Generic Trintellix (vortioxetine) Price

Vortioxetine price by strength

Vortioxetine names

- Brand name: Trintellix (Takeda (developed with Lundbeck))
- Generic name: vortioxetine
- Names in Canada: Trintellix, plus generics such as Apo-Vortioxetine (Health Canada Drug Product Database, marketed products, checked Oct 29, 2026)
- Other names: Brintellix (U.K., Europe and some other countries)

Vortioxetine packs made for other countries are not FDA-approved.

Vortioxetine FAQ

Brand vs. generic: cost for 90 days

Lowest in this comparison: Brand Trintellix 10 mg from licensed pharmacies abroad.

90 days = 90 tablets of 10 mg. Generic sold abroad is not FDA-approved and is not in this box. Your price with insurance or Medicare depends on your plan.

See brand Trintellix prices

Vortioxetine cost with Medicare in 2026

Each Part D plan has its own list of covered drugs and copays (Medicare Plan Finder). No FDA-approved generic vortioxetine is sold in the U.S. yet. Check how your plan covers brand Trintellix; the Trintellix page has Medicare details. In 2026, Part D plans can have a yearly deductible of up to $615, and your out-of-pocket costs for covered drugs are capped at $2,100 a year ($2,400 in 2027) (Medicare.gov).

Savings programs from the maker

eDrugSearch does not offer its own Vortioxetine coupons. Maker savings and assistance programs are for brand Trintellix only, not generic vortioxetine from abroad (see the Trintellix page). eDrugSearch has no coupons of its own. These programs can lower prescription costs if you have Medicare:

• Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
• Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)

When people choose brand Trintellix

Some people get brand Trintellix instead of generic vortioxetine. Common reasons:

• In the U.S., vortioxetine is sold only as brand Trintellix. The Trintellix page shows U.S. prices, prices abroad and the maker's savings programs.
• Some insurance and Medicare drug plans cover brand Trintellix. Your plan's drug list shows whether it does and what you pay.

Your prescriber decides which medicine is right for you.

Compare prices for your other medicines

• Trintellix prices from $82.55 for 90 days
• Pristiq prices from $42.32 for 90 days
• Fetzima prices from $438.79 for 90 days

Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength.

What is Vortioxetine used for?

Vortioxetine is the active ingredient in Trintellix. Trintellix (vortioxetine) is an antidepressant. According to its FDA label (DailyMed), it is used to:

• Treat major depressive disorder (MDD) in adults.

Trintellix comes as 5 mg, 10 mg and 20 mg tablets. It is not approved for children. Like other antidepressants, its label has a boxed warning about an increased risk of suicidal thoughts and behaviors in children and young adults. Your prescriber decides which medicine is right for you. If you are in crisis, call or text 988.