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Lokelma Price (sodium zirconium cyclosilicate)

As of Nov 5, 2026, brand Lokelma 10 g costs from $2,474.95 for 90 days at licensed pharmacies abroad (ships from United Kingdom; packs made for other countries are not FDA-approved), vs. $2,662.11 at the U.S. list price.

U.S. list price
$2,662.11 for 90 days (90 packets)The maker's price for brand Lokelma before discounts · Source: AstraZeneca price disclosure
Lowest international online pharmacy price
$27.33 per packet$2,474.95 for 90 days (90 packets), shipping included · brand Lokelma 10 g, not FDA-approved · ships from United Kingdom
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Prices checked Nov 5, 2026 · Page updated November 11, 2026 · By the eDrugSearch team · How we check pharmacies and prices

Compare Lokelma prices from licensed pharmacies

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For comparison U.S. pharmacy list price: $2,662.11 for 90 days ($29.58 per packet), brand Lokelma 5 g or 10 g before insurance. The prices below are from licensed online pharmacies outside the U.S.

PharmacyMedicationPriceShipping & deliveryTotal (90 days)Buy
Online pharmacy ALokelma 5g Powder (UK/EU pack, ships from United Kingdom)5 g · brand · Filled in United KingdomMaker listed by pharmacy: Maker not shown by pharmacyMade for UK/EU$323.61per 30 packets · 3 packs = $970.83$10.79 per packetFee not publishedDelivery time not stated$970.83 for 90 days= $970.83 for 90 days+ shippingSave 64%incl. $0 shippingChecked Nov 7See pharmacy (members) Members see the pharmacy
Online pharmacy BLokelma 5g5 g · brand · Filled in United KingdomMaker listed by pharmacy: AstraZeneca$489per 30 packets · 3 packs = $1,467$16.30 per packet$9.95Pharmacy's estimate: 4–6 weeks$1,476.95 for 90 days= $1,476.95 for 90 daysSave 45%incl. $9.95 shippingChecked Nov 7See pharmacy (members) Members see the pharmacy
Online pharmacy BLokelma 5g5 g · brand · Filled in CanadaMaker listed by pharmacy: AstraZeneca$525per 30 packets · 3 packs = $1,575$17.50 per packet$9.95Pharmacy's estimate: 4–6 weeks$1,584.95 for 90 days= $1,584.95 for 90 daysSave 40%incl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy CLOKELMA 10G SACHET 30 (BRAND FROM UK)10 g · brand · Filled in United KingdomMaker listed by pharmacy: ASTRAZENECA$820per 30 packets · 3 packs = $2,460$27.33 per packet$14.95Pharmacy's estimate: 4–6 weeks$2,474.95 for 90 days= $2,474.95 for 90 daysSave 7%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy BLokelma 10g10 g · brand · Filled in CanadaMaker listed by pharmacy: AstraZeneca$270per 9 packets · 10 packs = $2,700$30.00 per packet$9.95Pharmacy's estimate: 4–6 weeks$2,709.95 for 90 days= $2,709.95 for 90 daysincl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy DLokelma10 g · brand · Filled in CanadaMaker listed by pharmacy: Astra-Zeneca Canada Inc.$2,851.99for 90 packets$31.69 per packet$9.95Pharmacy's estimate: 3–6 weeks$2,861.94 for 90 days= $2,861.94 for 90 daysincl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy BLokelma 10g10 g · brand · Filled in United KingdomMaker listed by pharmacy: AstraZeneca$330per 9 packets · 10 packs = $3,300$36.67 per packet$9.95Pharmacy's estimate: 4–6 weeks$3,309.95 for 90 days= $3,309.95 for 90 daysincl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy

Buying from a pharmacy outside the U.S.? Read Is it safe to order Lokelma from Canada?

90-day cost = 90 packets at the usual dose of 1 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 5, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price of the same strength (5 g or 10 g). The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.

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90-day prices from 3 licensed pharmacies shipping to the U.S.: $1,476.95 to $3,309.95, any strength, shipping included.

Jump to: Medicare · Maker savings · Generic Lokelma · Similar drugs · Uses · FAQ

Lokelma (sodium zirconium cyclosilicate) for high potassium, 5 g and 10 g packets. No generic is sold in the U.S. yet; compare brand prices and savings.

Lokelma price by strength

StrengthLowest brand90 daysPrice per packet
Lokelma 5 g$1,476.95$16.30
Lokelma 10 g$2,474.95$27.33

Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per packet is for that lowest pack, before shipping. Prices checked Nov 5, 2026.

Cheapest ways to get Lokelma 10 g

The cheapest ways we found to get brand Lokelma 10 g (prices checked Nov 5, 2026). The lowest 90-day cost is shaded green.

Way to buyCostDetails
Licensed online pharmacy abroad$2,474.95 for 90 daysBrand Lokelma 10 g, ships from United Kingdom, not FDA-approved (made for another country). Shipping included, checked Nov 5, 2026. See all prices
U.S. list price$2,662.11 for 90 daysBrand Lokelma before insurance. Pharmacies may charge more.
Medicare Part DDepends on your planYour plan’s drug list and coverage phase set your cost. Medicare costs

Costs abroad and at U.S. pharmacies are for one order closest to 90 days, shipping included, from the price table above. Programs set their own rules, so check the terms before you count on one.

How much does Lokelma cost without insurance?

Without insurance, Lokelma costs $887.37 for a 30-day supply at the U.S. list price, or about $2,662.11 for 90 days. Licensed pharmacies abroad charged from $2,474.95 for 90 days of brand Lokelma 10 g in our latest check (Nov 5, 2026), shipping included. Lokelma copay program, cash terms: AstraZeneca may pay up to the first $250 of each monthly prescription (up to 30 packets); you pay the rest. U.S. and Puerto Rico residents 18 and older. Not for anyone enrolled in Medicare Part D or Medicaid, and a cash purchase won't count toward a Medicare plan or its $2,100 yearly cap (AstraZeneca).

Lokelma cost with Medicare

In 2026, a Medicare drug plan (Part D) can charge a deductible of up to $615, and once you've spent $2,100 out of pocket on covered drugs, you pay nothing more for covered drugs that year ($2,400 in 2027) (Medicare.gov). What you pay for Lokelma depends on your plan's drug list and your coverage phase. If your income is limited, Extra Help lowers drug costs: in 2026 you pay no more than $5.10 for a generic and $12.65 for a brand-name drug, with income under $23,940 ($32,460 for a married couple) and resources under $18,090 ($36,100 for a couple) (CMS). The free Medicare Prescription Payment Plan spreads costs into monthly payments, but it doesn't lower the total.

Medicare Part DWhat Lokelma costsSource
Part D deductible (2026)Up to $615 a year, depending on your planMedicare.gov
Yearly out-of-pocket cap (2026)$2,100 for covered Part D drugs ($2,400 in 2027)Medicare.gov

Lokelma cost with insurance

With private or employer insurance, what you pay for Lokelma depends on your plan's drug list, deductible and copay. Your copay depends on your plan. The LOKELMA copay program may lower it to as little as $0 for up to 30 packets (maximum savings $350 per 30 packets), for up to 1 year (AstraZeneca).

Medicaid: Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office (Medicaid.gov).

Lokelma patient assistance program

AstraZeneca runs AZ&Me Prescription Savings Program. Who qualifies: U.S. residents treated by a U.S.-licensed prescriber who have no commercial (private or employer) insurance, with household income at or below 300% of the federal poverty level for most medicines ($47,880 for 1 person in the 48 states, effective January 26, 2026). People with Medicare must not be eligible for or enrolled in Extra Help. We couldn't confirm on the program's own pages that Lokelma is on its current list (checked 2026-10-29), so call 1-800-292-6363 to ask before you apply.

Is there a generic Lokelma?

No. Generic Lokelma is not sold in U.S. pharmacies yet. The FDA approved generic sodium zirconium cyclosilicate (5 g and 10 g packets) from Lupin on August 7, 2026, rated equivalent to Lokelma, but no generic is listed for sale in the FDA's drug listing directory as of October 2026.

StrengthU.S. genericMakersSince
5 gApproved, not soldLupin—
10 gApproved, not soldLupin—

Outside the U.S.: Online pharmacies abroad may sell sodium zirconium cyclosilicate made for other markets. Generic packs bought abroad are not FDA-approved, and the price table labels them that way.

Source: FDA Orange Book: sodium zirconium cyclosilicate. As of Oct 26, 2026.

Lokelma FAQ

How much is Lokelma without insurance?

The U.S. list price is $887.37 for 30 packets ($29.58 per packet), or about $2,662 for 90 days at one 10 g packet a day, per AstraZeneca's price disclosure. Licensed pharmacies abroad charged from $2,474.95 for 90 days of brand Lokelma 10 g in our latest check (Nov 5, 2026). For uninsured people, the LOKELMA copay program's cash terms say AstraZeneca may pay up to the first $250 of each monthly prescription.

How much does Lokelma cost with Medicare?

It depends on your Part D plan. In 2026, the deductible is at most $615 and out-of-pocket costs for covered drugs are capped at $2,100 a year ($2,400 in 2027). The LOKELMA copay program can't be used with Medicare, but people with limited income can apply for Extra Help.

Is there a generic Lokelma?

The FDA approved a generic from Lupin (sodium zirconium cyclosilicate, 5 g and 10 g packets) on August 7, 2026, but as of October 2026 no generic is listed for sale in the U.S. Brand Lokelma is the only version on the U.S. market.

Is there a Lokelma 10 mg?

No. Lokelma is measured in grams, not milligrams. It comes in 5 g and 10 g packets of powder that you mix with water.

Can I buy Lokelma from Canada?

Many Americans do, but U.S. law and customs rules apply, and you need a prescription. Lokelma is sold under the same name in Canada. See the section on buying from Canada above for the FDA's personal importation policy.

Is there a patient assistance program for Lokelma?

AstraZeneca runs AZ&Me Prescription Savings Program. Who qualifies: U.S. residents treated by a U.S.-licensed prescriber who have no commercial (private or employer) insurance, with household income at or below 300% of the federal poverty level for most medicines ($47,880 for 1 person in the 48 states, effective January 26, 2026). People with Medicare must not be eligible for or enrolled in Extra Help. We couldn't confirm on the program's own pages that Lokelma is on its current list (checked 2026-10-29), so call 1-800-292-6363 to ask before you apply.

Does Lokelma 5 g cost less than 10 g?

Not at list price. AstraZeneca lists both strengths at $29.58 per packet, or $887.37 for a box of 30 packets. Your prescriber sets the dose, which can range from 5 g every other day to 15 g a day for ongoing treatment, according to the label.

What is Lokelma used for?

Lokelma treats hyperkalemia, which means too much potassium in the blood, in adults. Its FDA label says it should not be used as an emergency treatment for life-threatening hyperkalemia because it takes time to work.

Savings programs from the maker

eDrugSearch does not offer its own Lokelma coupons. eDrugSearch has no coupons of its own. These are the programs we could verify:

  • LOKELMA Savings Card: for people with commercial insurance that doesn't cover the full cost: you may pay as little as $0 for up to a 30-packet supply, with a maximum savings of $350 per 30 packets, for up to 1 year. People with no insurance may use the card's cash terms instead (AstraZeneca may pay up to the first $250 of each monthly prescription). U.S. and Puerto Rico residents 18 and older. Not for anyone enrolled in Medicare Part D, Medicaid, Medigap, VA, Department of Defense programs or TRICARE, even if they choose to pay cash, and it won't count toward a Medicare plan's deductible or the $2,100 yearly out-of-pocket cap. With private insurance, ask your plan whether a cash purchase counts toward your deductible. Call 1-844-565-3562. (Lokelma.com)
  • Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
  • Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)

Compare Lokelma with similar drugs

Other medicines often used by people with chronic kidney disease or heart failure. They treat different conditions than Lokelma. Prices are for each drug's lowest-priced strength.

DrugTypeLowest price we foundLink
KerendiafinerenoneKidney and heart medicine (nonsteroidal mineralocorticoid receptor antagonist)$249.05 for 90 daysSee prices
FarxigadapagliflozinDiabetes, heart and kidney medicine (SGLT2 inhibitor)$53.09 for 90 daysSee prices
JardianceempagliflozinDiabetes, heart and kidney medicine (SGLT2 inhibitor)$77.05 for 90 daysSee prices

Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.

What is Lokelma used for?

Lokelma (sodium zirconium cyclosilicate) is a potassium binder. According to its FDA label (DailyMed), it is used:

  • To treat hyperkalemia (high potassium in the blood) in adults.

Lokelma comes as 5 g and 10 g packets of powder that are mixed with water and taken by mouth. The label says it should not be used as an emergency treatment for life-threatening hyperkalemia because it takes time to work, and that each 5 g contains about 400 mg of sodium. Other medicines taken by mouth are generally taken at least 2 hours before or after Lokelma. The label has no boxed warning. Your prescriber decides which medicine is right for you.

Is it safe to order Lokelma from Canada?

Many Americans do, but U.S. law and customs rules apply. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress declared in FD&C Act 804(j)(1), 21 U.S.C. 384(j)(1), that enforcement against individuals should focus on imports posing a significant threat to public health. You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, the U.K. and Europe, Lokelma is sold under the same name, where the packets are often called sachets.

Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.

Sources

eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.