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Zituvio Cost, Generic and Savings

U.S. list price
$947.16 for 90 days (90 tablets)The maker's price for brand Zituvio before discounts · Source: Texas DSHS 2026 WAC report
Lowest international online pharmacy price
Not available
See all Zituvio prices

Prices checked Nov 11, 2026 · Page updated November 12, 2026 · By the eDrugSearch team · How we check pharmacies and prices

Quick answerBrand Zituvio lists at $315.72 for 30 tablets in the U.S., any strength. Zydus's authorized generic lists at $80 for 30. We found no brand Zituvio offers from the pharmacies we compare in our latest check.

Name check: Zituvio contains sitagliptin in a different chemical form from Januvia and isn't rated interchangeable with it, so Januvia prices aren't mixed in here.

Compare Zituvio prices from licensed online pharmacies

In our latest check, we found no licensed online pharmacy abroad selling this medicine.

Jump to: U.S. cost · Medicare · Coupons & savings · Generic Zituvio · Similar drugs · Uses · FAQ

Zituvio (sitagliptin) 25, 50 and 100 mg tablets for type 2 diabetes, taken once a day. Zydus also sells a lower-priced authorized generic.

Zituvio cost at a glance

  • U.S. list price: $315.72 for 30 tablets of brand Zituvio, any strength, or $947.16 for 90 days (Texas DSHS). That's the maker's wholesale price before discounts, and pharmacies may charge more.
  • Authorized generic: Zydus also sells its own sitagliptin tablets made under Zituvio's FDA approval, listed since November 30, 2023 (FDA drug listing). Its U.S. list price is $80 for 30 tablets or $240 for 90, any strength (Texas DSHS). Ask your pharmacist for the cash price.
  • Not the same as Januvia: Zituvio uses sitagliptin free base, while Januvia uses sitagliptin phosphate. The FDA approved Zituvio under its own application and doesn't rate the two as interchangeable (FDA Orange Book).
  • From online pharmacies abroad: we found no brand Zituvio offers that met our listing rules in our latest check.
  • With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).

How much does Zituvio cost in the U.S.?

If you haveWhat Zituvio costsSource
No insurance (list price)$315.72 for 30 tablets of brand Zituvio, any strength. Pharmacies may charge more.Texas DSHS 2026 WAC report
No insurance (authorized generic)$80 for 30 tablets or $240 for 90 tablets of Zydus's sitagliptin, any strength (list price). Ask your pharmacist for the cash price.Texas DSHS 2026 WAC report
Private or employer insuranceYour copay depends on your plan's drug list and whether it covers brand Zituvio or Zydus's authorized generic.FDA drug listing
Medicare Part DYour cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100.Medicare.gov
MedicaidYour state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office.Medicaid.gov

Zydus lists brand Zituvio at $315.72 for 30 tablets of any strength, and its own authorized generic sitagliptin at $80 for 30 tablets (Texas DSHS). These are list prices (the maker's wholesale price before discounts); what a pharmacy charges can differ.

Zituvio cost with Medicare in 2026

In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Zituvio or its authorized generic depends on your plan's drug list.

Medicare Part DWhat Zituvio costsSource
Part D deductibleNo Medicare drug plan may have a deductible above $615 in 2026. Some plans have none.Medicare.gov
Yearly out-of-pocket capOnce your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year.Medicare.gov

Zituvio coupons and savings programs

How do you pay?

We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.

eDrugSearch does not offer its own Zituvio coupons. These programs can help with the cost of Zituvio:

  • Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
  • Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)

Is there a generic Zituvio?

Yes, an authorized generic. Zydus sells sitagliptin tablets (25, 50 and 100 mg) made under Zituvio's own FDA approval, listed as on the market since November 30, 2023. The FDA Orange Book lists no other generic of Zituvio. Generic Januvia (sitagliptin phosphate) is a different product.

StrengthU.S. genericMakersSince
25 mgYesZydus, authorized genericNov 30, 2023
50 mgYesZydus, authorized genericNov 30, 2023
100 mgYesZydus, authorized genericNov 30, 2023

Outside the U.S.: We found no Zituvio, and no version of it made for other markets, at the pharmacies we check.

Source: FDA drug listing: Zydus sitagliptin (NDA authorized generic). As of Nov 11, 2026.

Compare Zituvio with similar drugs

Other type 2 diabetes medicines people often compare with Zituvio, including Januvia and generic sitagliptin phosphate, and Tradjenta, another DPP-4 inhibitor. Prices are for each drug's lowest-priced strength.

DrugTypeLowest price we foundLink
JanuviasitagliptinType 2 diabetes medicine (DPP-4 inhibitor)$53.53 for 90 daysSee prices
SitagliptinsitagliptinType 2 diabetes medicine (DPP-4 inhibitor), generic of Januvia$53.53 for 90 daysSee prices
TradjentalinagliptinType 2 diabetes medicine (DPP-4 inhibitor)$43.38 for 90 daysSee prices
Janumetsitagliptin and metforminType 2 diabetes medicine (DPP-4 inhibitor with metformin)$70.63 for 90 daysSee prices

Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.

What is Zituvio used for?

Zituvio (sitagliptin) is a DPP-4 inhibitor. According to its FDA label (DailyMed), it is used:

  • Along with diet and exercise, to improve blood sugar control in adults with type 2 diabetes.

Zituvio comes as 25 mg, 50 mg and 100 mg tablets in bottles of 30 and 90, taken once a day with or without food. The usual dose is 100 mg; the label lists the lower strengths for people with reduced kidney function. It isn't for type 1 diabetes and hasn't been studied in people with a history of pancreatitis. The label has no boxed warning. Your prescriber decides which medicine is right for you.

Is it safe to order Zituvio from Canada?

Many Americans do, but U.S. law and customs rules apply, and for Zituvio, compare the U.S. list price of Zydus's authorized generic before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027.

Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.

Frequently asked questions

How much does Zituvio cost without insurance?

The U.S. list price of brand Zituvio is $315.72 for 30 tablets of any strength. Zydus's authorized generic sitagliptin lists at $80 for 30 tablets or $240 for 90. Ask your pharmacist for the cash price.

Is there a generic Zituvio?

Yes. Zydus sells an authorized generic, sitagliptin tablets made under Zituvio's own FDA approval, listed since November 2023. Its list price is $80 for 30 tablets or $240 for 90. Ask your pharmacist whether it can fill your prescription.

Zituvio vs. Januvia: what's the difference?

Both contain sitagliptin and are taken once a day for type 2 diabetes. Zituvio uses sitagliptin free base and Januvia uses sitagliptin phosphate. The FDA approved Zituvio under its own application and doesn't rate the two as interchangeable, so your pharmacist can't swap one for the other without your prescriber.

Is Zituvio a generic of Januvia?

No. Zituvio was approved as a separate product, not as a generic Januvia. Generic sitagliptin phosphate tablets, rated equivalent to Januvia, are a different product.

Is there a Zituvio coupon?

eDrugSearch doesn't offer coupons of its own. Zydus's authorized generic lists at $80 for 30 tablets. If you have Medicare and limited income, Extra Help can lower what you pay for prescriptions.

How much does Zituvio cost with Medicare?

It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help.

Sources

eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.