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Mysoline Price, Generic and Savings
- Lowest U.S. online pharmacy price
- $84.17 per tablet$22,730.90 for 90 days (270 tablets), shipping included · FDA-approved brand Mysoline 250 mg · ships within the U.S.
- Lowest international online pharmacy price
- $0.42 per tablet$113.01 for 90 days (270 tablets), plus shipping (fee not published) · brand Mysoline 250 mg, not FDA-approved · ships from Australia
FDA-approved generic primidone 250 mg from $42.80 for 90 days at U.S. pharmacies
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Quick answerAs of Nov 12, 2026, brand Mysoline 250 mg costs from $170.22 for 90 days at online pharmacies abroad we compared, vs. $20,313.07 at the U.S. list price ($7,523.36 for 100 tablets). Generic primidone 250 mg lists from $29.11 for 100.
Name check: This page is for Mysoline tablets (primidone), 50 mg and 250 mg. Generic primidone 125 mg packs are shown too. Prices count 3 tablets a day, the label's usual maintenance dose.
Compare Mysoline prices from licensed online pharmacies
For comparison U.S. pharmacy list price: $20,313.06 for 90 days ($75.23 per tablet), brand Mysoline 250 mg before insurance. The prices below are from U.S. pharmacies that publish cash prices and from licensed online pharmacies outside the U.S.
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per tabletOnline pharmacy A | PrimidoneNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.125 mg · generic · Filled in CanadaProduct of Canada | $22.82for 200 tablets$0.11 per tablet | Fee not publishedDelivery time not stated | $22.82 for 67 days= $30.81 for 90 days+ shippingWorked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy A | PrimidoneNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.250 mg · generic · Filled in CanadaProduct of Canada | $30.96for 200 tablets$0.15 per tablet | Fee not publishedDelivery time not stated | $30.96 for 67 days= $41.80 for 90 days+ shippingSave 100%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy B | Primidone 250mg Tablets250 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 12, 2026 | $37.80for 270 tablets$0.14 per tablet | $5Pharmacy's estimate: 2–8 business days | $42.80 for 90 days= $42.80 for 90 daysSave 100%incl. $5 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | PrimidoneNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.125 mg · generic · Filled in CanadaProduct of Canada | $33.99for 200 tablets$0.17 per tablet | Fee not publishedDelivery time not stated | $33.99 for 67 days= $45.89 for 90 days+ shippingWorked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | PrimidoneNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.250 mg · generic · Filled in CanadaProduct of Canada | $41.99for 200 tablets$0.21 per tablet | Fee not publishedDelivery time not stated | $41.99 for 67 days= $56.69 for 90 days+ shippingSave 100%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy D | Primidone (Mysoline)50 mg · genericMaker listed by pharmacy: Oxford PharmaShips from United StatesShips within the U.S. (no customs) · checked Nov 12, 2026 | $21.20per 90 tablets · 3 packs = $63.60$0.24 per tablet | FreePharmacy's estimate: 7–10 business days | $63.60 for 90 days= $63.60 for 90 daysincl. $0 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | PrimidoneNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.125 mg · generic · Filled in CanadaProduct of Canada | $49.90for 200 tablets$0.25 per tablet | $9.95Delivery time not stated | $59.85 for 67 days= $80.80 for 90 daysWorked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy F | Generic Mysoline 250mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.250 mg · generic · Filled in IndiaMade for sale in India.Product of India | $30.69per 90 tablets · 3 packs = $92.07$0.34 per tablet | Fee not publishedDelivery time not stated | $92.07 for 90 days= $92.07 for 90 days+ shippingSave 100%incl. $0 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | PrimidoneNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.250 mg · generic · Filled in CanadaProduct of Canada | $62.36for 200 tablets$0.31 per tablet | $9.95Delivery time not stated | $72.31 for 67 days= $97.62 for 90 daysSave 100%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy G | PrimidoneNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.250 mg · generic · Filled in CanadaProduct of Canada | $66for 200 tablets$0.33 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $75.95 for 67 days= $102.53 for 90 daysSave 99%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy B | Primidone 50mg Tablets50 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 12, 2026 | $33.30per 90 tablets · 3 packs = $99.90$0.37 per tablet | $5Pharmacy's estimate: 2–8 business days | $104.90 for 90 days= $104.90 for 90 daysincl. $5 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy D | Primidone (Mysoline)250 mg · genericMaker listed by pharmacy: Oxford PharmaShips from United StatesShips within the U.S. (no customs) · checked Nov 12, 2026 | $36.90per 90 tablets · 3 packs = $110.70$0.41 per tablet | FreePharmacy's estimate: 7–10 business days | $110.70 for 90 days= $110.70 for 90 daysSave 99%incl. $0 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy A | Mysoline250 mg · brand · Filled in AustraliaProduct of Australia | $83.71for 200 tablets$0.42 per tablet | Fee not publishedDelivery time not stated | $83.71 for 67 days= $113.01 for 90 days+ shippingSave 99%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | Mysoline250 mg · brand · Filled in AustraliaProduct of Australia | $94.99for 200 tablets$0.47 per tablet | Fee not publishedDelivery time not stated | $94.99 for 67 days= $128.24 for 90 days+ shippingSave 99%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed Canadian pharmacy H | PrimidoneNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.250 mg · generic · Filled in CanadaMaker listed by pharmacy: AA Pharma Inc | $49.27per 100 tablets · 2 packs = $98.54$0.49 per tablet | $9.95Pharmacy's estimate: 3–6 weeks | $108.49 for 67 days= $146.46 for 90 daysSave 99%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy I | MYSOLINE (India pack, ships from Mauritius)250 mg · brand · Filled in MauritiusProduct of India | $126.09for 200 tablets$0.63 per tablet | FreeDelivery time not stated | $126.09 for 67 days= $170.22 for 90 daysSave 99%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy J | MYSOLINE (India pack, ships from Mauritius)250 mg · brand · Filled in MauritiusProduct of India | $128.48for 200 tablets$0.64 per tablet | FreeDelivery time not stated | $128.48 for 67 days= $173.45 for 90 daysSave 99%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy K | Generic Equivalent To Mysoline 250mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.250 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Sun Pharmaceuticals | $58.92per 90 tablets · 3 packs = $176.76$0.65 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $191.71 for 90 days= $191.71 for 90 daysSave 99%incl. $14.95 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy I | MYSOLINE (UK pack, ships from Australia)250 mg · brand · Filled in AustraliaProduct of UK | $143.59for 200 tablets$0.72 per tablet | FreeDelivery time not stated | $143.59 for 67 days= $193.85 for 90 daysSave 99%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy J | MYSOLINE (UK pack, ships from Australia)250 mg · brand · Filled in AustraliaProduct of UK | $145.98for 200 tablets$0.73 per tablet | FreeDelivery time not stated | $145.98 for 67 days= $197.07 for 90 daysSave 99%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy L | PrimidoneNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.250 mg · generic · Filled in New ZealandProduct of New Zealand | $81.39per 100 tablets · 2 packs = $162.78$0.81 per tablet | FreePharmacy's estimate: 2–3 weeks | $162.78 for 67 days= $219.75 for 90 daysSave 99%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy M | Generic Equivalent To Mysoline 250mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.250 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Sun Pharmaceuticals | $46.08per 60 tablets · 4 packs = $184.32$0.77 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $199.27 for 80 days= $224.18 for 90 daysSave 99%Worked out from an 80-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | Mysoline250 mg · brand · Filled in AustraliaProduct of Australia | $167.25for 200 tablets$0.84 per tablet | $9.95Delivery time not stated | $177.20 for 67 days= $239.22 for 90 daysSave 99%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy L | PrimidoneNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.250 mg · generic · Filled in United KingdomProduct of United Kingdom | $99.99per 90 tablets · 3 packs = $299.97$1.11 per tablet | FreePharmacy's estimate: 2–3 weeks | $299.97 for 90 days= $299.97 for 90 daysSave 99%incl. $0 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy G | PrimidoneNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.50 mg · generic · Filled in United KingdomProduct of United Kingdom | $320for 200 tablets$1.60 per tablet | $9.95Pharmacy's estimate: 4–6 weeks | $329.95 for 67 days= $445.43 for 90 daysWorked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy E | Primidone (UK/EU pack, ships from United Kingdom)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.50 mg · generic · Filled in United KingdomProduct of UK/EU | $184.99per 100 tablets · 2 packs = $369.98$1.85 per tablet | $9.95Delivery time not stated | $379.93 for 67 days= $512.91 for 90 daysWorked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy L | PrimidoneNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.50 mg · generic · Filled in United KingdomProduct of United Kingdom | $200.51per 100 tablets · 2 packs = $401.02$2.01 per tablet | FreePharmacy's estimate: 2–3 weeks | $401.02 for 67 days= $541.38 for 90 daysWorked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy N | MYSOLINE 125MG TABLET 100 (GENERIC PRIMIDONE FROM UK)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.125 mg · generic · Filled in UKProduct of UK | $220per 100 tablets · 2 packs = $440$2.20 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $454.95 for 67 days= $614.18 for 90 daysWorked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy N | MYSOLINE 250MG TABLET 100 (GENERIC PRIMIDONE FROM UK)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.250 mg · generic · Filled in UKProduct of UK | $260per 100 tablets · 2 packs = $520$2.60 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $534.95 for 67 days= $722.18 for 90 daysSave 96%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy A | Primidone (UK/EU pack, ships from United Kingdom)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.50 mg · generic · Filled in United KingdomProduct of UK/EU | $332.24per 100 tablets · 2 packs = $664.48$3.32 per tablet | Fee not publishedDelivery time not stated | $664.48 for 67 days= $897.05 for 90 days+ shippingWorked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy N | MYSOLINE 50MG TABLET 100 (GENERIC PRIMIDONE FROM UK)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.50 mg · generic · Filled in UKProduct of UK | $330per 100 tablets · 2 packs = $660$3.30 per tablet | $14.95Pharmacy's estimate: 4–6 weeks | $674.95 for 67 days= $911.18 for 90 daysWorked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy C | Primidone (UK/EU pack, ships from United Kingdom)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.50 mg · generic · Filled in United KingdomProduct of UK/EU | $342.99per 100 tablets · 2 packs = $685.98$3.43 per tablet | Fee not publishedDelivery time not stated | $685.98 for 67 days= $926.07 for 90 days+ shippingWorked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy B | Mysoline 50mg Tablets50 mg · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 12, 2026 | $2,210.40per 90 tablets · 3 packs = $6,631.20$24.56 per tablet | $5Pharmacy's estimate: 2–8 business days | $6,636.20 for 90 days= $6,636.20 for 90 daysincl. $5 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletLicensed U.S. pharmacy B | Mysoline 250mg Tablets250 mg · brandU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 12, 2026 | $2,525.10per 30 tablets · 9 packs = $22,725.90$84.17 per tablet | $5Pharmacy's estimate: 2–8 business days | $22,730.90 for 90 days= $22,730.90 for 90 daysincl. $5 shippingChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy OU.S. shipping limited | Primidone (Generic)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.125 mg · generic · Filled in CanadaProduct of Canada | $120for 200 tablets$0.60 per tablet | $14.95Pharmacy's estimate: 8–14 business days | $134.95 for 67 days= $182.18 for 90 daysWorked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy OU.S. shipping limited | Primidone (Generic)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.250 mg · generic · Filled in CanadaProduct of Canada | $120for 200 tablets$0.60 per tablet | $14.95Pharmacy's estimate: 8–14 business days | $134.95 for 67 days= $182.18 for 90 daysSave 99%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy OU.S. shipping limited | Mysoline (Primidone)250 mg · brand · Filled in IndiaMade for sale in India.Product of India | $377for 200 tablets$1.89 per tablet | $14.95Pharmacy's estimate: 8–14 business days | $391.95 for 67 days= $529.13 for 90 daysSave 97%Worked out from a 67-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per tabletOnline pharmacy N | MYSOLINE 250MG TABLET 400 (BRAND FROM AUSTRALIA)250 mg · brand · Filled in AustraliaProduct of Australia | $200for 400 tablets$0.50 per tabletOver 3-month supply | $14.95Pharmacy's estimate: 4–6 weeks | $214.95 for 133 days= $145.09 for 90 daysSave 99%Worked out from a 133-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Mysoline from Canada?
90-day cost = 270 tablets at the usual dose of 3 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 12, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price of the same strength (250 mg); rows for other strengths show no saving. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
Members see pharmacy names, ratings, visit links and price-drop alerts.
Join to See PharmaciesAlready a member? Sign inMysoline price by strength
| Strength | Lowest brand90 days | Lowest generic abroad90 days, not FDA-approved | Price per tablet |
|---|---|---|---|
| Mysoline 50 mg | — | $445.43 | $1.60 generic |
| Mysoline 125 mg | — | $80.80 | $0.25 generic |
| Mysoline 250 mg | $170.22 | $97.62 | $0.63 brand · $0.31 generic |
Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per tablet is for that lowest pack, before shipping. Prices checked Nov 12, 2026.
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90-day prices from 9 licensed pharmacies abroad shipping to the U.S.: $80.80 to $911.18, any strength, shipping included.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Mysoline · Similar drugs · Uses · FAQ
Mysoline (primidone) tablets for epileptic seizures. FDA-approved generic primidone is sold in the U.S.
Mysoline cost at a glance
- U.S. list price: $7,523.36 for a bottle of 100 tablets of brand Mysoline 250 mg, about $75.23 a tablet. At 3 tablets a day, that's $20,313.07 for 90 days. The 50 mg lists at $2,186.21 for 100 (the maker's wholesale price before discounts; Texas DSHS).
- Generic Mysoline is sold in the U.S., for far less. The FDA has approved generic primidone tablets from many companies, rated equivalent to Mysoline (FDA Orange Book). In the 2026 filing, Lannett's and AdvaGen's list at $29.11 for 100 tablets of 250 mg and $15.96 for 100 of 50 mg (Texas DSHS).
- How we count: 3 tablets of 250 mg a day (270 for 90 days). The label's usual maintenance dose is 250 mg three or four times a day, reached step by step over about 10 days. If you take 4 a day, the cost is a third higher.
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
- From online pharmacies abroad: $170.22 to $239.22 for 90 days of brand Mysoline 250 mg, shipping included (checked Nov 12, 2026). The U.S. list price for 270 tablets is $20,313.07.
How much does Mysoline cost in the U.S.?
| If you have | What Mysoline costs | Source |
|---|---|---|
| No insurance (list price) | $7,523.36 for 100 tablets of brand Mysoline 250 mg and $2,186.21 for 100 tablets of 50 mg. Pharmacies may charge more. | Texas DSHS 2026 WAC report |
| No insurance (generic primidone) | FDA-approved generic primidone is sold in the U.S. The 2026 filing lists Lannett's at $29.11 for 100 tablets of 250 mg and $15.96 for 100 of 50 mg. Ask your pharmacist for the cash price. | Texas DSHS 2026 WAC report |
| Private or employer insurance | Your copay depends on your plan and whether it covers brand Mysoline or generic primidone, which the FDA rates as equivalent. Ask your plan or pharmacist. | FDA Orange Book |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Brand Mysoline 250 mg lists at $7,523.36 for a bottle of 100 tablets in the U.S., and the 50 mg at $2,186.21 (Texas DSHS). Generic primidone costs a tiny fraction of that: Lannett's 250 mg lists at $29.11 for 100 tablets in the same filing. These are list prices (the maker's wholesale price before discounts); what a pharmacy charges can differ.
Mysoline cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for brand Mysoline or generic primidone depends on your plan's drug list.
| Medicare Part D | What Mysoline costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Mysoline coupons and savings programs
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
eDrugSearch does not offer its own Mysoline coupons. eDrugSearch has no coupons of its own. If you have Medicare, these two programs can help with the cost of brand Mysoline or generic primidone:
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Mysoline?
Yes. Generic primidone tablets have been FDA-approved since before 1982. Today Amneal, Carnegie, Lannett, Oxford, Rubicon, TP ANDA Holdings, Watson and others sell generics rated equivalent to Mysoline.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 50 mg | Yes | Amneal, Carnegie, Lannett, Oxford, Rubicon, TP ANDA Holdings | — |
| 125 mg | Yes | Rubicon | Jun 28, 2022 |
| 250 mg | Yes | Amneal, Carnegie, Lannett, Oxford, Rubicon, TP ANDA Holdings, Watson | — |
Outside the U.S.: Online pharmacies abroad may also sell generic primidone made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: FDA Orange Book: primidone tablets. As of Nov 12, 2026.
Compare Mysoline with similar drugs
Other seizure medicines with price pages here. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Keppralevetiracetam | Seizure medicine (antiepileptic) | $36.94 for 90 days | See prices |
| Lamictallamotrigine | Anti-seizure medicine (also used for bipolar I disorder) | From $0.20 per tablet | See prices |
| Dilantinphenytoin | Seizure medicine (anticonvulsant) | From $0.13 per capsule | See prices |
| Tegretolcarbamazepine | Anticonvulsant (seizure medicine) | $40.89 for 90 days | See prices |
| Depakotedivalproex | Anti-seizure medicine and mood stabilizer (valproate) | From $0.45 per tablet | See prices |
| Topamaxtopiramate | Anti-seizure medicine also used to prevent migraine | $48.75 for 90 days | See prices |
Lowest price from licensed pharmacies shipping to the U.S., any strength: 90-day prices include shipping; prices per unit are before shipping. Only your doctor can decide whether another drug is right for you.
What is Mysoline used for?
Mysoline (primidone) is a seizure medicine (anticonvulsant). According to its FDA label (DailyMed), it is used:
- Alone or with other seizure medicines to control grand mal (tonic-clonic), psychomotor and focal epileptic seizures.
- For grand mal seizures that other seizure medicines haven't controlled.
Mysoline comes as scored 50 mg and 250 mg tablets in bottles of 100. The label starts with 100 to 125 mg at bedtime and raises the dose over about 10 days to a usual maintenance dose of 250 mg three or four times a day, with a top dose of 2,000 mg a day. Your prescriber decides which medicine is right for you.
Is it safe to order Mysoline from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Mysoline, compare the U.S. price of the FDA-approved generic primidone before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. Health Canada lists all brand Mysoline tablets as cancelled (Health Canada, checked 2026-11-12), so we don't show Canadian brand Mysoline packs.
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much does Mysoline cost without insurance?
The U.S. list price of brand Mysoline 250 mg is $7,523.36 for 100 tablets, or $20,313.07 for 90 days at 3 tablets a day. The 50 mg lists at $2,186.21 for 100. Online pharmacies abroad charged from $170.22 for 90 days of brand Mysoline 250 mg in our latest check (Nov 12, 2026). FDA-approved generic primidone is also sold in the U.S.
Is there a generic Mysoline?
Yes. Generic primidone tablets are FDA-approved and rated equivalent to Mysoline. Many companies make them in 50 mg and 250 mg. Ask your pharmacist whether a generic can fill your prescription.
How much does generic primidone cost?
In the 2026 drug price filing, Lannett's and AdvaGen's generic primidone list at $29.11 for 100 tablets of 250 mg and $15.96 for 100 of 50 mg. AvKare's 250 mg lists at $33.17. These are list prices; ask your pharmacist for the cash price.
Why is brand Mysoline so expensive?
We can't say why the maker sets its price. What we can show is the gap: brand Mysoline 250 mg lists at $7,523.36 for 100 tablets, while FDA-approved generic primidone 250 mg lists from $29.11 for 100 in the same 2026 filing.
How much does Mysoline cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help.
What strengths does Mysoline come in?
Brand Mysoline comes in 50 mg and 250 mg scored tablets, in bottles of 100. Generic primidone is also sold in 125 mg.
Sources
- MYSOLINE tablets U.S. prescribing information (DailyMed) (Bausch Health label version 11, effective 2026-09-10: seizure indications; titration to usual maintenance 250 mg three or four times daily, max 2,000 mg/day; 50 and 250 mg x100)
- Texas DSHS: 2026 annual WAC report (Mysoline x100: 50 mg (66490-0690-10) $2,186.21; 250 mg (66490-0691-10) $7,523.36. AvKare primidone x100: 250 mg $33.17, 50 mg $20.71; Actavis 250 mg x100 $36.18; Lannett x100 (ANDA 084903): 250 mg (00527-1231-01) $29.11, 50 mg (00527-1301-01) $15.96; AdvaGen (ANDA 214896) same prices)
- Drugs@FDA: Mysoline (NDA 009170) (Bausch (Valeant); approved before 1982; 50 and 250 mg RX)
- FDA Orange Book: primidone tablets (AB generics on the market from Amneal, Carnegie, Lannett, Oxford, Rubicon, TP ANDA Holdings, Watson (Lannett/Watson approved before 1982))
- Health Canada Drug Product Database: Mysoline (all Mysoline DINs cancelled post-market (last 2004-08-05); checked 2026-11-12)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.