Generic Motegrity (prucalopride) Price

Prucalopride price by strength

Prucalopride names

- Brand name: Motegrity (Takeda)
- Generic name: prucalopride
- Names in Canada: Generics such as Apo-Prucalopride, Jamp Prucalopride and Nra-Prucalopride (Health Canada Drug Product Database, marketed products, checked Oct 29, 2026)
- Other names: Resotran (brand name in Canada); Resolor (brand name in the U.K. and Europe)

Prucalopride packs made for other countries are not FDA-approved.

Prucalopride FAQ

Brand vs. generic: cost for 90 days

Lowest in this comparison: Generic prucalopride 2 mg, U.S. pharmacy cash price.

90 days = 90 tablets of 2 mg. Generic sold abroad is not FDA-approved and is not in this box. Your price with insurance or Medicare depends on your plan.

See brand Motegrity prices

Prucalopride cost with Medicare in 2026

Each Part D plan has its own list of covered drugs and copays, so what you pay for prucalopride depends on your plan (Medicare Plan Finder). In 2026, Part D plans can have a yearly deductible of up to $615, and your out-of-pocket costs for covered drugs are capped at $2,100 a year ($2,400 in 2027) (Medicare.gov).

Savings programs from the maker

eDrugSearch does not offer its own Prucalopride coupons. We could not confirm a current Takeda savings card for brand Motegrity. These programs can lower what you pay for generic prucalopride:

• Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
• Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
• Costco Pharmacy member prices: Costco publishes member prices for many prescriptions, for people with a Costco membership. Non-members can also use Costco pharmacies and pay the regular cash price. Member prices can't be used with insurance, Medicare or Medicaid claims. (Costco Pharmacy)
• Amazon Pharmacy Prime and RxPass: Amazon Pharmacy offers Prime members discounts on many prescriptions, and RxPass, for Prime members, covers a set list of generics for a flat monthly fee. Prime is not required to use Amazon Pharmacy. Prime savings have limits for people with Medicare, Medicaid or Tricare, and RxPass is not open to people with Medicaid or CHIP. (Amazon Pharmacy)
• Discount cards: Discount cards (for example GoodRx or SingleCare) may lower the price at local pharmacies; prices vary by pharmacy and ZIP code.

When people choose brand Motegrity

Some people get brand Motegrity instead of generic prucalopride. Common reasons:

• A prescription marked “dispense as written” (or “brand medically necessary”) tells the pharmacy to fill brand Motegrity, not a generic. State laws set the rules for generic substitution.
• Some insurance and Medicare drug plans cover the brand and the generic at different copays, or cover only one of them. Your plan's drug list shows which.

Your prescriber decides which medicine is right for you.

Compare prices for your other medicines

• Motegrity prices from $81.85 for 90 days
• Linzess prices from $317.52 for 90 days

Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength.

What is Prucalopride used for?

Prucalopride is a serotonin-4 (5-HT4) receptor agonist, the same medicine as in Motegrity. The FDA label for Motegrity (DailyMed), which the generic labels follow, lists this use:

• Treat chronic idiopathic constipation (CIC) in adults.

Prucalopride comes as 1 mg and 2 mg tablets taken once a day, with or without food. The label lists the 1 mg dose for adults with severe kidney impairment. The label has no boxed warning, but it warns about reports of suicidal thoughts and behavior and new or worsening depression. Check the label that comes with your medicine. Your prescriber decides which medicine is right for you. If you are in crisis, call or text 988.