Home › Drug Prices › Samsca
Samsca Price, Generic and Savings
- Lowest price per tablet at U.S. online pharmacies
- $53.23 per tabletIn a pack of 60 tablets for $3,194 (before shipping) · FDA-approved generic tolvaptan 15 mg · ships within the U.S.
- Lowest price per tablet at online pharmacies abroad
- $116.16 per tabletIn a pack of 30 tablets for $3,484.66 (before shipping) · brand Samsca 15 mg, not FDA-approved · ships from Canada
FDA-approved generic tolvaptan 15 mg from $53.23 per tablet at U.S. pharmacies
See all Samsca pricesSign in or get a free account, and we'll bring you back here. Free accounts: 2 alerts · Members: unlimited
Quick answerAs of Nov 12, 2026, brand Samsca 15 mg costs from $116.16 per tablet at online pharmacies abroad we compared, before shipping. In the U.S., brand Samsca 15 mg lists at $5,201.97 for 10 tablets, about $520.20 each; generic tolvaptan 15 mg lists from $600.00 for 10.
Name check: Samsca is not the same as Jynarque or Jinarc, other tolvaptan tablets for kidney disease. The Samsca label says not to use Samsca for that.
Compare Samsca prices from licensed online pharmacies
| Pharmacy | Medication | Pack | Price per unit | Pack price | Shipping & delivery | Total with shipping | Buy |
|---|---|---|---|---|---|---|---|
| Lowest price per unitOnline pharmacy A | TolvaptanNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.15 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Zydus | 90 tablets2 other pack sizes
| $2.10 per tablet | $189.01 | $14.95Pharmacy's estimate: 4–6 weeks | $203.96Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitLicensed U.S. pharmacy B | Tolvaptan 30mg Tablet30 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 12, 2026 | 60 tablets11 other pack sizes
| $48.83 per tablet | $2,930 | FreePharmacy's estimate: 3–5 business days | $2,930Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitLicensed U.S. pharmacy B | Tolvaptan 15mg Tablet15 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 12, 2026 | 60 tablets11 other pack sizes
| $53.23 per tablet | $3,194 | FreePharmacy's estimate: 3–5 business days | $3,194Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy C | Generic Samsca 15mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.15 mg · generic · Filled in IndiaMade for sale in India.Product of India | 48 tablets4 other pack sizes
| $76.62 per tablet | $3,677.70 | Fee not publishedDelivery time not stated | $3,677.70+ shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy C | Generic Samsca 30mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.30 mg · generic · Filled in IndiaMade for sale in India.Product of India | 20 tablets4 other pack sizes
| $86.61 per tablet | $1,732.25 | Fee not publishedDelivery time not stated | $1,732.25+ shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy A | Samsca30 mg · brand · Filled in CanadaMaker listed by pharmacy: Otsuka Pharmaceuticals | 30 tablets2 other pack sizes
| $116.15 per tablet | $3,484.41 | $14.95Pharmacy's estimate: 4–6 weeks | $3,499.36Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy A | Samsca15 mg · brand · Filled in CanadaMaker listed by pharmacy: Otsuka Pharmaceuticals | 30 tablets2 other pack sizes
| $116.16 per tablet | $3,484.66 | $14.95Pharmacy's estimate: 4–6 weeks | $3,499.61Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy D | SAMSCA 15MG TABLET 30 (BRAND FROM UK)15 mg · brand · Filled in UKProduct of UK | 30 tablets | $163.33 per tablet | $4,900 | $14.95Pharmacy's estimate: 4–6 weeks | $4,914.95Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy E | SAMSCA15 mg · brand · Filled in UKProduct of UK | 30 tablets | $222.56 per tablet | $6,676.86 | FreeDelivery time not stated | $6,676.86Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Samsca from Canada?
| Strength | Lowest brandper unit, before shipping | Lowest generic abroadper unit, not FDA-approved |
|---|---|---|
| Samsca 15 mg | $116.16 per tablet | $2.10 per tablet |
| Samsca 30 mg | $116.15 per tablet | — |
Each row is one product from one pharmacy, shown in the pack size with the lowest price per unit; its other pack sizes are listed under “other pack sizes”. Price per unit = the pack price divided by the units in the pack, before shipping; we sort by it and don't assume how long a pack lasts. Total with shipping = the pack price plus the pharmacy's shipping fee for one order. Prices checked Nov 12, 2026 on each pharmacy's website, in U.S. dollars (converted when a pharmacy prices in Canadian dollars). The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
Members see pharmacy names, ratings, visit links and price-drop alerts.
Join to See PharmaciesAlready a member? Sign inGet an email if the price drops. Free accounts can watch 2 medications. Sign in to watch this price
Prices per tablet from 3 licensed pharmacies abroad shipping to the U.S.: $2.10 to $222.56, any strength, before shipping.
Jump to: U.S. cost · Medicare · Maker savings · Generic Samsca · Uses · FAQ
Samsca (tolvaptan) 15 mg and 30 mg tablets for low blood sodium, started in a hospital. FDA-approved generics are sold in the U.S.
Samsca cost at a glance
- U.S. list price: $5,201.97 for a blister of 10 brand Samsca 15 mg tablets, about $520.20 a tablet, and $5,396.43 for 10 x 30 mg. That's Otsuka's wholesale price before discounts (Texas DSHS).
- Generic Samsca is sold in the U.S., for much less. Several companies sell FDA-approved generic tolvaptan 15 mg and 30 mg tablets, rated equivalent to Samsca (FDA Orange Book). In the 2026 filing, Annora, Novadoz and Par list 10 tablets of 15 mg at $600.00 (Texas DSHS).
- How we compare: per tablet. The label starts at 15 mg once a day and raises it as needed, for no more than 30 days, so we list each pharmacy's packs as sold and compare the price per tablet.
- From online pharmacies abroad: $116.16 to $222.56 per tablet of brand Samsca 15 mg, before shipping (checked Nov 12, 2026). Packs made for other countries are not FDA-approved.
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
How much does Samsca cost in the U.S.?
| If you have | What Samsca costs | Source |
|---|---|---|
| No insurance (brand list price) | $5,201.97 for 10 tablets of Samsca 15 mg; $5,396.43 for 10 x 30 mg. Pharmacies may charge more. | Texas DSHS 2026 WAC report |
| No insurance (generic) | Generic tolvaptan 15 mg lists from $600.00 for 10 tablets (Annora, Novadoz, Par). Ask your pharmacist for the cash price. | Texas DSHS 2026 WAC report |
| Private or employer insurance | Your copay depends on your plan's drug list. Ask your plan or pharmacist what you'd pay for brand Samsca and for generic tolvaptan. | FDA Orange Book |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Brand Samsca lists at $5,201.97 for 10 tablets of 15 mg in the U.S. (Texas DSHS). The same filing lists FDA-approved generic tolvaptan from $600.00 for 10 x 15 mg. These are list prices; what a pharmacy charges can differ.
Samsca cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Samsca or generic tolvaptan depends on your plan's drug list.
| Medicare Part D | What Samsca costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Savings programs from the maker
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
Checking more than one medicine? Use the free Medicare Drug Cost Check.
eDrugSearch does not offer its own Samsca coupons. eDrugSearch has no coupons of its own. If you have Medicare, these two programs can help with the cost of Samsca:
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Samsca?
Yes. The FDA has approved generic tolvaptan 15 mg and 30 mg tablets from several makers, rated equivalent to Samsca. The first were approved on May 19, 2020.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 15 mg | Yes | Apotex, Alkem, Hetero, PH Health, MSN and others | May 19, 2020 |
| 30 mg | Yes | Apotex, Alkem, Hetero, PH Health, MSN and others | May 19, 2020 |
Outside the U.S.: Online pharmacies abroad may sell generic tolvaptan made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: Drugs@FDA: tolvaptan generics. As of Nov 14, 2026.
What is Samsca used for?
Samsca (tolvaptan) is a vasopressin V2-receptor antagonist, a medicine that helps the kidneys pass extra water so blood sodium rises. According to its FDA label (DailyMed), it is used:
- To treat clinically significant low blood sodium (hyponatremia) in people with normal or high body fluid, including people with heart failure or SIADH.
The label says Samsca is started and restarted only in a hospital where sodium can be checked closely, at 15 mg once a day, raised to 30 mg and up to 60 mg if needed, and not used for more than 30 days because of liver injury risk. It has a boxed warning about raising sodium too fast and says it isn't for kidney disease (ADPKD). Your prescriber decides which medicine is right for you.
Is it safe to order Samsca from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Samsca, the label says it's started in a hospital and used for no more than 30 days, so ordering by mail rarely fits. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, Samsca 15 mg and 30 mg from Otsuka are listed as marketed (Health Canada Drug Product Database, checked 2026-11-14).
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much is Samsca without insurance?
Brand Samsca 15 mg lists at $5,201.97 for 10 tablets in the U.S., about $520.20 each; generic tolvaptan 15 mg lists from $600.00 for 10. Online pharmacies abroad charged from $116.16 per tablet for brand Samsca 15 mg in our latest check (Nov 12, 2026), before shipping.
Is there a generic Samsca?
Yes. Generic tolvaptan 15 mg and 30 mg tablets have been FDA-approved since 2020, from several makers. Ask your pharmacist whether a generic can fill your prescription.
Is Samsca the same as Jynarque?
Both contain tolvaptan, but Jynarque is a different product for a kidney disease (ADPKD), with its own doses. The Samsca label says Samsca isn't for ADPKD.
How much does Samsca cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help.
Sources
- Samsca U.S. prescribing information (DailyMed) (Otsuka label, version 23, effective 2026-05-07: hypervolemic/euvolemic hyponatremia; start 15 mg daily in hospital, up to 60 mg; max 30 days; boxed warning; blisters of 10)
- Drugs@FDA: Samsca (NDA 022275) (approved May 19, 2009; 15 and 30 mg Prescription AB1; 60 mg discontinued (not for safety reasons))
- Drugs@FDA: tolvaptan generics (Apotex and Alkem 2020-05-19; Hetero 2021; PH Health 2022; MSN 2023 and later)
- FDA Orange Book: tolvaptan tablets
- FDA NDC Directory: Samsca (59148-020-50 (15 mg x 10), 59148-021-50 (30 mg x 10), Otsuka, active; checked 2026-11-14)
- Texas DSHS 2026 WAC report: Samsca and generics (Otsuka Samsca 15mg 59148002050 (10) Trade $5,201.97; 30mg 59148002150 (10) $5,396.43; Annora 31722086803, Novadoz 72205013011, Par 49884076854 (15 mg x 10) $600.00)
- Health Canada Drug Product Database: Samsca (DINs 02370468 (15 mg), 02370476 (30 mg), Otsuka, Marketed)
- Texas DSHS: 2026 annual WAC report
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.