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Duavee Cost, Coupons and Savings
- Lowest U.S. online pharmacy price
- $7.47 per tablet$677.30 for 90 days (90 tablets), shipping included · FDA-approved brand Duavee 0.45 mg/20 mg · ships within the U.S.
- Lowest international online pharmacy price
- $3.52 per tablet$316.71 for 90 days (90 tablets), plus shipping (fee not published) · brand Duavee 0.45 mg/20 mg, not FDA-approved · ships from Canada
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Quick answerAs of Nov 11, 2026, brand Duavee costs from $377.09 for 90 days at licensed pharmacies abroad we compared, vs. $608.55 at the U.S. list price ($202.85 for 30). TrumpRx.gov lists Duavee from $30.30 for 30 tablets with a coupon. No generic is sold in the U.S.
Name check: Duavee pairs conjugated estrogens (the hormone in Premarin) with bazedoxifene instead of a progestin. Prempro uses a progestin and is a separate medicine.
Duavee may cost less in the U.S.
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
The lowest price in our table is $377.09 (ships from Canada), shipping included. These programs can cost less:
- TrumpRx.gov coupon: The federal TrumpRx site lists brand Duavee from $30.30 for 30 tablets with its coupon, used at retail pharmacies that dispense Duavee (original price $202.00). TrumpRx calls it an out-of-pocket price and suggests that people with insurance check their copay first, since it may be lower. $90.90 for 90 days (TrumpRx.gov)
We list these because they may save you money. No one pays us to include them. Prices and eligibility rules change, so confirm before you buy. Checked Nov 11, 2026.
Compare Duavee prices from licensed online pharmacies
For comparison U.S. pharmacy list price: $608.55 for 90 days ($6.76 per tablet), brand Duavee before insurance. The prices below are from U.S. pharmacies that publish cash prices and from licensed online pharmacies outside the U.S.
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per tabletOnline pharmacy A | Duavive (sold outside the U.S. as Duavive)0.45 mg/20 mg · brand · Filled in CanadaProduct of Canada | $295.60for 84 tablets$3.52 per tablet | Fee not publishedDelivery time not stated | $295.60 for 84 days= $316.71 for 90 days+ shippingSave 48%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy B | Duavive (sold outside the U.S. as Duavive)0.45 mg/20 mg · brand · Filled in CanadaProduct of Canada | $305.99for 84 tablets$3.64 per tablet | Fee not publishedDelivery time not stated | $305.99 for 84 days= $327.85 for 90 days+ shippingSave 46%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | Duavive (sold outside the U.S. as Duavive)0.45 mg/20 mg · brand · Filled in CanadaMaker listed by pharmacy: Pfizer Inc | $342for 84 tablets$4.07 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $351.95 for 84 days= $377.09 for 90 daysSave 38%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy D | Duavive (Estrogens, Conjugated, Bazedoxifene) (sold outside the U.S. as Duavive)0.45 mg/20 mg · brand · Filled in CanadaMaker listed by pharmacy: Pfizer Inc | $373.29for 84 tablets$4.44 per tablet | FreePharmacy's estimate: 2–3 weeks | $373.29 for 84 days= $399.95 for 90 daysSave 34%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed Canadian pharmacy E | Duavive (sold outside the U.S. as Duavive)0.45 mg/20 mg · brand · Filled in CanadaMaker listed by pharmacy: Pfizer | $375.92for 84 tablets$4.48 per tablet | $9.95Pharmacy's estimate: 3–6 weeks | $385.87 for 84 days= $413.43 for 90 daysSave 32%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy F | DUAVEE0.45 mg/20 mg · brand · Filled in CanadaProduct of Canada | $521.95for 84 tablets$6.21 per tablet | FreeDelivery time not stated | $521.95 for 84 days= $559.23 for 90 daysSave 8%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy G | Duavive (sold outside the U.S. as Duavive)0.45 mg/20 mg · brand · Filled in CanadaProduct of Canada | $565.34for 84 tablets$6.73 per tablet | $9.95Delivery time not stated | $575.29 for 84 days= $616.38 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy H | Duavee 0.45-20mg Tablets0.45 mg/20 mg · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $672.30for 90 tablets$7.47 per tablet | $5Pharmacy's estimate: 2–8 business days | $677.30 for 90 days= $677.30 for 90 daysincl. $5 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy I | DUAVIVE (sold outside the U.S. as Duavive)0.45 mg/20 mg · brand · Filled in CanadaProduct of Canada | $211.38per 28 tablets · 3 packs = $634.14$7.55 per tablet | FreeDelivery time not stated | $634.14 for 84 days= $679.44 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Duavee from Canada?
90-day cost = 90 tablets at the usual dose of 1 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
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Join to See PharmaciesAlready a member? Sign inDuavee price by strength
| Strength | Lowest brand90 days | Price per tablet |
|---|---|---|
| Duavee 0.45 mg/20 mg | $377.09 | $4.07 |
Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per tablet is for that lowest pack, before shipping. Prices checked Nov 11, 2026.
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90-day prices from 6 licensed pharmacies abroad shipping to the U.S.: $377.09 to $679.44, any strength, shipping included.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Duavee · Similar drugs · Uses · FAQ
Duavee (conjugated estrogens and bazedoxifene) treats menopause hot flashes and helps prevent bone loss after menopause. It comes as one 0.45/20 mg tablet a day, and no generic is sold in the U.S.
Duavee cost at a glance
- TrumpRx.gov price: from $30.30 for 30 tablets with the TrumpRx coupon, shown at retail pharmacies that dispense Duavee. It is an out-of-pocket (cash) price, and TrumpRx shows an original price of $202.00 (TrumpRx.gov, checked 2026-11-11).
- U.S. list price: $202.85 for a 30-tablet pack of Duavee, or $608.55 for 90 days. This is the maker's wholesale price before discounts (Texas DSHS).
- No generic Duavee in the U.S. Drugs@FDA lists Pfizer's Duavee (NDA 022247) as the only conjugated estrogens and bazedoxifene tablet (Drugs@FDA, checked 2026-11-11).
- Pfizer co-pay card: with private insurance, you may pay as little as $25 per prescription, with up to $110 off each Duavee fill and $1,440 a year. Not for Medicare, Medicaid or cash-paying patients (Pfizer terms).
- How we count: 1 tablet a day, the label's dose.
- From online pharmacies abroad: $377.09 to $679.44 for 90 days of brand Duavee, shipping included (checked Nov 11, 2026). With the TrumpRx coupon, 90 tablets in the U.S. work out to about $90.90.
How much does Duavee cost in the U.S.?
| If you have | What Duavee costs | Source |
|---|---|---|
| No insurance (list price) | $202.85 for 30 tablets of Duavee ($608.55 for 90 days). Pharmacies may charge more. | Texas DSHS 2026 WAC report |
| No insurance (TrumpRx coupon) | From $30.30 for 30 tablets with the TrumpRx coupon at retail pharmacies (original price $202.00). It's an out-of-pocket price; if you have insurance, TrumpRx suggests checking your copay first. | TrumpRx.gov |
| Private or employer insurance | Your copay depends on your plan. Pfizer's co-pay card may lower it to as little as $25 per prescription, with up to $110 off each fill and $1,440 a year. | Pfizer |
| Medicare Part D | Your plan sets the cost. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. The Pfizer co-pay card can't be used with Medicare. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Duavee lists at $202.85 for 30 tablets, about $6.76 a tablet (Texas DSHS). With the TrumpRx coupon, the same 30 tablets are listed from $30.30, about 85% less. List prices are what makers charge wholesalers; what a pharmacy charges you can be higher or lower.
Duavee cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Duavee depends on your plan's drug list. The Pfizer co-pay card can't be used with Medicare, but people with limited income can apply for Extra Help.
| Medicare Part D | What Duavee costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Duavee coupons and savings programs
eDrugSearch does not offer its own Duavee coupons. These are the real savings programs, run by the drug's maker and by Medicare:
- Pfizer MHT Co-pay Savings Card: for people with private insurance that covers Duavee. You may pay as little as $25 per prescription, with up to $110 off each Duavee fill and up to $1,440 a year. Not for Medicare, Medicaid, TRICARE, VA or other government programs, or for cash-paying patients. Offer expires December 31, 2026. Call 1-888-WMN-HLTH. (Pfizer terms)
- TrumpRx.gov coupon: an out-of-pocket price from $30.30 for 30 tablets of brand Duavee at retail pharmacies. If you have insurance, check your copay first. (TrumpRx.gov)
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Duavee?
No. No generic Duavee is sold in the U.S. Drugs@FDA lists Pfizer's Duavee (NDA 022247, approved October 3, 2013) as the only approved conjugated estrogens and bazedoxifene tablet, and the FDA drug listing shows only Duavee.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 0.45 mg/20 mg | No | — |
Outside the U.S.: Online pharmacies abroad may sell conjugated estrogens and bazedoxifene made for other markets. Packs made for other countries are not FDA-approved.
Source: Drugs@FDA: Duavee (NDA 022247). As of Nov 11, 2026.
Compare Duavee with similar drugs
Other menopause and bone-health medicines people often compare with Duavee. Premarin and Prempro also contain conjugated estrogens, Bijuva is another hormone option, and Evista and Osphena act on estrogen receptors without estrogen. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Premarinconjugated estrogens | Estrogen hormone therapy for menopause symptoms (conjugated estrogens tablets) | $66.18 for 90 days | See prices |
| Premproconjugated estrogens and medroxyprogesterone | Menopause hormone therapy (estrogen plus progestin) | $133.88 for 90 days | See prices |
| Bijuvaestradiol and progesterone | Menopause hormone therapy (estrogen plus progesterone) | $123.16 for 90 days | See prices |
| Evistaraloxifene | Osteoporosis medicine (estrogen agonist/antagonist) | $74.95 for 90 days | See prices |
| Osphenaospemifene | Menopause medicine for painful sex and vaginal dryness (estrogen agonist/antagonist) | $221.93 for 90 days | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Duavee used for?
Duavee combines conjugated estrogens with bazedoxifene, a medicine that blocks some effects of estrogen on the uterus. According to its FDA label (DailyMed), it is used in women who still have a uterus:
- To treat moderate to severe hot flashes and night sweats (vasomotor symptoms) caused by menopause.
- To help prevent bone loss (osteoporosis) after menopause.
Duavee comes as one strength, a 0.45/20 mg tablet (conjugated estrogens/bazedoxifene), taken once a day. The label says Duavee should be used for the shortest time that fits each woman's treatment goals and risks. Boxed warning: the label carries the FDA's strongest warning, about endometrial cancer, stroke, blood clots and probable dementia seen with estrogen therapy. Women taking Duavee should not take other estrogens. Your prescriber decides which medicine is right for you.
Is it safe to order Duavee from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Duavee, compare the TrumpRx.gov coupon price and Pfizer's co-pay card before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, the same Pfizer tablet is sold as Duavive (Health Canada).
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much does Duavee cost without insurance?
The U.S. list price is $202.85 for 30 tablets ($608.55 for 90 days), in the maker's 2026 price filing. TrumpRx.gov lists Duavee from $30.30 for 30 tablets with its coupon. Licensed pharmacies abroad charged from $377.09 for 90 days of brand Duavee in our latest check (Nov 11, 2026).
How much is Duavee on TrumpRx?
As of November 11, 2026, TrumpRx.gov lists brand Duavee from $30.30 for 30 tablets, down from an original price of $202.00. You show the coupon at a retail pharmacy. It's an out-of-pocket price, so if you have insurance, check your copay first.
Is there a Duavee coupon or savings card?
Yes. With private insurance, Pfizer's co-pay card may lower your cost to as little as $25 per prescription, with up to $110 off each Duavee fill and $1,440 a year; it expires December 31, 2026. The co-pay card can't be used with Medicare or Medicaid. People paying out of pocket can use the TrumpRx.gov coupon instead.
Is there a generic Duavee?
Not in the U.S. Drugs@FDA lists Pfizer's Duavee as the only approved conjugated estrogens and bazedoxifene tablet. Your prescriber decides which medicine is right for you.
How much does Duavee cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. The Pfizer co-pay card can't be used with Medicare, but people with limited income can apply for Extra Help.
What is the difference between Duavee and Premarin?
Premarin holds conjugated estrogens alone. Duavee adds bazedoxifene, which protects the lining of the uterus, so women with a uterus don't need a progestin with it. They are separate medicines with separate prices. Your prescriber decides which medicine is right for you.
Sources
- TrumpRx.gov: Duavee (from $30.30 for 30 tablets, original $202.00, checked 2026-11-11)
- Texas DSHS: 2026 annual WAC report (Duavee 30 tablets $202.85 (NDC 00008-1123-12))
- Pfizer MHT co-pay savings card terms (up to $110 per Duavee fill, $1,440 per year, commercial only, expires December 31, 2026, checked 2026-11-11)
- DUAVEE U.S. prescribing information (DailyMed) (Wyeth (Pfizer), label version 22 (effective April 28, 2026), incl. boxed warning)
- Drugs@FDA: Duavee (NDA 022247) (approved October 3, 2013; no generic applications)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.