Generic Advair Diskus (fluticasone propionate and salmeterol) Price

Fluticasone and Salmeterol price by strength

Fluticasone and Salmeterol names

- Brand name: Advair Diskus (GSK)
- Generic name: fluticasone propionate and salmeterol
- Names in Canada: Advair, plus generics such as Pms-Fluticasone Propionate/Salmeterol Dpi (Health Canada Drug Product Database, marketed products, checked Oct 29, 2026)
- Other names: Wixela Inhub (generic, Mylan); Seretide Accuhaler (brand name in the U.K. and Europe)

Fluticasone propionate and salmeterol packs made for other countries are not FDA-approved.

Fluticasone and Salmeterol FAQ

Brand vs. generic: cost for 90 days

Lowest in this comparison: Generic fluticasone propionate and salmeterol 250/50 mcg, U.S. pharmacy cash price.

90 days = 3 inhalers of 250/50 mcg. Generic sold abroad is not FDA-approved and is not in this box. Your price with insurance or Medicare depends on your plan.

See brand Advair Diskus prices

Fluticasone and Salmeterol cost with Medicare in 2026

Each Part D plan has its own list of covered drugs and copays, so what you pay for fluticasone and salmeterol depends on your plan (Medicare Plan Finder). In 2026, Part D plans can have a yearly deductible of up to $615, and your out-of-pocket costs for covered drugs are capped at $2,100 a year ($2,400 in 2027) (Medicare.gov). GSK's $35 co-pay support is for brand Advair Diskus and can't be used with Medicare.

Savings programs from the maker

eDrugSearch does not offer its own Fluticasone and Salmeterol coupons. GSK's $35 monthly inhaler cap is for brand Advair Diskus (see the brand page). These programs can lower what you pay for generic fluticasone and salmeterol:

• Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
• Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
• Costco Pharmacy member prices: Costco publishes member prices for many prescriptions, for people with a Costco membership. Non-members can also use Costco pharmacies and pay the regular cash price. Member prices can't be used with insurance, Medicare or Medicaid claims. (Costco Pharmacy)
• Amazon Pharmacy Prime and RxPass: Amazon Pharmacy offers Prime members discounts on many prescriptions, and RxPass, for Prime members, covers a set list of generics for a flat monthly fee. Prime is not required to use Amazon Pharmacy. Prime savings have limits for people with Medicare, Medicaid or Tricare, and RxPass is not open to people with Medicaid or CHIP. (Amazon Pharmacy)
• Discount cards: Discount cards (for example GoodRx or SingleCare) may lower the price at local pharmacies; prices vary by pharmacy and ZIP code.

When people choose brand Advair Diskus

Some people get brand Advair Diskus instead of generic fluticasone propionate and salmeterol. Common reasons:

• A prescription marked “dispense as written” (or “brand medically necessary”) tells the pharmacy to fill brand Advair Diskus, not a generic. State laws set the rules for generic substitution.
• GSK says eligible patients pay no more than $35 a month for its asthma and COPD inhalers, including brand Advair Diskus (GSK). Terms apply, and it can't be used with Medicare or Medicaid.
• Some insurance and Medicare drug plans cover the brand and the generic at different copays, or cover only one of them. Your plan's drug list shows which.

Your prescriber decides which medicine is right for you.

Compare prices for your other medicines

• Advair Diskus prices from $88.95 for 90 days
• Breo Ellipta prices from $135.95 for 90 days
• Symbicort prices from $75.61 for 90 days

Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength.

What is Fluticasone and Salmeterol used for?

Fluticasone propionate and salmeterol combines an inhaled corticosteroid with a long-acting beta2-agonist, the same medicines as in Advair Diskus. The FDA label for Advair Diskus (DailyMed) lists these uses:

• Twice-daily treatment of asthma in people 4 years and older.
• Maintenance treatment of airflow obstruction in chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema, and to reduce COPD flare-ups in people who have had them (250/50 mcg strength).

It is not a rescue inhaler and is not used for sudden breathing problems. It comes in three strengths: 100/50, 250/50 and 500/50 mcg. The FDA label lists 250/50 mcg as the only COPD dose and 100/50 mcg for children 4 to 11 with asthma. Each inhaler holds 60 doses. Check the label that comes with your medicine. Your prescriber decides which medicine is right for you.