More people everyday are prescribed serotonin norepinephrine reuptake inhibitors aka SNRIs, which are a class of antidepressant used to treat depression. There are four main SNRIs: enlafaxine (Effexor), duloxetine (Cymbalta), milnacipran (Savella), and desvenlafaxine (Pristiq).
Today we are going to focus on two of the most commonly used of the four, Cymbalta and Effexor. Lets take a look at some of the similarities and differences between the two drugs, so that you can make a more informed decision when choosing between the two.
Effexor is the first and most commonly used SNRI while Cymbalta was most recently released on the market. It was approved by the FDA in August of 2004.
Both drugs work by preventing serotonin and noradrenaline from being reabsorbed back into the nerve cells in the brain. Effexor has been approved to treat, major depressive disorder, generalized anxiety disorder,
social anxiety disorder, and panic disorder while Cymbalta has been approved to treat major depressive disorder, diabetic peripheral neuropathic pain, generalized anxiety disorder, and fibromyalgia.
When treating depression, both drugs are similarly affective. In a randomized, double-blind study which compared Cymbalta 60 mg/day and Effexor XR 150 mg/day both Cymbalta and Effexor XR demonstrated substantial antidepressant efficacy and received a HAMD 17 total score. Both drugs are also affective at treating generalized anxiety disorder.
Effexor has also been proven affective at treating several “off label” uses as well. Many doctors are prescribing it for the treatment of diabetic neuropathy and migraine prophylaxis. Cymbalta has been recently prescribed “off label” to treat bipolar depression and new studies are also showing that it may be affective at treating painful physical symptoms associated with depression as well as stress from urinary incontinence.
Both have side effects that can range from moderate to serious. For a complete list of side effects, click here.
All in all, how affective an SNRI is for you depends on how your body reacts to the medication. One medication may work better than another for you, and not for someone else. Be sure to ask you doctor about the pros and cons of each before you determine whether Effexor or Cymbalta would be right for you.
If you already have a prescription for Effexor or Cymbalta and would like to get it much cheaper than your local drug store, sign up to eDrugSearch.com and start saving today!
- An atypical antidepressant for atypical depression: Consider Wellbutrin if SSRIs have failed
- The Value of Prescription Drug Comparison Shopping: An Illustration
- Merck and insurance companies at cross-purposes over Gardasil
- Was Tom Cruise right about antidepressants?
- 5 Easy Tips To Beat Rising Prescription Drug Prices
- Abilify: No. 1 and climbing
Search Blog Posts
Our Healthcare100 Ranking
Tagsadverse drug reactions Affordable Care Act big pharma Canadian drugs canadian pharmacies canadian pharmacy compare drug prices consumer reports Dave Ramsey discount drugs divine healing Drug costs Drug Importation Drug Prices eDrugSearch.com FDA Fosamax healing scriptures Health 2.0 health blog directory health blogs healthcare100 healthcare reform Hypertension Jehova Rophe Jesus Christ Lipitor Medi Share miracles Obamacare online pharmacy dictionary osteoporosis Pharmacies pharmacy spam Prescription drugs promote health blog Proverbs 3:5-8 reimportation relenza Roche saving money submit health blog Tamiflu The Great Physician The Lord our Healer