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Rytary Cost, Coupons and Generic
- Lowest price per capsule at U.S. online pharmacies
- $4.82 per capsuleIn a pack of 90 capsules for $433.80 (before shipping) · FDA-approved brand Rytary 48.75 mg/195 mg · ships within the U.S.
- Lowest price per capsule at online pharmacies abroad
- Not available
FDA-approved generic carbidopa and levodopa extended-release 48.75 mg/195 mg from $2.68 per capsule at U.S. pharmacies
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Quick answerAn authorized generic is sold in the U.S., and Amneal offers a co-pay card.
Name check: Crexont, Sinemet and other carbidopa-levodopa products are not interchangeable with Rytary dose for dose, so their prices are not mixed in here.
Compare Rytary prices from licensed online pharmacies
| Pharmacy | Medication | Pack | Price per unit | Pack price | Shipping & delivery | Total with shipping | Buy |
|---|---|---|---|---|---|---|---|
| Lowest price per unitLicensed U.S. pharmacy A | Carbidopa-Levodopa ER 48.75.-195mg Capsules48.75 mg/195 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | 90 capsules2 other pack sizes
| $2.68 per capsule | $241.20 | $5Pharmacy's estimate: 2–8 business days | $246.20Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitLicensed U.S. pharmacy A | Rytary 48.75-195mg Capsule48.75 mg/195 mg · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | 90 capsules2 other pack sizes
| $4.82 per capsule | $433.80 | $5Pharmacy's estimate: 2–8 business days | $438.80Checked Nov 11 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Rytary from Canada?
Each row is one product from one pharmacy, shown in the pack size with the lowest price per unit; its other pack sizes are listed under “other pack sizes”. Price per unit = the pack price divided by the units in the pack, before shipping; we sort by it and don't assume how long a pack lasts. Total with shipping = the pack price plus the pharmacy's shipping fee for one order. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars (converted when a pharmacy prices in Canadian dollars). The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, plus its standard shipping; no insurance or discount cards.
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Jump to: U.S. cost · Medicare · Coupons & savings · Generic Rytary · Similar drugs · Uses · FAQ
Rytary (carbidopa and levodopa) extended-release capsules for Parkinson's disease, in four strengths. An authorized generic is now sold in the U.S.
Rytary cost at a glance
- U.S. list price: $415.48 for a bottle of 100 capsules of brand Rytary in the three lower strengths, and $522.08 for 100 capsules of 61.25 mg/245 mg (the maker's wholesale price before discounts) (Texas DSHS). That's about $4.15 a capsule for the three lower strengths.
- A generic Rytary is sold in the U.S. Zydus sells an authorized generic, made under Rytary's own FDA approval, listed as on the market since October 20, 2025 (FDA drug listing). Its list price is $358.98 for 100 capsules ($451.08 for the top strength) (Texas DSHS). The FDA also approved a generic from Actavis (Teva) on November 2, 2026.
- Co-pay card: with commercial insurance, you may pay as little as $25 for your first Rytary prescription each month. Amneal covers up to $100 per fill. Not for Medicare or Medicaid (Amneal).
- How we compare: Rytary doses vary a lot from person to person. The label's starting schedule is one capsule three times a day, and many people take more. We list each pharmacy's packs as sold and compare the price per capsule.
- The U.S. list price works out to about $4.15 a capsule.
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
How much does Rytary cost in the U.S.?
| If you have | What Rytary costs | Source |
|---|---|---|
| No insurance (list price) | $415.48 for 100 capsules of brand Rytary 23.75 mg/95 mg, 36.25 mg/145 mg or 48.75 mg/195 mg; $522.08 for 100 capsules of 61.25 mg/245 mg. That is about $4.15 a capsule for the three lower strengths. Pharmacies may charge more. | Texas DSHS 2026 WAC report |
| No insurance (authorized generic) | Zydus's authorized generic carbidopa and levodopa extended-release capsules list at $358.98 for 100 capsules in the three lower strengths and $451.08 for 61.25 mg/245 mg. Ask your pharmacist for the cash price. | Texas DSHS 2026 WAC report |
| Private or employer insurance | Your copay depends on your plan. With the Rytary Co-Pay Savings Card, eligible people with commercial insurance may pay as little as $25 for the first prescription each month; Amneal covers up to $100 per fill. | Amneal |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Brand Rytary is sold in the U.S. in bottles of 100 capsules, listed at $415.48 for the three lower strengths and $522.08 for 61.25 mg/245 mg (Texas DSHS). That's about $4.15 a capsule for the lower strengths. How much a month costs depends on how many capsules you take: at 3 a day, 30 days takes 90 capsules (about $373.93), and at 6 a day it takes 180 (about $747.86). Zydus's authorized generic lists about 14% lower, at $358.98 for 100 capsules.
Rytary cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for brand Rytary or its generic depends on your plan's drug list. The Rytary Co-Pay Savings Card can't be used with Medicare.
| Medicare Part D | What Rytary costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Rytary coupons and savings programs
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
Checking more than one medicine? Use the free Medicare Drug Cost Check.
eDrugSearch does not offer its own Rytary coupons. eDrugSearch doesn't offer coupons of its own. These are the programs we could verify:
- Rytary Co-Pay Savings Card: if you have commercial insurance, you may pay as little as $25 for your first Rytary prescription each month. Amneal covers up to $100 per fill, for up to 3 fills a month, and a second or third fill in the same 30 days may cost as little as $0. Not valid for prescriptions paid for by Medicare, Medicaid or other federal or state programs. Sign up at MyRYTARYcopay.com or call 1-844-467-2928. The card is only valid while you have private insurance. (Amneal (Rytary co-pay flyer))
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Rytary?
Yes. Zydus sells an authorized generic of Rytary (made under Rytary's own FDA approval) in all four strengths, listed as on the market since October 20, 2025. The FDA also approved a generic from Actavis (a Teva company) on November 2, 2026, rated equivalent to Rytary; we found no FDA listing showing it on the market yet.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 23.75 mg/95 mg | Yes | Zydus (authorized generic); Actavis/Teva (approved November 2, 2026) | Oct 20, 2025 |
| 36.25 mg/145 mg | Yes | Zydus (authorized generic); Actavis/Teva (approved November 2, 2026) | Oct 20, 2025 |
| 48.75 mg/195 mg | Yes | Zydus (authorized generic); Actavis/Teva (approved November 2, 2026) | Oct 20, 2025 |
| 61.25 mg/245 mg | Yes | Zydus (authorized generic); Actavis/Teva (approved November 2, 2026) | Oct 20, 2025 |
Outside the U.S.: We know of no licensed pharmacy abroad that sells a generic of Rytary's extended-release capsules. Any pack made for another country is not FDA-approved, and the price table labels it that way.
Source: FDA Orange Book: carbidopa and levodopa products. As of Nov 11, 2026.
Compare Rytary with similar drugs
Mirapex ER (pramipexole) is another Parkinson's disease medicine. It works in a different way from carbidopa and levodopa. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Mirapex ERpramipexole extended-release | Parkinson's disease medicine (dopamine agonist) | From $0.56 per tablet | See prices |
Lowest price per unit, before shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Rytary used for?
Rytary combines carbidopa and levodopa in an extended-release capsule. Levodopa is thought to turn into dopamine in the brain, and carbidopa helps more levodopa get there. According to its FDA label (DailyMed), Rytary is used to treat:
- Parkinson's disease.
- Post-encephalitic parkinsonism (Parkinson-like symptoms after brain inflammation).
- Parkinsonism that may follow carbon monoxide or manganese poisoning.
Rytary comes in four strengths. For people new to levodopa, the label's starting dose is one 23.75 mg/95 mg capsule three times a day, which may go up to one 36.25 mg/145 mg capsule three times a day on day 4. Many people need more, up to the label's top dose of 612.5 mg/2,450 mg a day. Capsules shouldn't be chewed, divided or crushed. Rytary must not be taken with nonselective MAO inhibitors. The label warns that people may fall asleep during daily activities or have hallucinations or strong, hard-to-control urges, and that the dose shouldn't be stopped or cut suddenly. Your prescriber decides which medicine is right for you.
Is it safe to order Rytary from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Rytary, compare the Rytary co-pay card and the U.S. price of the authorized generic before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. Health Canada's drug database lists no product named Rytary (Health Canada), so we don't expect Canadian packs.
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much does Rytary cost without insurance?
The U.S. list price is $415.48 for 100 capsules of brand Rytary in the three lower strengths and $522.08 for 100 capsules of 61.25 mg/245 mg, in the Texas 2026 drug price filing. That's about $4.15 a capsule.
Is there a generic for Rytary?
Yes. Zydus sells an authorized generic (the same medicine without the brand name), listed as on the market since October 20, 2025. The FDA also approved a generic from Actavis, a Teva company, on November 2, 2026. Ask your pharmacist whether a generic can fill your prescription.
How much does generic Rytary cost?
In the Texas 2026 drug price filing, Zydus's authorized generic lists at $358.98 for 100 capsules in the three lower strengths and $451.08 for 100 capsules of 61.25 mg/245 mg. These are list prices, so what a pharmacy charges can differ. Ask your pharmacist for the cash price.
Is there a Rytary savings card?
Yes, for people with commercial insurance. With the Rytary Co-Pay Savings Card you may pay as little as $25 for your first prescription each month, and Amneal covers up to $100 per fill. It isn't valid with Medicare, Medicaid or other government programs. Call 1-844-467-2928.
How much does Rytary cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. The Rytary co-pay card can't be used with Medicare, but people with limited income can apply for Extra Help.
Why does my monthly Rytary cost differ from the price shown here?
Because the number of capsules varies a lot from person to person, we compare the price per capsule instead of a monthly total. If you take 6 capsules a day, you need twice as many as someone who takes 3, so your monthly cost doubles. Your prescription says how many you take.
Is Rytary the same as Sinemet or Crexont?
No. All three contain carbidopa and levodopa, but they release the medicine differently. Rytary's label says its doses are not interchangeable with other carbidopa-levodopa products, so a pharmacist can't swap one for another without your prescriber.
Sources
- Texas DSHS: 2026 annual WAC report (Amneal Rytary 100 capsules: $415.48 (NDC 64896-661-01, -662-01, -663-01), $522.08 (NDC 64896-664-01); Zydus authorized generic 100 capsules: $358.98 (three lower strengths), $451.08 (61.25 mg/245 mg))
- RYTARY U.S. prescribing information (DailyMed) (Amneal Pharmaceuticals LLC, label version 26 (published March 27, 2026))
- Drugs@FDA: Rytary (NDA 203312) (four strengths, prescription, TE code AB)
- FDA NDC Directory: Zydus carbidopa and levodopa ER capsules (NDC 70710-2140) (NDA authorized generic under NDA 203312, marketing start October 20, 2025)
- Drugs@FDA data: Actavis carbidopa and levodopa ER capsules (ANDA 208522) (approved November 2, 2026, TE code AB)
- Amneal: Rytary Co-Pay Savings Card flyer (terms as printed (flyer dated 07/2020 on Amneal's Rytary site for health professionals); read 2026-11-11)
- FDA Orange Book: carbidopa and levodopa products
- Health Canada Drug Product Database (no product named Rytary; checked 2026-11-11)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.