Quick answerSymbravo's U.S. list price is $1,150.02 for a bottle of 9 tablets. No generic is sold, and Axsome offers a savings card for people with commercial insurance. We found no Symbravo offers from the pharmacies we compare in our latest check.

Name check: Symbravo can't be swapped for separate meloxicam and rizatriptan pills; its label says they aren't interchangeable, even at the same strengths.

Compare Symbravo prices from licensed online pharmacies

In our latest check, we found no licensed online pharmacy abroad selling this medicine.

Jump to: U.S. cost · Medicare · Coupons & savings · Generic Symbravo · Similar drugs · Uses · FAQ

Symbravo (meloxicam 20 mg and rizatriptan 10 mg) is a one-tablet treatment for migraine attacks, taken as needed. No generic is sold in the U.S.

Symbravo cost at a glance

  • U.S. list price: $1,150.02 for a bottle of 9 tablets of Symbravo (the maker's wholesale price before discounts, Texas DSHS). Pharmacies may charge more.
  • With private insurance: eligible patients may pay as little as $0 a month with the SYMBRAVO OnMySide Savings Program. It's not for Medicare, Medicaid or other government-funded insurance (Axsome).
  • How we compare: we list each pharmacy's packs as sold and compare the price per tablet. Symbravo is taken only when a migraine starts, no more than one tablet a day, so there is no daily dose. Your prescription says how many tablets you get.
  • No generic: the FDA Orange Book lists only Axsome's brand Symbravo and no generic (FDA Orange Book).
  • From online pharmacies abroad: we found no brand Symbravo offers that met our listing rules in our latest check.
  • With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).

How much does Symbravo cost in the U.S.?

If you haveWhat Symbravo costsSource
No insurance (list price)$1,150.02 for a bottle of 9 tablets of brand Symbravo. Pharmacies may charge more.Texas DSHS 2026 WAC report
Private or employer insuranceEligible patients may pay as little as $0 a month with the SYMBRAVO OnMySide Savings Program. Call 866-496-2976.Axsome
Medicare Part DYour cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. The savings program can't be used.Medicare.gov
MedicaidYour state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office.Medicaid.gov

Symbravo's U.S. list price is $1,150.02 for a bottle of 9 tablets (Texas DSHS). This is the maker's wholesale price before discounts; what a pharmacy charges can differ. No generic Symbravo is sold in the U.S.

Symbravo cost with Medicare in 2026

In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Symbravo depends on your plan's drug list. The Symbravo savings program can't be used with Medicare.

Medicare Part DWhat Symbravo costsSource
Part D deductibleNo Medicare drug plan may have a deductible above $615 in 2026. Some plans have none.Medicare.gov
Yearly out-of-pocket capOnce your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year.Medicare.gov

Symbravo coupons and savings programs

How do you pay?

We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.

eDrugSearch does not offer its own Symbravo coupons. These are the programs we could verify for Symbravo:

  • SYMBRAVO OnMySide Savings Program: for people with commercial insurance only. Eligible patients may pay as little as $0 a month. Not available to people with Medicare, Medicaid or other government-funded insurance. Call 866-496-2976. (Symbravo savings)
  • Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
  • Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)

Is there a generic Symbravo?

No. The FDA Orange Book lists only Axsome's brand Symbravo (meloxicam 20 mg and rizatriptan 10 mg), approved January 30, 2025, and no generic. Generic meloxicam and generic rizatriptan are sold separately, but the label says they can't be substituted for Symbravo.

StrengthU.S. genericMakersSince
20/10 mgNo—

Outside the U.S.: We found no Symbravo, and no version of it made for other markets, at the pharmacies we check.

Source: FDA Orange Book: Symbravo (NDA 215431). As of Nov 11, 2026.

Compare Symbravo with similar drugs

Other migraine medicines taken when an attack starts, with price pages here. Maxalt contains rizatriptan, one of Symbravo's two ingredients. Prices are for each drug's lowest-priced strength.

DrugTypeLowest price we foundLink
MaxaltrizatriptanMigraine medicine (triptan)From $1.64 per tabletSee prices
Nurtec ODTrimegepantMigraine medicine (CGRP receptor antagonist, or "gepant")From $26.04 per tabletSee prices
UbrelvyubrogepantAcute migraine medicine (CGRP receptor antagonist, or "gepant")From $21.00 per tabletSee prices
RelpaxeletriptanMigraine medicine (triptan)From $2.80 per tabletSee prices

Lowest price per unit, before shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.

What is Symbravo used for?

Symbravo combines meloxicam, a nonsteroidal anti-inflammatory drug (NSAID), with rizatriptan, a triptan migraine medicine. According to its FDA label (DailyMed), it is used:

  • To treat a migraine attack, with or without aura, in adults once it starts. It is not for preventing migraines or for cluster headache.

Each tablet holds 20 mg of meloxicam and 10 mg of rizatriptan. The label's dose is one tablet as needed, no more than one tablet a day, and the safety of treating more than 7 headaches in 30 days, on average, hasn't been established. U.S. bottles hold 9 tablets. Boxed warning: like other NSAIDs, Symbravo raises the risk of heart attack and stroke and of stomach bleeding, ulcers and tears, which can be fatal. Your prescriber decides which medicine is right for you.

Is it safe to order Symbravo from Canada?

Many Americans do, but U.S. law and customs rules apply, and for Symbravo, compare Axsome's savings program if you have commercial insurance before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027.

Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.

Frequently asked questions

How much does Symbravo cost without insurance?

The U.S. list price is $1,150.02 for a bottle of 9 tablets. With commercial insurance, eligible patients may pay as little as $0 a month with the SYMBRAVO OnMySide Savings Program.

Is there a Symbravo coupon or savings card?

Yes, for people with commercial insurance. With the SYMBRAVO OnMySide Savings Program, eligible patients may pay as little as $0 a month. It's not available with Medicare, Medicaid or other government-funded insurance. Call 866-496-2976. eDrugSearch doesn't offer coupons of its own.

Is there a generic Symbravo?

No. The FDA Orange Book lists only the brand. Generic meloxicam and rizatriptan are sold separately, but Symbravo's label says they can't be substituted for it.

Can I take meloxicam and rizatriptan instead of Symbravo?

Symbravo's label says its tablets aren't interchangeable with other meloxicam or rizatriptan products, even at the same strengths, because they haven't shown the same levels in the body. Your prescriber decides which medicine is right for you.

How much does Symbravo cost with Medicare?

It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. The savings program can't be used with Medicare, but people with limited income can apply for Extra Help.

How many Symbravo tablets can you take?

The label's dose is one tablet as needed for a migraine attack, and no more than one tablet a day. That's why this page compares prices per tablet.

Sources

eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.