checked 2026-11-11).
- How we count: 2 tablets a day. The label's arthritis dose is one tablet twice a day, so 180 tablets for 90 days. Doses for pain, gout and period cramps are different.
- From online pharmacies abroad: $296.73 to $316.25 for 90 days of brand Naprosyn 500 mg, shipping included (checked Nov 11, 2026).
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
How much does Naprosyn cost in the U.S.?
| If you have | What Naprosyn costs | Source |
|---|---|---|
| No insurance (generic naproxen) | FDA-approved generic naproxen tablets are sold in the U.S. In the Texas 2026 filing, Aurobindo's list price for 100 tablets is $6.05 (250 mg), $7.65 (375 mg) or $9.25 (500 mg). Ask your pharmacist for the cash price. | Texas DSHS 2026 WAC report |
| Private or employer insurance | Your copay depends on your plan and whether it covers brand Naprosyn or generic naproxen, which the FDA rates as equivalent to Naprosyn. | FDA Orange Book |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
The FDA lists the brand Naprosyn 500 mg tablet as a prescription product (Drugs@FDA), but no Naprosyn-brand tablets are in its current drug listing. FDA-approved generic naproxen tablets have been approved in the U.S. since 1993 and are sold by many makers. In the Texas 2026 drug price filing, Aurobindo's bottle of 100 tablets lists at $6.05 to $9.25, depending on the strength (Texas DSHS). That's 6 to 9 cents a tablet. List price is the maker's wholesale price before discounts, so pharmacies may charge more.
Naprosyn cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for brand Naprosyn or generic naproxen depends on your plan's drug list.
| Medicare Part D | What Naprosyn costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Naprosyn coupons and savings programs
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
eDrugSearch does not offer its own Naprosyn coupons. eDrugSearch has no coupons of its own. If you have Medicare, these programs can help with the cost of brand Naprosyn or generic naproxen:
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Naprosyn?
Yes. The FDA has approved generic naproxen tablets (250, 375 and 500 mg) from many companies, including Teva, Amneal, Glenmark, Zydus, Aurobindo, Dr. Reddy's and ScieGen, all rated equivalent to Naprosyn. The first generics were approved on December 21, 1993. Amneal's 500 mg generic has been listed as on the market since February 18, 2010.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 250 mg | Yes | Teva, Amneal, Glenmark, Zydus, Aurobindo, Dr. Reddy's, ScieGen and others | — |
| 375 mg | Yes | Teva, Amneal, Glenmark, Zydus, Aurobindo, Dr. Reddy's, ScieGen and others | — |
| 500 mg | Yes | Teva, Amneal, Glenmark, Zydus, Aurobindo, Dr. Reddy's, ScieGen and others | — |
Outside the U.S.: Online pharmacies abroad may also sell generic naproxen made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: FDA Orange Book: naproxen products. As of Nov 11, 2026.
Compare Naprosyn with similar drugs
Other medicines people often compare for pain and arthritis. Celebrex (celecoxib) and Mobic are also NSAIDs. Skelaxin is a muscle relaxant, a different kind of medicine. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Celebrexcelecoxib | Arthritis and pain medicine (NSAID, COX-2 inhibitor) | $26.65 for 90 days | See prices |
| Mobicmeloxicam | NSAID (anti-inflammatory pain reliever) | $26.14 for 90 days | See prices |
| Celecoxibcelecoxib | Arthritis and pain medicine (NSAID, COX-2 inhibitor), generic of Celebrex | $26.65 for 90 days | See prices |
| Skelaxinmetaxalone | Muscle relaxant | From $0.61 per tablet | See prices |
Lowest price from licensed pharmacies shipping to the U.S., any strength: 90-day prices include shipping; prices per unit are before shipping. Only your doctor can decide whether another drug is right for you.
What is Naprosyn used for?
Naprosyn (naproxen) is a nonsteroidal anti-inflammatory drug (NSAID). It eases pain and swelling. According to the FDA label for naproxen tablets (DailyMed), it is used to relieve the signs and symptoms of:
- Rheumatoid arthritis, osteoarthritis and ankylosing spondylitis (arthritis of the spine).
- Polyarticular juvenile idiopathic arthritis.
- Tendonitis and bursitis.
- Acute gout.
- Pain and painful periods (primary dysmenorrhea).
Naproxen tablets come in 250 mg, 375 mg and 500 mg. For arthritis, the label's dose is one tablet twice a day. Boxed warning: the label carries the FDA's strongest warning. NSAIDs raise the risk of serious heart and blood vessel problems, including heart attack and stroke, and of serious stomach and bowel bleeding, ulcers and tears, which can be fatal. Naproxen must not be used around heart bypass (CABG) surgery. The label says to use the lowest dose that works for the shortest time. Your prescriber decides which medicine is right for you.
Is it safe to order Naprosyn from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Naprosyn, compare the U.S. price of FDA-approved generic naproxen before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, the Naprosyn name is used for delayed-release (enteric-coated) 375 mg and 500 mg tablets and a 750 mg extended-release tablet, sold by Searchlight Pharma (Health Canada). Those are different forms from the plain U.S. Naprosyn tablet.
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much does Naprosyn cost without insurance?
Licensed pharmacies abroad charged from $296.73 for 90 days of brand Naprosyn 500 mg in our latest check (Nov 11, 2026). FDA-approved generic naproxen is sold in the U.S.: in the Texas 2026 drug price filing, Aurobindo's generic lists at $9.25 for 100 tablets of 500 mg. Ask your pharmacist for the cash price.
Is there a generic for Naprosyn?
Yes. The generic name is naproxen. The FDA has approved generic tablets (250, 375 and 500 mg) from many companies, rated equivalent to Naprosyn, and generics have been approved since 1993. Ask your pharmacist whether a generic can fill your prescription.
Is Naprosyn still sold in the U.S.?
The FDA still lists Naprosyn 500 mg tablets from Atnahs Pharma as a prescription product, and lists the 250 mg and 375 mg tablets as discontinued. We found no Naprosyn-brand tablets in the FDA's current drug listing when we checked on November 11, 2026. Generic naproxen tablets are widely sold.
How much is generic naproxen 500 mg?
In the Texas 2026 drug price filing, Aurobindo's generic naproxen 500 mg lists at $9.25 for 100 tablets. That's a list price, so what a pharmacy charges can differ. Pharmacies we compared charged from $70.11 for 90 days of generic naproxen 500 mg (Nov 11, 2026).
Is there a Naprosyn coupon or savings card?
eDrugSearch doesn't offer coupons of its own. FDA-approved generic naproxen is sold in the U.S.; ask your pharmacist for its cash price. If you have Medicare and limited income, Extra Help can lower what you pay for prescriptions.
How much does Naprosyn cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help.
Is Naprosyn the same as Aleve?
Not exactly. Naprosyn tablets contain naproxen. Aleve, sold without a prescription, contains naproxen sodium, a different form of the same medicine with its own strength. They're separate products, and this page prices prescription naproxen tablets only.
Does Naprosyn have a boxed warning?
Yes. Like other NSAIDs, naproxen's label warns of a higher risk of serious heart and blood vessel problems, such as heart attack and stroke, and of serious stomach and bowel bleeding and ulcers. Talk with your prescriber about these risks.
Sources
- Drugs@FDA: Naprosyn tablets (NDA 017581) (Atnahs Pharma US: 500 mg Prescription; 250 mg and 375 mg Discontinued; checked 2026-11-11)
- Drugs@FDA: EC-Naprosyn (NDA 020067) (375 and 500 mg delayed-release tablets, separate product)
- FDA NDC Directory: search for Naprosyn (no product listed under the Naprosyn name; checked 2026-11-11)
- FDA Orange Book: naproxen products (generic 250/375/500 mg tablets, TE code AB)
- Drugs@FDA data: first generic naproxen tablets (ANDA 074201, Teva) (approved December 21, 1993)
- FDA NDC Directory: Amneal naproxen 500 mg (NDC 65162-190) (ANDA 075927, marketing start February 18, 2010)
- Drugs@FDA: Anaprox DS (NDA 018164) (naproxen sodium, prescription; separate product)
- FDA NDC Directory: Aleve (naproxen sodium 220 mg, sold without a prescription (OTC))
- Naproxen tablets prescribing information (DailyMed) (Amneal, label dated March 2025, incl. boxed warning)
- Texas DSHS: 2026 annual WAC report (Aurobindo naproxen 100 tablets: 250 mg $6.05, 375 mg $7.65, 500 mg $9.25 (NDC 65862-520-01, -521-01, -522-01))
- Health Canada Drug Product Database: Naprosyn (Searchlight Pharma: 500 mg delayed-release (DIN 02162423) and 750 mg extended-release (DIN 02162466) marketed; 375 mg delayed-release (DIN 02162415) cancelled 2025-07-25; checked 2026-11-11)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.