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Ampyra Cost, Coupons and Generic
- U.S. list price
- $13,409.28 for 90 days (180 tablets)The maker's price for brand Ampyra before discounts · Source: Texas DSHS 2026 WAC report
- Lowest international online pharmacy price
- $4.77 per tablet$858.99 for 90 days (180 tablets), shipping included · brand Ampyra 10 mg, not FDA-approved · ships from New Zealand
FDA-approved generic dalfampridine 10 mg from $170.60 for 90 days at U.S. pharmacies
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Quick answerAs of Nov 11, 2026, brand Ampyra 10 mg costs from $858.99 for 90 days at licensed pharmacies abroad we compared, vs. $13,409.28 at the U.S. list price ($4,469.76 for 60 tablets). FDA-approved generic dalfampridine is sold in the U.S., with list prices from $16.00 for 60 tablets.
Name check: Outside the U.S., this medicine is sold as Fampyra (fampridine is another name for dalfampridine). The price table labels those packs with the name they're sold under.
Compare Ampyra prices from licensed online pharmacies
For comparison U.S. pharmacy list price: $13,409.28 for 90 days ($74.50 per tablet), brand Ampyra before insurance. The prices below are from U.S. pharmacies that publish cash prices and from licensed online pharmacies outside the U.S.
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per tabletLicensed U.S. pharmacy A | Dalfampridine 10mg ER Tablets10 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $165.60for 180 tablets$0.92 per tablet | $5Pharmacy's estimate: 2–8 business days | $170.60 for 90 days= $170.60 for 90 daysSave 99%incl. $5 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy B | Dalfampridine ER 10mg Tablet10 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026 | $105.59per 90 tablets · 2 packs = $211.18$1.17 per tablet | FreePharmacy's estimate: 3–5 business days | $211.18 for 90 days= $211.18 for 90 daysSave 98%incl. $0 shippingChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | AMPYRA (EU pack, ships from New Zealand)10 mg · brand · Filled in New ZealandProduct of EU | $801.72for 168 tablets$4.77 per tablet | FreeDelivery time not stated | $801.72 for 84 days= $858.99 for 90 daysSave 94%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy D | AMPYRA10 mg · brand · Filled in New ZealandProduct of New Zealand | $804.11for 168 tablets$4.79 per tablet | FreeDelivery time not stated | $804.11 for 84 days= $861.55 for 90 daysSave 94%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | Fampyra (sold outside the U.S. as Fampyra)10 mg · brand · Filled in AustraliaProduct of Australia | $313.85per 56 tablets · 3 packs = $941.55$5.60 per tablet | Fee not publishedDelivery time not stated | $941.55 for 84 days= $1,008.80 for 90 days+ shippingSave 92%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy F | Fampyra (sold outside the U.S. as Fampyra)10 mg · brand · Filled in AustraliaProduct of Australia | $324.99per 56 tablets · 3 packs = $974.97$5.80 per tablet | Fee not publishedDelivery time not stated | $974.97 for 84 days= $1,044.61 for 90 days+ shippingSave 92%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy G | AMPYRA 10MG TABLET 112 (FAMPYRA BRAND FROM NEW ZEALAND) (sold outside the U.S. as Fampyra)10 mg · brand · Filled in New ZealandProduct of New Zealand | $645for 112 tablets$5.76 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $659.95 for 56 days= $1,060.63 for 90 daysSave 92%Worked out from a 56-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy G | AMPYRA 10MG TABLET 56 (FAMPYRA BRAND FROM NEW ZEALAND) (sold outside the U.S. as Fampyra)10 mg · brand · Filled in New ZealandProduct of New Zealand | $335per 56 tablets · 3 packs = $1,005$5.98 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $1,019.95 for 84 days= $1,092.80 for 90 daysSave 92%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy H | Fampyra (sold outside the U.S. as Fampyra)10 mg · brand · Filled in New ZealandMaker listed by pharmacy: Biogen | $1,355.70for 168 tablets$8.07 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $1,370.65 for 84 days= $1,468.55 for 90 daysSave 89%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy I | Fampyra (sold outside the U.S. as Fampyra)10 mg · brand · Filled in AustraliaProduct of Australia | $461.79per 56 tablets · 3 packs = $1,385.37$8.25 per tablet | $9.95Delivery time not stated | $1,395.32 for 84 days= $1,494.99 for 90 daysSave 89%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy J | Fampyra (Fampridine) (sold outside the U.S. as Fampyra)10 mg · brand · Filled in New ZealandMaker listed by pharmacy: Biogen Idec | $1,415.94for 168 tablets$8.43 per tablet | FreePharmacy's estimate: 2–3 weeks | $1,415.94 for 84 days= $1,517.08 for 90 daysSave 89%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy K | Brand Fampyra 10mg (sold outside the U.S. as Fampyra)10 mg · brand · Filled in CanadaMaker listed by pharmacy: Biogen Idec Canada Inc | $1,834.04for 168 tablets$10.92 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $1,848.99 for 84 days= $1,981.06 for 90 daysSave 85%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy L | Ampyra10 mg · brand · Filled in New ZealandMaker listed by pharmacy: Biogen Idec | $1,947for 168 tablets$11.59 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $1,956.95 for 84 days= $2,096.73 for 90 daysSave 84%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy M | Brand Fampyra 10mg (sold outside the U.S. as Fampyra)10 mg · brand · Filled in CanadaMaker listed by pharmacy: Biogen Idec Canada Inc | $2,010.65for 168 tablets$11.97 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $2,025.60 for 84 days= $2,170.29 for 90 daysSave 84%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy L | Ampyra10 mg · brand · Filled in CanadaMaker listed by pharmacy: Biogen Idec | $685per 56 tablets · 3 packs = $2,055$12.23 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $2,064.95 for 84 days= $2,212.45 for 90 daysSave 84%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed Canadian pharmacy N | Fampyra (sold outside the U.S. as Fampyra)10 mg · brand · Filled in CanadaMaker listed by pharmacy: MERZ THERAPEUTICS GMBH | $2,095.82for 168 tablets$12.48 per tablet | $9.95Pharmacy's estimate: 3–6 weeks | $2,105.77 for 84 days= $2,256.18 for 90 daysSave 83%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy J | Fampyra (Fampridine) (sold outside the U.S. as Fampyra)10 mg · brand · Filled in CanadaMaker listed by pharmacy: Biogen Idec | $3,036.80for 168 tablets$18.08 per tablet | FreePharmacy's estimate: 2–3 weeks | $3,036.80 for 84 days= $3,253.71 for 90 daysSave 76%Worked out from an 84-day orderChecked Nov 11 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Ampyra from Canada?
90-day cost = 180 tablets at the usual dose of 2 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
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Join to See PharmaciesAlready a member? Sign inAmpyra price by strength
| Strength | Lowest brand90 days | Price per tablet |
|---|---|---|
| Ampyra 10 mg | $858.99 | $4.77 |
Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per tablet is for that lowest pack, before shipping. Prices checked Nov 11, 2026.
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90-day prices from 10 licensed pharmacies abroad shipping to the U.S.: $858.99 to $3,253.71, any strength, shipping included.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Ampyra · Similar drugs · Uses · FAQ
Ampyra (dalfampridine) 10 mg extended-release tablets help improve walking in adults with MS. FDA-approved generic dalfampridine is sold in the U.S.
Ampyra cost at a glance
- Generic Ampyra is sold in the U.S. The FDA has approved generic dalfampridine extended-release 10 mg tablets from several companies, rated equivalent to Ampyra (FDA Orange Book). U.S. list prices for 60 generic tablets include $16.00 (CivicaScript) and $60.00 (Aurobindo, Actavis, Micro Labs) (Texas DSHS).
- U.S. list price: $4,469.76 for a bottle of 60 tablets of brand Ampyra 10 mg, a 30-day supply (the maker's wholesale price before discounts). That's about $74.50 a tablet (Texas DSHS).
- How we count: 2 tablets a day. The label's dose is one 10 mg tablet twice a day, about 12 hours apart, so 90 days is 180 tablets.
- From online pharmacies abroad: $858.99 to $3,253.71 for 90 days (180 tablets) of brand Ampyra 10 mg, shipping included (checked Nov 11, 2026). The U.S. list price for 180 tablets is $13,409.28.
- Savings: with commercial insurance, Merz's co-pay program may lower your cost to as little as $0. It isn't for Medicare, Medicaid or other government plans (Ampyra.com).
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
How much does Ampyra cost in the U.S.?
| If you have | What Ampyra costs | Source |
|---|---|---|
| No insurance (list price) | $4,469.76 for 60 tablets of brand Ampyra 10 mg (30 days), about $74.50 a tablet. Pharmacies may charge more. | Texas DSHS 2026 WAC report |
| No insurance (generic dalfampridine) | FDA-approved generic dalfampridine is sold in the U.S. List prices for 60 tablets (30 days) include $16.00 (CivicaScript) and $60.00 (Aurobindo, Actavis, Micro Labs). Ask your pharmacist for the cash price. | Texas DSHS 2026 WAC report |
| Private or employer insurance | Your copay depends on your plan's drug list. Merz's co-pay program may lower your cost for brand Ampyra to as little as $0. | Ampyra.com |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Brand Ampyra 10 mg lists at $4,469.76 for 60 tablets, a 30-day supply (Texas DSHS). This is the maker's wholesale price before discounts. FDA-approved generic dalfampridine has been sold in the U.S. since 2018, and the same filing lists 60 generic tablets at $16.00 from CivicaScript and $60.00 from several other makers. What a pharmacy charges you can differ.
Ampyra cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for brand Ampyra or generic dalfampridine depends on your plan's drug list.
| Medicare Part D | What Ampyra costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Ampyra coupons and savings programs
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
Checking more than one medicine? Use the free Medicare Drug Cost Check.
eDrugSearch does not offer its own Ampyra coupons. These programs can help with the cost of brand Ampyra or generic dalfampridine:
- Ampyra co-pay program (MyAmpyra): for adults with commercial insurance (through work or bought on their own). It may lower your cost for brand Ampyra to as little as $0. Not for Medicare (including Part D and Medicare Advantage), Medicaid, VA, TRICARE or other government-funded programs. Call 1-855-866-9255. (Ampyra.com)
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Ampyra?
Yes. The FDA has approved generic dalfampridine extended-release 10 mg tablets from several companies, including Aurobindo, Actavis, Accord, Alkem and Micro Labs, all rated equivalent to Ampyra. The first were approved January 23, 2017, and Aurobindo's has been listed as on the U.S. market since June 25, 2018.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 10 mg | Yes | Aurobindo, Actavis, Accord, Alkem (CivicaScript), Micro Labs | Jun 25, 2018 |
Outside the U.S.: Online pharmacies abroad may also sell generic fampridine made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: FDA Orange Book: dalfampridine products. As of Nov 11, 2026.
Compare Ampyra with similar drugs
Other multiple sclerosis medicines on eDrugSearch. Gilenya, Tecfidera and Vumerity treat relapsing MS itself, while Ampyra helps with walking, so they aren't substitutes; your prescriber decides which medicine is right for you. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Gilenyafingolimod | Multiple sclerosis medicine (S1P receptor modulator) | $928.30 for 90 days | See prices |
| Tecfideradimethyl fumarate | Multiple sclerosis medicine (fumarate) | $732.26 for 90 days | See prices |
| Vumeritydiroximel fumarate | Multiple sclerosis medicine (fumarate) | Checking prices | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Ampyra used for?
Ampyra (dalfampridine) is a potassium channel blocker. It helps damaged nerves carry signals better. According to its FDA label (DailyMed), it is used:
- To improve walking in adults with multiple sclerosis (MS). In studies, this showed up as faster walking speed.
Ampyra is one 10 mg extended-release tablet taken twice a day, about 12 hours apart, with or without food. The label says to swallow it whole (not split, crushed or chewed) and not to take more than 10 mg twice a day because higher doses raise the risk of seizures. The label also says it must not be used by people who have ever had a seizure or who have moderate or severe kidney problems. Ampyra has no boxed warning. Your prescriber decides which medicine is right for you.
Is it safe to order Ampyra from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Ampyra, compare the U.S. price of FDA-approved generic dalfampridine before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, Merz sells this medicine as Fampyra 10 mg extended-release tablets (Health Canada).
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much is Ampyra without insurance?
The U.S. list price of brand Ampyra 10 mg is $4,469.76 for 60 tablets, a 30-day supply (the maker's wholesale price before discounts). Licensed pharmacies abroad charged from $858.99 for 90 days of brand Ampyra in our latest check (Nov 11, 2026). FDA-approved generic dalfampridine is also sold in the U.S., with list prices from $16.00 for 60 tablets.
Is there a generic Ampyra?
Yes. The FDA has approved generic dalfampridine extended-release 10 mg tablets from several companies, rated equivalent to Ampyra. Generics have been sold in the U.S. since 2018. Ask your pharmacist whether a generic can fill your prescription.
Is Ampyra more expensive than dalfampridine?
At list prices, yes. Sixty tablets of brand Ampyra list at $4,469.76, while 60 tablets of generic dalfampridine list at $16.00 (CivicaScript), $60.00 (Aurobindo, Actavis, Micro Labs) or $120.00 (Accord, Ascend, Sun). These are list prices; ask your pharmacist what you would pay. Your prescriber decides which medicine is right for you.
Is there an Ampyra coupon or co-pay card?
eDrugSearch doesn't offer coupons of its own. If you have commercial insurance, Merz's co-pay program may lower your cost for brand Ampyra to as little as $0. It isn't for Medicare, Medicaid or other government plans. Call 1-855-866-9255.
How much does Ampyra cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. Ask your plan how it covers brand Ampyra and generic dalfampridine. People with limited income can apply for Extra Help.
Is Fampyra the same as Ampyra?
Fampyra is the name used outside the U.S., including in Canada, for the same medicine: 10 mg extended-release tablets of fampridine, another name for dalfampridine. Merz sells it in both countries.
Sources
- Texas DSHS: 2026 annual WAC report (Ampyra 10 mg, 60 tablets (NDC 10144042760), $4,469.76; generic dalfampridine list prices (CivicaScript, Aurobindo, Actavis, Micro Labs, Accord, Ascend, Sun))
- AMPYRA U.S. prescribing information (DailyMed) (Merz Pharmaceuticals, label version 22, effective January 16, 2026)
- Drugs@FDA: Ampyra (NDA 022250) (10 mg extended-release tablet, Prescription, TE code AB; approved January 22, 2010)
- FDA Orange Book: dalfampridine products
- Drugs@FDA: Aurobindo dalfampridine (ANDA 206811) (approved January 23, 2017)
- FDA NDC Directory: Aurobindo dalfampridine 10 mg (NDC 65862-863) (ANDA 206811, marketing start June 25, 2018)
- FDA NDC Directory: CivicaScript dalfampridine 10 mg (NDC 82249-702) (ANDA 206765, marketing start July 21, 2025)
- Ampyra.com: cost and patient assistance (co-pay as little as $0; commercial insurance only; checked 2026-11-11)
- Health Canada Drug Product Database: Fampyra (Merz Therapeutics; 10 mg extended-release (DIN 02379910) Marketed)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.