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Cresemba Price and Savings
- U.S. list price
- $21,459.60 for 90 days (180 capsules)The maker's price for brand Cresemba before discounts · Source: Texas DSHS 2026 WAC report
- Lowest international online pharmacy price
- $97.46 per capsule$17,557.07 for 90 days (180 capsules), shipping included · brand Cresemba 100 mg, not FDA-approved · ships from Canada
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Quick answerAs of Nov 12, 2026, brand Cresemba 100 mg costs from $17,557.07 for 90 days at online pharmacies abroad we compared, vs. $21,459.60 at the U.S. list price ($1,669.08 per 14 capsules). No generic is sold in the U.S.
Name check: Each U.S. Cresemba 186 mg capsule holds 100 mg of isavuconazole, the strength printed on packs abroad. The 74.5 mg capsules and the injection aren't priced here.
Compare Cresemba prices from licensed online pharmacies
For comparison U.S. pharmacy list price: $21,459.60 for 90 days ($119.22 per capsule), brand Cresemba before insurance. The prices below are from licensed online pharmacies outside the U.S.
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per capsuleOnline pharmacy A | Brand Cresemba 100mg100 mg · brand · Filled in CanadaMaker listed by pharmacy: Avr | $1,364.40per 14 capsules · 13 packs = $17,737.20$97.46 per capsule | $14.95Pharmacy's estimate: 4–6 weeks | $17,752.15 for 91 days= $17,557.07 for 90 daysSave 18%Worked out from a 91-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleOnline pharmacy B | Brand Cresemba 100mg100 mg · brand · Filled in CanadaMaker listed by pharmacy: Avr | $1,495.79per 14 capsules · 13 packs = $19,445.27$106.84 per capsule | $14.95Pharmacy's estimate: 4–6 weeks | $19,460.22 for 91 days= $19,246.37 for 90 daysSave 10%Worked out from a 91-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
| Lowest per capsuleLicensed Canadian pharmacy C | Cresemba100 mg · brand · Filled in CanadaMaker listed by pharmacy: AVIR PHARMA INC. | $1,500.46per 14 capsules · 13 packs = $19,505.98$107.18 per capsule | $9.95Pharmacy's estimate: 3–6 weeks | $19,515.93 for 91 days= $19,301.47 for 90 daysSave 10%Worked out from a 91-day orderChecked Nov 12 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Cresemba from Canada?
90-day cost = 180 capsules at the usual dose of 2 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 12, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout.
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Join to See PharmaciesAlready a member? Sign inCresemba price by strength
| Strength | Lowest brand90 days | Price per capsule |
|---|---|---|
| Cresemba 100 mg | $17,557.07 | $97.46 |
Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per capsule is for that lowest pack, before shipping. Prices checked Nov 12, 2026.
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90-day prices from 3 licensed pharmacies shipping to the U.S.: $17,557.07 to $19,301.47, any strength, shipping included.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Cresemba · Similar drugs · Uses · FAQ
Cresemba (isavuconazonium sulfate) capsules treat invasive aspergillosis and mucormycosis, serious fungal infections. No U.S. generic is sold.
Cresemba cost at a glance
- U.S. list price: $1,669.08 for a carton of 14 Cresemba 186 mg capsules, about $119.22 a capsule. At the label's 2 capsules a day, that's $7,153.20 for 30 days or $21,459.60 for 90 days. This is the maker's wholesale price before discounts (Texas DSHS).
- No U.S. generic. Drugs@FDA lists Astellas's Cresemba as the only isavuconazonium sulfate product, with no generic approved (Drugs@FDA).
- With private insurance: the Cresemba Patient Savings Program may lower your cost to as little as $25 per prescription, up to $4,000 a year. It's for commercial insurance only, not Medicare, Medicaid or cash payers (Cresemba).
- How we count: 2 capsules a day, the adult maintenance dose. Treatment starts with 2 capsules every 8 hours for 2 days (12 capsules), then 2 capsules once a day. Each 186 mg capsule contains 100 mg of isavuconazole.
- From online pharmacies abroad: $17,557.07 to $19,301.47 for 90 days of brand Cresemba 100 mg, shipping included (checked Nov 12, 2026). The U.S. list price for 90 days is $21,459.60.
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
How much does Cresemba cost in the U.S.?
| If you have | What Cresemba costs | Source |
|---|---|---|
| No insurance (list price) | $1,669.08 for 14 capsules (7 days at 2 a day), or $7,153.20 for 30 days. Pharmacies may charge more. | Texas DSHS 2026 WAC report |
| Private or employer insurance | Your copay depends on your plan. With the Cresemba Patient Savings Program, eligible people may pay as little as $25 per prescription, up to $4,000 a year. | Cresemba |
| Medicare Part D | Your cost depends on your plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100. Astellas's support team (1-800-477-6472) can help check Medicare benefits. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Cresemba lists at $1,669.08 for a carton of 14 capsules in the U.S., about $119.22 a capsule (Texas DSHS). At 2 capsules a day, that carton lasts 7 days. That's the maker's wholesale price before discounts; what a pharmacy charges can differ. There's no FDA-approved generic.
Cresemba cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Cresemba depends on your plan's drug list. The Cresemba savings program can't be used with Medicare.
| Medicare Part D | What Cresemba costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Cresemba coupons and savings programs
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
eDrugSearch does not offer its own Cresemba coupons. eDrugSearch has no coupons of its own. These programs can help:
- Cresemba Patient Savings Program (Astellas): for people with commercial prescription insurance. You may pay as little as $25 per prescription, up to $4,000 a calendar year. Not for Medicare, Medicaid, Medigap, VA, DoD, TRICARE or other government programs, or for cash payers. (Program terms)
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Cresemba?
No. No generic Cresemba is sold in the U.S. Drugs@FDA lists Astellas's Cresemba capsules and injection (approved March 6, 2015) as the only isavuconazonium sulfate products.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 100 mg | No | — |
Outside the U.S.: Online pharmacies abroad may sell isavuconazole made for other markets. Packs made for other countries are not FDA-approved.
Source: Drugs@FDA: Cresemba (NDA 207500). As of Nov 12, 2026.
Compare Cresemba with similar drugs
Other azole antifungal pills with price pages here, including Sporanox (itraconazole) and Vfend (voriconazole). They treat different fungal infections. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Sporanoxitraconazole | Antifungal medicine (azole) | $148.43 for 90 days | See prices |
| Vfendvoriconazole | Antifungal (azole) | $467.45 for 90 days | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Cresemba used for?
Cresemba (isavuconazonium sulfate) is an azole antifungal. According to its FDA label (DailyMed), Cresemba capsules are used to treat, in adults and in children 6 and older who weigh at least 16 kg (35 lb):
- Invasive aspergillosis, a serious mold infection, usually of the lungs.
- Invasive mucormycosis, a rare but serious fungal infection.
For adults, the label dose is 2 capsules of 186 mg (372 mg) every 8 hours for 6 doses (48 hours), then 2 capsules once a day, with or without food. Children's doses use the 74.5 mg capsules and are set by weight. Your prescriber decides which medicine is right for you.
Is it safe to order Cresemba from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Cresemba, talk with your care team first, since these infections are serious and missed doses matter before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, Cresemba 100 mg and 40 mg capsules are sold under the same name by Avir Pharma and listed as marketed (Health Canada, checked 2026-11-12).
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much does Cresemba cost without insurance?
The U.S. list price is $1,669.08 for 14 capsules, about $119.22 each, in the maker's 2026 price filing. At 2 capsules a day, that's $7,153.20 for 30 days. Online pharmacies abroad charged from $17,557.07 for 90 days of brand Cresemba in our latest check (Nov 12, 2026), shipping included.
Is there a generic Cresemba?
No. Drugs@FDA lists no generic isavuconazonium sulfate, so brand Cresemba is the only version sold in the U.S.
Is Cresemba 186 mg the same as 100 mg?
Yes. Each U.S. capsule holds 186 mg of isavuconazonium sulfate, which equals 100 mg of isavuconazole. Packs sold in Canada and Europe show the 100 mg figure.
Is there a Cresemba copay card?
Yes, for people with commercial insurance. The Cresemba Patient Savings Program may lower your cost to as little as $25 per prescription, up to $4,000 a year. It can't be used with Medicare, Medicaid or other government plans, or by cash payers.
How much does Cresemba cost with Medicare?
It depends on your Part D plan's drug list. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help.
Sources
- CRESEMBA U.S. prescribing information (DailyMed) (Astellas label version 21, effective 2025-04-25: invasive aspergillosis and mucormycosis; adult loading 2 capsules q8h x6 doses then 2 capsules daily; 186 mg capsule = 100 mg isavuconazole; 14-count carton (NDC 0469-0520-02))
- Texas DSHS: 2026 annual WAC report (Cresemba 186 mg 0469-0520-02 (14 capsules) $1,669.08; 74.5 mg 0469-2860-35 (35) $1,672.59)
- Drugs@FDA: Cresemba (NDA 207500) (capsules approved March 6, 2015; no generic applications, checked 2026-11-12)
- Cresemba: access and support (commercial only; excludes government programs and cash payers; $4,000 calendar-year limit; Medicare help 1-800-477-6472; checked 2026-11-12)
- Cresemba Patient Savings Program (as little as $25 per prescription, up to $4,000 per calendar year)
- Health Canada Drug Product Database: Cresemba (100 mg capsule DIN 02483971, 40 mg DIN 02553279, Avir Pharma, Marketed; checked 2026-11-12)
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.