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Azulfidine Cost, Generic and Savings

Lowest U.S. online pharmacy price
$2.11 per tablet$764.60 for 90 days (360 tablets), shipping included · FDA-approved brand Azulfidine 500 mg · ships within the U.S.
Lowest international online pharmacy price
$0.19 per tablet$66.79 for 90 days (360 tablets), plus shipping (fee not published) · brand Azulfidine 500 mg, not FDA-approved · ships from New Zealand

FDA-approved generic sulfasalazine 500 mg from $109.31 for 90 days at U.S. pharmacies

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Prices checked Nov 12, 2026 · Page updated November 13, 2026 · By the eDrugSearch team · How we check pharmacies and prices

Quick answerAs of Nov 12, 2026, brand Azulfidine 500 mg costs from $129.04 for 90 days at online pharmacies abroad we compared, vs. $585.14 at the U.S. list price ($162.54 for 100 tablets). Generic sulfasalazine lists from $18.65 for 100.

Name check: This page is for regular Azulfidine tablets. Azulfidine EN-tabs (delayed-release tablets, also used for rheumatoid arthritis) release differently and aren't priced here.

Compare Azulfidine prices from licensed online pharmacies

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For comparison U.S. pharmacy list price: $585.15 for 90 days ($1.63 per tablet), brand Azulfidine before insurance. The prices below are from U.S. pharmacies that publish cash prices and from licensed online pharmacies outside the U.S.

PharmacyMedicationPriceShipping & deliveryTotal (90 days)Buy
Online pharmacy ASalazopyrin500 mg · brand · Filled in New ZealandProduct of New Zealand$55.66for 300 tablets$0.19 per tabletFee not publishedDelivery time not stated$55.66 for 75 days= $66.79 for 90 days+ shippingSave 89%Worked out from a 75-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy ASulfasalazine (UK/EU pack, ships from United Kingdom)Not FDA-approved500 mg · generic · Filled in United KingdomProduct of UK/EU$65.50for 336 tablets$0.19 per tabletFee not publishedDelivery time not stated$65.50 for 84 days= $70.18 for 90 days+ shippingSave 88%Worked out from an 84-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy BSulfasalazine (UK/EU pack, ships from United Kingdom)Not FDA-approved500 mg · generic · Filled in United KingdomProduct of UK/EU$72.99for 336 tablets$0.22 per tabletFee not publishedDelivery time not stated$72.99 for 84 days= $78.20 for 90 days+ shippingSave 87%Worked out from an 84-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy CGeneric Equivalent To Azulfidine 500mgNot FDA-approved500 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: IPCA laboratories$32.40per 180 tablets · 2 packs = $64.80$0.18 per tablet$14.95Pharmacy's estimate: 4–6 weeks$79.75 for 90 days= $79.75 for 90 daysSave 86%incl. $14.95 shippingChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy BSalazopyrin500 mg · brand · Filled in New ZealandProduct of New Zealand$66.99for 300 tablets$0.22 per tabletFee not publishedDelivery time not stated$66.99 for 75 days= $80.39 for 90 days+ shippingSave 86%Worked out from a 75-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Licensed U.S. pharmacy DSulfasalazine 500mg500 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 12, 2026$109.31for 360 tablets$0.30 per tabletFreePharmacy's estimate: 3–5 business days$109.31 for 90 days= $109.31 for 90 daysSave 81%incl. $0 shippingChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy ESulfasalazine (UK/EU pack, ships from United Kingdom)Not FDA-approved500 mg · generic · Filled in United KingdomProduct of UK/EU$104.33for 336 tablets$0.31 per tablet$9.95Delivery time not stated$114.28 for 84 days= $122.44 for 90 daysSave 79%Worked out from an 84-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy FGeneric Equivalent to Azulfidine 500mgNot FDA-approved500 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: IPCA laboratories$27.87per 90 tablets · 4 packs = $111.48$0.31 per tablet$14.95Pharmacy's estimate: 4–6 weeks$126.43 for 90 days= $126.43 for 90 daysSave 78%incl. $14.95 shippingChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy ESalazopyrin500 mg · brand · Filled in New ZealandProduct of New Zealand$97.58for 300 tablets$0.33 per tablet$9.95Delivery time not stated$107.53 for 75 days= $129.04 for 90 daysSave 78%Worked out from a 75-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy CGeneric Equivalent To Azulfidine 500mgNot FDA-approved500 mg · generic · Filled in United KingdomProduct of United Kingdom$35.27per 112 tablets · 3 packs = $105.81$0.31 per tablet$14.95Pharmacy's estimate: 4–6 weeks$120.76 for 84 days= $129.39 for 90 daysSave 78%Worked out from an 84-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy GGeneric Azulfidine 500mgNot FDA-approved500 mg · generic · Filled in IndiaMade for sale in India.Product of India$72.23per 180 tablets · 2 packs = $144.46$0.40 per tabletFee not publishedDelivery time not stated$144.46 for 90 days= $144.46 for 90 days+ shippingSave 75%incl. $0 shippingChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy HAzulfidine500 mg · brand · Filled in United KingdomMaker listed by pharmacy: Pfizer Inc$144for 336 tablets$0.43 per tablet$9.95Pharmacy's estimate: 4–6 weeks$153.95 for 84 days= $164.95 for 90 daysSave 72%Worked out from an 84-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy HAzulfidine500 mg · brand · Filled in CanadaMaker listed by pharmacy: Pfizer Inc$55per 100 tablets · 3 packs = $165$0.55 per tablet$9.95Pharmacy's estimate: 4–6 weeks$174.95 for 75 days= $209.94 for 90 daysSave 64%Worked out from a 75-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy CBrand Azulfidine 500mg500 mg · brand · Filled in New ZealandMaker listed by pharmacy: Pfizer$54per 100 tablets · 3 packs = $162$0.54 per tablet$14.95Pharmacy's estimate: 4–6 weeks$176.95 for 75 days= $212.34 for 90 daysSave 64%Worked out from a 75-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy FBrand Azulfidine 500mg500 mg · brand · Filled in New ZealandMaker listed by pharmacy: Pfizer$64.80per 100 tablets · 3 packs = $194.40$0.65 per tablet$14.95Pharmacy's estimate: 4–6 weeks$209.35 for 75 days= $251.22 for 90 daysSave 57%Worked out from a 75-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy ISalazopyrin500 mg · brand · Filled in CanadaMaker listed by pharmacy: Pfizer$203.20for 300 tablets$0.68 per tablet$14.95Pharmacy's estimate: 4–6 weeks$218.15 for 75 days= $261.78 for 90 daysSave 55%Worked out from a 75-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy GGeneric Azulfidine 500mg Tablet (Mfg.By Zydus Cadila)Not FDA-approved500 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Zydus Cadila$44.87per 60 tablets · 6 packs = $269.22$0.75 per tabletFee not publishedDelivery time not stated$269.22 for 90 days= $269.22 for 90 days+ shippingSave 54%incl. $0 shippingChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy JAZULFIDINE500 mg · brand · Filled in NEW ZEALANDMade for sale in NEW ZEALAND.Product of New Zealand$85.74per 100 tablets · 3 packs = $257.22$0.86 per tabletFreeDelivery time not stated$257.22 for 75 days= $308.66 for 90 daysSave 47%Worked out from a 75-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy KAZULFIDINE500 mg · brand · Filled in NEW ZEALANDMade for sale in NEW ZEALAND.Product of New Zealand$88.13per 100 tablets · 3 packs = $264.39$0.88 per tabletFreeDelivery time not stated$264.39 for 75 days= $317.27 for 90 daysSave 46%Worked out from a 75-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy ISalazopyrin500 mg · brand · Filled in New ZealandMaker listed by pharmacy: Pfizer$96.53per 100 tablets · 3 packs = $289.59$0.97 per tablet$14.95Pharmacy's estimate: 4–6 weeks$304.54 for 75 days= $365.45 for 90 daysSave 38%Worked out from a 75-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy GGeneric Azulfidine 500mg Tablet (Mfg.By Ipca Lab)Not FDA-approved500 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Ipca laboratories ltd$92.27per 90 tablets · 4 packs = $369.08$1.03 per tabletFee not publishedDelivery time not stated$369.08 for 90 days= $369.08 for 90 days+ shippingSave 37%incl. $0 shippingChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy ISulfasalazineNot FDA-approved500 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Ipca Laboratories Ltd$101.48per 90 tablets · 4 packs = $405.92$1.13 per tablet$14.95Pharmacy's estimate: 4–6 weeks$420.87 for 90 days= $420.87 for 90 daysSave 28%incl. $14.95 shippingChecked Nov 12See pharmacy (members) Members see the pharmacy
Licensed U.S. pharmacy LAzulfidine 500mg Tablets500 mg · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 12, 2026$63.30per 30 tablets · 12 packs = $759.60$2.11 per tablet$5Pharmacy's estimate: 2–8 business days$764.60 for 90 days= $764.60 for 90 daysincl. $5 shippingChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy MU.S. shipping limitedSulfasalazine (Generic)Not FDA-approved500 mg · generic · Filled in United KingdomProduct of United Kingdom$71per 112 tablets · 3 packs = $213$0.63 per tablet$14.95Pharmacy's estimate: 8–14 business days$227.95 for 84 days= $244.23 for 90 daysSave 58%Worked out from an 84-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy
Online pharmacy NAZULFIDINE 500MG TABLET 600 (SALAZOPYRIN BRAND FROM NEW ZEALAND)500 mg · brand · Filled in New ZealandProduct of New Zealand$186for 600 tablets$0.31 per tabletOver 3-month supply$14.95Pharmacy's estimate: 4–6 weeks$200.95 for 150 days= $120.57 for 90 daysSave 79%Worked out from a 150-day orderChecked Nov 12See pharmacy (members) Members see the pharmacy

Buying from a pharmacy outside the U.S.? Read Is it safe to order Azulfidine from Canada?

90-day cost = 360 tablets at the usual dose of 4 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 12, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.

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Azulfidine price by strength

StrengthLowest brand90 daysLowest generic abroad90 days, not FDA-approvedPrice per tablet
Azulfidine 500 mg$129.04$79.75$0.33 brand · $0.18 generic

Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per tablet is for that lowest pack, before shipping. Prices checked Nov 12, 2026.

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90-day prices from 7 licensed pharmacies abroad shipping to the U.S.: $79.75 to $420.87, any strength, shipping included.

Jump to: U.S. cost · Medicare · Coupons & savings · Generic Azulfidine · Similar drugs · Uses · FAQ

Azulfidine (sulfasalazine) 500 mg tablets for ulcerative colitis, taken several times a day. FDA-approved generics are sold in the U.S.

Other Ways to Pay for Azulfidine

How do you pay?

We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.

Other ways to pay, useful if you have insurance or Medicare:

  • TrumpRx.gov: The federal TrumpRx site lists brand Azulfidine 500 mg at $99.60 for 120 tablets (original price $199.20) and $149.40 for 180 (original $298.80), checked November 11, 2026. You print or save a coupon and show it at a retail pharmacy that carries Azulfidine. It can't be used with Medicare or Medicaid coverage, and a cash purchase won't count toward a Medicare plan's deductible or the $2,100 yearly cap. With private insurance, ask your plan whether a cash purchase counts toward your deductible. (TrumpRx.gov)

We list these because they may save you money. No one pays us to include them. Prices and eligibility rules change, so confirm before you buy. Checked Nov 12, 2026.

Azulfidine cost at a glance

  • U.S. list price: $162.54 for a bottle of 100 brand Azulfidine 500 mg tablets, about $1.63 a tablet ($487.72 for 300). At 4 tablets a day, that's $585.14 for 90 days (the maker's wholesale price before discounts; Texas DSHS).
  • TrumpRx: the federal TrumpRx site lists brand Azulfidine at $99.60 for 120 tablets and $149.40 for 180, with a coupon you show at a retail pharmacy. It can't be used with Medicare or Medicaid (TrumpRx.gov, checked 2026-11-11).
  • Generic Azulfidine is sold in the U.S., for less. Several companies sell FDA-approved generic sulfasalazine 500 mg tablets, rated equivalent to Azulfidine (FDA Orange Book). In the 2026 filing, Teva lists 100 tablets at $18.65 and Mylan at $21.35 (Texas DSHS).
  • How we count: 4 tablets a day (360 for 90 days), the label's adult maintenance dose of 2 g a day. Many people take more at first (3 to 4 g a day), so your cost may be higher.
  • From online pharmacies abroad: $129.04 to $365.45 for 90 days of brand Azulfidine 500 mg, shipping included (checked Nov 12, 2026). Packs made for other countries are not FDA-approved; outside the U.S., Azulfidine is often sold as Salazopyrin.

How much does Azulfidine cost in the U.S.?

If you haveWhat Azulfidine costsSource
No insurance (brand list price)$162.54 for 100 tablets of Azulfidine 500 mg ($487.72 for 300). Pharmacies may charge more.Texas DSHS 2026 WAC report
No insurance (TrumpRx coupon)$99.60 for 120 tablets or $149.40 for 180 of brand Azulfidine 500 mg with the TrumpRx coupon at a retail pharmacy (checked November 11, 2026). Not for Medicare or Medicaid.TrumpRx.gov
No insurance (generic)Generic sulfasalazine 500 mg lists from $18.65 for 100 tablets (Teva); Mylan lists $21.35. Ask your pharmacist for the cash price.Texas DSHS 2026 WAC report
Private or employer insuranceYour copay depends on your plan's drug list. Ask your plan or pharmacist what you'd pay for brand Azulfidine and for generic sulfasalazine.FDA Orange Book
Medicare Part DYour cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100.Medicare.gov
MedicaidYour state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office.Medicaid.gov

Brand Azulfidine lists at $162.54 for a bottle of 100 tablets in the U.S. (Texas DSHS). Generic sulfasalazine lists from $18.65 for 100 in the same filing. These are list prices (the maker's wholesale price before discounts); what a pharmacy charges can differ.

Azulfidine cost with Medicare in 2026

In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Azulfidine or generic sulfasalazine depends on your plan's drug list.

Medicare Part DWhat Azulfidine costsSource
Part D deductibleNo Medicare drug plan may have a deductible above $615 in 2026. Some plans have none.Medicare.gov
Yearly out-of-pocket capOnce your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year.Medicare.gov

Azulfidine coupons and savings programs

eDrugSearch does not offer its own Azulfidine coupons. eDrugSearch has no coupons of its own. If you have Medicare, these two programs can help with the cost of brand Azulfidine or generic sulfasalazine:

  • Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
  • Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)

Is there a generic Azulfidine?

Yes. The FDA has approved generic sulfasalazine 500 mg tablets from several makers, rated equivalent to Azulfidine. Generics have been sold since the 1970s.

StrengthU.S. genericMakersSince
500 mgYesChartwell, Teva (Watson), Nuvo, Rising and othersNov 12, 1973

Outside the U.S.: Online pharmacies abroad may also sell generic sulfasalazine made for other markets. Those packs are not FDA-approved, and the price table labels them that way.

Source: FDA Orange Book: sulfasalazine tablets. As of Nov 12, 2026.

Compare Azulfidine with similar drugs

Other ulcerative colitis medicines people often look up alongside Azulfidine, including Lialda, Asacol HD, Apriso and Pentasa (mesalamine), Dipentum, Uceris and Imuran. Prices are for each drug's lowest-priced strength.

DrugTypeLowest price we foundLink
LialdamesalamineUlcerative colitis medicine (aminosalicylate)$163.86 for 90 daysSee prices
Asacol HDmesalamine delayed-releaseUlcerative colitis medicine (aminosalicylate)$97.43 for 90 daysSee prices
AprisomesalamineUlcerative colitis medicine (aminosalicylate)Checking pricesSee prices
PentasamesalamineUlcerative colitis medicine (aminosalicylate)$365.13 for 90 daysSee prices
DipentumolsalazineUlcerative colitis medicine (aminosalicylate)$471.67 for 90 daysSee prices
UcerisbudesonideUlcerative colitis medicine (corticosteroid)From $6.41 per tabletSee prices
ImuranazathioprineImmunosuppressantFrom $0.30 per tabletSee prices

Lowest price from licensed pharmacies shipping to the U.S., any strength: 90-day prices include shipping; prices per unit are before shipping. Only your doctor can decide whether another drug is right for you.

What is Azulfidine used for?

Azulfidine is an aminosalicylate, a medicine that calms inflammation in the bowel. According to its FDA label (DailyMed), it is used:

  • To treat mild to moderate ulcerative colitis, and along with other treatment in severe ulcerative colitis.
  • To help keep ulcerative colitis in remission (longer time between flares).

The label's usual adult starting dose is 3 to 4 g a day (6 to 8 tablets) in evenly divided doses, then 2 g a day (4 tablets) to keep remission; some people start lower to avoid stomach upset. It isn't for people with intestinal or urinary blockage, porphyria, or allergy to sulfasalazine, sulfa drugs or salicylates. Your prescriber decides which medicine is right for you.

Is it safe to order Azulfidine from Canada?

Many Americans do, but U.S. law and customs rules apply, and for Azulfidine, compare the U.S. price of FDA-approved generic sulfasalazine and the TrumpRx coupon before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, Pfizer sells the same medicine as Salazopyrin; Health Canada lists Salazopyrin 500 mg tablets as marketed (Health Canada Drug Product Database, checked 2026-11-12).

Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.

Frequently asked questions

How much is Azulfidine without insurance?

The U.S. list price of brand Azulfidine is $162.54 for 100 tablets of 500 mg. The TrumpRx coupon price is $99.60 for 120 tablets (checked November 11, 2026), and generic sulfasalazine lists from $18.65 for 100. Online pharmacies abroad charged from $129.04 for 90 days of brand Azulfidine in our latest check (Nov 12, 2026).

Is there a generic Azulfidine?

Yes. FDA-approved generic sulfasalazine 500 mg tablets have been sold for decades, from several makers. Ask your pharmacist whether a generic can fill your prescription.

What's the difference between Azulfidine and Azulfidine EN-tabs?

Both contain sulfasalazine 500 mg. EN-tabs have a coating that delays release until the medicine passes the stomach, and they're also approved for rheumatoid arthritis. They're different products, so they aren't swapped without your prescriber.

Is Salazopyrin the same as Azulfidine?

Salazopyrin is the name Pfizer uses for sulfasalazine tablets in Canada and many other countries. Packs made for other countries are not FDA-approved.

How much does Azulfidine cost with Medicare?

It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help. The TrumpRx coupon can't be used with Medicare.

How many Azulfidine tablets do people take a day?

The label's usual adult maintenance dose is 2 g a day, or 4 tablets, often more at the start. Your prescription says how many you need.

Sources

eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.