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Angeliq Price, Coupons and Generic
- U.S. list price
- $598.41 for 90 days (90 tablets)The maker's price for brand Angeliq before discounts · Source: Texas DSHS 2026 WAC report
- Lowest international online pharmacy price
- Not available
Quick answerBrand Angeliq costs $186.17 per 28 tablets at the U.S. list price, either strength, about $598.40 for 90 days. A generic of the 0.5/1 mg strength is FDA-approved but not yet on sale in the U.S. Licensed pharmacies abroad we check had no U.S.-strength Angeliq (Nov 11, 2026).
Name check: Angeliq is for menopause symptoms in women with a uterus. It is not a birth control pill, even though one of its hormones is also used in some birth control pills.
Compare Angeliq prices from licensed online pharmacies
In our latest check, we found no licensed online pharmacy abroad selling this medicine.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Angeliq · Similar drugs · Uses · FAQ
Angeliq (drospirenone and estradiol) is a daily hormone pill for menopause symptoms, in 0.25/0.5 mg and 0.5/1 mg tablets, made by Bayer.
Angeliq cost at a glance
- U.S. list price: a 28-tablet pack of brand Angeliq lists at $186.17 in both strengths (the maker's wholesale price before discounts) (Texas DSHS). That works out to about $199.47 for 30 days and $598.40 for 90 days.
- Generic Angeliq: the FDA approved a generic of the 0.5/1 mg strength from Novast Labs on October 28, 2025 (Drugs@FDA). As of November 11, 2026, the FDA's drug listing shows only Bayer's brand on the U.S. market. No generic of the 0.25/0.5 mg strength is approved.
- How we count: 1 tablet a day. The label doses Angeliq once a day, every day, with no break between packs. Each pack holds 28 tablets.
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
- From online pharmacies abroad: the licensed pharmacies abroad we check had no Angeliq in U.S. strengths (checked Nov 11, 2026).
How much does Angeliq cost in the U.S.?
| If you have | What Angeliq costs | Source |
|---|---|---|
| No insurance (list price) | Brand Angeliq, 28 tablets: $186.17 for either strength (0.25/0.5 mg or 0.5/1 mg). Pharmacies may charge more. | Texas DSHS 2026 WAC report |
| Private or employer insurance | Your copay depends on your plan's drug list and whether it covers brand Angeliq. | Drugs@FDA |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Brand Angeliq lists at $186.17 for a 28-tablet pack, about $6.65 a tablet, in both strengths (Texas DSHS). Each pack is 28 days of treatment. List prices are what makers charge wholesalers; what a pharmacy charges you can differ.
Angeliq cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Angeliq depends on your plan's drug list.
| Medicare Part D | What Angeliq costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Angeliq coupons and savings programs
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
eDrugSearch does not offer its own Angeliq coupons. eDrugSearch has no coupons of its own. If you have Medicare, these two programs can help with the cost of Angeliq:
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Angeliq?
Not yet sold. The FDA approved Novast Labs' generic drospirenone and estradiol 0.5/1 mg tablets on October 28, 2025, rated equivalent to Angeliq 0.5/1 mg. But the FDA's drug listing shows only Bayer's brand on the U.S. market as of November 11, 2026. No generic of the 0.25/0.5 mg strength is approved.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 0.25/0.5 mg | No | — | |
| 0.5/1 mg | No | — |
Outside the U.S.: Online pharmacies abroad may sell drospirenone and estradiol made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: FDA Orange Book: drospirenone and estradiol products. As of Nov 11, 2026.
Compare Angeliq with similar drugs
Other menopause medicines people often compare with Angeliq. Each works in a different way, and your prescriber decides which medicine is right for you. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Premproconjugated estrogens and medroxyprogesterone | Menopause hormone therapy (estrogen plus progestin) | $133.88 for 90 days | See prices |
| Activellaestradiol and norethindrone acetate | Menopause hormone therapy (estrogen plus progestin) | $89.98 for 90 days | See prices |
| Bijuvaestradiol and progesterone | Menopause hormone therapy (estrogen plus progesterone) | $123.16 for 90 days | See prices |
| Premarinconjugated estrogens | Estrogen hormone therapy for menopause symptoms (conjugated estrogens tablets) | $66.18 for 90 days | See prices |
| Veozahfezolinetant | Non-hormonal medicine for menopause hot flashes (NK3 receptor antagonist) | $371.08 for 90 days | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Angeliq used for?
Angeliq combines an estrogen (estradiol) with a progestin (drospirenone). The progestin is there to protect the lining of the uterus. According to its FDA label (DailyMed), it is used in a woman with a uterus to treat:
- Moderate to severe hot flashes and night sweats (vasomotor symptoms) due to menopause (both strengths).
- Moderate to severe vaginal dryness, itching and burning (vulvar and vaginal atrophy) due to menopause (0.5/1 mg only). For these symptoms alone, the label says to consider vaginal products first.
Angeliq comes as 0.25/0.5 mg and 0.5/1 mg tablets taken once a day, every day. The label says to use hormone therapy at the lowest dose that works, for the shortest time that fits your goals, and to check in with your prescriber regularly. Boxed warning: the label carries the FDA's strongest warning. In a large study (the Women's Health Initiative), estrogen plus progestin raised the risk of stroke, heart attack, blood clots, breast cancer and probable dementia in women 65 and older. Your prescriber decides which medicine is right for you.
Is it safe to order Angeliq from Canada?
Many Americans do, but U.S. law and customs rules apply. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, Bayer sells Angeliq only as a 1 mg drospirenone/1 mg estradiol tablet, a strength that isn't sold in the U.S. (Health Canada), so Canadian packs don't match either U.S. strength.
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much is Angeliq without insurance?
The U.S. list price of brand Angeliq is $186.17 for a 28-tablet pack, in either strength, in the Texas 2026 drug price filing. That's about $598.40 for 90 days.
Is there a generic for Angeliq?
One is approved, but it doesn't appear to be on sale yet. The FDA approved Novast Labs' generic drospirenone and estradiol 0.5/1 mg on October 28, 2025. As of November 11, 2026, the FDA's drug listing shows only brand Angeliq on the U.S. market. The 0.25/0.5 mg strength has no approved generic.
Is there an Angeliq coupon or savings card?
eDrugSearch doesn't offer coupons of its own. If you have Medicare and limited income, Extra Help can lower what you pay, and the Medicare Prescription Payment Plan can spread costs over the year.
How much does Angeliq cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help.
Is Angeliq a birth control pill?
No. Angeliq is hormone therapy for menopause symptoms. Its label says it is for women with a uterus who have moderate to severe hot flashes or vaginal symptoms due to menopause.
Can I buy Angeliq from Canada?
Canada's Angeliq is a 1 mg/1 mg tablet, a strength that isn't sold in the U.S. Health Canada lists it as marketed by Bayer. Because it doesn't match either U.S. strength, this page leaves Canadian Angeliq packs out of the price table.
Does Angeliq have a boxed warning?
Yes. Like other estrogen plus progestin products, the label warns about higher risks of stroke, heart attack, blood clots, breast cancer and probable dementia seen in the Women's Health Initiative study. Talk with your prescriber about these risks.
Sources
- Texas DSHS: 2026 annual WAC report (Bayer Angeliq 28-tablet pack: $186.17 (NDC 50419-0482-03, 0.25/0.5 mg; 50419-0483-03, 0.5/1 mg) and $186.18 (-01); label carton = 28 tablets)
- ANGELIQ U.S. prescribing information (DailyMed) (Bayer HealthCare, label version 20 (effective March 2, 2026), incl. boxed warning)
- Drugs@FDA: Angeliq (NDA 021355) (approved September 28, 2005; 0.5/1 mg (TE AB) and 0.25/0.5 mg, prescription)
- Drugs@FDA: Novast Labs drospirenone and estradiol (ANDA 218031) (0.5/1 mg, approved October 28, 2025, TE AB)
- FDA NDC Directory: drospirenone and estradiol listings (only Bayer Angeliq (50419-482, 50419-483) listed; checked 2026-11-11)
- FDA Orange Book: drospirenone and estradiol products
- Health Canada Drug Product Database: Angeliq (DIN 02268825 (Bayer Inc), drospirenone 1 mg/estradiol 1 mg tablet, marketed since October 20, 2008; checked 2026-11-11)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.