Xtandi Price (enzalutamide)

Xtandi price by strength

Cheapest ways to get Xtandi 40 mg capsule

The cheapest ways we found to get brand Xtandi 40 mg capsule (prices checked Nov 5, 2026). The lowest 90-day cost is shaded green.

Costs abroad and at U.S. pharmacies are for one order closest to 90 days, shipping included, from the price table above. Programs set their own rules, so check the terms before you count on one.

How much does Xtandi cost without insurance?

Without insurance, Xtandi costs $15,352.94 for a 30-day supply at the U.S. list price, or about $46,058.82 for 90 days. Astellas patient assistance program: Xtandi at no cost for uninsured people who meet the program's rules. Call XTANDI Support Solutions at 1-855-898-2634 (XTANDI Support Solutions).

Xtandi cost with Medicare

In 2026, a Medicare drug plan (Part D) can charge a deductible of up to $615, and once you've spent $2,100 out of pocket on covered drugs, you pay nothing more for covered drugs that year ($2,400 in 2027) (Medicare.gov). What you pay for Xtandi depends on your plan's drug list and your coverage phase. Starting January 1, 2027, Medicare will pay a negotiated price of $7,004 for a 30-day supply of Xtandi (CMS, checked Oct 30, 2026). That's what Medicare will pay, not your copay. If your income is limited, Extra Help lowers drug costs: in 2026 you pay no more than $5.10 for a generic and $12.65 for a brand-name drug, with income under $23,940 ($32,460 for a married couple) and resources under $18,090 ($36,100 for a couple) (CMS). The free Medicare Prescription Payment Plan spreads costs into monthly payments, but it doesn't lower the total.

Xtandi cost with insurance

With private or employer insurance, what you pay for Xtandi depends on your plan's drug list, deductible and copay. Your copay depends on your plan. The XTANDI Patient Savings Program can lower it to as little as $0 per prescription, up to $7,000 a year (XTANDI.com).

Medicaid: Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office (Medicaid.gov).

Xtandi patient assistance program

Yes. Xtandi is offered through Astellas Patient Assistance Program, which can give the medicine at no cost to people who qualify. Who qualifies: Patients with no insurance coverage who meet the program's eligibility requirements can get Xtandi at no cost. How to apply: Call 1-855-898-2634 (1-855-8XTANDI), 8 AM to 8 PM ET, Monday to Friday, to see if you qualify. (Checked 2026-10-29.)

Xtandi FAQ

Brand vs. generic: cost for 90 days

Lowest in this comparison: Brand Xtandi, U.S. list price.

90 days = 360 40 mg units of 40 mg capsule. Generic sold abroad is not FDA-approved and is not in this box. Your price with insurance or Medicare depends on your plan.

Savings programs from the maker

eDrugSearch does not offer its own Xtandi coupons. We found no Astellas cash-price program or printable coupon for Xtandi in our latest check. These are the programs we could verify:

• XTANDI Patient Savings Program: for people with commercial (private or employer) prescription insurance: pay as little as $0 per prescription, with up to $7,000 in help per calendar year and no income requirement. Not for Medicare, Medicaid, VA, TRICARE or other government plans, and not for people paying cash. If your plan has a copay maximizer or accumulator program, help may be limited to $25 per claim. Call 1-855-898-2634. (XTANDI.com)
• Astellas Patient Assistance Program: free Xtandi for uninsured people who meet the program's eligibility rules. Astellas does not list the income limits online; call XTANDI Support Solutions at 1-855-898-2634 (Monday to Friday, 8 AM to 8 PM ET). (XTANDI.com)
• Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
• Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)

What is Xtandi used for?

Xtandi (enzalutamide) is an androgen receptor inhibitor. According to its FDA label (DailyMed), it is used to treat:

• Castration-resistant prostate cancer (CRPC).
• Metastatic castration-sensitive prostate cancer (mCSPC).
• Non-metastatic castration-sensitive prostate cancer with biochemical recurrence at high risk for metastasis (high-risk BCR).

Xtandi comes as 40 mg capsules and as 40 mg and 80 mg tablets. The label's usual dose is 160 mg once a day: four 40 mg capsules, four 40 mg tablets or two 80 mg tablets. Xtandi has no boxed warning and no REMS program in its FDA label. Astellas's XTANDI Support Solutions can arrange delivery through a specialty pharmacy (XTANDI support guide). Your prescriber decides which medicine is right for you.