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Restasis Price (cyclosporine ophthalmic emulsion)

As of Nov 5, 2026, brand Restasis 0.05% costs from $276.67 for 90 days at licensed pharmacies abroad (ships from India; packs made for other countries are not FDA-approved), vs. $1,936.89 at the U.S. list price.

Lowest U.S. online pharmacy price
$11.37 per vial$2,051 for 90 days (180 vials), shipping included · FDA-approved brand Restasis 0.05% · ships within the U.S.
Lowest international online pharmacy price
$1.45 per vial$276.67 for 90 days (180 vials), shipping included · brand Restasis 0.05%, not FDA-approved · ships from India

FDA-approved generic cyclosporine ophthalmic emulsion 0.05% from $166.28 for 90 days at U.S. pharmacies · See cyclosporine ophthalmic emulsion prices

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Prices checked Nov 5, 2026 · Page updated November 11, 2026 · By the eDrugSearch team · How we check pharmacies and prices

Name check: Cequa (cyclosporine 0.09%) and Vevye (cyclosporine 0.1%) are different cyclosporine eye products with their own strengths and formulas, not generics of Restasis.

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For comparison U.S. pharmacy list price: $1,936.89 for 90 days ($10.76 per vial), brand Restasis before insurance. The prices below are from U.S. pharmacies that publish cash prices and from licensed online pharmacies outside the U.S.

PharmacyMedicationPriceShipping & deliveryTotal (90 days)Buy
Licensed U.S. pharmacy ACyclosporine ophthalmic emulsion0.05% · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 7, 2026$161.03for 180 vials$0.89 per vial$5.25Delivery time not stated$166.28 for 90 days= $166.28 for 90 daysSave 91%incl. $5.25 shippingChecked Nov 7See pharmacy (members) Members see the pharmacy
Licensed U.S. pharmacy BCyclosporine ophthalmic emulsion0.05% · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Oct 29, 2026$70per 60 vials · 3 packs = $210$1.17 per vialFreePharmacy's estimate: 2–5 days$210 for 90 days= $210 for 90 daysSave 89%incl. $0 shippingChecked Oct 29See pharmacy (members) Members see the pharmacy
Online pharmacy CBrand Restasis 0.05%0.05% · brand · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Allergan$130.86per 90 vials · 2 packs = $261.72$1.45 per vial$14.95Pharmacy's estimate: 4–6 weeks$276.67 for 90 days= $276.67 for 90 daysSave 86%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy DRestasis 0.05%0.05% · brand · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Allergan India Pvt Ltd$132.82per 90 vials · 2 packs = $265.64$1.48 per vial$14.95Pharmacy's estimate: 4–6 weeks$280.59 for 90 days= $280.59 for 90 daysSave 86%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed U.S. pharmacy ECyclosporine 0.05% Ophthalmic Emulsion- 60x0.4ml Single Dose Vials0.05% · genericMaker listed by pharmacy: Mylan Pharmaceuticals Inc.Ships from United StatesShips within the U.S. (no customs) · checked Nov 7, 2026$93.84per 60 vials · 3 packs = $281.52$1.56 per vial$5Pharmacy's estimate: 2–8 business days$286.52 for 90 days= $286.52 for 90 daysSave 85%incl. $5 shippingChecked Nov 7See pharmacy (members) Members see the pharmacy
Online pharmacy FBrand Restasis 0.05%0.05% · brand · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Allergan$136.10per 90 vials · 2 packs = $272.20$1.51 per vial$14.95Pharmacy's estimate: 4–6 weeks$287.15 for 90 days= $287.15 for 90 daysSave 85%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy GBrand Restasis 0.05%0.05% · brand · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Allergan$140.68per 90 vials · 2 packs = $281.36$1.56 per vial$14.95Pharmacy's estimate: 4–6 weeks$296.31 for 90 days= $296.31 for 90 daysSave 85%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy CGeneric equivalent to Restasis 0.05%Not FDA-approved0.05% · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Lupin Ltd$14.33per 9 vials · 20 packs = $286.60$1.59 per vial$14.95Pharmacy's estimate: 4–6 weeks$301.55 for 90 days= $301.55 for 90 daysSave 84%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy CBrand Restasis 0.05%0.05% · brand · Filled in TurkeyMade for sale in Turkey.Maker listed by pharmacy: Allergan$152.59per 90 vials · 2 packs = $305.18$1.70 per vial$14.95Pharmacy's estimate: 4–6 weeks$320.13 for 90 days= $320.13 for 90 daysSave 83%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed U.S. pharmacy HCyclosporine (Restasis)0.05% · genericMaker listed by pharmacy: Maker not listedShips from United StatesShips within the U.S. (no customs) · checked Nov 5, 2026$321for 180 vials$1.78 per vialFreePharmacy's estimate: 7–10 business days$321 for 90 days= $321 for 90 daysSave 83%incl. $0 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy FBrand Restasis 0.05% (1X0.4ml)0.05% · brand · Filled in TurkeyMade for sale in Turkey.Maker listed by pharmacy: Allergan$153.50per 90 vials · 2 packs = $307$1.71 per vial$14.95Pharmacy's estimate: 4–6 weeks$321.95 for 90 days= $321.95 for 90 daysSave 83%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy GBrand Restasis 0.05% (1X0.4ml)0.05% · brand · Filled in TurkeyMade for sale in Turkey.Maker listed by pharmacy: Allergan$158.04per 90 vials · 2 packs = $316.08$1.76 per vial$14.95Pharmacy's estimate: 4–6 weeks$331.03 for 90 days= $331.03 for 90 daysSave 83%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy FGeneric equivalent to Restasis 0.05%Not FDA-approved0.05% · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Lupin Ltd$22.83per 12 vials · 15 packs = $342.45$1.90 per vial$14.95Pharmacy's estimate: 4–6 weeks$357.40 for 90 days= $357.40 for 90 daysSave 82%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy GGeneric equivalent to Restasis 0.05%Not FDA-approved0.05% · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Lupin Ltd$23.20per 12 vials · 15 packs = $348$1.93 per vial$14.95Pharmacy's estimate: 4–6 weeks$362.95 for 90 days= $362.95 for 90 daysSave 81%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy IRestasis Eye Drops 0.05% Solution0.05% · brand · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Allergan$187.99per 90 vials · 2 packs = $375.98$2.09 per vialFreePharmacy's estimate: 2–3 weeks$375.98 for 90 days= $375.98 for 90 daysSave 81%incl. $0 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy JRestasis Eye Drop 0.05% Solution0.05% · brand · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Allergan Inc.$377.52for 180 vials$2.10 per vial$9.95Pharmacy's estimate: 4–6 weeks$387.47 for 90 days= $387.47 for 90 daysSave 80%incl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy JCyclosporine Vials 0.05% Solution (United States pack, ships from Canada)Not FDA-approved0.05% · generic · Filled in CanadaMaker listed by pharmacy: Teva PharmaceuticalsMade for United States$390for 180 vials$2.17 per vial$9.95Pharmacy's estimate: 4–6 weeks$399.95 for 90 days= $399.95 for 90 daysSave 79%incl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy ICyclosporine Unit Dose Eye Drops 0.05% SolutionNot FDA-approved0.05% · generic · Filled in CanadaMaker listed by pharmacy: Teva$236.50per 90 vials · 2 packs = $473$2.63 per vialFreePharmacy's estimate: 2–3 weeks$473 for 90 days= $473 for 90 daysSave 76%incl. $0 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy DCiclosporin 0.05%Not FDA-approved0.05% · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Lupin Ltd$24.43per 9 vials · 20 packs = $488.60$2.71 per vial$14.95Pharmacy's estimate: 4–6 weeks$503.55 for 90 days= $503.55 for 90 daysSave 74%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy KCyclosporine Unit Dose Eye DropsNot FDA-approved0.05% · generic · Filled in CanadaMaker listed by pharmacy: Teva Pharma$269.56per 90 vials · 2 packs = $539.12$3.00 per vial$9.95Pharmacy's estimate: 3–6 weeks$549.07 for 90 days= $549.07 for 90 daysSave 72%incl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy LRestasis 0.05% Solution0.05% · brand · Filled in CanadaMaker listed by pharmacy: Maker not shown by pharmacy$628.76for 180 vials$3.49 per vialFee not publishedDelivery time not stated$628.76 for 90 days= $628.76 for 90 days+ shippingSave 68%incl. $0 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy DRestasis 0.05% (Turkey pack, ships from Mauritus)0.05% · brand · Filled in MauritusMaker listed by pharmacy: AllerganMade for Turkey$346.93per 90 vials · 2 packs = $693.86$3.85 per vial$14.95Pharmacy's estimate: 4–6 weeks$708.81 for 90 days= $708.81 for 90 daysSave 63%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed U.S. pharmacy ECyclosporine 0.05% Ophthalmic Emulsion- 30x0.4ml Single Dose Vials0.05% · genericMaker listed by pharmacy: Lupin Pharmaceuticals, Inc.Ships from United StatesShips within the U.S. (no customs) · checked Nov 5, 2026$122.40per 30 vials · 6 packs = $734.40$4.08 per vial$5Pharmacy's estimate: 2–8 business days$739.40 for 90 days= $739.40 for 90 daysSave 62%incl. $5 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy IRestasis Eye Drops 0.05% Solution0.05% · brand · Filled in CanadaMaker listed by pharmacy: Abbvie Corp.$434.19per 90 vials · 2 packs = $868.38$4.82 per vialFreePharmacy's estimate: 2–3 weeks$868.38 for 90 days= $868.38 for 90 daysSave 55%incl. $0 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy JRestasis Eye Drop 0.05% Solution0.05% · brand · Filled in CanadaMaker listed by pharmacy: Allergan Inc.$450per 90 vials · 2 packs = $900$5.00 per vial$9.95Pharmacy's estimate: 4–6 weeks$909.95 for 90 days= $909.95 for 90 daysSave 53%incl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy KRestasis Eye Drops0.05% · brand · Filled in CanadaMaker listed by pharmacy: ABBVIE CORPORATION$451.05per 90 vials · 2 packs = $902.10$5.01 per vial$9.95Pharmacy's estimate: 3–6 weeks$912.05 for 90 days= $912.05 for 90 daysSave 53%incl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy FBrand Restasis 0.05% (30x0.4ml)0.05% · brand · Filled in CanadaMaker listed by pharmacy: Allergan Inc$470.73per 90 vials · 2 packs = $941.46$5.23 per vial$14.95Pharmacy's estimate: 4–6 weeks$956.41 for 90 days= $956.41 for 90 daysSave 51%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy GBrand Restasis 0.05% (1x0.4ml)0.05% · brand · Filled in CanadaMaker listed by pharmacy: Allergan Inc$515.80per 90 vials · 2 packs = $1,031.60$5.73 per vial$14.95Pharmacy's estimate: 4–6 weeks$1,046.55 for 90 days= $1,046.55 for 90 daysSave 46%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy MRestasis single-use vials0.05% · brand · Filled in CanadaMaker listed by pharmacy: Allergan$172.60per 30 vials · 6 packs = $1,035.60$5.75 per vial$14.99Delivery time not stated$1,050.59 for 90 days= $1,050.59 for 90 daysSave 46%incl. $14.99 shippingChecked Oct 25See pharmacy (members) Members see the pharmacy
Online pharmacy CBrand Restasis 0.05% (30x0.4ml)0.05% · brand · Filled in CanadaMaker listed by pharmacy: Allergan Inc$541.59per 90 vials · 2 packs = $1,083.18$6.02 per vial$14.95Pharmacy's estimate: 4–6 weeks$1,098.13 for 90 days= $1,098.13 for 90 daysSave 43%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed U.S. pharmacy ERestasis 0.05% Eye Emulsion (30 Dropper Pack)0.05% · brandMaker listed by pharmacy: Allergan, Inc.Ships from United StatesShips within the U.S. (no customs) · checked Nov 5, 2026$1,023per 90 vials · 2 packs = $2,046$11.37 per vial$5Pharmacy's estimate: 2–8 business days$2,051 for 90 days= $2,051 for 90 daysincl. $5 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed U.S. pharmacy HRestasis • [Brand]0.05% · brandMaker listed by pharmacy: Maker not listedShips from United StatesShips within the U.S. (no customs) · checked Nov 5, 2026$686per 60 vials · 3 packs = $2,058$11.43 per vialFreePharmacy's estimate: 7–10 business days$2,058 for 90 days= $2,058 for 90 daysincl. $0 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed U.S. pharmacy ERestasis 0.05% Single Use Droppers (0.4ml) - 60ct0.05% · brandMaker listed by pharmacy: Allergan, Inc.Ships from United StatesShips within the U.S. (no customs) · checked Nov 5, 2026$703per 60 vials · 3 packs = $2,109$11.72 per vial$5Pharmacy's estimate: 2–8 business days$2,114 for 90 days= $2,114 for 90 daysincl. $5 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy LRestasis Multidose 0.05% Solution0.05% · brand · Filled in CanadaMaker listed by pharmacy: Maker not shown by pharmacy$391.46per 14 vials · 13 packs = $5,088.98$27.96 per vialFee not publishedDelivery time not stated$5,088.98 for 91 days= $5,033.06 for 90 days+ shippingWorked out from a 91-day orderChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy KRestasis Eye Drop Multidose0.05% · brand · Filled in CanadaMaker listed by pharmacy: ABBVIE CORPORATION$296.95per 6 vials · 30 packs = $8,908.50$49.49 per vial$9.95Pharmacy's estimate: 3–6 weeks$8,918.45 for 90 days= $8,918.45 for 90 daysincl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy IRestasis Eye Drop Multidose 0.05% Solution0.05% · brand · Filled in CanadaMaker listed by pharmacy: Abbvie Corp.$303.79per 6 vials · 30 packs = $9,113.70$50.63 per vialFreePharmacy's estimate: 2–3 weeks$9,113.70 for 90 days= $9,113.70 for 90 daysincl. $0 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed U.S. pharmacy ERestasis 0.05% Multidose Drops- 5.5ml0.05% · brandMaker listed by pharmacy: Allergan, Inc.Ships from United StatesShips within the U.S. (no customs) · checked Nov 5, 2026$703per 6 vials · 30 packs = $21,090$117.17 per vial$5Pharmacy's estimate: 2–8 business days$21,095 for 90 days= $21,095 for 90 daysincl. $5 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy

Buying from a pharmacy outside the U.S.? Read Is it safe to order Restasis from Canada?

90-day cost = 180 vials at the usual dose of 2 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 5, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.

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90-day prices from 8 licensed pharmacies abroad shipping to the U.S.: $276.67 to $9,113.70, any strength, shipping included.

Jump to: Medicare · Maker savings · Generic Restasis · Similar drugs · Uses · FAQ

Restasis (cyclosporine 0.05%) eye drops for chronic dry eye, in single-use vials and a MultiDose bottle. FDA-approved generic vials are sold in the U.S.

Restasis price by strength

StrengthLowest brand90 daysLowest generic abroad90 days, not FDA-approvedPrice per vial
Restasis 0.05%$276.67$301.55$1.45 brand · $1.59 generic

Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per vial is for that lowest pack, before shipping. Prices checked Nov 5, 2026.

Cheapest ways to get Restasis 0.05%

The cheapest ways we found to get brand Restasis 0.05% (prices checked Nov 5, 2026). The lowest 90-day cost is shaded green.

Way to buyCostDetails
Licensed online pharmacy abroad$276.67 for 90 daysBrand Restasis 0.05%, ships from India, not FDA-approved (made for another country). Shipping included, checked Nov 5, 2026. See all prices
U.S. pharmacy cash price$2,051 for 90 daysFDA-approved brand Restasis 0.05%, ships within the U.S. (no customs). Shipping included, checked Nov 5, 2026. See all prices
U.S. list price$1,936.89 for 90 daysBrand Restasis before insurance. Pharmacies may charge more.
Medicare Part DDepends on your planYour plan’s drug list and coverage phase set your cost. Medicare costs

Costs abroad and at U.S. pharmacies are for one order closest to 90 days, shipping included, from the price table above. Programs set their own rules, so check the terms before you count on one.

How much does Restasis cost without insurance?

Without insurance, Restasis costs $645.63 for a 30-day supply at the U.S. list price, or about $1,936.89 for 90 days. Licensed pharmacies abroad charged from $276.67 for 90 days of brand Restasis 0.05% in our latest check (Nov 5, 2026), shipping included. Generic: Several companies sell FDA-approved generic cyclosporine 0.05% vials. Cash prices vary by pharmacy, so ask your pharmacy for its price (Drugs@FDA).

Restasis cost with Medicare

In 2026, a Medicare drug plan (Part D) can charge a deductible of up to $615, and once you've spent $2,100 out of pocket on covered drugs, you pay nothing more for covered drugs that year ($2,400 in 2027) (Medicare.gov). What you pay for Restasis depends on your plan's drug list and your coverage phase. If your income is limited, Extra Help lowers drug costs: in 2026 you pay no more than $5.10 for a generic and $12.65 for a brand-name drug, with income under $23,940 ($32,460 for a married couple) and resources under $18,090 ($36,100 for a couple) (CMS). The free Medicare Prescription Payment Plan spreads costs into monthly payments, but it doesn't lower the total.

Medicare Part DWhat Restasis costsSource
Part D deductible (2026)Up to $615 a year, depending on your planMedicare.gov
Part D out-of-pocket cap (2026)$2,100 a year for covered drugsMedicare.gov
Negotiated priceNone: Restasis is not on the 2026, 2027 or 2028 listsCMS
Limited incomeExtra Help can lower what you pay for prescriptionsSocial Security

Restasis cost with insurance

With private or employer insurance, what you pay for Restasis depends on your plan's drug list, deductible and copay. As little as $0 with the Restasis copay program, up to $1,200 in savings per calendar year. Not valid for cash-paying patients (AbbVie).

Medicaid: Your state Medicaid program sets coverage and copays. The Restasis copay program can't be used with Medicaid (AbbVie).

Restasis patient assistance program

AbbVie runs myAbbVie Assist. Who qualifies: People in the U.S. with limited or no health insurance coverage who meet income limits: household income of $77,280 or less for 1 person, $104,520 for 2, $131,760 for 3 or $159,000 for 4 (add $27,240 for each extra person). People with insurance may also be reviewed based on their coverage. We couldn't confirm on the program's own pages that Restasis is on its current list (checked 2026-10-29), so call 1-800-222-6885 to ask before you apply.

Is there a generic Restasis?

Partly. Generic cyclosporine 0.05% single-use vials are sold in the U.S.; the FDA approved the first one, from Mylan (now Viatris), on February 2, 2022. No generic of the Restasis MultiDose bottle is listed. The generic name is cyclosporine ophthalmic emulsion 0.05%. See generic Restasis (cyclosporine ophthalmic emulsion) prices.

StrengthU.S. genericMakersSince
0.05% single-use vialsYesMylan (Viatris), Teva, Devatis, Saptalis, Upsher-Smith, Jiangsu AnbisonFeb 2, 2022
0.05% MultiDose bottle (5.5 mL)No—

Outside the U.S.: In Canada, AbbVie sells Restasis and Restasis MultiDose under the same names. Outside the U.S., the ingredient is often spelled ciclosporin.

Source: Drugs@FDA: cyclosporine ophthalmic generic applications. As of Oct 25, 2026.

See generic cyclosporine ophthalmic emulsion prices

Restasis FAQ

What is the cost of a 30-day supply of Restasis?

AbbVie's U.S. list price is $645.63 for 60 single-use vials, about a 30-day supply, or $322.80 for 30 vials. As of Nov 5, 2026, brand Restasis 0.05% cost from $276.67 for 90 days at licensed pharmacies abroad we compared, shipping included. Pharmacies may charge more than list price.

What is the cost of generic Restasis?

Cash prices for generic cyclosporine 0.05% vials vary by U.S. pharmacy, so ask your pharmacy for its price. In our latest check (Nov 5, 2026), licensed pharmacies abroad charged $301.55 to $549.07 for 90 days of generic cyclosporine 0.05% vials, shipping included.

Is there a generic Restasis?

Yes, for single-use vials. The FDA approved the first generic cyclosporine 0.05% eye drop vials, from Mylan, in February 2022, and Drugs@FDA lists marketed generics from several companies, including Teva, Devatis, Saptalis, Upsher-Smith and Jiangsu Anbison. The FDA rates Mylan's generic as substitutable for Restasis vials. No generic of the Restasis MultiDose bottle is listed. See generic Restasis (cyclosporine eye drops) prices.

How much does Restasis cost without insurance?

Without insurance, Restasis costs $645.63 for a 30-day supply at the U.S. list price, or about $1,936.89 for 90 days.

Does Medicare cover Restasis?

It depends on your Part D plan's drug list. In 2026, a Medicare drug plan (Part D) can charge a deductible of up to $615, and once you've spent $2,100 out of pocket on covered drugs, you pay nothing more for covered drugs that year ($2,400 in 2027) (Medicare.gov). What you pay for Restasis depends on your plan's drug list and your coverage phase.

Is there a patient assistance program for Restasis?

AbbVie runs myAbbVie Assist. Who qualifies: People in the U.S. with limited or no health insurance coverage who meet income limits: household income of $77,280 or less for 1 person, $104,520 for 2, $131,760 for 3 or $159,000 for 4 (add $27,240 for each extra person). People with insurance may also be reviewed based on their coverage. We couldn't confirm on the program's own pages that Restasis is on its current list (checked 2026-10-29), so call 1-800-222-6885 to ask before you apply.

What is the difference between Restasis and Restasis MultiDose?

Both contain cyclosporine 0.05% and have the same FDA-approved use. Restasis comes in preservative-free single-use vials, and Restasis MultiDose is a preservative-free 5.5 mL bottle. Generics are sold only as single-use vials.

Brand vs. generic: cost for 90 days

Option90 days
Generic cyclosporine ophthalmic emulsion 0.05%, U.S. pharmacy cash priceLowest U.S. pharmacy price we found, checked Oct 29, 2026$166.28
Brand Restasis 0.05% from licensed pharmacies abroadLowest price we found, shipping included, checked Nov 5, 2026$276.67
Brand Restasis, U.S. list priceBefore insurance; pharmacies may charge more$1,936.89

Lowest in this comparison: Generic cyclosporine ophthalmic emulsion 0.05%, U.S. pharmacy cash price.

90 days = 180 vials of 0.05%. Generic sold abroad is not FDA-approved and is not in this box. Your price with insurance or Medicare depends on your plan.

Savings programs from the maker

How do you pay?

We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.

eDrugSearch does not offer its own Restasis coupons. These are the real savings programs, run by the drug's maker and by Medicare:

  • Restasis Savings Card: for people with private or employer insurance. Depending on coverage, eligible patients may pay as little as $0, with up to $1,200 in savings per calendar year. Not valid for Medicare, Medicaid, TRICARE or other federal or state programs, or for cash-paying patients. Questions: 1-844-469-8327. (Restasis savings)
  • Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
  • Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
  • Costco Pharmacy member prices: Costco publishes member prices for many prescriptions, for people with a Costco membership. Non-members can also use Costco pharmacies and pay the regular cash price. Member prices can't be used with insurance, Medicare or Medicaid claims. (Costco Pharmacy)
  • Amazon Pharmacy Prime and RxPass: Amazon Pharmacy offers Prime members discounts on many prescriptions, and RxPass, for Prime members, covers a set list of generics for a flat monthly fee. Prime is not required to use Amazon Pharmacy. Prime savings have limits for people with Medicare, Medicaid or Tricare, and RxPass is not open to people with Medicaid or CHIP. (Amazon Pharmacy)
  • Discount cards: Discount cards (for example GoodRx or SingleCare) may lower the price at local pharmacies; prices vary by pharmacy and ZIP code.

Compare Restasis with similar drugs

Other prescription dry eye medicines people often compare with Restasis, including Xiidra. Prices are for each drug's lowest-priced strength.

DrugTypeLowest price we foundLink
XiidralifitegrastDry eye medicine (LFA-1 antagonist eye drops)$1,048.04 for 90 daysSee prices
Cequacyclosporine ophthalmic solutionDry eye medicine (calcineurin inhibitor eye drops)$889.95 for 90 daysSee prices

Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.

What is Restasis used for?

Restasis (cyclosporine ophthalmic emulsion 0.05%) is a calcineurin inhibitor eye drop. According to its FDA label (DailyMed), it is used to:

  • Increase tear production in people whose tear production is thought to be reduced because of eye inflammation from chronic dry eye (keratoconjunctivitis sicca).

The label notes that more tear production was not seen in people using anti-inflammatory eye drops or punctal plugs. Restasis comes as 0.05% preservative-free single-use vials (0.4 mL, trays of 30 or 60) and a 5.5 mL MultiDose bottle. Your prescriber decides which medicine is right for you.

Is it safe to order Restasis from Canada?

Many Americans do, but U.S. law and customs rules apply, and for Restasis a U.S. generic may cost less. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, AbbVie sells Restasis and Restasis MultiDose under the same names.

Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.

Sources

eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.