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Osphena Price (ospemifene)
As of Nov 11, 2026, brand Osphena 60 mg costs from $221.93 for 90 days at licensed pharmacies abroad (ships from Canada; packs made for other countries are not FDA-approved), vs. $768 at the U.S. list price.
- Lowest U.S. online pharmacy price
- $5.73 per tablet$516.06 for 90 days (90 tablets), shipping included · FDA-approved brand Osphena 60 mg · ships within the U.S.
- Lowest international online pharmacy price
- $2.30 per tablet$221.93 for 90 days (90 tablets), shipping included · brand Osphena 60 mg, not FDA-approved · ships from Canada
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Osphena may cost less in the U.S.
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
The lowest price in our table is $221.93 (ships from Canada), shipping included. These programs can cost less:
- Osphena At Home (Duchesnay mail order): Duchesnay's Osphena At Home program lists brand Osphena for $190 for 90 tablets per prescription for people with no insurance or whose insurance doesn't cover Osphena. Your prescriber sends the prescription to PhilRx, which mails it to you with free home delivery. Call (844) 716-4663. Not for Medicare, Medicaid, TRICARE or other federal or state plans; a cash purchase won't count toward your Medicare or Medicaid plan or the $2,100 Medicare out-of-pocket cap. With private insurance, ask your plan whether a cash purchase counts toward your deductible. $190 for 90 days (Osphena savings)
We list these because they may save you money. No one pays us to include them. Prices and eligibility rules change, so confirm before you buy. Checked Nov 11, 2026.
Compare Osphena prices from licensed pharmacies
For comparison U.S. pharmacy list price: $768 for 90 days ($8.53 per tablet), brand Osphena before insurance. The prices below are from U.S. pharmacies that publish cash prices and from licensed online pharmacies outside the U.S.
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per tabletLicensed Canadian pharmacy A | Osphena (Ospemifene)60 mg · brand · Filled in CanadaProduct of Canada | $206.94for 90 tablets$2.30 per tablet | $14.99Delivery time not stated | $221.93 for 90 days= $221.93 for 90 daysSave 71%incl. $14.99 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy B | OSPHENA (UK pack, ships from Canada)60 mg · brand · Filled in CanadaProduct of UK | $258.31for 90 tablets$2.87 per tablet | FreeDelivery time not stated | $258.31 for 90 days= $258.31 for 90 daysSave 66%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | Senshio 60mg Tablet (UK/EU pack, ships from United Kingdom)60 mg · brand · Filled in United KingdomMaker listed by pharmacy: Maker not shown by pharmacyMade for UK/EU | $249.11for 84 tablets$2.97 per tablet | Fee not publishedDelivery time not stated | $249.11 for 84 days= $266.90 for 90 days+ shippingSave 65%Worked out from an 84-day orderChecked Nov 7 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy D | Senshio (UK/EU pack, ships from United Kingdom)60 mg · brand · Filled in United KingdomProduct of UK/EU | $259.99for 84 tablets$3.10 per tablet | Fee not publishedDelivery time not stated | $259.99 for 84 days= $278.56 for 90 days+ shippingSave 64%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | OSPHENA 60MG TABLET 90 (BRAND FROM CANADA)60 mg · brand · Filled in CanadaMaker listed by pharmacy: DUCHESNAY | $266for 90 tablets$2.96 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $280.95 for 90 days= $280.95 for 90 daysSave 63%incl. $14.95 shippingChecked Nov 7 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy B | OSPHENA60 mg · brand · Filled in UKProduct of UK | $374.99for 84 tablets$4.46 per tablet | FreeDelivery time not stated | $374.99 for 84 days= $401.78 for 90 daysSave 48%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy F | Osphena 60mg60 mg · brand · Filled in United KingdomMaker listed by pharmacy: Shionogi B.V. | $369for 84 tablets$4.39 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $378.95 for 84 days= $406.02 for 90 daysSave 47%Worked out from an 84-day orderChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed Canadian pharmacy G | Osphena60 mg · brand · Filled in CanadaMaker listed by pharmacy: Duchesnay Inc | $442.07for 90 tablets$4.91 per tablet | $9.95Pharmacy's estimate: 3–6 weeks | $452.02 for 90 days= $452.02 for 90 daysSave 41%incl. $9.95 shippingChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy H | Osphena, 60 MG Tablet (Prime member price)60 mg · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $172.02per 30 tablets · 3 packs = $516.06$5.73 per tablet | FreePharmacy's estimate: Usually next day | $516.06 for 90 days= $516.06 for 90 daysSave 33%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy H | Osphena, 60 MG Tablet (price without insurance)60 mg · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $302.40per 30 tablets · 3 packs = $907.20$10.08 per tablet | Fee not publishedPharmacy's estimate: Usually next day | $907.20 for 90 days= $907.20 for 90 days+ shippingincl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Osphena from Canada?
90-day cost = 90 tablets at the usual dose of 1 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
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90-day prices from 5 licensed pharmacies abroad shipping to the U.S.: $221.93 to $452.02, any strength, shipping included.
Jump to: Medicare · Maker savings · Generic Osphena · Similar drugs · Uses · FAQ
Osphena (ospemifene) 60 mg tablets, taken once a day, for painful sex or vaginal dryness due to menopause. No generic is sold in the U.S.
Osphena price by strength
| Strength | Lowest brand90 days | Price per tablet |
|---|---|---|
| Osphena 60 mg | $221.93 | $2.30 |
Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per tablet is for that lowest pack, before shipping. Prices checked Nov 11, 2026.
Cheapest ways to get Osphena 60 mg
The cheapest ways we found to get brand Osphena 60 mg (prices checked Nov 11, 2026). The lowest 90-day cost is shaded green.
| Way to buy | Cost | Details |
|---|---|---|
| Licensed online pharmacy abroad | $221.93 for 90 days | Brand Osphena 60 mg, ships from Canada, not FDA-approved (made for another country). Shipping included, checked Nov 11, 2026. See all prices |
| U.S. pharmacy cash price | $516.06 for 90 days | FDA-approved brand Osphena 60 mg, ships within the U.S. (no customs). Shipping included, checked Nov 11, 2026. See all prices |
| U.S. list price | $768 for 90 days | Brand Osphena before insurance. Pharmacies may charge more. |
| Medicare Part D | Depends on your plan | Your plan’s drug list and coverage phase set your cost. Medicare costs |
Costs abroad and at U.S. pharmacies are for one order closest to 90 days, shipping included, from the price table above. Programs set their own rules, so check the terms before you count on one.
How much does Osphena cost without insurance?
Without insurance, Osphena costs $256 for a 30-day supply at the U.S. list price, or about $768 for 90 days. Licensed pharmacies abroad charged from $221.93 for 90 days of brand Osphena 60 mg in our latest check (Nov 11, 2026), shipping included.
Osphena at home: $190 for 90 tablets per prescription by mail order (PhilRx), if you have no insurance or your insurance doesn't cover Osphena. Not for Medicare, Medicaid, TRICARE or other government plans (Duchesnay).
Osphena cost with Medicare
In 2026, a Medicare drug plan (Part D) can charge a deductible of up to $615, and once you've spent $2,100 out of pocket on covered drugs, you pay nothing more for covered drugs that year ($2,400 in 2027) (Medicare.gov). What you pay for Osphena depends on your plan's drug list and your coverage phase. If your income is limited, Extra Help lowers drug costs: in 2026 you pay no more than $5.10 for a generic and $12.65 for a brand-name drug, with income under $23,940 ($32,460 for a married couple) and resources under $18,090 ($36,100 for a couple) (CMS). The free Medicare Prescription Payment Plan spreads costs into monthly payments, but it doesn't lower the total.
| Medicare Part D | What Osphena costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026 ($2,400 in 2027), you pay nothing more for covered drugs that year. | Medicare.gov |
Osphena cost with insurance
With private or employer insurance, what you pay for Osphena depends on your plan's drug list, deductible and copay. Your copay depends on your plan. Duchesnay says you may pay as little as $35 for 30 tablets or $90 for 90 tablets through Osphena At Home, or as little as $45 for 30 tablets with the Osphena copay program (Duchesnay).
Medicaid: Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office (Medicaid.gov).
Osphena patient assistance program
We haven't found a patient assistance program for Osphena. In our checks of Duchesnay USA's own pages, we found no free-medicine program that lists Osphena. If you have Medicare and a limited income, Medicare Extra Help can lower what you pay for covered drugs.
Is there a generic Osphena?
Not sold. The FDA approved Hetero Labs' generic ospemifene 60 mg tablets on February 13, 2024, but the Orange Book lists them as discontinued, and the FDA drug listing shows only Duchesnay's Osphena tablets for sale.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 60 mg | No | — |
Outside the U.S.: Online pharmacies abroad may sell ospemifene made for other markets, for example Senshio in the U.K. and Europe. Packs that aren't FDA-approved are labeled that way in the price table.
Source: FDA Orange Book: ospemifene (NDA 203505, ANDA 215574). As of Oct 27, 2026.
Osphena FAQ
How much does Osphena cost without insurance?
The U.S. list price is $256 for 30 tablets of Osphena 60 mg, or $768 for 90 days (Duchesnay's early-2026 price before discounts, as reported to the Texas Department of State Health Services). Licensed pharmacies abroad charged from $221.93 for 90 days of brand Osphena 60 mg in our latest check (Nov 11, 2026). Duchesnay's Osphena At Home mail-order program lists $190 for 90 tablets for people with no insurance or whose insurance doesn't cover Osphena.
How much does Osphena cost with Medicare?
It depends on your Part D plan's drug list. In 2026, deductibles are capped at $615 and your out-of-pocket costs for covered drugs at $2,100. Duchesnay's savings offers can't be used by people enrolled in Medicare, but people with limited income can apply for Extra Help.
Is there a generic Osphena?
Not on sale in the U.S. The FDA approved a generic ospemifene from Hetero Labs in February 2024, but the FDA Orange Book lists it as discontinued. Only brand Osphena is listed for sale.
What is Osphena At Home?
It is Duchesnay's mail-order program, filled by PhilRx, with free home delivery. With commercial insurance, Duchesnay says you may pay as little as $35 for 30 tablets or $90 for 90 tablets. Without insurance, or if your insurance doesn't cover Osphena, the listed price is $190 for 90 tablets per prescription. Your prescriber sends the prescription. Call (844) 716-4663.
Is Osphena sold under another name?
In the U.K. and Europe, ospemifene is sold as Senshio. In Canada, Osphena is sold under the same name. Each country's packs are made for that market, and the price table shows the name and maker of each pack.
Is there a patient assistance program for Osphena?
We haven't found a patient assistance program for Osphena. In our checks of Duchesnay USA's own pages, we found no free-medicine program that lists Osphena. If you have Medicare and a limited income, Medicare Extra Help can lower what you pay for covered drugs.
Is Osphena an estrogen?
No. The FDA label calls Osphena an estrogen agonist/antagonist: it acts like estrogen in some tissues, including the lining of the uterus, and differently in others. Because it acts like estrogen in the uterus, its label carries a boxed warning about endometrial cancer, stroke and blood clots. Duchesnay describes it as non-hormonal. Your prescriber decides which medicine is right for you.
Savings programs from the maker
eDrugSearch does not offer its own Osphena coupons. These are the programs we could verify on Duchesnay's and the government's own sites:
- Osphena At Home (with private insurance): for people with commercial insurance: pay as little as $35 for 30 tablets or $90 for 90 tablets, mailed free by PhilRx. Your prescriber sends the prescription to the program. Not for Medicare, Medicaid, TRICARE or other federal or state plans. Call (844) 716-4663. (Osphena savings)
- Osphena Savings Card (retail pharmacy): for people with commercial insurance: pay as little as $45 for 30 tablets at participating retail pharmacies. Not for Medicare, Medicaid, TRICARE or other federal or state plans. Duchesnay may change or end the offer at any time. Call (347) 657-9766. (Osphena savings card)
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Compare Osphena with similar drugs
Other menopause medicines with price pages here: Estring (estradiol vaginal ring) and Premarin (conjugated estrogens tablets). They are different kinds of medicine, and your prescriber decides which medicine is right for you.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Estringestradiol | Vaginal estrogen for menopause symptoms (estradiol vaginal ring) | $138.95 for 90 days | See prices |
| Premarinconjugated estrogens | Estrogen hormone therapy for menopause symptoms (conjugated estrogens tablets) | $66.18 for 90 days | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Osphena used for?
Osphena (ospemifene) is an estrogen agonist/antagonist: it acts like estrogen in some tissues and differently in others. It is not an estrogen. According to its FDA label (DailyMed), it is used:
- To treat moderate to severe painful sex (dyspareunia), a symptom of vulvar and vaginal atrophy, due to menopause.
- To treat moderate to severe vaginal dryness, a symptom of vulvar and vaginal atrophy, due to menopause.
Boxed warning: the Osphena label carries the FDA's strongest warning, for endometrial cancer and cardiovascular disorders. It says Osphena acts like estrogen in the lining of the uterus (endometrium), and estrogen alone raises the risk of endometrial cancer in women who have a uterus. It also says estrogen-alone therapy raises the risk of stroke and deep vein thrombosis (blood clots in the legs), and it tells prescribers to prescribe Osphena for the shortest time that fits treatment goals and risks. Osphena comes as one strength, a 60 mg tablet taken once a day with food. Your prescriber decides which medicine is right for you.
Is it safe to order Osphena from Canada?
Many Americans do, but U.S. law and customs rules apply. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress declared in FD&C Act 804(j)(1), 21 U.S.C. 384(j)(1), that enforcement against individuals should focus on imports posing a significant threat to public health. You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, Osphena is sold under the same name; in the U.K. and Europe, ospemifene is sold as Senshio.
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Sources
- Texas DSHS: 2026 annual drug price (WAC) report (Osphena 30 tablets (NDC 55494-0580-30) $256.00, early 2026)
- Osphena savings programs (Duchesnay) (Osphena At Home and Savings Card, checked 2026-10-27)
- Osphena savings options and terms (Duchesnay PDF) (terms and conditions, Jan 2026)
- OSPHENA U.S. prescribing information (DailyMed)
- FDA Orange Book: Osphena (NDA 203505) (EOBZIP_2026_09)
- FDA Orange Book: ospemifene, Hetero Labs (ANDA 215574) (discontinued)
- FDA NDC Directory: ospemifene
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.