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Generic Xtandi (enzalutamide) Price
No FDA-approved generic Xtandi is sold in the U.S. yet.
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Quick answerNo FDA-approved generic enzalutamide is sold in the U.S. yet. The FDA approved generic enzalutamide tablets in April 2026, but none is listed for sale in the U.S. As of Nov 5, 2026, licensed pharmacies abroad we compared charged from for 90 days (360 capsules) of generic enzalutamide 40 mg capsules, shipping included. This is generic enzalutamide made for sale in other countries, with the same active ingredient as Xtandi, listed by licensed pharmacies abroad. It is not FDA-approved, and you need a prescription.
Name check: Glenmark's 40 mg tablets were on backorder in our latest check, so the lowest price shown is for 40 mg capsules.
Compare generic Xtandi prices
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per 40 mg unitOnline pharmacy A | Generic Equivalent To Xtandi 40mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.40 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Glenmark | $124.80per 28 40 mg units · 13 packs = $1,622.40$4.46 per 40 mg unit | $14.95Pharmacy's estimate: 4–6 weeks | $1,637.35 for 91 days= $1,619.36 for 90 daysWorked out from a 91-day orderChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per 40 mg unitLicensed Canadian pharmacy B | EnzalutamideNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.40 mg · generic · Filled in CanadaMaker listed by pharmacy: AURO PHARMA INC | $600per 120 40 mg units · 3 packs = $1,800$5.00 per 40 mg unit | $9.95Pharmacy's estimate: 3–6 weeks | $1,809.95 for 90 days= $1,809.95 for 90 daysincl. $9.95 shippingChecked Nov 7 | See pharmacy (members) Members see the pharmacy |
| Lowest per 40 mg unitOnline pharmacy C | Enzalutamide 40mg CapsuleNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.40 mg · generic · Filled in CanadaMaker listed by pharmacy: Auro Pharma Inc. | $759.99per 120 40 mg units · 3 packs = $2,279.97$6.33 per 40 mg unit | FreePharmacy's estimate: 2–3 weeks | $2,279.97 for 90 days= $2,279.97 for 90 daysincl. $0 shippingChecked Nov 7 | See pharmacy (members) Members see the pharmacy |
| Lowest per 40 mg unitOnline pharmacy D | XTANDI 80MG CAPSULE 84 (GENERIC ENZALUTAMIDE FROM INDIA)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.80 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: DR REDDYS | $570per 84 40 mg units · 4 packs = $2,280$6.79 per 40 mg unit | $14.95Pharmacy's estimate: 4–6 weeks | $2,294.95 for 84 days= $2,458.88 for 90 daysWorked out from an 84-day orderChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per 40 mg unitOnline pharmacy E | Generic Equivalent To Xtandi 40mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.40 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Glenmark | $224.68per 28 40 mg units · 13 packs = $2,920.84$8.02 per 40 mg unit | $14.95Pharmacy's estimate: 4–6 weeks | $2,935.79 for 91 days= $2,903.53 for 90 daysWorked out from a 91-day orderChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per 40 mg unitOnline pharmacy F | Generic Equivalent To Xtandi 40mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.40 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Glenmark | $314.81per 28 40 mg units · 13 packs = $4,092.53$11.24 per 40 mg unit | $14.95Pharmacy's estimate: 4–6 weeks | $4,107.48 for 91 days= $4,062.34 for 90 daysWorked out from a 91-day orderChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Enzalutamide from Canada?
90-day cost = 360 40 mg units at the usual dose of 4 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 5, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout.
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90-day prices from 6 licensed pharmacies shipping to the U.S.: $1,619.36 to $4,062.34, any strength, shipping included.
Jump to: Brand vs. generic · U.S. prices · Insurance · Medicare · Maker savings · Who makes it · Brand or generic · Uses · FAQ
Generic Xtandi: enzalutamide 40 mg capsules and tablets made for sale in other countries, from licensed pharmacies abroad. Not FDA-approved. No FDA-approved generic enzalutamide is sold in the U.S. yet. Also sold as: Xtandi (brand, Astellas and Pfizer)
Enzalutamide price by strength
| Strength | Lowest generic abroad90 days, not FDA-approved | Price per 40 mg unit |
|---|---|---|
| Enzalutamide 40 mg | $1,619.36 | $4.46 generic |
| Enzalutamide 80 mg | $2,458.88 | $6.79 generic |
Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per 40 mg unit is for that lowest pack, before shipping. Prices checked Nov 5, 2026.
Enzalutamide names
- Brand name: Xtandi (Astellas and Pfizer)
- Generic name: enzalutamide
- Names in Canada: Xtandi, plus generics such as Apo-Enzalutamide, Auro-Enzalutamide, Jamp Enzalutamide and Reddy-Enzalutamide (Health Canada Drug Product Database, marketed products, checked Oct 29, 2026)
Enzalutamide packs made for other countries are not FDA-approved.
Who makes generic enzalutamide in the U.S.
No company sells FDA-approved generic enzalutamide in the U.S. yet. The FDA approved Sandoz's generic enzalutamide tablets (40 mg and 80 mg) on April 20, 2026, but no generic enzalutamide is listed for sale in FDA drug listing data as of October 23, 2026. Generic enzalutamide is sold in Canada and other countries.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 40 mg capsule | Approved, not sold | — | |
| 40 mg tablet | Approved, not sold | — | |
| 80 mg tablet | Approved, not sold | — |
Outside the U.S.: Licensed pharmacies abroad list generic enzalutamide made for sale in other countries, with the same active ingredient as Xtandi, from makers such as Auro Pharma (Canada) and Glenmark (India). These are not FDA-approved, and the price table labels them that way.
Source: FDA approval letter: Sandoz enzalutamide tablets (ANDA 216068). As of Oct 29, 2026.
Enzalutamide FAQ
How much does generic Xtandi cost?
No FDA-approved generic enzalutamide is sold in the U.S. yet. It is not FDA-approved. In the U.S., brand Xtandi costs $15,352.94 for a 30-day supply of brand Xtandi, any form (wholesale list price as of March 10, 2026). Pharmacies may charge more.
Is there a generic Xtandi in the U.S.?
Not yet. No FDA-approved generic enzalutamide is sold in the U.S. yet. The FDA approved generic enzalutamide tablets in April 2026, but none is listed for sale in the U.S. The generic name for Xtandi is enzalutamide.
Does Medicare cover generic enzalutamide?
No FDA-approved generic enzalutamide is sold in the U.S. yet. Medicare drug plans cover drugs on their own drug lists, so check how your plan covers brand Xtandi. In 2026, Part D deductibles are up to $615 and out-of-pocket costs for covered drugs are capped at $2,100 a year ($2,400 in 2027).
Is generic enzalutamide from abroad FDA-approved?
No. It is generic enzalutamide made for sale in other countries, with the same active ingredient as Xtandi, listed by licensed pharmacies abroad. It is not FDA-approved, and the price table labels it “Not FDA-approved.”
Who makes the generic enzalutamide sold abroad?
In our latest check, the pharmacies abroad we compared listed generic enzalutamide from Auro Pharma (Canada) and Glenmark (India). When a pharmacy doesn't name the maker, the price table says so.
Is enzalutamide the same as Xtandi?
Not in the FDA's sense. No FDA-approved generic Xtandi is sold in the U.S., so the FDA hasn't rated any generic equivalent to Xtandi. Generic enzalutamide sold abroad has the same active ingredient as Xtandi but is made for sale in other countries and is not FDA-approved.
Do I need a prescription for generic enzalutamide?
Yes. Licensed pharmacies, in the U.S. and abroad, need a valid prescription from your doctor. Never buy it from a website that does not ask for one.
Brand vs. generic: cost for 90 days
| Option | 90 days |
|---|---|
| Generic enzalutamide 40 mg capsule, U.S. pharmacy cash priceWe have not confirmed a U.S. pharmacy price yet | — |
| Brand Xtandi 40 mg capsule from licensed pharmacies abroadLowest price we found, shipping included, checked Nov 5, 2026 | — |
| Brand Xtandi, U.S. list priceBefore insurance; pharmacies may charge more | $46,058.82 |
Lowest in this comparison: Brand Xtandi, U.S. list price.
90 days = 360 40 mg units of 40 mg capsule. Generic sold abroad is not FDA-approved and is not in this box. Your price with insurance or Medicare depends on your plan.
Generic enzalutamide price in the U.S.
Enzalutamide cost at a glance
- No FDA-approved generic enzalutamide is sold in the U.S. yet. The FDA approved generic enzalutamide tablets in April 2026, but none is listed for sale in the U.S.
- From licensed pharmacies abroad: for 90 days (360 capsules) of generic enzalutamide 40 mg capsules, shipping included (checked Nov 5, 2026). Not FDA-approved.
- What it is: Generic enzalutamide made for sale in other countries, with the same active ingredient as Xtandi, listed by licensed pharmacies abroad. The price table labels every pack “Not FDA-approved.”
- Brand Xtandi in the U.S.: $15,352.94 for a 30-day supply of brand Xtandi, any form (wholesale list price as of March 10, 2026). Pharmacies may charge more. See the Xtandi page for savings programs.
- Prescription needed: licensed pharmacies need a valid prescription from your doctor.
- How we count: the usual dose is 160 mg once a day (four 40 mg capsules), so 90 days is 360 capsules.
How much does Enzalutamide cost in the U.S.?
| If you have | What Enzalutamide costs | Source |
|---|---|---|
| No insurance (brand Xtandi list price) | $15,352.94 for a 30-day supply of brand Xtandi, any form (wholesale list price as of March 10, 2026). Pharmacies may charge more. | Astellas/Pfizer price disclosure |
| Generic in the U.S. | No FDA-approved generic enzalutamide is sold in the U.S. yet. Ask your pharmacist if this changes. | FDA |
| Private or employer insurance | Your copay for brand Xtandi depends on your plan's drug list and tier. Maker savings programs are for brand Xtandi only (see the Xtandi page). | Your plan |
| Medicare Part D | Coverage and copay for brand Xtandi depend on your plan. Check plans with Medicare's Plan Finder. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
No FDA-approved generic enzalutamide is sold in the U.S. yet. The prices in the table above are for generic enzalutamide made for sale in other countries, with the same active ingredient as Xtandi, listed by licensed pharmacies abroad, and they are not FDA-approved.
Enzalutamide cost with Medicare in 2026
Each Part D plan has its own list of covered drugs and copays (Medicare Plan Finder). No FDA-approved generic enzalutamide is sold in the U.S. yet. Check how your plan covers brand Xtandi; the Xtandi page has Medicare details. In 2026, Part D plans can have a yearly deductible of up to $615, and your out-of-pocket costs for covered drugs are capped at $2,100 a year ($2,400 in 2027) (Medicare.gov).
| Medicare Part D | What Enzalutamide costs | Source |
|---|---|---|
| Part D deductible (2026) | Up to $615 a year, depending on your plan | Medicare.gov |
| Yearly out-of-pocket cap (2026) | $2,100 for covered Part D drugs ($2,400 in 2027) | Medicare.gov |
| Which plans cover Xtandi | Search your plan's drug list with your ZIP code | Medicare Plan Finder |
Savings programs from the maker
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
eDrugSearch does not offer its own Enzalutamide coupons. Maker savings and assistance programs are for brand Xtandi only, not generic enzalutamide from abroad (see the Xtandi page). eDrugSearch has no coupons of its own. These programs can lower prescription costs if you have Medicare:
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
When people choose brand Xtandi
Some people get brand Xtandi instead of generic enzalutamide. Common reasons:
- In the U.S., enzalutamide is sold only as brand Xtandi. The Xtandi page shows U.S. prices, prices abroad and the maker's savings programs.
- Some insurance and Medicare drug plans cover brand Xtandi. Your plan's drug list shows whether it does and what you pay.
Your prescriber decides which medicine is right for you.
Compare prices for your other medicines
- Xtandi prices from $1,619.36 for 90 days
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength.
What is Enzalutamide used for?
Enzalutamide is the active ingredient in Xtandi. Xtandi (enzalutamide) is an androgen receptor inhibitor. According to its FDA label (DailyMed), it is used to treat:
- Castration-resistant prostate cancer (CRPC).
- Metastatic castration-sensitive prostate cancer (mCSPC).
- Non-metastatic castration-sensitive prostate cancer with biochemical recurrence at high risk for metastasis (high-risk BCR).
Xtandi comes as 40 mg capsules and as 40 mg and 80 mg tablets. The label's usual dose is 160 mg once a day: four 40 mg capsules, four 40 mg tablets or two 80 mg tablets. Xtandi has no boxed warning and no REMS program in its FDA label. Astellas's XTANDI Support Solutions can arrange delivery through a specialty pharmacy (XTANDI support guide). Your prescriber decides which medicine is right for you.
Is it safe to order Enzalutamide from Canada?
Many Americans do, but U.S. law and customs rules apply. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress declared in FD&C Act 804(j)(1), 21 U.S.C. 384(j)(1), that enforcement against individuals should focus on imports posing a significant threat to public health. You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. Generic enzalutamide sold by pharmacies abroad is not FDA-approved. No FDA-approved generic enzalutamide is sold in the U.S. yet.
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Sources
- FDA approval letter: Sandoz enzalutamide tablets (ANDA 216068) (approved April 20, 2026)
- FDA Orange Book: enzalutamide products
- FDA NDC Directory: enzalutamide listings (checked Oct 29, 2026)
- XTANDI prescribing information (DailyMed)
- Astellas/Pfizer price disclosure: brand Xtandi list price
- Medicare.gov: costs in drug plans (2026 deductible up to $615; out-of-pocket cap $2,100 in 2026, $2,400 in 2027)
- Medicare Plan Finder
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicaid.gov: cost sharing
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.