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Jakafi Price (ruxolitinib)

As of Nov 11, 2026, brand Jakafi 10 mg costs from $19,074.59 for 90 days at licensed pharmacies abroad (ships from Canada; packs made for other countries are not FDA-approved), vs. $54,570 at the U.S. list price.

U.S. list price
$54,570 for 90 days (180 tablets)The maker's price for brand Jakafi before discounts · Source: Incyte
Lowest international online pharmacy price
$105.91 per tablet$19,074.59 for 90 days (180 tablets), shipping included · brand Jakafi 10 mg, not FDA-approved · ships from Canada
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Prices checked Nov 11, 2026 · Page updated November 11, 2026 · By the eDrugSearch team · How we check pharmacies and prices

Name check: Jakafi XR (once-daily 11 to 55 mg tablets) and Opzelura cream also contain ruxolitinib, but they are separate products and their prices are not mixed in here.

Compare Jakafi prices from licensed pharmacies

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For comparison U.S. pharmacy list price: $54,570 for 90 days ($303.17 per tablet), brand Jakafi 5 mg, 10 mg, 15 mg, 20 mg or 25 mg before insurance. The prices below are from licensed online pharmacies outside the U.S.

PharmacyMedicationPriceShipping & deliveryTotal (90 days)Buy
Online pharmacy AJAKAFI 5MG TABLET 56 (JAKAVI BRAND FROM AUSTRALIA)5 mg · brand · Filled in AustraliaMaker listed by pharmacy: NOVARTIS$3,000per 56 tablets · 3 packs = $9,000$53.57 per tablet$14.95Pharmacy's estimate: 4–6 weeks$9,014.95 for 84 days= $9,658.88 for 90 daysSave 82%Worked out from an 84-day orderChecked Nov 7See pharmacy (members) Members see the pharmacy
Online pharmacy BJAKAFI (EU pack, ships from Australia)5 mg · brand · Filled in AustraliaProduct of EU$3,969.72per 56 tablets · 3 packs = $11,909.16$70.89 per tabletFreeDelivery time not stated$11,909.16 for 84 days= $12,759.81 for 90 daysSave 77%Worked out from an 84-day orderChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy CJakavi 5mg Tablet5 mg · brand · Filled in AustraliaMaker listed by pharmacy: Novartis$12,459.84for 168 tablets$74.17 per tabletFreePharmacy's estimate: 2–3 weeks$12,459.84 for 84 days= $13,349.83 for 90 daysSave 76%Worked out from an 84-day orderChecked Nov 7See pharmacy (members) Members see the pharmacy
Online pharmacy AJAKAFI 15MG TABLET 56 (JAKAVI BRAND FROM NEW ZEALAND)15 mg · brand · Filled in New ZealandMaker listed by pharmacy: NOVARTIS$4,525per 56 tablets · 3 packs = $13,575$80.80 per tablet$14.95Pharmacy's estimate: 4–6 weeks$13,589.95 for 84 days= $14,560.66 for 90 daysSave 73%Worked out from an 84-day orderChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy DJakavi 15mg Tablet15 mg · brand · Filled in CanadaMaker listed by pharmacy: Novartis$5,830per 56 tablets · 3 packs = $17,490$104.11 per tablet$9.95Pharmacy's estimate: 4–6 weeks$17,499.95 for 84 days= $18,749.95 for 90 daysSave 66%Worked out from an 84-day orderChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy DJakavi 5mg Tablet5 mg · brand · Filled in CanadaMaker listed by pharmacy: Novartis$5,931per 56 tablets · 3 packs = $17,793$105.91 per tablet$9.95Pharmacy's estimate: 4–6 weeks$17,802.95 for 84 days= $19,074.59 for 90 daysSave 65%Worked out from an 84-day orderChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy DJakavi 10mg Tablet10 mg · brand · Filled in CanadaMaker listed by pharmacy: Novartis$5,931per 56 tablets · 3 packs = $17,793$105.91 per tablet$9.95Pharmacy's estimate: 4–6 weeks$17,802.95 for 84 days= $19,074.59 for 90 daysSave 65%Worked out from an 84-day orderChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy AJAKAFI 20MG TABLET 56 (JAKAVI BRAND FROM AUSTRALIA)20 mg · brand · Filled in AustraliaMaker listed by pharmacy: NOVARTIS$5,950per 56 tablets · 3 packs = $17,850$106.25 per tablet$14.95Pharmacy's estimate: 4–6 weeks$17,864.95 for 84 days= $19,141.02 for 90 daysSave 65%Worked out from an 84-day orderChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy CJakavi 5mg Tablet5 mg · brand · Filled in CanadaMaker listed by pharmacy: Novartis$6,001.29per 56 tablets · 3 packs = $18,003.87$107.17 per tabletFreePharmacy's estimate: 2–3 weeks$18,003.87 for 84 days= $19,289.86 for 90 daysSave 65%Worked out from an 84-day orderChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy CJakavi 20mg Tablet20 mg · brand · Filled in AustraliaMaker listed by pharmacy: Novartis$6,009.99per 56 tablets · 3 packs = $18,029.97$107.32 per tabletFreePharmacy's estimate: 2–3 weeks$18,029.97 for 84 days= $19,317.83 for 90 daysSave 65%Worked out from an 84-day orderChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy DJakavi 20mg Tablet20 mg · brand · Filled in CanadaMaker listed by pharmacy: Novartis$6,030per 56 tablets · 3 packs = $18,090$107.68 per tablet$9.95Pharmacy's estimate: 4–6 weeks$18,099.95 for 84 days= $19,392.80 for 90 daysSave 64%Worked out from an 84-day orderChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy BJAKAFI15 mg · brand · Filled in New ZealandProduct of New Zealand$6,045.27per 56 tablets · 3 packs = $18,135.81$107.95 per tabletFreeDelivery time not stated$18,135.81 for 84 days= $19,431.23 for 90 daysSave 64%Worked out from an 84-day orderChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy CJakavi 10mg Tablet10 mg · brand · Filled in CanadaMaker listed by pharmacy: Novartis$18,615.45for 168 tablets$110.81 per tabletFreePharmacy's estimate: 2–3 weeks$18,615.45 for 84 days= $19,945.13 for 90 daysSave 63%Worked out from an 84-day orderChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy CJakavi 15mg Tablet15 mg · brand · Filled in CanadaMaker listed by pharmacy: Novartis$19,261.21for 168 tablets$114.65 per tabletFreePharmacy's estimate: 2–3 weeks$19,261.21 for 84 days= $20,637.01 for 90 daysSave 62%Worked out from an 84-day orderChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy CJakavi 20mg Tablet20 mg · brand · Filled in CanadaMaker listed by pharmacy: Novartis$19,912.81for 168 tablets$118.53 per tabletFreePharmacy's estimate: 2–3 weeks$19,912.81 for 84 days= $21,335.15 for 90 daysSave 61%Worked out from an 84-day orderChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy BJAKAFI (EU pack, ships from Australia)15 mg · brand · Filled in AustraliaProduct of EU$7,894.51per 56 tablets · 3 packs = $23,683.53$140.97 per tabletFreeDelivery time not stated$23,683.53 for 84 days= $25,375.21 for 90 daysSave 53%Worked out from an 84-day orderChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy BJAKAFI (EU pack, ships from Australia)20 mg · brand · Filled in AustraliaProduct of EU$7,894.51per 56 tablets · 3 packs = $23,683.53$140.97 per tabletFreeDelivery time not stated$23,683.53 for 84 days= $25,375.21 for 90 daysSave 53%Worked out from an 84-day orderChecked Nov 11See pharmacy (members) Members see the pharmacy

Buying from a pharmacy outside the U.S.? Read Is it safe to order Jakafi from Canada?

90-day cost = 180 tablets at the usual dose of 2 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price of the same strength (5 mg, 10 mg, 15 mg, 20 mg or 25 mg). The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout.

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90-day prices from 4 licensed pharmacies shipping to the U.S.: $9,658.88 to $25,375.21, any strength, shipping included.

Jump to: Medicare · Maker savings · Generic Jakafi · Uses · FAQ

Jakafi (ruxolitinib) tablets, 5 to 25 mg, for myelofibrosis, polycythemia vera and GVHD. No U.S. generic is sold, so compare brand prices and help programs.

Jakafi price by strength

StrengthLowest brand90 daysPrice per tablet
Jakafi 5 mg$9,658.88$53.57
Jakafi 10 mg$19,074.59$105.91
Jakafi 15 mg$14,560.66$80.80
Jakafi 20 mg$19,141.02$106.25

Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per tablet is for that lowest pack, before shipping. Prices checked Nov 11, 2026.

Cheapest ways to get Jakafi 10 mg

The cheapest ways we found to get brand Jakafi 10 mg (prices checked Nov 11, 2026). The lowest 90-day cost is shaded green.

Way to buyCostDetails
Licensed online pharmacy abroad$19,074.59 for 90 daysBrand Jakafi 10 mg, ships from Canada, not FDA-approved (made for another country). Shipping included, checked Nov 11, 2026. See all prices
U.S. list price$54,570 for 90 daysBrand Jakafi before insurance. Pharmacies may charge more.
Maker’s patient assistance programMay be free if you qualifyIncyteCARES Patient Assistance Program, checked Oct 29, 2026. Who qualifies
Medicare Part DDepends on your planYour plan’s drug list and coverage phase set your cost. Medicare costs

Costs abroad and at U.S. pharmacies are for one order closest to 90 days, shipping included, from the price table above. Programs set their own rules, so check the terms before you count on one.

How much does Jakafi cost without insurance?

Without insurance, Jakafi costs $18,190 for a 30-day supply at the U.S. list price, or about $54,570 for 90 days. Licensed pharmacies abroad charged from $19,074.59 for 90 days of brand Jakafi 10 mg in our latest check (Nov 11, 2026), shipping included. Incytecares free medicine: Free Jakafi for eligible patients who are uninsured or underinsured. Call IncyteCARES at 1-855-452-5234 (Incyte).

Jakafi cost with Medicare

In 2026, a Medicare drug plan (Part D) can charge a deductible of up to $615, and once you've spent $2,100 out of pocket on covered drugs, you pay nothing more for covered drugs that year ($2,400 in 2027) (Medicare.gov). What you pay for Jakafi depends on your plan's drug list and your coverage phase. If your income is limited, Extra Help lowers drug costs: in 2026 you pay no more than $5.10 for a generic and $12.65 for a brand-name drug, with income under $23,940 ($32,460 for a married couple) and resources under $18,090 ($36,100 for a couple) (CMS). The free Medicare Prescription Payment Plan spreads costs into monthly payments, but it doesn't lower the total.

Medicare Part DWhat Jakafi costsSource
Part D deductibleNo Medicare drug plan may have a deductible above $615 in 2026. Some plans have none.Medicare.gov
Yearly out-of-pocket capOnce your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026 ($2,400 in 2027), you pay nothing more for covered drugs that year.Medicare.gov

Jakafi cost with insurance

With private or employer insurance, what you pay for Jakafi depends on your plan's drug list, deductible and copay. As little as $0 a month with the IncyteCARES copay program, subject to an annual benefit maximum. Your copay otherwise depends on your plan (Incyte).

Medicaid: Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office (Medicaid.gov).

Jakafi patient assistance program

Yes. Jakafi is offered through IncyteCARES Patient Assistance Program, which can give the medicine at no cost to people who qualify. Who qualifies: Patients who are uninsured or underinsured for Jakafi. Terms apply and can change. How to apply: For Jakafi, call IncyteCARES at 1-855-452-5234 or ask your prescriber to enroll you. For Opzelura, start at incytecares.com (Opzelura support page). (Checked 2026-10-29.)

Is there a generic Jakafi?

No. No generic Jakafi is FDA-approved or sold in the U.S. The FDA Orange Book lists only Incyte's ruxolitinib products: Jakafi tablets, Jakafi XR extended-release tablets and Opzelura cream.

StrengthU.S. genericMakersSince
5 mgNo—
10 mgNo—
15 mgNo—
20 mgNo—
25 mgNo—

Outside the U.S.: Online pharmacies abroad may sell generic ruxolitinib made for other markets. Those packs are not FDA-approved, and the price table labels them that way.

Source: FDA Orange Book: ruxolitinib products. As of Oct 26, 2026.

Jakafi FAQ

How much does Jakafi cost without insurance?

Incyte lists Jakafi at $18,190 per bottle of 60 tablets, any strength, or about $54,570 for 90 days at two tablets a day; pharmacies may charge more. Licensed pharmacies abroad charged from $19,074.59 for 90 days of brand Jakafi 10 mg (Jakavi) in our latest check (Nov 11, 2026). Incyte says IncyteCARES offers free Jakafi to eligible patients who are uninsured or underinsured.

Does Medicare pay for Jakafi?

Coverage depends on your Part D plan, so check its drug list. In 2026, your out-of-pocket costs for covered Part D drugs are capped at $2,100 a year ($2,400 in 2027), after a deductible of up to $615. The IncyteCARES copay program can't be used with Medicare, but people with limited income can apply for Extra Help, and the Medicare Prescription Payment Plan can spread costs into monthly payments.

Is there a generic Jakafi?

No. The FDA Orange Book lists no approved generic of Jakafi, so none is sold in U.S. pharmacies. The generic name for Jakafi is ruxolitinib. Generic ruxolitinib sold abroad is not FDA-approved, and the price table labels it that way.

Where can I fill a Jakafi prescription?

IncyteCARES can arrange for an approved specialty pharmacy to fill your Jakafi prescription and deliver it to your home or your doctor's office. If your insurance coverage is delayed, Incyte says eligible patients can get a free short-term supply. IncyteCARES can also share information about independent organizations that may help with costs.

Is there a patient assistance program for Jakafi?

Yes. Jakafi is offered through IncyteCARES Patient Assistance Program, which can give the medicine at no cost to people who qualify. Who qualifies: Patients who are uninsured or underinsured for Jakafi. Terms apply and can change. How to apply: For Jakafi, call IncyteCARES at 1-855-452-5234 or ask your prescriber to enroll you. For Opzelura, start at incytecares.com (Opzelura support page). (Checked 2026-10-29.)

How much does Jakafi cost per month?

At the usual twice-daily dose, one 60-tablet bottle lasts 30 days, and Incyte's list price is $18,190 per bottle for every strength. What you pay depends on your coverage: eligible patients with commercial insurance may pay as little as $0 a month with the IncyteCARES copay program, and Medicare Part D out-of-pocket costs are capped at $2,100 in 2026 ($2,400 in 2027).

Is Jakavi the same as Jakafi?

Jakavi is the brand name Novartis uses for ruxolitinib outside the U.S., including Canada, the U.K. and Europe. Incyte sells it in the U.S. as Jakafi. In Canada, Jakavi comes as 5, 10, 15 and 20 mg tablets in packs of 56; the U.S. also has a 25 mg Jakafi tablet.

Savings programs from the maker

How do you pay?

We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.

eDrugSearch does not offer its own Jakafi coupons. Incyte's patient support program for Jakafi is IncyteCARES (1-855-452-5234). Each program below lists who it is for.

  • IncyteCARES copay program: for people with commercial prescription drug coverage. Eligible patients may pay as little as $0 a month, subject to an annual benefit maximum. Not for uninsured or cash-paying patients, or for Medicare Part D, Medicare Advantage, Medicaid, TRICARE or state assistance programs. Copay maximizer or accumulator programs may reduce its value. Call 1-855-452-5234. (IncyteCARES for Jakafi)
  • IncyteCARES Patient Assistance Program (free medicine): Incyte may provide Jakafi at no cost to eligible patients who are uninsured or underinsured, including people with Medicare Part D who can't afford it. Terms and conditions apply and may change; contact IncyteCARES to check eligibility. (IncyteCARES for Jakafi)
  • Medicare Extra Help: if you have Medicare and limited income, Extra Help may lower your Jakafi copay to $0 to $12.65 per prescription in 2026. (Social Security)
  • Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)

What is Jakafi used for?

Jakafi (ruxolitinib) is a kinase inhibitor, also called a JAK inhibitor. According to its FDA label (prescribing information), it is used to treat:

  • Intermediate- or high-risk myelofibrosis in adults, including primary myelofibrosis and myelofibrosis that follows polycythemia vera or essential thrombocythemia.
  • Polycythemia vera in adults who did not respond well enough to, or could not tolerate, hydroxyurea.
  • Acute graft-versus-host disease (GVHD) that did not respond to steroids, in adults and children 12 years and older.
  • Chronic GVHD after one or two other systemic treatments did not work, in adults and children 12 years and older.

Jakafi comes as 5, 10, 15, 20 and 25 mg tablets in bottles of 60 and is usually taken twice a day. It has no boxed warning. The label warns about low blood counts, serious infections, symptoms coming back after treatment is interrupted or stopped, non-melanoma skin cancer, higher cholesterol, heart attack and stroke, blood clots and new cancers. Your prescriber decides which medicine is right for you.

Is it safe to order Jakafi from Canada?

Many Americans do, but U.S. law and customs rules apply. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress declared in FD&C Act 804(j)(1), 21 U.S.C. 384(j)(1), that enforcement against individuals should focus on imports posing a significant threat to public health. You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, ruxolitinib is sold as Jakavi by Novartis as 5, 10, 15 and 20 mg tablets.

Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.