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Daliresp Cost, Coupons and Savings
- U.S. list price
- $1,412.55 for 90 days (90 tablets)The maker's price for brand Daliresp before discounts · Source: Texas DSHS 2026 WAC report
- Lowest international online pharmacy price
- $2.75 per tablet$262.20 for 90 days (90 tablets), shipping included · brand Daliresp 500 mcg, not FDA-approved · ships from United Kingdom
FDA-approved generic roflumilast 500 mcg from $71.60 for 90 days at U.S. pharmacies
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Quick answerAs of Nov 11, 2026, brand Daliresp 500 mcg costs from $261.95 for 90 days at licensed pharmacies abroad we compared, vs. $1,412.56 at the U.S. list price (90 tablets). FDA-approved generic roflumilast is sold in the U.S.
Name check: In Canada, AstraZeneca sells roflumilast 500 mcg tablets as Daxas. Zoryve, a roflumilast product for the skin, is a separate medicine and isn't priced here.
Compare Daliresp prices from licensed online pharmacies
For comparison U.S. pharmacy list price: $1,412.55 for 90 days ($15.70 per tablet), brand Daliresp 500 mcg before insurance. The prices below are from U.S. pharmacies that publish cash prices and from licensed online pharmacies outside the U.S.
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per tabletLicensed U.S. pharmacy A | Roflumilast (Daliresp) 500 mcg500 mcg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $66.60for 90 tablets$0.74 per tablet | $5Pharmacy's estimate: 2–8 business days | $71.60 for 90 days= $71.60 for 90 daysSave 95%incl. $5 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy B | Roflumilast 500mcg Tablet500 mcg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $100.10for 90 tablets$1.11 per tablet | FreePharmacy's estimate: 3–5 business days | $100.10 for 90 days= $100.10 for 90 daysSave 93%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | DAXAS (Canadian name for Daliresp) (sold in the U.K. as Daxas)250 mcg · brand · Filled in UKProduct of UK | $193.71for 84 tablets$2.31 per tablet | FreeDelivery time not stated | $193.71 for 84 days= $207.55 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy D | Daxas (Canadian name for Daliresp)500 mcg · brand · Filled in CanadaProduct of Canada | $248.45for 90 tablets$2.76 per tablet | Fee not publishedDelivery time not stated | $248.45 for 90 days= $248.45 for 90 days+ shippingSave 82%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | Brand Daxas 250mcg (Canadian name for Daliresp)250 mcg · brand · Filled in United KingdomProduct of United Kingdom | $239.04for 90 tablets$2.66 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $253.99 for 90 days= $253.99 for 90 daysincl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy F | Daxas (Canadian name for Daliresp)500 mcg · brand · Filled in CanadaProduct of Canada | $258.99for 90 tablets$2.88 per tablet | Fee not publishedDelivery time not stated | $258.99 for 90 days= $258.99 for 90 days+ shippingSave 82%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy G | Daxas (Canadian name for Daliresp)500 mcg · brand · Filled in United KingdomMaker listed by pharmacy: AstraZeneca | $252for 90 tablets$2.80 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $261.95 for 90 days= $261.95 for 90 daysSave 81%incl. $9.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | Brand Daxas 500mcg (Canadian name for Daliresp)500 mcg · brand · Filled in United KingdomProduct of United Kingdom | $247.25for 90 tablets$2.75 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $262.20 for 90 days= $262.20 for 90 daysSave 81%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy H | Brand Daxas 250mcg (Canadian name for Daliresp)250 mcg · brand · Filled in United KingdomProduct of United Kingdom | $247.89for 90 tablets$2.75 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $262.84 for 90 days= $262.84 for 90 daysincl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy H | Brand Daxas 500mcg (Canadian name for Daliresp)500 mcg · brand · Filled in United KingdomProduct of United Kingdom | $256.41for 90 tablets$2.85 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $271.36 for 90 days= $271.36 for 90 daysSave 81%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy G | Daxas (Canadian name for Daliresp)250 mcg · brand · Filled in United KingdomMaker listed by pharmacy: AstraZeneca | $246for 84 tablets$2.93 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $255.95 for 84 days= $274.23 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy G | Daxas (Canadian name for Daliresp)500 mcg · brand · Filled in CanadaMaker listed by pharmacy: AstraZeneca | $270for 90 tablets$3.00 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $279.95 for 90 days= $279.95 for 90 daysSave 80%incl. $9.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed Canadian pharmacy I | Daliresp 500mcg500 mcg · brand · Filled in CanadaProduct of Canada | $328for 90 tablets$3.64 per tablet | FreeDelivery time not stated | $328 for 90 days= $328 for 90 daysSave 77%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy J | Daxas (Roflumilast) (Canadian name for Daliresp)500 mcg · brand · Filled in CanadaMaker listed by pharmacy: Takeda Pharmaceutical Co. | $332.70for 90 tablets$3.70 per tablet | FreePharmacy's estimate: 2–3 weeks | $332.70 for 90 days= $332.70 for 90 daysSave 76%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed Canadian pharmacy K | Daxas (Canadian name for Daliresp)500 mcg · brand · Filled in CanadaMaker listed by pharmacy: Astra-Zeneca Canada Inc. | $324.58for 90 tablets$3.61 per tablet | $9.95Pharmacy's estimate: 3–6 weeks | $334.53 for 90 days= $334.53 for 90 daysSave 76%incl. $9.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | DAXAS (Canadian name for Daliresp) (sold in the U.K. as Daxas)500 mcg · brand · Filled in UKProduct of UK | $107.23per 28 tablets · 3 packs = $321.69$3.83 per tablet | FreeDelivery time not stated | $321.69 for 84 days= $344.67 for 90 daysSave 76%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | DALIRESP (sold in the U.K. as Daxas)500 mcg · brand · Filled in UKProduct of UK | $358.63for 90 tablets$3.98 per tablet | FreeDelivery time not stated | $358.63 for 90 days= $358.63 for 90 daysSave 75%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy L | DALIRESP (sold in the U.K. as Daxas)500 mcg · brand · Filled in United KingdomProduct of United Kingdom | $361.02for 90 tablets$4.01 per tablet | FreeDelivery time not stated | $361.02 for 90 days= $361.02 for 90 daysSave 74%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | DALIRESP (sold in the U.K. as Daxas)250 mcg · brand · Filled in UKProduct of UK | $337.31for 84 tablets$4.02 per tablet | FreeDelivery time not stated | $337.31 for 84 days= $361.40 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy L | DALIRESP (sold in the U.K. as Daxas)250 mcg · brand · Filled in United KingdomProduct of United Kingdom | $339.70for 84 tablets$4.04 per tablet | FreeDelivery time not stated | $339.70 for 84 days= $363.96 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy M | Daxas (UK/EU pack, ships from United Kingdom) (Canadian name for Daliresp)250 mcg · brand · Filled in United KingdomProduct of UK/EU | $345.33for 84 tablets$4.11 per tablet | $9.95Delivery time not stated | $355.28 for 84 days= $380.66 for 90 daysWorked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy M | Daxas (Canadian name for Daliresp)500 mcg · brand · Filled in CanadaProduct of Canada | $427.62for 90 tablets$4.75 per tablet | $9.95Delivery time not stated | $437.57 for 90 days= $437.57 for 90 daysSave 69%incl. $9.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy L | DALIRESP500 mcg · brand · Filled in CanadaProduct of Canada | $439.09for 90 tablets$4.88 per tablet | FreeDelivery time not stated | $439.09 for 90 days= $439.09 for 90 daysSave 69%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy B | Roflumilast 250mcg Tablet250 mcg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $1,053.95for 90 tablets$11.71 per tablet | FreePharmacy's estimate: 3–5 business days | $1,053.95 for 90 days= $1,053.95 for 90 daysincl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy NU.S. shipping limited | Daliresp (Roflumilast) - Also Known as Daxas (Canadian name for Daliresp)500 mcg · brand · Filled in United KingdomProduct of United Kingdom | $338for 90 tablets$3.76 per tablet | $14.95Pharmacy's estimate: 8–14 business days | $352.95 for 90 days= $352.95 for 90 daysSave 75%incl. $14.95 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy D | Roflumilast (India pack, ships from Mauritius)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.500 mcg · generic · Filled in MauritiusProduct of India | $71.09for 100 tablets$0.71 per tabletOver 3-month supply | Fee not publishedDelivery time not stated | $71.09 for 100 days= $63.98 for 90 days+ shippingSave 95%Worked out from a 100-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy F | Roflumilast (India pack, ships from Mauritius)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.500 mcg · generic · Filled in MauritiusProduct of India | $81.99for 100 tablets$0.82 per tabletOver 3-month supply | Fee not publishedDelivery time not stated | $81.99 for 100 days= $73.79 for 90 days+ shippingSave 95%Worked out from a 100-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy J | Roflumilast (Roflumilast) (India pack, ships from Turkey)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.500 mcg · generic · Filled in TurkeyMaker listed by pharmacy: LupinMade for India | $131.79for 100 tablets$1.32 per tabletOver 3-month supply | FreePharmacy's estimate: 2–3 weeks | $131.79 for 100 days= $118.61 for 90 daysSave 92%Worked out from a 100-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy M | Roflumilast (India pack, ships from Mauritius)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.500 mcg · generic · Filled in MauritiusProduct of India | $125.03for 100 tablets$1.25 per tabletOver 3-month supply | $9.95Delivery time not stated | $134.98 for 100 days= $121.48 for 90 daysSave 91%Worked out from a 100-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy NU.S. shipping limited | Roflumilast (Generic)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.500 mcg · generic · Filled in IndiaMade for sale in India.Product of India | $154for 100 tablets$1.54 per tabletOver 3-month supply | $14.95Pharmacy's estimate: 8–14 business days | $168.95 for 100 days= $152.06 for 90 daysSave 89%Worked out from a 100-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Daliresp from Canada?
90-day cost = 90 tablets at the usual dose of 1 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price of the same strength (500 mcg); rows for other strengths show no saving. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
Members see pharmacy names, ratings, visit links and price-drop alerts.
Join to See PharmaciesAlready a member? Sign inDaliresp price by strength
| Strength | Lowest brand90 days | Price per tablet |
|---|---|---|
| Daliresp 250 mcg | $207.55 | $2.31 |
| Daliresp 500 mcg | $261.95 | $2.80 |
Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per tablet is for that lowest pack, before shipping. Prices checked Nov 11, 2026.
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90-day prices from 9 licensed pharmacies abroad shipping to the U.S.: $207.55 to $439.09, any strength, shipping included.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Daliresp · Similar drugs · Uses · FAQ
Daliresp (roflumilast) 250 and 500 mcg tablets, taken once a day to cut the risk of COPD flare-ups. FDA-approved generic roflumilast is sold in the U.S.
Daliresp cost at a glance
- Generic Daliresp is sold in the U.S. The FDA has approved generic roflumilast tablets (250 and 500 mcg) from many companies, rated equivalent to Daliresp (FDA Orange Book). The U.S. list price of Zydus's generic 500 mcg is $18.24 for 30 tablets and $54.65 for 90 (Texas DSHS).
- U.S. list price: $470.85 for 30 tablets or $1,412.56 for 90 tablets of brand Daliresp 500 mcg (the maker's wholesale price before discounts). The 250 mcg starter pack of 28 tablets lists at $439.45 (Texas DSHS).
- Savings card: AstraZeneca says eligible patients with commercial insurance may pay as little as $25 for Daliresp. Terms apply, and people in federal government insurance programs are excluded.
- How we count: 1 tablet a day. The label's maintenance dose is one 500 mcg tablet a day; 250 mcg is a starting dose for the first 4 weeks only.
- From online pharmacies abroad: $261.95 to $439.09 for 90 days of brand Daliresp 500 mcg, shipping included (checked Nov 11, 2026). The U.S. list price for 90 tablets is $1,412.56.
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
How much does Daliresp cost in the U.S.?
| If you have | What Daliresp costs | Source |
|---|---|---|
| No insurance (list price) | $1,412.56 for 90 tablets of brand Daliresp 500 mcg ($470.85 for 30). The 250 mcg pack of 28 tablets is $439.45. Pharmacies may charge more. | Texas DSHS 2026 WAC report |
| No insurance (generic roflumilast) | FDA-approved generic roflumilast is sold in the U.S. Zydus's generic 500 mcg lists at $18.24 for 30 tablets and $54.65 for 90. Ask your pharmacist for the cash price. | Texas DSHS 2026 WAC report |
| Private or employer insurance | Your copay depends on your plan's drug list. With commercial insurance, AstraZeneca says eligible patients may pay as little as $25 for brand Daliresp (terms apply). | AstraZeneca |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. AstraZeneca's copay savings can't be used. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Brand Daliresp 500 mcg has a U.S. list price of $470.85 for 30 tablets and $1,412.56 for 90 (Texas DSHS). This is the maker's wholesale price before discounts. FDA-approved generic roflumilast is sold in the U.S., and its list prices in the same report are far lower: $54.65 for 90 tablets from Zydus and $125.50 for 90 from Solco.
Daliresp cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for brand Daliresp or generic roflumilast depends on your plan's drug list. AstraZeneca's copay savings can't be used with Medicare.
| Medicare Part D | What Daliresp costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Daliresp coupons and savings programs
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
Checking more than one medicine? Use the free Medicare Drug Cost Check.
eDrugSearch does not offer its own Daliresp coupons. These are the programs we could verify for brand Daliresp:
- Daliresp savings offer (AstraZeneca): AstraZeneca says eligible patients with commercial insurance may pay as little as $25 for brand Daliresp. Terms and conditions apply. People enrolled in federal government insurance programs, such as Medicare and Medicaid, can't use copay support. (azpatientsupport.com)
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Daliresp?
Yes. The FDA has approved generic roflumilast tablets (250 and 500 mcg) from many companies, including Zydus, Hetero, Micro Labs, Strides, Prinston (Solco), MSN, Aurobindo, Alkem and others, all rated equivalent to Daliresp. The first approvals came in 2018. FDA drug listings show generic roflumilast on the U.S. market today, for example from Zydus (listed since October 3, 2022).
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 250 mcg | Yes | Zydus, Hetero, Micro Labs, Strides, Prinston (Solco), MSN, Aurobindo, Alkem and others | — |
| 500 mcg | Yes | Zydus, Hetero, Micro Labs, Strides, Prinston (Solco), MSN, Aurobindo, Alkem and others | — |
Outside the U.S.: Online pharmacies abroad may also sell generic roflumilast made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: FDA Orange Book: roflumilast products. As of Nov 11, 2026.
Compare Daliresp with similar drugs
Other COPD medicines people often look up alongside Daliresp. These are inhalers and work in different ways. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Breztri Aerospherebudesonide, glycopyrrolate and formoterol fumarate | COPD and asthma inhaler (a steroid plus two long-acting bronchodilators) | $457.17 for 90 days | See prices |
| Trelegy Elliptafluticasone furoate, umeclidinium and vilanterol | COPD and asthma inhaler (a steroid plus two long-acting bronchodilators) | $187.71 for 90 days | See prices |
| Anoro Elliptaumeclidinium and vilanterol | COPD inhaler (two long-acting bronchodilators: an anticholinergic plus a LABA) | $129.95 for 90 days | See prices |
| Spiriva Respimattiotropium bromide | COPD and asthma maintenance inhaler (long-acting anticholinergic bronchodilator) | $208.99 for 90 days | See prices |
| Spiriva HandiHalertiotropium bromide | COPD maintenance inhaler (long-acting anticholinergic bronchodilator) | $64.59 for 90 days | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Daliresp used for?
Daliresp (roflumilast) is a phosphodiesterase-4 (PDE4) inhibitor, a once-a-day tablet for COPD. According to its FDA label (DailyMed), it is used:
- To lower the risk of COPD flare-ups (exacerbations) in people with severe COPD linked to chronic bronchitis who have a history of flare-ups.
Daliresp is not a bronchodilator, and the label says it is not for relief of sudden breathing problems. It comes as 250 mcg and 500 mcg tablets taken once a day, with or without food. The label says 250 mcg is only a starting dose for the first 4 weeks; the regular dose is 500 mcg. Daliresp has no boxed warning. It must not be used by people with moderate or severe liver problems, and the label warns about mood changes, including thoughts of suicide. Your prescriber decides which medicine is right for you.
Is it safe to order Daliresp from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Daliresp, compare the U.S. price of FDA-approved generic roflumilast before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, AstraZeneca sells roflumilast 500 mcg tablets as Daxas (Health Canada).
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much is Daliresp without insurance?
The U.S. list price of brand Daliresp 500 mcg is $470.85 for 30 tablets, or $1,412.56 for 90 (the maker's wholesale price before discounts). Licensed pharmacies abroad charged from $261.95 for 90 days of brand Daliresp 500 mcg in our latest check (Nov 11, 2026). FDA-approved generic roflumilast is also sold in the U.S.; ask your pharmacist for its cash price.
Is there a generic Daliresp?
Yes. The FDA has approved generic roflumilast tablets (250 and 500 mcg) from many companies, rated equivalent to Daliresp. The first approvals came in 2018. The generic name is roflumilast. Ask your pharmacist whether a generic can fill your prescription.
How much does generic roflumilast cost?
At list prices, 90 tablets of generic roflumilast 500 mcg cost $54.65 from Zydus and $125.50 from Solco, compared with $1,412.56 for brand Daliresp. These are list prices; ask your pharmacist what you would pay.
Is there a Daliresp coupon or savings card?
Yes, for people with commercial insurance. AstraZeneca says eligible patients may pay as little as $25 for Daliresp, and terms apply. People in federal government insurance programs, such as Medicare and Medicaid, can't use it. eDrugSearch doesn't offer coupons of its own.
How much does Daliresp cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. AstraZeneca's copay savings can't be used with Medicare. People with limited income can apply for Extra Help.
Is Daxas the same as Daliresp?
Daxas is the name AstraZeneca uses for roflumilast 500 mcg tablets in Canada. It has the same active ingredient as Daliresp, but it's made for sale in other countries and isn't FDA-approved. The price table shows the name, maker and country of each pack.
What strengths does Daliresp come in?
Daliresp comes in 250 mcg and 500 mcg tablets. The label says 250 mcg is a starting dose for the first 4 weeks only, and the regular dose is one 500 mcg tablet a day.
Sources
- Texas DSHS: 2026 annual WAC report (Daliresp list prices by NDC (0310-0095-30, 0310-0095-90, 0310-0088-28, 0310-0088-39); generic roflumilast list prices (Zydus, Solco, Micro Labs))
- DALIRESP U.S. prescribing information (DailyMed) (AstraZeneca Pharmaceuticals LP, label version 15, effective March 12, 2020)
- Drugs@FDA: Daliresp (NDA 022522) (both strengths Prescription, TE code AB)
- FDA Orange Book: roflumilast products
- Drugs@FDA: generic roflumilast (ANDA 208213, Hetero) (approved November 23, 2018)
- FDA NDC Directory: Zydus roflumilast 500 mcg (NDC 68382-969) (marketing start October 3, 2022)
- AstraZeneca patient support: Daliresp savings (checked 2026-11-11)
- Health Canada Drug Product Database: Daxas 500 mcg (AstraZeneca Canada, DIN 02359456, Marketed)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.