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Kuvan Price, Generic and Savings
- Lowest price per tablet at U.S. online pharmacies
- Not available
- Lowest price per tablet at online pharmacies abroad
- $47.33 per tabletIn a pack of 30 tablets for $1,420 (before shipping) · brand Kuvan 100 mg, not FDA-approved · ships from New Zealand
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Quick answerAs of Nov 12, 2026, brand Kuvan 100 mg costs from $47.33 per tablet at online pharmacies abroad we compared, before shipping. In the U.S., brand Kuvan tablets list at $5,040.00 for 120, about $42.00 each; generic tablets list from $2,268.00 for 120.
Name check: This page prices Kuvan 100 mg tablets. Kuvan powder packets (100 mg and 500 mg) are a different form and aren't priced here.
Compare Kuvan prices from licensed online pharmacies
| Pharmacy | Medication | Pack | Price per unit | Pack price | Shipping & delivery | Total with shipping | Buy |
|---|---|---|---|---|---|---|---|
| Lowest price per unitOnline pharmacy A | Kuvan (Turkey pack, ships from Mauritius)100 mg · brand · Filled in MauritiusProduct of Turkey | 90 tablets2 other pack sizes
| $6.29 per tablet | $565.68 | Fee not publishedDelivery time not stated | $565.68+ shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy B | Kuvan (Turkey pack, ships from Mauritius)100 mg · brand · Filled in MauritiusProduct of Turkey | 90 tablets2 other pack sizes
| $6.41 per tablet | $576.99 | Fee not publishedDelivery time not stated | $576.99+ shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy C | Kuvan100 mg · brand · Filled in New ZealandMaker listed by pharmacy: Biomarin | 30 tablets | $47.33 per tablet | $1,420 | $9.95Pharmacy's estimate: 4–6 weeks | $1,429.95Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy D | KUVAN 100MG SOLUBLE TABLET 30 (BRAND FROM NEW ZEALAND)100 mg · brand · Filled in New ZealandProduct of New Zealand | 30 tablets | $51.67 per tablet | $1,550 | $14.95Pharmacy's estimate: 4–6 weeks | $1,564.95Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy E | KUVAN100 mg · brand · Filled in NEW ZEALANDMade for sale in NEW ZEALAND.Product of New Zealand | 30 tablets | $57.05 per tablet | $1,711.43 | FreeDelivery time not stated | $1,711.43Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy F | KUVAN100 mg · brand · Filled in NEW ZEALANDMade for sale in NEW ZEALAND.Product of New Zealand | 30 tablets | $57.13 per tablet | $1,713.82 | FreeDelivery time not stated | $1,713.82Checked Nov 12 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Kuvan from Canada?
Each row is one product from one pharmacy, shown in the pack size with the lowest price per unit; its other pack sizes are listed under “other pack sizes”. Price per unit = the pack price divided by the units in the pack, before shipping; we sort by it and don't assume how long a pack lasts. Total with shipping = the pack price plus the pharmacy's shipping fee for one order. Prices checked Nov 12, 2026 on each pharmacy's website, in U.S. dollars (converted when a pharmacy prices in Canadian dollars). The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Prices change often; confirm at checkout. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
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Prices per tablet from 4 licensed pharmacies shipping to the U.S.: $47.33 to $57.13, any strength, before shipping.
Jump to: U.S. cost · Medicare · Maker savings · Generic Kuvan · Uses · FAQ
Kuvan (sapropterin) 100 mg tablets, dissolved in water or juice, for a type of PKU. FDA-approved generics are sold in the U.S.
Kuvan cost at a glance
- U.S. list price: $5,040.00 for a bottle of 120 brand Kuvan 100 mg tablets, about $42.00 a tablet. That's BioMarin's wholesale price before discounts (Texas DSHS).
- Generic Kuvan is sold in the U.S., for less. Several companies sell FDA-approved generic sapropterin 100 mg tablets, rated equivalent to Kuvan (FDA Orange Book). In the 2026 filing, Hikma lists 120 tablets at $2,268.00; Aurobindo, Annora, Northstar and Par list $3,240.00 (Texas DSHS).
- How we compare: per tablet. The dose is set by body weight (5 to 20 mg per kg once a day), so we list each pharmacy's packs as sold and compare the price per tablet.
- From online pharmacies abroad: $47.33 to $57.13 per tablet of brand Kuvan 100 mg, before shipping (checked Nov 12, 2026). Packs made for other countries are not FDA-approved.
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
How much does Kuvan cost in the U.S.?
| If you have | What Kuvan costs | Source |
|---|---|---|
| No insurance (brand list price) | $5,040.00 for 120 tablets of Kuvan 100 mg. Pharmacies may charge more. | Texas DSHS 2026 WAC report |
| No insurance (generic) | Generic sapropterin 100 mg tablets list from $2,268.00 for 120 (Hikma); others list $3,240.00. Ask your pharmacist for the cash price. | Texas DSHS 2026 WAC report |
| Private or employer insurance | Your copay depends on your plan's drug list. Ask your plan or pharmacist what you'd pay for brand Kuvan and for generic sapropterin dihydrochloride. | FDA Orange Book |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Brand Kuvan tablets list at $5,040.00 for a bottle of 120 in the U.S. (Texas DSHS). The same filing lists FDA-approved generic sapropterin tablets from $2,268.00 for 120. These are list prices; what a pharmacy charges can differ.
Kuvan cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Kuvan or generic sapropterin dihydrochloride depends on your plan's drug list.
| Medicare Part D | What Kuvan costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Savings programs from the maker
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
Checking more than one medicine? Use the free Medicare Drug Cost Check.
eDrugSearch does not offer its own Kuvan coupons. eDrugSearch has no coupons of its own. If you have Medicare, these two programs can help with the cost of Kuvan:
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Kuvan?
Yes. The FDA has approved generic sapropterin 100 mg tablets from several makers, rated equivalent to Kuvan. The first was approved on May 10, 2019.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 100 mg | Yes | PH Health (Par), Dr. Reddy's, Annora, Aurobindo, Hikma | May 10, 2019 |
Outside the U.S.: Online pharmacies abroad may sell generic sapropterin made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: Drugs@FDA: sapropterin generics. As of Nov 14, 2026.
What is Kuvan used for?
Kuvan (sapropterin dihydrochloride) is a form of BH4, a natural helper molecule that some people with PKU respond to. According to its FDA label (DailyMed), it is used:
- To lower blood phenylalanine (Phe) levels in adults and children 1 month and older who have PKU that responds to BH4. It is used together with a Phe-restricted diet.
The label says the tablets are dissolved in water or apple juice and taken once a day with a meal. The dose depends on body weight (10 to 20 mg per kg to start, adjusted between 5 and 20 mg per kg), and blood Phe is checked regularly. Your prescriber decides which medicine is right for you.
Is it safe to order Kuvan from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Kuvan, compare the U.S. price of FDA-approved generic tablets before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, Kuvan 100 mg tablets from BioMarin are listed as marketed (Health Canada Drug Product Database, checked 2026-11-14).
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much is Kuvan without insurance?
Brand Kuvan tablets list at $5,040.00 for 120 in the U.S., about $42.00 each; generic tablets list from $2,268.00 for 120. Online pharmacies abroad charged from $47.33 per tablet for brand Kuvan in our latest check (Nov 12, 2026), before shipping.
Is there a generic Kuvan?
Yes. Generic sapropterin 100 mg tablets have been FDA-approved since 2019, from several makers. Ask your pharmacist whether a generic can fill your prescription.
How many Kuvan tablets do people take?
It depends on body weight. The label's dose is 5 to 20 mg per kg once a day, so the number of 100 mg tablets differs from person to person.
How much does Kuvan cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help.
Can I buy Kuvan from Canada?
Kuvan 100 mg tablets are sold in Canada by BioMarin. Federal law generally doesn't allow individuals to import prescription drugs, though the FDA has long used enforcement discretion for some personal-use shipments of up to a three-month supply. You need a prescription.
Sources
- Kuvan U.S. prescribing information (DailyMed) (BioMarin label, version 79, effective 2024-08-26: BH4-responsive PKU with Phe-restricted diet; 5 to 20 mg/kg once daily; tablets dissolved; bottles of 120)
- Drugs@FDA: Kuvan tablets (NDA 022181) (approved December 13, 2007; 100 mg Prescription AB)
- Drugs@FDA: sapropterin generics (tablets: PH Health 2019-05-10; Dr. Reddy's 2021-06-15; Annora 2022-08-23; Aurobindo 2025-06-09; Hikma 2025-06-11)
- FDA Orange Book: sapropterin tablets
- FDA NDC Directory: Kuvan (68135-300-02 (120 tablets), BioMarin, active; checked 2026-11-14)
- Texas DSHS 2026 WAC report: Kuvan and generics (BioMarin KUVAN 68135030002 (120 tablets) Trade $5,040.00; Hikma 00054090623 (120) $2,268.00; Aurobindo, Annora, Northstar, Par (120) $3,240.00)
- Health Canada Drug Product Database: Kuvan (DIN 02350580 (100 mg tablet), BioMarin International, Marketed)
- Texas DSHS: 2026 annual WAC report
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.